標題: Titlebook: N-Oxidation of Drugs; Biochemistry, pharma P. Hlavica (Full Professor of Pharmacology and Tox Book 1991 Chapman & Hall 1991 Drogen.Oxidatio [打印本頁] 作者: formation 時間: 2025-3-21 16:25
書目名稱N-Oxidation of Drugs影響因子(影響力)
書目名稱N-Oxidation of Drugs影響因子(影響力)學(xué)科排名
書目名稱N-Oxidation of Drugs網(wǎng)絡(luò)公開度
書目名稱N-Oxidation of Drugs網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱N-Oxidation of Drugs被引頻次
書目名稱N-Oxidation of Drugs被引頻次學(xué)科排名
書目名稱N-Oxidation of Drugs年度引用
書目名稱N-Oxidation of Drugs年度引用學(xué)科排名
書目名稱N-Oxidation of Drugs讀者反饋
書目名稱N-Oxidation of Drugs讀者反饋學(xué)科排名
作者: 巧思 時間: 2025-3-21 21:50
ers of returnees had been in business overseas before returning to China. Over this time, Chinese intellectuals have been reoriented toward the business world. As the success of high-tech zones such as Zhongguancun have shown, returnee scientists are now avidly pursuing entrepreneurial opportunities作者: 發(fā)生 時間: 2025-3-22 03:28
T. E. Eling,J. F. Curtis,D. C. Thompson,J. Van der Zee,R. P. Masoners of returnees had been in business overseas before returning to China. Over this time, Chinese intellectuals have been reoriented toward the business world. As the success of high-tech zones such as Zhongguancun have shown, returnee scientists are now avidly pursuing entrepreneurial opportunities作者: Incisor 時間: 2025-3-22 05:04
B. Clement,Th. K?mpchen characteristic fluid flow cross section and its uniformity in the flow direction. These inherent characteristics of the tubular module yield, with proper design, advantages of minimal fouling tendency, higher fractional recovery operation, and ease of physical in situ cleaning of the membrane surfa作者: 舊病復(fù)發(fā) 時間: 2025-3-22 11:56
K. K. Midha,T. J. Jaworski,E. M. Hawes,G. McKay,J. W. Hubbard,M. Aravagiri,S. R. Mardersalination by reverse osmosis. Nevertheless, most of the procedures developed for manufacturing membranes were formulated empirically, and the understanding of the factors governing membrane structure and its characteristics is still poor. One of the most severe problems associated with the practica作者: FISC 時間: 2025-3-22 13:58 作者: MEAN 時間: 2025-3-22 18:59
D. M. Zieglerthat can provide purified water at technologically significant rates. The experiments reported by Loeb and Sourirajan[1], which were subsequently shown[2,3] to yield membranes having a relatively dense surface layer followed by a gradual transition to a supporting macroporous structure, initiated th作者: facilitate 時間: 2025-3-22 21:59 作者: 機密 時間: 2025-3-23 02:00
D. E. Williamson plant. It also explains how these systems and their online readings are used in combination with monitoring of the SWRO plant’s treatment processes by manual sampling of the SWRO feed, product water, wastewater, and process chemicals with subsequent laboratory analysis. The range of information a作者: 鄙視 時間: 2025-3-23 06:06 作者: 放逐某人 時間: 2025-3-23 10:08 作者: Constitution 時間: 2025-3-23 16:13 作者: Exposure 時間: 2025-3-23 21:57
A. K. Cho,J. D. Duncan,J. M. Fukutoof 2:1. However, it was demonstrated that two-dimensional methods fail to account for “out-of-plane” motions; therefore a 3-dimensional system, especially an electromagnetic system, seems to be the most suitable method to register the three-dimensional movement of the shoulder. By using the “Flock o作者: Ardent 時間: 2025-3-24 00:50
P. J. O’Brien,S. Jatoe,L. G. McGirr,S. Khan loop, understand the performance of devices, and validate assumptions made and methods used during preclinical testing. In this chapter, we provide an overview of the implant retrieval analysis performed at the Implant Research Center at Drexel University on reverse total shoulder systems retrieved作者: epidermis 時間: 2025-3-24 03:05 作者: Felicitous 時間: 2025-3-24 07:20 作者: 朋黨派系 時間: 2025-3-24 12:51 作者: 針葉樹 時間: 2025-3-24 15:01 作者: 確定 時間: 2025-3-24 19:53
Formation of aromatic amine free radicals by prostaglandin hydroperoxidase and peroxyl radicals: ananes via either the cyclo-oxygenase or lipoxygenase pathways (.). Prostaglandin H synthase (PHS) is the initial enzyme in the cyclo-oxygenase pathway which commits AA to the formation of prostaglandins (Fig. 1.1). Two catalytic activities copurify with PHS, cyclo-oxygenase and peroxidase (.). The cyc作者: 期滿 時間: 2025-3-25 01:36 作者: URN 時間: 2025-3-25 05:53
Radioimmunoassay and other methods for trace analysis of ,-oxide compoundsde of a tertiary aliphatic amine such as trimethylamine, or tertiary arylalkylamine such as dimethylphenylamine, or heteroaromatic amine such as pyridine or quinoline. The first two types are referred to here as aliphatic tertiary amines. It is established that there are chemical and metabolic diffe作者: 俗艷 時間: 2025-3-25 07:43
Mechanism, multiple forms and substrate specificities of flavin-containing mono-oxygenasestionally versatile molecule that in different microenvironments carries out a variety of different biological redox functions. Most of these are well known and the present discussion will be restricted to a subgroup of flavin-dependent mono-oxygenases that catalyse the oxidation of an exceptionally 作者: Picks-Disease 時間: 2025-3-25 14:57 作者: PLIC 時間: 2025-3-25 18:35
Factors regulating the activity of the rabbit lung flavin-containing mono-oxygenaseZiegler, 1988). As is the case with the other major monooxygenase system, the cytochrome .-450-dependent mixed-function oxidase, FMO is found in highest concentration in liver and requires NADPH and 0. for activity. However, unlike the .-450 system, mammalian FMO is not inducible by phenobarbital, 3作者: 冥界三河 時間: 2025-3-25 21:50
Human pharmacogenetics of nitrogen oxidationshe microsomal mixed function mono-oxygenases, commonly referred to as the cytochrome P-450s but also several non-cytochrome .-450 enzymes including the cytosolic alcohol dehydrogenase and the microsomal flavin-containing mono-oxygenase, otherwise known as Ziegler’s enzyme. Although such enzymes medi作者: cognizant 時間: 2025-3-26 03:34
Roles of aminium radical intermediates in the biotransformation of dihydropyridines, cycloalkylaminens, 1987; Nelson and Harvison, 1987Guengerich, 1988; Butler et al., 1989Shimada et al., 1989). Products of the oxidation of different amines include hydroxylamines, .-oxides, pyridines, dealkylation products and other compounds. A proper understanding of the catalytic mechanism of .-450 is important作者: 溝通 時間: 2025-3-26 07:15 作者: 清唱劇 時間: 2025-3-26 10:48 作者: Lipoprotein 時間: 2025-3-26 14:37
Molecular activation mechanisms involved in arylamine cytotoxicity: peroxidase productstonucleophilic groups on informational cellular macromolecules such as DNA (Miller, 1970). Much attention has been focused on the .-oxidation of arylamines and arylamides by cytochrome .-450-dependent hepatic mixed function oxidases. However, peroxidases (donor-H.O. oxidoreductases, EC 1.11.1.7) als作者: 無可非議 時間: 2025-3-26 19:20 作者: exhibit 時間: 2025-3-26 22:51 作者: Moderate 時間: 2025-3-27 03:24
Purification and characterization of rat hepatic acetyltransferaseome from occupational, environmental, dietary and pharmacological sources. Structurally these compounds are similar in that they all have, or can be metabolized to arylhydroxylamine derivatives. Biological experiments revealed that these metabolites were likely to be more closely related to the adve作者: 智力高 時間: 2025-3-27 09:17 作者: 帳單 時間: 2025-3-27 10:29
metabolism of ,-oxidese and minoxidil. In both these cases some of the major metabolites in man either retain the .-oxide group as such or form conjugates thereof (Thomas and Harpootlian, 1975; Johnson et al., 1983; Boxenbaum et al., 1977; also see Chapter 4).作者: SAGE 時間: 2025-3-27 16:25
The Application of ,N-NMR in the Analysis of ,-Oxygenated amidines and guanidines2.1) and is thus not appropriate for high resolution studies. As a result of quadrupole relaxation, the line widths of the signals are very broad and relatively sharp resonance lines can be observed only in special cases.作者: 把…比做 時間: 2025-3-27 21:38
Mechanism, multiple forms and substrate specificities of flavin-containing mono-oxygenasesknown and the present discussion will be restricted to a subgroup of flavin-dependent mono-oxygenases that catalyse the oxidation of an exceptionally broad range of substrates . a mechanism distinctly different from all other mono-oxygenases or oxidases.作者: 事與愿違 時間: 2025-3-27 22:07 作者: CARE 時間: 2025-3-28 04:32
Purification and characterization of rat hepatic acetyltransferaserse genotoxic properties of aromatic amines or nitroarenes than the parent compounds themselves. Although it was demonstrated that some of these potential metabolites could react with nucleic acid in acidic media (e.g. pH 5) (Kriek, 1965), many had only marginal reactivity at pH values that were likely to be encountered in physiological systems.作者: 初次登臺 時間: 2025-3-28 09:05
Formation of aromatic amine free radicals by prostaglandin hydroperoxidase and peroxyl radicals: anaroxidase subsequently reduces the hydroperoxide to the corresponding alcohol, PGH.. PGH. is then converted into a variety of other prostanoid metabolites, including thromboxanes, prostacyclin, and PGs E. and F..作者: 縮影 時間: 2025-3-28 11:07 作者: Bureaucracy 時間: 2025-3-28 17:30 作者: perimenopause 時間: 2025-3-28 22:13
Human pharmacogenetics of nitrogen oxidationsever their presence has also been demonstrated in other tissues including lung, kidney and intestine. Furthermore, the enzymes of the gut flora are also known to be important mediators of the metabolism of certain xenobiotics.作者: 含水層 時間: 2025-3-29 02:04
F. P. Guengerich,A. Bondon,R. G. B?cker,T. L. Macdonald作者: 發(fā)微光 時間: 2025-3-29 04:27
Factors regulating the activity of the rabbit lung flavin-containing mono-oxygenase al., 1985; Dannan et al, 1986; Tynes and Philpot, 1987). Studies employing gonadectomy of young animals indicate a role for the sex steroids in regulation of FMO (Duffel et al, 1981; Dannan et al, 1986).作者: 掙扎 時間: 2025-3-29 08:19 作者: Cervical-Spine 時間: 2025-3-29 12:42
Molecular activation mechanisms involved in arylamine cytotoxicity: peroxidase productsy peroxidases (O’Brien, 1984,O’Brien, 1985,O’Brien, 1988a,O’Brien, 1988b; Meunier, 1987) or the peroxidase activity of prostaglandin H synthase (Boyd and Eling, 1985; Josephy, 1988). Furthermore, suggestive evidence for in vivo peroxidase activation has recently appeared. Thus about 20% of the DNA a作者: Conquest 時間: 2025-3-29 18:15
Reduction and conjugation reactions of ,-oxidesumulated on nitrogen oxidation (Bridges et al., 1972; Gorrod, 1978; Gorrod and Damani, 1985 and references cited therein), the further metabolism of the .-oxygenated intermediates has not been studied as extensively or systematically. In particular, the reversible nature of certain .-oxygenations un作者: Foregery 時間: 2025-3-29 21:09
P. Hlavica (Full Professor of Pharmacology and Tox作者: BROOK 時間: 2025-3-30 00:17 作者: 使人煩燥 時間: 2025-3-30 08:07 作者: LASH 時間: 2025-3-30 09:27
T. E. Eling,J. F. Curtis,D. C. Thompson,J. Van der Zee,R. P. Masontaining investment capital and physical space for their new business ventures, while also assisting them in dealing with bureaucratic red tape. Statistics show that governments from the national to local levels and universities have jointly established more than 150 science venture parks containing 作者: 職業(yè)拳擊手 時間: 2025-3-30 13:33
B. Clement,Th. K?mpchen the cost of polymer itself as is possible. Since, in the case of cellulose acetate, approximately 1/64 pound of polymer is required to produce one square foot of membrane 8 mils thick[1], then the cost of polymer is slightly greater than 1 cent per square foot of membrane or less than 1/10 of a cen作者: 助記 時間: 2025-3-30 16:52 作者: Urgency 時間: 2025-3-30 21:05 作者: menopause 時間: 2025-3-31 02:54 作者: 大量殺死 時間: 2025-3-31 06:33
P. Hlavica,I. Gollyseawater components. Another section of Chap. 3 deals with the calculation of chemical equilibria in seawater, in particular the CO./bicarbonate/carbonate equilibrium and the boric acid/borate equilibrium, in each case based on stoichiometric as well as thermodynamic modelling.
