作者: LAVA 時(shí)間: 2025-3-21 22:02
978-3-030-33310-2Springer Nature Switzerland AG 2020作者: Morose 時(shí)間: 2025-3-22 03:21
http://image.papertrans.cn/m/image/632928.jpg作者: Enrage 時(shí)間: 2025-3-22 06:59
https://doi.org/10.1007/978-3-030-33308-9Microbiology; second messengers; cyclic di-GMP; cyclic GAMP; cyclic di-AMP; 2’3 cyclic AMP; biofilm format作者: 裁決 時(shí)間: 2025-3-22 11:04 作者: 蛛絲 時(shí)間: 2025-3-22 13:21 作者: 靈敏 時(shí)間: 2025-3-22 19:59 作者: 充足 時(shí)間: 2025-3-22 23:06 作者: 屈尊 時(shí)間: 2025-3-23 03:20
Insights into the Molecular Basis of Biofilm Dispersal from Crystal Structures of Didomain Containinbeen spent to understand its molecular basis. Bis-(3′5′)-cyclic dimeric guanosine monophosphate (cyclic di-GMP) is a second messenger involved in the regulation of bacterial motility, virulence, and biofilm formation. The amount of cyclic di-GMP results from the balance between its synthesis from GT作者: 濕潤(rùn) 時(shí)間: 2025-3-23 09:07 作者: ASSET 時(shí)間: 2025-3-23 12:15 作者: 誘使 時(shí)間: 2025-3-23 14:37 作者: eulogize 時(shí)間: 2025-3-23 19:15
Detection of Cyclic Dinucleotide Binding Proteins In response to stimuli, activated dinucleotide cyclases synthesize cyclic dinucleotides. Once made, cyclic dinucleotides bind macromolecule receptors, including proteins and RNA, to allosterically regulate downstream functions. Many important classes of cyclic di-GMP protein receptors have been ide作者: 多余 時(shí)間: 2025-3-24 00:26 作者: Mercantile 時(shí)間: 2025-3-24 04:01 作者: 小口啜飲 時(shí)間: 2025-3-24 09:08 作者: garrulous 時(shí)間: 2025-3-24 14:36
Osmoregulation via Cyclic di-AMP Signalingriboswitch receptors. Cyclic di-AMP has been found to impact on a wide array of cellular processes including resistance to acid, heat, antibiotics, osmolarity changes and connected to central metabolism, peptidoglycan homeostasis, virulence, biofilm formation, immunomodulation, sporulation, DNA repa作者: 注入 時(shí)間: 2025-3-24 18:06
Measuring Individual Cell Cyclic di-GMP: Identifying Population Diversity and Cyclic di-GMP Heteroges in the measurement of real time cyclic di-GMP levels in single cells have uncovered significant dynamic heterogeneity of second messenger concentrations within bacterial populations. This heterogeneity results in a wide range of phenotypic outcomes within a single population, providing the potenti作者: saturated-fat 時(shí)間: 2025-3-24 22:59 作者: 使入迷 時(shí)間: 2025-3-25 00:43
tide turnover proteins and receptors.Reports on the populati.This book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical char作者: Parabola 時(shí)間: 2025-3-25 03:33 作者: 清晰 時(shí)間: 2025-3-25 10:42 作者: 是比賽 時(shí)間: 2025-3-25 13:39
Noncanonical Cyclic?di-GMP Binding ModesGDEF motif without an inhibitory site; (2) a PilZ domain structure that is interrupted in the middle by two long helices and self-assembles into a tetramer via the leucine-rich heptad repeat; and (3) a new bulge conformation of cyclic di-GMP with one guanine base flipping from . to . in binding to a degenerate EAL domain.作者: 盤旋 時(shí)間: 2025-3-25 18:27
bacillus.?are among the representatives of the microbial kingdom that are described..In turn, the various aspects of bacterial physiology affected by these signaling systems– e.g. biofilm formation and dispersa978-3-030-33310-2978-3-030-33308-9作者: 遠(yuǎn)足 時(shí)間: 2025-3-25 23:38
Anushya Petchiappan,Avisek Mahapa,Dipankar Chatterji作者: 上下連貫 時(shí)間: 2025-3-26 02:59 作者: 相一致 時(shí)間: 2025-3-26 08:15
Serena Rinaldo,Alessandro Paiardini,Alessio Paone,Francesca Cutruzzolà,Giorgio Giardina作者: Myocarditis 時(shí)間: 2025-3-26 09:56 作者: inscribe 時(shí)間: 2025-3-26 16:39 作者: 大方不好 時(shí)間: 2025-3-26 20:43 作者: Favorable 時(shí)間: 2025-3-26 21:11
Structure and Regulation of EAL Domain Proteinsgulation and has provided novel insight into the enzymatic reaction mechanism. Several regulatory layers may control activity, including dimerisation, active site formation, and metal coordination. In this review, we provide a concise summary of these exciting findings and highlight open research qu作者: 出血 時(shí)間: 2025-3-27 03:57 作者: 軟弱 時(shí)間: 2025-3-27 07:24
Structure and Function of HD-GYP Phosphodiesterasesred into two distinct groups depending on the metal binding site, which can accommodate two or three metal ions. The nature and the number of bound metals determine whether a certain HD-GYP will be active as a PDE or will function as a dinucleotide binding domain. In this chapter, we will review the作者: LOPE 時(shí)間: 2025-3-27 13:13
A Unified Catalytic Mechanism for Cyclic di-NMP Hydrolysis by DHH–DHHA1 Phosphodiesterasesears. According to detailed structural and enzymatic analyses, we have summarized a unified molecular mechanism for the DHH–DHHA1 PDEs and systematically analyzed the catalytic activities of DHH–DHHA1 PDEs on other cyclic di-NMPs (cyclic di-GMP and cGAMP).作者: 切割 時(shí)間: 2025-3-27 15:09 作者: 固執(zhí)點(diǎn)好 時(shí)間: 2025-3-27 21:50
Detection of Cyclic Dinucleotide Binding Proteinss, the field has revealed that cyclic di-GMP directly regulates many cellular functions through allosteric binding. Despite the success in the field of identifying protein receptors in the past few decades, cyclic dinucleotide receptors often can only be experimentally identified due to their divers作者: Silent-Ischemia 時(shí)間: 2025-3-27 23:11 作者: 生存環(huán)境 時(shí)間: 2025-3-28 02:30
Metabolic Regulation by Cyclic di-AMP Signalingonal levels, as well as the molecular mechanism of this regulation. We will highlight the regulation of central carbon metabolism through pyruvate carboxylase, the regulation of cell wall metabolism through the . riboswitch, and the impact on host cell inflammatory response through competitive inhib作者: synchronous 時(shí)間: 2025-3-28 09:59 作者: Transfusion 時(shí)間: 2025-3-28 14:04
Activation of Bacterial Cellulose Biosynthesis by Cyclic di-GMPtructural and functional characterizations of . cellulose synthase in resting and activated states provided unique insights into how cyclic di-GMP modulates enzymatic functions. This will be reviewed by discussing (1) biochemical analyses leading to cyclic di-GMP’s discovery and elucidation of its a作者: 違抗 時(shí)間: 2025-3-28 16:04 作者: 吞吞吐吐 時(shí)間: 2025-3-28 20:53 作者: 職業(yè) 時(shí)間: 2025-3-29 02:07 作者: 行業(yè) 時(shí)間: 2025-3-29 04:33 作者: jealousy 時(shí)間: 2025-3-29 11:19
deriving value-added products from biomass waste.Provides a.This volume discusses the reduction, recycling, and reuse of industrial and agricultural biomass wastes to develop value-added products using environmentally sustainable practices and technologies. Through these waste valorization approach作者: oblique 時(shí)間: 2025-3-29 12:31 作者: athlete’s-foot 時(shí)間: 2025-3-29 17:58
,Rechtsschutz gegen polizeiliche und ordnungsbeh?rdliche Ma?nahmen,es gegen polizeiliche und ordnungsbeh?rdliche Ma?nahmen dient dem Schutz der individuellen Rechtspositionen des Einzelnen. Dem haben Konstruktionen und Interpretationen der prozessualen Mechanismen Rechnung zu tragen.作者: 形容詞詞尾 時(shí)間: 2025-3-29 21:39 作者: 善變 時(shí)間: 2025-3-30 03:00
Hans Kind vornen aber auff gedachte ga? stossend? für 800 Gulden.. Die Formulierung ?Hausplatz? und die vergleichsweise niedrige Kaufsumme in H?he von 800 Gulden lassen vermuten, da? es sich urn ein noch nicht wieder bebautes Grundsrtück handelt. über Beginn und Vollendung des von Coblitz errichteten, barock作者: Antecedent 時(shí)間: 2025-3-30 06:43 作者: Vasoconstrictor 時(shí)間: 2025-3-30 08:31
Aleksandr Smirnov,Lev Dobshits,Sergey Anisimov, Beijing Academy of Agricultural and Forestry Sciences, etc. have greatly contributed and supported to this event. The conference is as good platform to bring together scientists and researchers, agronomists a978-1-4419-5493-0978-1-4419-0209-2Series ISSN 1868-4238 Series E-ISSN 1868-422X 作者: 暴發(fā)戶 時(shí)間: 2025-3-30 15:10 作者: 尾隨 時(shí)間: 2025-3-30 17:44 作者: 導(dǎo)師 時(shí)間: 2025-3-30 22:53