標(biāo)題: Titlebook: Microbial DNA and Host Immunity; Eyal Raz Book 2002 Springer Science+Business Media New York 2002 Antigen.Asthma.DNA.HIV.Nucleotide.infect [打印本頁] 作者: Disclose 時間: 2025-3-21 16:10
書目名稱Microbial DNA and Host Immunity影響因子(影響力)
書目名稱Microbial DNA and Host Immunity影響因子(影響力)學(xué)科排名
書目名稱Microbial DNA and Host Immunity網(wǎng)絡(luò)公開度
書目名稱Microbial DNA and Host Immunity網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Microbial DNA and Host Immunity被引頻次
書目名稱Microbial DNA and Host Immunity被引頻次學(xué)科排名
書目名稱Microbial DNA and Host Immunity年度引用
書目名稱Microbial DNA and Host Immunity年度引用學(xué)科排名
書目名稱Microbial DNA and Host Immunity讀者反饋
書目名稱Microbial DNA and Host Immunity讀者反饋學(xué)科排名
作者: 教育學(xué) 時間: 2025-3-21 21:57
Signal Transduction Pathways Activated By CpG-DNArrays of ODNs—there is a clear species specificity in respect to the sequences active in mouse vs humans. Hence, it might be speculated that double-stranded bacterial DNA represents a pool of various stimulatory sequences that are recognized by specific but species-dependent receptor systems. DNA th作者: 讓步 時間: 2025-3-22 02:51
A Novel Toll-Like Receptor that Recognizes Bacterial DNAn with leucine-rich repeats in the extracellular domain and a cytoplasmic Toll/interleukin (IL)-1 receptor homology (TIR) domain. So far, ten members of human TLR are identified (.). Biological functions of some TLR family members are revealed; TLR4 is responsible for the recognition of LPS and TLR2作者: 死亡率 時間: 2025-3-22 08:23
Phosphorothioate Backbone Modification Changes the Pattern of Responses to CpGy one of the nonbridging oxygens of the phosphate group is converted to sulfur. Phosphorothioates are poor substrates for most cellular nucleases. CpG PS-ODN display many of the activities of bacterial DNA, but owing to evidence of phosphorothioate-specific activity, caution has been urged in their 作者: colony 時間: 2025-3-22 08:59 作者: surrogate 時間: 2025-3-22 14:47 作者: condone 時間: 2025-3-22 19:51
Cross-Priming of CD8+ T Cells by Immunostimulatory Sequence DNAtitis B virus surface antigen (.), and human immunodeficiency virus gp 120 (.). Effective CTL and T. 1 priming has been observed with both intradermal (.) and intranasal (.) routes of immunization. Of note, priming of CTL activity with ISS-ODN and protein antigen, either coadministration or as conju作者: Directed 時間: 2025-3-22 23:31 作者: 突變 時間: 2025-3-23 01:45
Immunostimulatory DNA Sequence Based Mucosal Vaccinesstimulating protective mucosal immune responses. Live viral vaccines, such as the attenuated oral polio vaccine, induce strong mucosal immune responses. However, only a limited number of attenuated vaccines exist. The majority used in clinical practice are derived from recombinant proteins (.). Thes作者: 潛移默化 時間: 2025-3-23 08:23
inhibitors, tyrosine kinase inhibitors and mTOR inhibitors, for patients with advanced renal cell carcinoma...Renal Cell Cancer: Diagnosis and Therapy. is the reference work of choice on this topic for urologists and oncologists..978-1-4471-7123-2978-1-84628-763-3作者: 夾死提手勢 時間: 2025-3-23 09:48
inhibitors, tyrosine kinase inhibitors and mTOR inhibitors, for patients with advanced renal cell carcinoma...Renal Cell Cancer: Diagnosis and Therapy. is the reference work of choice on this topic for urologists and oncologists..978-1-4471-7123-2978-1-84628-763-3作者: Capitulate 時間: 2025-3-23 14:18
Eyal Razinhibitors, tyrosine kinase inhibitors and mTOR inhibitors, for patients with advanced renal cell carcinoma...Renal Cell Cancer: Diagnosis and Therapy. is the reference work of choice on this topic for urologists and oncologists..978-1-4471-7123-2978-1-84628-763-3作者: 強制令 時間: 2025-3-23 18:45 作者: 招惹 時間: 2025-3-24 02:05
inhibitors, tyrosine kinase inhibitors and mTOR inhibitors, for patients with advanced renal cell carcinoma...Renal Cell Cancer: Diagnosis and Therapy. is the reference work of choice on this topic for urologists and oncologists..978-1-4471-7123-2978-1-84628-763-3作者: Barter 時間: 2025-3-24 04:06 作者: 怪物 時間: 2025-3-24 06:44
Hiroaki Hemmi,Shizuo Akirainhibitors, tyrosine kinase inhibitors and mTOR inhibitors, for patients with advanced renal cell carcinoma...Renal Cell Cancer: Diagnosis and Therapy. is the reference work of choice on this topic for urologists and oncologists..978-1-4471-7123-2978-1-84628-763-3作者: Thyroid-Gland 時間: 2025-3-24 12:35 作者: BOOM 時間: 2025-3-24 17:44 作者: omnibus 時間: 2025-3-24 21:52 作者: Ischemic-Stroke 時間: 2025-3-25 02:26
Saburo Yamamoto,Toshiko Yamamoto,Tetsuro Kataoka,Sumiko Iho,Tohru Tokunagainhibitors, tyrosine kinase inhibitors and mTOR inhibitors, for patients with advanced renal cell carcinoma...Renal Cell Cancer: Diagnosis and Therapy. is the reference work of choice on this topic for urologists and oncologists..978-1-4471-7123-2978-1-84628-763-3作者: 講個故事逗他 時間: 2025-3-25 06:12 作者: Sciatica 時間: 2025-3-25 10:59
Ae-Kyung Yi,Arthur M. Krieginhibitors, tyrosine kinase inhibitors and mTOR inhibitors, for patients with advanced renal cell carcinoma...Renal Cell Cancer: Diagnosis and Therapy. is the reference work of choice on this topic for urologists and oncologists..978-1-4471-7123-2978-1-84628-763-3作者: champaign 時間: 2025-3-25 13:39 作者: Misnomer 時間: 2025-3-25 16:30 作者: 虛度 時間: 2025-3-25 23:40 作者: 凈禮 時間: 2025-3-26 00:19 作者: Cpr951 時間: 2025-3-26 04:26 作者: Insufficient 時間: 2025-3-26 10:19 作者: AXIOM 時間: 2025-3-26 14:33
Immunostimulatory DNAil constitutes Freund’s famous adjuvant (. Chapter 2) However, mycobacterial and other bacterial DNAs were shown to contribute to the adjuvanticity of this complex reagent only in the early 1980s. Tokunaga and coworkers discovered that DNA purified from Mycobacterium bovis bacillus Calmette-Guerin (作者: 花費 時間: 2025-3-26 19:35
2 Historical Perspectivesthe growth of various guinea pig and mouse tumors, and augmented natural killer (NK) cell activity and induced interferons (IFNs) from mouse spleen cells (.). Further, we found two remarkable facts that作者: 角斗士 時間: 2025-3-26 22:53 作者: 使服水土 時間: 2025-3-27 04:53 作者: 吞吞吐吐 時間: 2025-3-27 05:50
5 Activation of Innate Immunity by Microbial Nucleic Acids LPS), by the host via pattern recognition receptors (PRR; .). Two different recognition systems were established to explain the activation of innate immunity by microbial product. The first PRR is intracellular and utilizes the PKR to recognize dsRNA, an intermediate product during viral replicatio作者: 討好美人 時間: 2025-3-27 13:06
Phosphorothioate Backbone Modification Changes the Pattern of Responses to CpGicked by oligonucletides (ODN) (.), and this has been critical in establishing the sequence requirements for activation. Both native phosphodiester oligonucleotides and phosphorothioate-modified oligonucleotides (PO-ODN and PS-ODN) of various sequences can activate macrophages, dendritic cells, and 作者: Mercurial 時間: 2025-3-27 16:04 作者: 和音 時間: 2025-3-27 21:04
Regulation of Antigen Presenting Cell Function by CpG DNApeptidoglycan, bacterial lipopeptides, lipoteichoic acid, microbial polysaccharides (e.g., mannans) and CpG DNA motifs present in bacterial DNA (.). The immune system uses pattern recognition receptors like the toll-like receptors (TLRs) to recognize these bacterial components, and transduce signals作者: MAZE 時間: 2025-3-28 01:37
Activation of B cells by CpG Motifs in Bacterial DNAelies on the assistance of the innate immune defenses, such as dendritic cells, which must be activated in order to trigger optimal immune responses. These cells of the innate immune system lack such highly specific antigen receptors, instead relying on a set of “pattern recognition receptors” (PRRs作者: 創(chuàng)造性 時間: 2025-3-28 04:23
IFN-Dependent Pathways for Stimulation of Memory CD8+ Cellsese T cells rarely divide in normal unimmunized animals but mount intense TCR-dependent proliferative responses when confronted with specific foreign ligands, i.e., foreign peptides bound to major histocompatibility complex (MHC) molecules on specialized antigen-presenting cells (APC). After elimina作者: 最低點 時間: 2025-3-28 06:34
Cross-Priming of CD8+ T Cells by Immunostimulatory Sequence DNAtem such as phagocytes (macrophages and dendritic cells [DC]) and NK cells and upon B cells, promoting the expression of proinflammatory cytokines and surface molecules (.). They have little direct effect upon CD8. and CD4. T cells, yet animal models have shown that ISS-based vaccines promote two an作者: Radiation 時間: 2025-3-28 13:52
The Th1 Adjuvant Effect of Immunostimulatory (ISS) DNA Sequencester gene encoded by the plasmid injected into the muscle cell (.). Subsequent studies revealed that this form of gene transfer could result in a protective immune response to influenza (.). The basis of this response was in the generation of antigen specific cytotoxic T lymphocyte (CTL) and humoral 作者: Ablation 時間: 2025-3-28 15:53
Immunostimulatory DNA Prepriming for the Induction of Th1 and Prevention of Th2 Biased Immune Responhe production of type-1 cytokines such as IL-12, type 1 IFNs, and IFN-γ from antigen-presenting cells (APCs), B cells, and NK cells in an antigen independent manner (.). In addition to these effects, ISS-ODN has more recently been shown to increase the expression of various costimulatory molecules o作者: neologism 時間: 2025-3-28 20:50
Protein-Immunostimulatory DNA-Conjugatetural killer (NK) cells to secrete interferon-γ (IFN-γ). Over the last 10 yr, this finding has stimulated much research on the immunostimulatory properties of bacterial DNA. It was shown that bacterial immunostimulatory DNA sequences (ISS) consist of palindromic sequences of the motif purine-purine-作者: figment 時間: 2025-3-29 02:27
Immunostimulatory DNA Sequence Based Mucosal Vaccinestabolic by-products. This relatively permeable nature places unique constraints and requirements on the immunocytes, which protect mucosal surfaces, and makes these sites particularly susceptible to penetration by infectious agents. Despite the relative efficiency of the mucosal immune system in pre作者: 一起平行 時間: 2025-3-29 05:35
cancer ranging from diagnostics, cancer research, molecular.Renal Cell Cancer: Diagnosis and Therap.y covers diagnostics, cancer research, molecular biology, immunology and clinical management. It provides an overview of new information in epidemiology, molecular and immunologic characteristics, an作者: foppish 時間: 2025-3-29 08:14
cancer ranging from diagnostics, cancer research, molecular.Renal Cell Cancer: Diagnosis and Therap.y covers diagnostics, cancer research, molecular biology, immunology and clinical management. It provides an overview of new information in epidemiology, molecular and immunologic characteristics, an作者: GIST 時間: 2025-3-29 14:40
Eyal Raz cancer ranging from diagnostics, cancer research, molecular.Renal Cell Cancer: Diagnosis and Therap.y covers diagnostics, cancer research, molecular biology, immunology and clinical management. It provides an overview of new information in epidemiology, molecular and immunologic characteristics, an作者: MAG 時間: 2025-3-29 17:55
Saburo Yamamoto,Toshiko Yamamoto,Tohru Tokunaga cancer ranging from diagnostics, cancer research, molecular.Renal Cell Cancer: Diagnosis and Therap.y covers diagnostics, cancer research, molecular biology, immunology and clinical management. It provides an overview of new information in epidemiology, molecular and immunologic characteristics, an作者: 黑豹 時間: 2025-3-29 22:39
cancer ranging from diagnostics, cancer research, molecular.Renal Cell Cancer: Diagnosis and Therap.y covers diagnostics, cancer research, molecular biology, immunology and clinical management. It provides an overview of new information in epidemiology, molecular and immunologic characteristics, an作者: optional 時間: 2025-3-30 03:42
Hans H?cker cancer ranging from diagnostics, cancer research, molecular.Renal Cell Cancer: Diagnosis and Therap.y covers diagnostics, cancer research, molecular biology, immunology and clinical management. It provides an overview of new information in epidemiology, molecular and immunologic characteristics, an作者: NATAL 時間: 2025-3-30 06:01 作者: Mawkish 時間: 2025-3-30 09:39
Wen-Ming Chu,Xing Gong,Tony Yoon cancer ranging from diagnostics, cancer research, molecular.Renal Cell Cancer: Diagnosis and Therap.y covers diagnostics, cancer research, molecular biology, immunology and clinical management. It provides an overview of new information in epidemiology, molecular and immunologic characteristics, an作者: Exterior 時間: 2025-3-30 14:39 作者: Ingenuity 時間: 2025-3-30 20:09 作者: 演講 時間: 2025-3-31 00:12