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標(biāo)題: Titlebook: Microbial Resistance to Drugs; Lawrence E. Bryan (Head) Book 1989 Springer-Verlag Berlin Heidelberg 1989 antibiotic.antibiotics.genetics.m [打印本頁(yè)]

作者: Stubborn    時(shí)間: 2025-3-21 18:25
書(shū)目名稱(chēng)Microbial Resistance to Drugs影響因子(影響力)




書(shū)目名稱(chēng)Microbial Resistance to Drugs影響因子(影響力)學(xué)科排名




書(shū)目名稱(chēng)Microbial Resistance to Drugs網(wǎng)絡(luò)公開(kāi)度




書(shū)目名稱(chēng)Microbial Resistance to Drugs網(wǎng)絡(luò)公開(kāi)度學(xué)科排名




書(shū)目名稱(chēng)Microbial Resistance to Drugs被引頻次




書(shū)目名稱(chēng)Microbial Resistance to Drugs被引頻次學(xué)科排名




書(shū)目名稱(chēng)Microbial Resistance to Drugs年度引用




書(shū)目名稱(chēng)Microbial Resistance to Drugs年度引用學(xué)科排名




書(shū)目名稱(chēng)Microbial Resistance to Drugs讀者反饋




書(shū)目名稱(chēng)Microbial Resistance to Drugs讀者反饋學(xué)科排名





作者: 十字架    時(shí)間: 2025-3-21 23:34

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作者: CLAP    時(shí)間: 2025-3-22 04:59
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/m/image/633030.jpg
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https://doi.org/10.1007/978-3-642-74095-4antibiotic; antibiotics; genetics; methylation; microbes; resistance
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作者: musicologist    時(shí)間: 2025-3-22 20:50
Beta-Lactamases: Genetic Control,ere discovered as early as 1940, when an extract of a strain of . was shown to inactivate a solution of benzylpenicillin (. et al. 1940). A few years later the importance of beta-lactamases was demonstrated in gram-positive bacteria when . producing such an enzyme was shown to be responsible for clinical resistance to penicillin (. 1947).
作者: 沙漠    時(shí)間: 2025-3-22 22:12
Clinical Laboratory Testing for Antimicrobial Resistance,cal laboratory are still actively discussed, under development, or undergoing rapid change Browsing in the more than 1000 pages of . in its second edition (. 1986), one feels overwhelmed by the magnitude and complexity of the clinical laboratory aspects of antibiotics and chemotherapeutic agents.
作者: ADOPT    時(shí)間: 2025-3-23 05:17
Microbial Persistence or Phenotypic Adaptation to Antimicrobial Agents: Cystic Fibrosis as an IllusSuch changes are normally manifest mainly during the course of therapy but in some instances may be stable beyond its termination. Even in the latter circumstances when bacterial colonization continues, isolates expressing lower susceptibility are often replaced by more susceptible organisms.
作者: 淘氣    時(shí)間: 2025-3-23 09:34
L. E. Bryancollective PCK (cPCK) and pedagogical knowledge (PK). The analyses reveal a stronger correlation between PK and cPCK in the first half and stronger correlation between CK and cPCK in the second half of teacher education. Again from a RCM perspective, the second study used the same instrument to asse
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作者: 不再流行    時(shí)間: 2025-3-23 16:12
B. G. Sprattre we utilised the PCK map approach in different ways, while identifying and addressing methodological issues. Finally, we highlight the potential of the PCK map approach as a methodological tool to capture the essence of science teachers’ enacted PCK (ePCK) throughout the pedagogical cycle of plann
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作者: 內(nèi)疚    時(shí)間: 2025-3-24 05:30
S. Chamberland offer a researcher lens with examples from large-scale science PCK studies conducted in Germany and the USA. Each vignette follows a similar structure and includes these three parts:.As with any model, the true test of its power lies in its utility. Only by employing the RCM in a host of settings—t
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E. Cundliffel representation are normally discussed in a language which is slightly dated in character and tends to reflect the values of nineteenth-century liberalism. To overcome these limitations it is necessary for the student to disengage himself from the assumptions of liberal democracy and consider the i
作者: 大范圍流行    時(shí)間: 2025-3-24 22:46

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作者: 推遲    時(shí)間: 2025-3-25 09:12
D. M. Shlaes,C. A. Currie-McCumbertion learning presented can also benefit other related domains such as machine learning, socialnetwork analysis, semantic Web, information retrieval, data mining and computational biology. This book is intended for advanced undergraduate and graduate students, post-doctoral fellows, researchers, lec
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作者: 陶醉    時(shí)間: 2025-3-26 01:12

作者: 玉米    時(shí)間: 2025-3-26 04:41
Resistance to Quinolones and Fluoroquinolones,sition 6 of the quinolone nucleus (Fig. 1). This was found to enhance the antibacterial activity and enable adequate serum concentrations to be achieved (. and . 1985). Other substituents in addition to the fluorine have been added to the nucleus with the aim of increasing the anti-gram positive bac
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作者: Inkling    時(shí)間: 2025-3-26 15:42
Book 1989lly to an increasing extent in the future, such study has also contributed to advances in antimicrobial chemotherapy. Through- out the book resistance mechanisms have been placed in perspective as to their significance as causes of resistance to key drugs or groups of drugs. Some are of much greater
作者: 拒絕    時(shí)間: 2025-3-26 20:25
W. V. Shaw,A. G. W. Leslieht using selected examples and sample Python code. The monograph should be of interest to a wide audience, ranging from data scientists, machine learning researchers and students to developers, software engineers and industrial researchers interested in hands-on AI solutions.978-3-030-68819-6978-3-030-68817-2
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作者: 針葉類(lèi)的樹(shù)    時(shí)間: 2025-3-27 03:27
Role of the Outer Membrane of Gram-Negative Bacteria in Antimicrobial Resistance, extra membrane layer on the surface of these organisms: the outer membrane of these bacteria acts as an effective permeation barrier and retards the influx of antibiotic molecules into the bacterial cell.
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作者: 法律的瑕疵    時(shí)間: 2025-3-27 23:12
Plasmid-Determined Beta-Lactamases,elve plasmid-determined beta-lactamases are known so far to be encoded by transposons (Table 1), genetic elements that can transfer from one plasmid to another and to and from plasmids and the bacterial chromosome (. and . 1974).
作者: EWER    時(shí)間: 2025-3-28 03:52
Resistance to Sulfonamides,ailability of more active antibiotics and to the prevalence of resistance. Despite their age, however, they maintained importance as alternative drugs or — mostly in combination with dihydrofolate reductase inhibitors — as drugs of first choice for a variety of infections.
作者: prick-test    時(shí)間: 2025-3-28 06:27

作者: 巨頭    時(shí)間: 2025-3-28 12:18
The Molecular Epidemiology of Antimicrobial Resistance,cs, but especially of tetracyclines, broad spectrum penicillins and sulfamethoxazole-trimethoprim, are being used throughout the world (. and . 1987). In many countries, this usage is uncontrolled, and widespread underdosing from use of over-the-counter combinations obtained without prescription is the rule.
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Book 1989gents. Thus we tend to see discussion of resistance to f3-lactams, tetracyclines, amino- glycosides etc. In this book many of the authors were asked to emphasize the mechanism of resistance in their discussion and from that to show how susceptibility to various agents was affected. In part this was
作者: NAV    時(shí)間: 2025-3-29 07:06
Role of the Outer Membrane of Gram-Negative Bacteria in Antimicrobial Resistance, same time it produced an increase in infections, often hospital-acquired, by antibiotic-resistant gram-negative bacteria of moderate or even marginal pathogenicity (. 1985). The general resistance to antibiotics, often encountered in such gram-negative bacteria, is largely due to the presence of an
作者: 不規(guī)則    時(shí)間: 2025-3-29 08:01

作者: 賠償    時(shí)間: 2025-3-29 15:11
Resistance to ,-Lactam Antibiotics Mediated by Alterations of Penicillin-Binding Proteins, lipid-linked disaccharide-pentapeptide substrate of the enzymes that catalyse the synthesis of crosslinked peptidoglycan (. and . 1983). These enzymes can be detected and studied as penicillin-binding proteins (PBPs) as they are essentially irreversibly acylated by penicillin, and other .-lactam an
作者: 公共汽車(chē)    時(shí)間: 2025-3-29 16:41

作者: 哎呦    時(shí)間: 2025-3-29 20:02

作者: Armada    時(shí)間: 2025-3-30 02:31
Beta-Lactamases: Genetic Control,ere discovered as early as 1940, when an extract of a strain of . was shown to inactivate a solution of benzylpenicillin (. et al. 1940). A few years later the importance of beta-lactamases was demonstrated in gram-positive bacteria when . producing such an enzyme was shown to be responsible for cli
作者: Basilar-Artery    時(shí)間: 2025-3-30 05:32
Resistance to Quinolones and Fluoroquinolones,r agents nalidixic and oxolinic acid. The quinolone class (which includes 4-pyridone antibacterials) share the 4-quinolone nucleus and also a carboxylic acid substituent at position 3 (Fig. 1). During the last twenty-five years many compounds have been synthesised with additional substituents upon t
作者: 隱語(yǔ)    時(shí)間: 2025-3-30 09:43
Ribosomal Changes Resulting in Antimicrobial Resistance,soluble protein synthesis factors or at the ribosome. The response of susceptible cells to these compounds may be altered by mutational changes of the primary structure of some component of the translational system or by the enzymatic activity of a gene product which introduces a covalent modificati
作者: 全神貫注于    時(shí)間: 2025-3-30 13:56
Methylation of RNA and Resistance to Antibiotics,olecules may be physically prevented from encountering the target site(s) at which they normally act, either by direct exclusion at membrane barriers or by chemical inactivation due to extracellular enzymes (e.g. .-lactamases). In other instances, where total exclusion of the drug from the cytoplasm
作者: Pert敏捷    時(shí)間: 2025-3-30 20:23
Resistance to Trimethoprim,ounds possess both antimalarial and antibacterial activity, the former activity exemplified by pyrimethamine and the latter activity by trimethoprim (Tp). Tp is a potent inhibitor of dihydrofolate reductase (5,6,7,8-tetrahydrofolate: NADP. oxidoreductase EC 1.5.1.3; DHFR), an enzyme that catalyzes t
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作者: 領(lǐng)袖氣質(zhì)    時(shí)間: 2025-3-31 13:10
Clinical Laboratory Testing for Antimicrobial Resistance,cal laboratory are still actively discussed, under development, or undergoing rapid change Browsing in the more than 1000 pages of . in its second edition (. 1986), one feels overwhelmed by the magnitude and complexity of the clinical laboratory aspects of antibiotics and chemotherapeutic agents.
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