作者: 千篇一律 時(shí)間: 2025-3-21 22:38
Elena Guffart,Marco Prinzporto is the centre of its metropolitan area (Metropolitan Area of Oporto – AMP) and the second-largest city in Portugal. It is closely connected to an extremely industrialised area (in the northwest) to which it provides the main services. Links with the eastern hinterland suffer from underdevelope作者: 永久 時(shí)間: 2025-3-22 02:18 作者: 提名的名單 時(shí)間: 2025-3-22 07:00 作者: 換話(huà)題 時(shí)間: 2025-3-22 08:58
Marcus Augusto-Oliveira,Marie-ève Tremblay,Alexei Verkhratskyenced across populations and subgroups. Moreover, guidance on how to further enhance understandings of resilience and expand resilience research and policy applied to vulnerable groups of aging persons is in its infancy. For example, existing definitions of resilience have overlooked the lived exper作者: TOXIC 時(shí)間: 2025-3-22 15:38
Olga Garaschuk,Alexei Verkhratskyactice. Proponents of the concept argue resilience research challenges stereotypes of aging, an important consideration in societies faced by ageism and discrimination. It has shown how some older people are able to ‘beat the odds’, providing insights into adjustment processes that might be generali作者: 母豬 時(shí)間: 2025-3-22 19:27 作者: corpus-callosum 時(shí)間: 2025-3-22 21:50 作者: averse 時(shí)間: 2025-3-23 02:56 作者: 我說(shuō)不重要 時(shí)間: 2025-3-23 07:07
Haley A. Vecchiarelli,Luana Tenorio Lopes,Rosa C. Paolicelli,Beth Stevens,Hiroaki Wake,Marie-ève Tree field if greater effort were directed toward some empirically-based taxonomy of risk and protective factors and resiliency processes that would serve as an organizational tool for existing (and ongoing) research findings across disciplines and specialty areas. The research literature on resilience作者: 休戰(zhàn) 時(shí)間: 2025-3-23 12:05 作者: 長(zhǎng)矛 時(shí)間: 2025-3-23 14:53 作者: 迫擊炮 時(shí)間: 2025-3-23 18:29
Linh Le,Kazuya Miyanishi,Junya Tanaka,Ania K. Majewskae field if greater effort were directed toward some empirically-based taxonomy of risk and protective factors and resiliency processes that would serve as an organizational tool for existing (and ongoing) research findings across disciplines and specialty areas. The research literature on resilience作者: 修改 時(shí)間: 2025-3-24 01:54 作者: mercenary 時(shí)間: 2025-3-24 02:42
Paloma Marinho Jucá,érica de Almeida Duque,Luiza Helena Halas Covre,Kairo Alan Albernaz Mariano,Caroe field if greater effort were directed toward some empirically-based taxonomy of risk and protective factors and resiliency processes that would serve as an organizational tool for existing (and ongoing) research findings across disciplines and specialty areas. The research literature on resilience作者: Nefarious 時(shí)間: 2025-3-24 08:05
General Pathophysiology of Microglia ensuring proper development, activity, and plasticity of neurones and glial cells but also maintaining and restoring homeostasis when faced with various challenges across the lifespan. This chapter is dedicated to the current understanding of microglia, including their beneficial versus detrimental作者: EXUDE 時(shí)間: 2025-3-24 12:30 作者: 使迷醉 時(shí)間: 2025-3-24 17:07 作者: delta-waves 時(shí)間: 2025-3-24 19:30
Visualization, Fate Mapping, Ablation, and Mutagenesis of Microglia in the Mouse Brain) transcriptomics have yielded many fascinating new insights into these intriguing immune cells at the interface with the central nervous system (CNS), both in small animal models and human samples. In parallel, tools developed by advanced mouse genetics have revealed the unique ontogeny of microgli作者: 無(wú)孔 時(shí)間: 2025-3-25 01:36 作者: 小母馬 時(shí)間: 2025-3-25 03:27
Receptors on Microgliaitage and newly acquired neural specialisation. Microglia possess, depending on the particular context, receptors to neurotransmitters and neuromodulators as well as immunocompetent receptors. This rich complement allows microglial cells to monitor the functional status of the nervous system, contri作者: motor-unit 時(shí)間: 2025-3-25 08:38
Calcium Signalling in Microgliaa. concentration ([Ca.].) are generated in response to physiological and pathological stimuli. Parameters of these intracellular Ca. signals are defined by Ca. signalling toolkits that may change with age or context therefore increasing adaptive capabilities of microglia. Main Ca. signalling pathway作者: formula 時(shí)間: 2025-3-25 13:38 作者: 過(guò)時(shí) 時(shí)間: 2025-3-25 16:01 作者: Noisome 時(shí)間: 2025-3-25 23:56
Microglia Colonization Associated with Angiogenesis and Neural Cell Developmentoliferation, differentiation, and neurovascularization. As microglia colonize and establish within the developing nervous system, they assume a neural-specific identity and contribute to key developmental events. Their association around blood vessels implicates them in development of the vascular s作者: Allure 時(shí)間: 2025-3-26 03:50 作者: 百靈鳥(niǎo) 時(shí)間: 2025-3-26 05:59
Microglial Modulation of Synaptic Maturation, Activity, and Plasticityxperimental evidence that microglia modulate neuronal and synaptic activity during normal development and in adults. We show that microglia can regulate the maturation and function of both inhibitory and excitatory synapses that can be stimulated or repressed. We further review the fact that these r作者: 手銬 時(shí)間: 2025-3-26 09:40 作者: expire 時(shí)間: 2025-3-26 12:59
Microglial Regulation of Sleep and Wakefulnessaracterized, it is increasingly recognized that neurons are not the sole conductor orchestrating the rhythmic cycle of sleep and wakefulness. In the central nervous system, microglia have emerged as an important player in sleep regulation. Within the last two decades, microglia have gained substanti作者: 火海 時(shí)間: 2025-3-26 20:43
Roles in Innate Immunityy roles during the initiation, propagation, and resolution of inflammation. The discovery of resident adaptive immune cells in the CNS has unveiled a relationship between microglia and adaptive immune cells for CNS immune-surveillance during health and disease. The interaction of microglia with elem作者: Favorable 時(shí)間: 2025-3-26 21:16
Microglia and Systemic Immunityrain microenvironment. While traditionally regarded as a part of the innate immune system, recent research has highlighted their role in adaptive immunity. The CNS is no longer considered an immune-privileged organ, and increasing evidence suggests bidirectional communication between the immune syst作者: Obstacle 時(shí)間: 2025-3-27 01:37 作者: 祖?zhèn)髫?cái)產(chǎn) 時(shí)間: 2025-3-27 06:14 作者: nettle 時(shí)間: 2025-3-27 12:06
Evolution of Microgliaa being the only CNS-resident immune cells was outdated by the identification of CNS-associated macrophages (CAMs) as CNS interface residents, who, most likely, accompanied microglia in evolution over the past million years.作者: confide 時(shí)間: 2025-3-27 16:06
Progress in Structural and Functional In Vivo Imaging of Microglia and Their Application in Health arauma, or in neurodegenerative or neuroinflammatory diseases, microglial responses range from protective to harmful, underscoring the need to better understand their diverse roles and states in different pathological conditions. In this chapter, we introduce multiphoton microscopy and discuss recent作者: jarring 時(shí)間: 2025-3-27 20:50 作者: hypnogram 時(shí)間: 2025-3-27 23:26 作者: Omniscient 時(shí)間: 2025-3-28 04:56 作者: Concerto 時(shí)間: 2025-3-28 09:11 作者: 任意 時(shí)間: 2025-3-28 13:17 作者: 和平主義 時(shí)間: 2025-3-28 16:22
Jung-Seok Kim,Steffen Jungcoholism, depression, and suicide.?.?.The authors present interventions and measures for resilience training backed by research and demonstrated results within 978-3-319-38778-9978-3-319-38779-6Series ISSN 2193-6595 Series E-ISSN 2193-6609 作者: mastoid-bone 時(shí)間: 2025-3-28 20:42 作者: Outspoken 時(shí)間: 2025-3-29 02:14
Elena Guffart,Marco Prinz has evolved over the last half century, changing from “de-ruralisation” in the 1960s to “tertiarisation” starting in early 1980s. Initially, the development models avoided the centre of the metropolitan area, the focus being on the strongly industrialised outskirts. The tertiary sector revealed an 作者: receptors 時(shí)間: 2025-3-29 05:28 作者: 使腐爛 時(shí)間: 2025-3-29 09:13
Marcus Augusto-Oliveira,Marie-ève Tremblay,Alexei Verkhratskyto develop a conceptual model of resilience pertinent to homeless older adults. We offer a brief overview of existing conceptualizations of resilience, followed by a description of late-life resilience that focuses on cumulative adaptive capability across different temporal locations. Subsequently, 作者: 蘑菇 時(shí)間: 2025-3-29 12:47 作者: 痛苦一下 時(shí)間: 2025-3-29 19:38 作者: 分開(kāi)如此和諧 時(shí)間: 2025-3-29 21:54 作者: 上坡 時(shí)間: 2025-3-30 01:51
G. Jean Harryuld incorporate elements aimed at improving self esteem and increasing cultural identification despite past failures to demonstrate that they have a strong direct influence on drug use. But if resilience is to be included as an element in prevention, it must be remembered that the role played by res作者: 假設(shè) 時(shí)間: 2025-3-30 05:06
Haley A. Vecchiarelli,Luana Tenorio Lopes,Rosa C. Paolicelli,Beth Stevens,Hiroaki Wake,Marie-ève Tree, and a heretofore unparalleled level of cooperation among investigators, it would be possible to develop a large database of studies to conduct systematic meta-analyses. Such meta-analyses could be of enormous value in identifying common and unique risk and protective factors associated with the w作者: Needlework 時(shí)間: 2025-3-30 12:05 作者: neurologist 時(shí)間: 2025-3-30 12:30 作者: AXIS 時(shí)間: 2025-3-30 19:16
Linh Le,Kazuya Miyanishi,Junya Tanaka,Ania K. Majewskae, and a heretofore unparalleled level of cooperation among investigators, it would be possible to develop a large database of studies to conduct systematic meta-analyses. Such meta-analyses could be of enormous value in identifying common and unique risk and protective factors associated with the w
