標題: Titlebook: Neurodegenerative Diseases; Molecular and Cellul Gary Fiskum Book 1996 Springer Science+Business Media New York 1996 Alzheimer.Amino acid.C [打印本頁] 作者: 熱情美女 時間: 2025-3-21 19:25
書目名稱Neurodegenerative Diseases影響因子(影響力)
作者: 元音 時間: 2025-3-21 22:02 作者: 跟隨 時間: 2025-3-22 00:41 作者: 拾落穗 時間: 2025-3-22 08:04 作者: 營養(yǎng) 時間: 2025-3-22 09:13 作者: CHAR 時間: 2025-3-22 12:55
Intracellular Signalling in Glutamate Excitotoxicity clear that glutamate-induced activation of N-methyl-D-aspartate (NMDA) receptors for about 5 minutes is sufficient to kill neurons, and that death is expressed within 24 hours of glutamate application. Activation of non-NMDA receptors by, for example, kainate requires exposures of more than 30 minutes; death ensues over a similar time frame.作者: Goblet-Cells 時間: 2025-3-22 17:03 作者: LAITY 時間: 2025-3-23 00:27
Lymphocyte Amyloid Precursor Protein mRNA Isoforms in Normal Aging and Alzheimer’s Diseased neurons.. Isoform changes have also been observed in AD and following astrocyte, glial and microglial, cell activation.. It is still unknown which isoforms of APP and which cell types contribute to β/A4 peptide deposition in AD although a number of different cell types are potential contributors to the amyloid load.作者: Dawdle 時間: 2025-3-23 01:21
HIV-1 Coat Protein GP120 Induces Neuronal Injury to Cultured Dopamine Cellsoncentrations (pM) in various neuronal culture systems. as well as modify astrocyte function.. The mechanism(s) by which gp 120 induces neurotoxicity are not understood, but there is evidence that NMDA receptors, Ca. channels, and nitric oxide (NO) are important mediators..作者: 帶來 時間: 2025-3-23 09:21 作者: FIR 時間: 2025-3-23 10:50
A Model for the Expression of Different Glutamate Transporter Proteins from a Rat Astrocyte-Type Gluresults in the incorporation of the amino acid (AA) arginine (R) instead of glutamine (Q) at the R/Q site in the putative intramembranous. domain of the iGluRs. This alteration abolishes the calcium permeability of the edited GluR2 subunit.作者: 兇兆 時間: 2025-3-23 17:49 作者: 妨礙議事 時間: 2025-3-23 20:41
Differential Regulation of APP Secretion by Apolipoprotein E3 and E4tion of apo E plays an important role in the ability of the brain to cope with neuronal injury. This role may also be critical in the ability of the brain to cope with a neurodegenerative illness, such as Alzheimer’s disease.作者: Concerto 時間: 2025-3-23 23:14
Apolipoprotein E Uptake is Increased by Beta-Amyloid Peptides and Reduced by Blockade of the LDL Recng development or following injury.. In the central nervous system, ApoE released from astrocytes in response to injury such as entorhinal cortex lesions in the rat plays a pivotal role in the redistribution of cholesterol and phospholipids during synaptic remodeling and compensatory synaptogenesis..作者: VEIL 時間: 2025-3-24 02:54 作者: conscience 時間: 2025-3-24 08:06 作者: 表狀態(tài) 時間: 2025-3-24 11:17
Guoying Bing,Belinda Wilson,Michael McMillian,Zhehui Feng,Qiping Qi,Hyoung-Chum Kim,Wen Wang,Karl Jeo wurden Verteilungsanalysen zentraler Ressourcen wie Bildung, Status und Einkommen/Verm?gen sowie die demographische Grundgliederung der Bev?lkerung nicht l?nger auf Querschnittuntersuchungen beschr?nkt, sondern dynamisch erweitert (vgl. . 1992: 187). Als Folge dieser Entwicklung wurde zugleich auc作者: REIGN 時間: 2025-3-24 15:22
Norman Hershkowitz,Alexander N. Katchmanen Ressourcen der Angeh?rigen der bürgerlichen und nicht-bürgerlichen . und ihren Modifizierungen im Zeitablauf. Es wird danach gefragt, in welchen sozialen Feldern und R?umen — das sind die . 1980, 1991) — sich die Intelligenz bewegt hat, welche individuellen Struktur-, Handlungs- und Erfahrungsmus作者: 高腳酒杯 時間: 2025-3-24 21:34 作者: 精致 時間: 2025-3-25 01:16
Benjamin Wolozin,Jasna Basaric-Keys,Robert Canter,Yunhua Li,Dudley Strickland,Trey Sunderlandim Deutschen Reich beurteilen zu k?nnen, ist es sinnvoll, zun?chst die Frage zu beantworten, welche Sachverhalte beschrieben und erkl?rt werden sollen. Die Beantwortung dieser Frage ist vor allem deshalb wichtig, weil mit der Charakterisierung der zu ergründenden Sachverhalte deutlich wird, an welch作者: Visual-Acuity 時間: 2025-3-25 04:30 作者: eustachian-tube 時間: 2025-3-25 11:30 作者: 解開 時間: 2025-3-25 12:24 作者: 正式通知 時間: 2025-3-25 17:57 作者: intercede 時間: 2025-3-25 23:22
Long-Term Expression of Proenkephalin and Prodynorphin in the Rat Brain after Systemic Administratioizures in the rat, and produces permanent damage in the CNS, specifically in the limbic system. Systemic injection of kainate results in both short-term and long-term effects on the rat central nervous system (CNS). The excitatory neuronal stimulation by kainate increases the expression of a variety作者: 圓錐體 時間: 2025-3-26 04:11 作者: 取回 時間: 2025-3-26 04:23
A Model for the Expression of Different Glutamate Transporter Proteins from a Rat Astrocyte-Type Gluhere is this phenomenon more obvious and relevant than in the families of genes encoding the ionotropic glutamate (Glu) receptors (iGluRs).. The differences introduced usually affect the physiologic role of the variant protein. For example, the gene encoding the NMDAR1 iGluR makes nine splice varian作者: 討好女人 時間: 2025-3-26 08:48 作者: Hypomania 時間: 2025-3-26 16:01
Neurodegenerative Disease and Oxidative Stress: Insights from an Animal Model of Parkinsonism one of every five individuals. At first glance these disorders seem to have little in common. However, we will briefly review some of the reasons to believe that the diseases are interrelated and, thus, that insights from one can lead to a better understanding of the others. We then will explore a 作者: conference 時間: 2025-3-26 20:36 作者: Relinquish 時間: 2025-3-26 21:33
HIV-1 Coat Protein GP120 Induces Neuronal Injury to Cultured Dopamine Cellsr impairments.. Concomitant with this are CNS disturbances which can include various organic mental disorders.. These CNS disturbances may occur in the absence of opportunistic infections as well as in the absence of direct infection of neurons by HIV-1.. In fact, HIV-1 has only been demonstrated in作者: 先驅(qū) 時間: 2025-3-27 03:41
Platelets as Peripheral Model of Glutamate-Related Excitotoxicity in Parkinson’s Diseases in Parkinson’s Disease (PD).. Defects in mitochondrial enzymes, which make dopaminergic cells more susceptible to oxidative stress, have been found not only in substantia nigra of PD patients., but also in their peripheral tissues.and blood platelets.. Recent studies also indicated that impaired m作者: ordain 時間: 2025-3-27 07:31 作者: Glossy 時間: 2025-3-27 11:42
Biology of APP and its Homologues derived from larger type I integral membrane glycoproteins, termed the amyloid precursor proteins (APP).. APP is a member of a family of homologous amyloid precursor-like proteins (APLPs), including APLP1. and APLP2.. APP, APLP1, and APLP2 show considerable homology in the N-terminal cysteine-rich 作者: ineffectual 時間: 2025-3-27 15:48
Lymphocyte Amyloid Precursor Protein mRNA Isoforms in Normal Aging and Alzheimer’s Diseasentain 770, 751 and 695 amino acids, respectively. The two longer forms of the molecule contain a Kunitz-type serine protease inhibitor domain (KPI). These longer isoforms (APP. and APP.) are the principal species found in non-neuronal cells whereas the shorter APP. is the major form in differentiate作者: 豪華 時間: 2025-3-27 17:53 作者: 斗爭 時間: 2025-3-27 23:19 作者: Gratulate 時間: 2025-3-28 02:11 作者: 小卷發(fā) 時間: 2025-3-28 09:10
Mutations of Human Cu, Zn Superoxide Dismutase Expressed in Transgenic Mice Cause Motor Neuron Disea and have an unknown etiology.. However, about 10–15% of all ALS cases are inherited. An adultonset, autosomal dominantly inherited trait is the predominant form., although there is a rare, recessively inherited childhood-onset form of ALS in which survival can be quite long.. In 1991, a fraction of作者: anaerobic 時間: 2025-3-28 11:49 作者: commute 時間: 2025-3-28 16:02 作者: packet 時間: 2025-3-28 20:36 作者: 能得到 時間: 2025-3-29 00:40 作者: 高貴領(lǐng)導(dǎo) 時間: 2025-3-29 03:53
Guoying Bing,Belinda Wilson,Michael McMillian,Zhehui Feng,Qiping Qi,Hyoung-Chum Kim,Wen Wang,Karl Jechen . das Programm der .: ?Lebensverl?ufe sind das Ergebnis einer Vielzahl von Einflüssen: ?konomisch und politisch bestimmte Gelegenheitsstrukturen, kulturell gepr?gte Vorstellungen, gesetzliche Altersnormen, institutionalisierte Positionssequenzen und überg?nge, individuelle Entscheidungen, Sozia作者: 寒冷 時間: 2025-3-29 10:50 作者: Foreshadow 時間: 2025-3-29 12:11 作者: insurgent 時間: 2025-3-29 17:09 作者: 移植 時間: 2025-3-29 22:38 作者: 人類的發(fā)源 時間: 2025-3-30 02:19 作者: 平息 時間: 2025-3-30 06:15
Mark E. Gurney,Arlene Y. Chiu,Mauro C. Dal Canto,John Q. Trojanowski,Virginia M.-Y. Lee Im Gegensatz zu dem Ausdruck ?sozial erzeugte” wird hier auf die Stellung von Menschen in sozialen Beziehungsgefügen als Ursache von sozialer Ungleichheit verwiesen, in beiden Definitionen wird aber deutlich gemacht, dass es sich um eine sozial bedingte Ungleichheit handelt. In der Definition von H作者: 記成螞蟻 時間: 2025-3-30 11:40 作者: Humble 時間: 2025-3-30 14:08
Biology of APP and its Homologues APLPs in the mammalian nervous system are far from clear, although several studies have suggested that APP play roles in cell-cell or cell-matrix interactions,. calcium hemostasis,. growth promoting activities,. and the formation/maintenance of synapses .. More recently, investigations in cultured 作者: 小木槌 時間: 2025-3-30 18:00
The Non-Amyloid-β Component of Alzheimer’s Disease Plaque Amyloid: Comparative Analysis Suggests a Nphosphorylated on serine residues, and have suggested it is also phosphorylated on tyrosine.; they named the protein Phosphoneuroprotein-14-kDa (PNP-14). More recently, Jakes et al.., using an antibody originally raised against paired helical filaments, detected two forms of the same human protein, 作者: SCORE 時間: 2025-3-30 21:11
Mutations of Human Cu, Zn Superoxide Dismutase Expressed in Transgenic Mice Cause Motor Neuron Diseaf Superoxide (O.×.) to hydrogen peroxide (H.O.). The copper ion provides the redox center for the dismutation of Superoxide, while the zinc ion plays a structural role. Three different genes encoding Superoxide dismutases are present in the human genome. All three enzymes contain a transition metal 作者: Limited 時間: 2025-3-31 01:29
Davide Trotti,Niels C. Danbolt,Barbara Lodi Rizzini,Paola Bezzi,Daniela Rossi,Giorgio Racagni,Andrea作者: 好忠告人 時間: 2025-3-31 05:58 作者: 替代品 時間: 2025-3-31 12:56 作者: 果核 時間: 2025-3-31 13:25 作者: 抱負 時間: 2025-3-31 18:06 作者: Seminar 時間: 2025-3-31 22:10
Sangram S. Sisodia Ph.D.,Gopal Thinakaran Ph.D.,Cornelia S. von Koch B.A.,Hilda H. Slunt B.S.,A. Jan作者: FECT 時間: 2025-4-1 02:42
Richard P. Ebstein,Lubov Nemanov,Gregory Lubarski,Marina Dano,Teres Trevis,Amos Korczyn作者: 同步信息 時間: 2025-4-1 08:19
P. A. Yerramilli-Rao,O. Garofalo,P. N. Leigh,J.-M. Gallo作者: terazosin 時間: 2025-4-1 12:56 作者: –LOUS 時間: 2025-4-1 15:59
978-1-4899-0211-5Springer Science+Business Media New York 1996作者: 我怕被刺穿 時間: 2025-4-1 18:57 作者: Esophagus 時間: 2025-4-1 22:46
Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposiahttp://image.papertrans.cn/n/image/663975.jpg作者: 蒼白 時間: 2025-4-2 05:38 作者: Sinus-Rhythm 時間: 2025-4-2 10:12 作者: 殘酷的地方 時間: 2025-4-2 12:24
Book 2018ige Deutung des Ph?nomens und um die Zust?ndigkeit und L?sungskompetenz der involvierten Instanzen verbunden. Manfred Schnabel untersucht diesen ?Deutungskampf“ mit den Instrumenten einer politischen Diskursanalyse. Unter Rekurs auf poststrukturalistische Konzepte werden hegemoniale Strukturen in de
