作者: Substitution 時間: 2025-3-21 22:41
Antagonists of Folic Acid and Vitamin B6 in Regulation of S-Adenosylmethionine and S-Adenosylhomocyzone) and related compounds is due to the inhibition of SAM decarboxylase (EC 4.1.1.50) in malignant tissue. The antitumor activity of cycloleucine (the conformational analogue of L-methionine) was suggested to be due to inhibition of L-methionine conversion to SAM catalyzed by SAM synthetase (EC 2.5.1.6)..作者: staging 時間: 2025-3-22 04:18 作者: foliage 時間: 2025-3-22 07:23 作者: POWER 時間: 2025-3-22 09:01
Methylase Mechanisms: Steric Constraints and Modes of Catalysis,ith more recent results of our chemical mechanism studies. Ultimately, we would like to use this information in the design of potent, specific multisubstrate adduct (“transition state analog”) inhibitors (3) of these reactions.作者: organism 時間: 2025-3-22 13:11
Adenosylmethionine as a Precursor for Nucleic Acids Modification,e transfer of both the adenosyl moiety and of the 3-amino-3-carboxypropyl group have been described in very few instances.: the acceptor molecules are enzyme proteins for the adenosyl moiety., and transfer RNA (tRNA) for the 3-amino-3-carboxypropyl group..作者: 過份 時間: 2025-3-22 17:15 作者: Traumatic-Grief 時間: 2025-3-23 00:18 作者: Suppository 時間: 2025-3-23 04:49
Involvement of S-Adenosylmethionine in Brain Phospholipid Metabolism,hway, first demonstrated in liver by Bremer and Greenberg. and successively described in this tissue by several authors, has not been however unequivocally demonstrated in brain, and conflicting data have been produced in this connection..作者: DAFT 時間: 2025-3-23 07:14
Homocysteine Biosynthesis in Plants,s eventually to inorganic sulfate. Plants complete the cycle of sulfur by reductive assimilation of inorganic sulfate to methionine (and cysteine) (Siegel, 1975), and are thus the ultimate source of methionine in most animal diets.作者: Regurgitation 時間: 2025-3-23 12:22
Inhibition of the Synthesis of Glutathione, Glutamine, and Glutamate by Certain Methionine Derivati across cell membranes by similar - in some instances perhaps identical - systems. Some enzymes that interact with methionine and glutamate or with derivatives of these amino acids are listed in Table I.作者: Kidney-Failure 時間: 2025-3-23 16:14
A. Kj?r,G. Grue-S?rensen,E. Kelstrup,J. ?gaard Madsen作者: antiquated 時間: 2025-3-23 19:40 作者: cruise 時間: 2025-3-24 01:32 作者: 食道 時間: 2025-3-24 04:19 作者: anthesis 時間: 2025-3-24 09:50
Adriana Oliva,Patrizia Galletti,Vincenzo Zappia,Woon Ki Paik,Sangduk Kimeases in humans. Thus, mutations in . gene lead to pontocerebellar hypoplasia type 2D, a neurodegenerative disease. Sedaghatian disease is caused by . mutations. Some of these patients show malformations of the central nervous system. A homozygous mutation in the . causes generalized epilepsy. Heari作者: 貧窮地活 時間: 2025-3-24 14:20 作者: 小教堂 時間: 2025-3-24 15:10
John Giovanelli,S. Harvey Mudd,Anne H. Datkoeases in humans. Thus, mutations in . gene lead to pontocerebellar hypoplasia type 2D, a neurodegenerative disease. Sedaghatian disease is caused by . mutations. Some of these patients show malformations of the central nervous system. A homozygous mutation in the . causes generalized epilepsy. Heari作者: 憤憤不平 時間: 2025-3-24 21:53
Alton Meistereases in humans. Thus, mutations in . gene lead to pontocerebellar hypoplasia type 2D, a neurodegenerative disease. Sedaghatian disease is caused by . mutations. Some of these patients show malformations of the central nervous system. A homozygous mutation in the . causes generalized epilepsy. Heari作者: Range-Of-Motion 時間: 2025-3-25 02:57
John A. Sturmanresearch, in order to avoid misleading and biased evaluations of selenium’s effects. These include the use of central nervous system indicator of exposure such as cerebrospinal fluid, and the implementation of speciation analysis, due to the different toxic and nutritional properties of the various 作者: 吞吞吐吐 時間: 2025-3-25 04:41 作者: 思想靈活 時間: 2025-3-25 09:02 作者: 鞠躬 時間: 2025-3-25 14:23 作者: Lament 時間: 2025-3-25 18:22 作者: Respond 時間: 2025-3-25 20:30
Book 1980blication of the proceedings. Through the cooperation of the authors in providing "camera ready" copies of their manuscripts, the good efforts of the Orga- nizing Committee, and the Plenum Press Publishing Co., it has been possible to publish this book within a few months of the meeting.作者: 數(shù)量 時間: 2025-3-26 00:24
e rapid publication of the proceedings. Through the cooperation of the authors in providing "camera ready" copies of their manuscripts, the good efforts of the Orga- nizing Committee, and the Plenum Press Publishing Co., it has been possible to publish this book within a few months of the meeting.978-1-4613-3047-9978-1-4613-3045-5作者: 漂浮 時間: 2025-3-26 06:03 作者: Palliation 時間: 2025-3-26 12:03 作者: 不易燃 時間: 2025-3-26 16:34
Giulio L. Cantoni,Peter K. Chiangdependent systems. All three thioredoxin reductases contain selenocysteine as their penultimate amino acid and keep thioredoxins in their reduced, active state. Cytosolic thioredoxin reductase (TXNRD1) and mitochondrial thioredoxin reductase (TXNRD2) are directly involved in cell proliferation and c作者: crease 時間: 2025-3-26 20:01 作者: Horizon 時間: 2025-3-26 21:46
Alton Meistere provided a new perspective on the function of selenoproteins in brain. Since then, genetic studies in mice have revealed that some selenoproteins are indispensable to normal brain function. Neurodegeneration of GABAergic interneurons (PV+ neurons and Purkinje cells in cerebellum) was observed in .作者: Decibel 時間: 2025-3-27 01:17
John A. Sturmant, especially in its inorganic forms, toward motor neurons. The epidemiological evidence, in association with laboratory and veterinary findings, linking selenium exposure and ALS risk was originally suggested by the increased ALS mortality in an area characterized by high selenium content in soil, 作者: Cupidity 時間: 2025-3-27 05:39 作者: 命令變成大炮 時間: 2025-3-27 09:40
Vincenzo Zappia,Maria Cartenì-Farina,Giovanna Cacciapuoti,Adriana Oliva,Agata Gambacortat, especially in its inorganic forms, toward motor neurons. The epidemiological evidence, in association with laboratory and veterinary findings, linking selenium exposure and ALS risk was originally suggested by the increased ALS mortality in an area characterized by high selenium content in soil, 作者: aneurysm 時間: 2025-3-27 13:51 作者: ABOUT 時間: 2025-3-27 18:35 作者: magnate 時間: 2025-3-27 23:55
Adenosylmethionine as a Precursor for Nucleic Acids Modification,olecular species within the cell.. The reaction involves nucleophilic attack to one of the three carbon atoms adjacent to the electron-deficient trivalent sulfur (see Figure 1) and is catalyzed by specific enzymes.. Whereas the transfer of the methyl group occurs in a large variety of reactions., th作者: 發(fā)現(xiàn) 時間: 2025-3-28 02:35 作者: 付出 時間: 2025-3-28 06:50
Effect of S-Adenosyl-L-Methionine and S-Adenosyl-L-Homocysteine Derivatives on Protein Methylation, the intervening years, it has been recognized that there exist three methylated lysines, ?-N-mono-, ?-N-di- and ?-N-trimethyllysine. In addition, arginine histidine and dicarboxylic amino acid residues of certain proteins were also found to be methylated.作者: Dislocation 時間: 2025-3-28 14:30
The Role of S-Adenosylhomocysteine and S-Adenosylhomocysteine Hydrolase in the Control of Biologicamethyl donor by Scarano and Cantoni. in 1954. Over the last 25 years, and especially in the last three or four years, AdoHcy has attracted increasing attention because it has become well established that AdoHcy is a competitive inhibitor of many, if not most, of the reactions in which AdoMet partici作者: largesse 時間: 2025-3-28 17:11 作者: 追逐 時間: 2025-3-28 20:28 作者: 冒失 時間: 2025-3-28 23:46
Methionine Metabolism in Developing Neural Tissue,ivities of enzymes involved, concentrations of intermediates and end-products, and changes in the overall use of the carbon skeleton of the methionine molecule. This article will describe and discuss these changes in developing neural tissue, and compare and contrast them to those taking place in li作者: DAFT 時間: 2025-3-29 04:46
Antagonists of Folic Acid and Vitamin B6 in Regulation of S-Adenosylmethionine and S-Adenosylhomocy methyl-group donor in all reactions of biological methylation except those involved in the biosynthesis of L-methionine.. Some biochemical functions of SAM may be critical for the viability of malignant cells. The polyamines which arise from decarboxylated products of SAM and L-ornitine perform spe作者: 搖擺 時間: 2025-3-29 09:37
,Recent Studies on the Metabolism of 5’-Methylthioadenosine,molar amounts in several prokaryotes and eukaryotes.. Although the chemical structure of this thioether was elucidated in 1924., its biological role as product of methionine metabolism was demonstrated by Schlenk in 1952., even before the discovery of its precursor Ado-Met..作者: Synchronism 時間: 2025-3-29 13:45 作者: NOVA 時間: 2025-3-29 17:43
Cysteine Dioxygenase of Rat Liver: Some Properties and its Significance on Cysteine Metabolism of Ras a key intermediate of cysteine metabolism to hypotaurine, taurine, isethionic acid, pyruvate and sulfate in mammalian tissues.. Recently, rat liver supernatant has been shown to contain an enzyme catalyzing the oxidation of cysteine to CSA.. The enzyme responsible for the catalysis was shown to d作者: Crohns-disease 時間: 2025-3-29 19:52 作者: landmark 時間: 2025-3-30 02:10
Sulfur Amino Acids in the Reproductive Tract of Male Guinea Pigs, Rats, Mice and Several Marine Aniee amino acids of several of the responsive tissues. was determined as an aid in the delineation of the anabolic action of androgens. On analysis of the seminal vesicles of the guinea pig. an unknown amino acid peak appeared just before taurine on slight adjustment of the pH of the elution buffer. T作者: fluoroscopy 時間: 2025-3-30 06:51
Hypotaurine in the Reproductive Tract,lectrophoresis at pH 4.5 and at pH 1.9 followed by ascending chromatography in the solvent system butanol-acetic acid-water (12:3:5). The amino acids were detected with ninhydrin. Leucine, phenylalanine, valine, alanine, glycine, serine and glutamic acid were present in readily detectable amounts; b作者: Angioplasty 時間: 2025-3-30 08:37
Stereochemical Aspects of Transmethylations of Potential Biological Interest,been reported as a constituent of asparagus, . jack beans, . pelargonium and mint leaves, . green tea, . soybean meal, . celery, . tomatoes, . sweet corn, . potatoes, . apples, . and milk. . The amazingly wide distribution of . justifies inquiries into its chemistry, biosynthesis, metabolism, and biological significance.作者: Incommensurate 時間: 2025-3-30 14:29
Effect of S-Adenosyl-L-Methionine and S-Adenosyl-L-Homocysteine Derivatives on Protein Methylation, the intervening years, it has been recognized that there exist three methylated lysines, ?-N-mono-, ?-N-di- and ?-N-trimethyllysine. In addition, arginine histidine and dicarboxylic amino acid residues of certain proteins were also found to be methylated.作者: 尊嚴(yán) 時間: 2025-3-30 19:19
The Role of S-Adenosylhomocysteine and S-Adenosylhomocysteine Hydrolase in the Control of Biologicamethyl donor by Scarano and Cantoni. in 1954. Over the last 25 years, and especially in the last three or four years, AdoHcy has attracted increasing attention because it has become well established that AdoHcy is a competitive inhibitor of many, if not most, of the reactions in which AdoMet participates 2–13.作者: capsule 時間: 2025-3-30 22:58 作者: Affiliation 時間: 2025-3-31 03:56 作者: 表示向前 時間: 2025-3-31 06:11 作者: Urea508 時間: 2025-3-31 11:57
https://doi.org/10.1007/978-1-4613-3045-5Calcium; Glutamat; Glutamin; Oxidation; amino acid; biochemistry; biology; catalysis; chemistry; metabolism; m作者: 全部 時間: 2025-3-31 16:15 作者: 拍下盜公款 時間: 2025-3-31 21:33
Two Different Modes of Synthesis and Transformation of Cysteine (and Related Amino Acids) by PyridoA variety of amino acids with electrophilic substituents (RO, RS, indolyl, etc.) in positions β or γ are of general biological significance as protein constituents and metabolic intermediates, or in more restricted roles as detoxication products or secondary nitrogen reserves (in plants).作者: languid 時間: 2025-3-31 22:30
Cysteamine Pathway of Taurine Biosynthesis,Three main routes have been discovered in animals able to produce taurine (TAU), called the cysteine sulfinic acid (CSA) pathway, the cysteamine pathway and the inorganic pathway.作者: 精密 時間: 2025-4-1 03:51 作者: nominal 時間: 2025-4-1 06:26 作者: Compatriot 時間: 2025-4-1 11:59
978-981-97-6158-6The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
