標(biāo)題: Titlebook: MicroRNA Targeted Cancer Therapy; Fazlul H. Sarkar Book 2014 Springer International Publishing Switzerland 2014 Cancer Therapy.Drug Resist [打印本頁] 作者: 落后的煤渣 時間: 2025-3-21 16:25
書目名稱MicroRNA Targeted Cancer Therapy影響因子(影響力)
書目名稱MicroRNA Targeted Cancer Therapy影響因子(影響力)學(xué)科排名
書目名稱MicroRNA Targeted Cancer Therapy網(wǎng)絡(luò)公開度
書目名稱MicroRNA Targeted Cancer Therapy網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱MicroRNA Targeted Cancer Therapy被引頻次
書目名稱MicroRNA Targeted Cancer Therapy被引頻次學(xué)科排名
書目名稱MicroRNA Targeted Cancer Therapy年度引用
書目名稱MicroRNA Targeted Cancer Therapy年度引用學(xué)科排名
書目名稱MicroRNA Targeted Cancer Therapy讀者反饋
書目名稱MicroRNA Targeted Cancer Therapy讀者反饋學(xué)科排名
作者: 植物群 時間: 2025-3-21 22:38
miRNA Expression and Functions in Glioma and Glioma Stem Cells,Unfortunately, prognosis remains extremely poor and the median survival of 12–14 months in GBM has not changed significantly. GBMs contain a small subpopulation of glioma stem cells (GSCs) that are implicated in therapeutic resistance and tumor recurrence. Thus, the development of new therapeutic st作者: 合法 時間: 2025-3-22 01:49
The Role of MicroRNA in Lung Cancer Drug Resistance and Targeted Therapy,motherapeutants to lung cancer cells is the primary issue during the chemotherapy of lung cancer. Many mechanisms such as the changes of drug metabolism related genes and signal pathways are involved in the chemoresistance. MicroRNAs (miRNAs) are a class of endogenetic, non-coding, short-chain and s作者: Asymptomatic 時間: 2025-3-22 07:36
The Potential Role of MicroRNA-Based Therapy for Lung Cancer Stem Cells, are strongly needed. Increasing evidence indicates that lung cancer stem cells (CSCs) are a therapeutic target for lung cancer. The CSC hypothesis is based on the simple concept that cancers contain a similar hierarchy with respect to self-renewal, differentiation and innate therapy resistance. Inv作者: Myocarditis 時間: 2025-3-22 10:35 作者: 酷熱 時間: 2025-3-22 14:19 作者: slipped-disk 時間: 2025-3-22 19:53
Application of MicroRNA in the Treatment and Diagnosis of Cervical Cancer,berrant miRNA expression is implicated in carcinogenesis and malignancy of cancer. miRNAs involved in carcinogenesis are broadly classified into oncogenic and tumor suppressor miRNAs, and overexpression of oncogenic miRNAs and decreased expression of tumor suppressor miRNAs are found in cancer cells作者: FAR 時間: 2025-3-22 23:34
Overcoming Drug Resistance in Colorectal Cancer by MicroRNAs,he expression of target genes by cleaving mRNA or through translation repression. As critical gene regulators, microRNAs modulate a variety of cellular events that among others include growth, differentiation and apoptosis. The microRNAs cause cancerous diversity and complexity. Based on microRNA’s 作者: incarcerate 時間: 2025-3-23 02:31
MicroRNAs as Novel Targets in Liver Cancer: Facing the Clinical Challenge,d by a phenotypic and molecular heterogeneity that limits therapeutic progress. MicroRNAs play a major role for the pathogenesis and progression of liver cancer. As an essential part of the RNA interference machinery, microRNAs contribute to the regulation of many pro-oncogenic processes in HCC, inc作者: seduce 時間: 2025-3-23 07:18
MicroRNA Based Therapeutic Strategies for Cancer: Emphasis on Advances in Renal Cell Carcinoma,, target prediction, biochemical tools and techniques to modulate miRNA activity, and the emergence of miRNA-centric animal models. One important conclusion that has emerged from this effort is that many microRNAs and their cognate targets are strongly implicated in cancer, either as oncogenes or tu作者: 高射炮 時間: 2025-3-23 13:07
Modulating MicroRNA Expression for the Therapy of Pancreatic Cancer,ients. Consequently, it is necessary to identify new therapeutic targets such as microRNAs to help manage this disease. Interestingly, these short non-coding RNAs can negatively control the expression of hundreds of genes, and thus are key regulators of tumor progression and dissemination. In additi作者: DEMUR 時間: 2025-3-23 17:55
MicroRNA Targeted Therapy for Overcoming Drug Resistance, Reversal of EMT and Elimination of Cancer transition (EMT) and cancer stem cells (CSCs) characteristics. Several miRNAs including let-7, miR-15/16, miR-200, miR-34a, miR-143/145, miR-21, miR-155, miR-197, and miR-221/222 have been found to play crucial roles in the control of drug resistance, EMT, and CSCs in pancreatic and prostate cancer作者: 變形詞 時間: 2025-3-23 18:30 作者: Fibroid 時間: 2025-3-24 02:04
miRNA-Targeted Therapies in the Most Prevalent Pediatric Solid Tumors,mors are mostly of epithelial origin and linked to a sustained exposure to environmental carcinogenic agents, pediatric malignancies tend to be of hematologic, mesenchymal or nervous system origin and their etiology is often unknown. Despite the small number of cases of childhood versus adult cancer作者: Lobotomy 時間: 2025-3-24 05:41 作者: 仔細(xì)檢查 時間: 2025-3-24 08:27
miRNA Regulation of DNA Damage Repair Proteins in Cancer Cells: Interplay of ATM, TRAIL and miRNA,chanisms. There are visible knowledge gaps related to current comprehensions about protein network that ultimately regulates decisions of DNA damage repair and apoptosis. Although evidence, in general, is sparse and fragmentary, merging knowledge links TRAIL mediated signaling, DNA damage repair and作者: 妨礙議事 時間: 2025-3-24 13:51 作者: MAUVE 時間: 2025-3-24 16:22
Systems Biology Approaches in the Design of Effective miRNA-Targeted Therapeutics,r sites of target mRNAs. A number of miRNAs have been recognized to be aberrantly expressed in cancer. These findings have led researchers to aggressively pursue miRNAs for cancer diagnostic and therapeutics. However, both identification and targeting of miRNAs is not very straight forward because e作者: Cardioplegia 時間: 2025-3-24 19:24 作者: 正常 時間: 2025-3-25 01:08
Sanila H. Sarkar,Aamir Ahmad,Sandeep Mittalin order to allow a safe operation of the train traffic. Interlockings are controlled by a software logic that relies on a generic software and a set of application data particular to the station under control. The verification of the application data is time consuming and error prone as it is mostl作者: 有發(fā)明天才 時間: 2025-3-25 03:56
Chaya Brodie,Efrat Buchris,Hae Kyung Leeesigns of realistic “real-world” complexity is possible and ready for industrial application. In this paper, we present a new model-based testing strategy for interlocking system controllers that exploits the fact that the design has already been verified, so that it can be used as a reference model作者: Fatten 時間: 2025-3-25 07:57
Zhaohui Gong,Zhuo Dong,Lihua Yang,Jie Yang,Jingqiu Li,Yanping Le,Shaomin Wang,Meng Ye,Hui-Kuan Linleader- ship from the top, good management practices, effective and efficient operation and maintenance systems, and use of appropriate up-to-date engineering de- sign tools and methods. Furthermore, manufacturing yield and reliability are interrelated. Manufacturing yield depends on the number of d作者: prosthesis 時間: 2025-3-25 13:55 作者: 翅膀拍動 時間: 2025-3-25 19:41 作者: sterilization 時間: 2025-3-25 21:36
Rong Guo,Cheryl Sherman-Baust,Kotb Abdelmohsenughout the world. Numerous organizations are involved in the development of national or regional cades without the benefit of interchange of ideas and methodologies. Harmonization and coordination of these activities is absolutely essential if the ever-increasing international commerce is to flouris作者: Antagonism 時間: 2025-3-26 00:08
Kouji Banno,Miho Iida,Megumi Yanokura,Iori Kisu,Kanako Nakamura,Masataka Adachi,Takashi Iwata,Kyoko design parameters of a component together to form a limit state function for mechanical design. This design methodology uses the reliability to replace the factor of safety as a measure of the safe status of a component. The goal of this methodology is to design a mechanical component with required作者: 狗窩 時間: 2025-3-26 05:51
Yingjie Yu,Pratima Nangia-Makker,Adhip P. N. Majumdaro link all design parameters of a component together to form a limit state function for mechanical design. This design methodology uses the reliability to replace the factor of safety as a measure of the safe status of a component. The goal of this methodology is to design a mechanical component wit作者: 令人苦惱 時間: 2025-3-26 08:35
Jens U. Marquardt,Peter R. Galleo link all design parameters of a component together to form a limit state function for mechanical design. This design methodology uses the reliability to replace the factor of safety as a measure of the safe status of a component. The goal of this methodology is to design a mechanical component wit作者: 燈絲 時間: 2025-3-26 15:22
Shahana Majid,Rajvir Dahiya design parameters of a component together to form a limit state function for mechanical design. This design methodology uses the reliability to replace the factor of safety as a measure of the safe status of a component. The goal of this methodology is to design a mechanical component with required作者: prosperity 時間: 2025-3-26 19:45
Marion Gayral,Yannick Delpu,Jér?me Torrisani,Pierre Cordelier design parameters of a component together to form a limit state function for mechanical design. This design methodology uses the reliability to replace the factor of safety as a measure of the safe status of a component. The goal of this methodology is to design a mechanical component with required作者: 痛苦一生 時間: 2025-3-26 21:20
Yiwei Li,Dejuan Kong,Aamir Ahmad,Bin Bao,Fazlul H. Sarkar design parameters of a component together to form a limit state function for mechanical design. This design methodology uses the reliability to replace the factor of safety as a measure of the safe status of a component. The goal of this methodology is to design a mechanical component with required作者: inhumane 時間: 2025-3-27 01:31
Cesar Seigi Fuziwara,Edna Teruko Kimura design parameters of a component together to form a limit state function for mechanical design. This design methodology uses the reliability to replace the factor of safety as a measure of the safe status of a component. The goal of this methodology is to design a mechanical component with required作者: Opponent 時間: 2025-3-27 05:50 作者: 豐富 時間: 2025-3-27 09:36 作者: formula 時間: 2025-3-27 17:33 作者: 釋放 時間: 2025-3-27 21:25 作者: Infant 時間: 2025-3-27 22:09 作者: 創(chuàng)造性 時間: 2025-3-28 03:36
o the system maintenance planning and implementation process. The essential life-cycle reliability centered maintenance (ReM) activities are focused on maintenance planning and the prevention of failure. The premise is that more efficient, and therefore effective, life-cycle main- tenance programs c作者: 和平主義 時間: 2025-3-28 07:26
oing PhD research project. The system prototype is expected to be capable of relaying advice to a traffic controller with the goal of minimising the effects of a disruption as much as possible and to potentially avoid future disruptions, for which accurate train movement and delay predictions using 作者: 危機(jī) 時間: 2025-3-28 12:56 作者: Verify 時間: 2025-3-28 14:54 作者: 愛了嗎 時間: 2025-3-28 18:47 作者: 模范 時間: 2025-3-28 22:57
Yu Fujita,Kazuyoshi Kuwano,Takahiro Ochiyamicroelectronics. Such an agenda should include: ? the economic impact of employing the microelectronics fabricated by in- dustry, ? a study of the relationship between reliability and yield, ? the progression toward miniaturization and higher reliability, and ? the correctness and complexity of new作者: 他姓手中拿著 時間: 2025-3-29 03:40
Kouji Banno,Miho Iida,Megumi Yanokura,Iori Kisu,Kanako Nakamura,Masataka Adachi,Takashi Iwata,Kyoko cess and the fundamental reliability mathematics. Then, the book presents several computational methods for calculating the reliability of a component under loads when its limit state function is established. Finally, the book presents how to establish the limit state functions of a component under 作者: 巡回 時間: 2025-3-29 08:11
Shahana Majid,Rajvir Dahiyacess and the fundamental reliability mathematics. Then, the book presents several computational methods for calculating the reliability of a component under loads when its limit state function is established. Finally, the book presents how to establish the limit state functions of a component under 作者: 騷擾 時間: 2025-3-29 11:51 作者: 軍械庫 時間: 2025-3-29 18:38
Yiwei Li,Dejuan Kong,Aamir Ahmad,Bin Bao,Fazlul H. Sarkarcess and the fundamental reliability mathematics. Then, the book presents several computational methods for calculating the reliability of a component under loads when its limit state function is established. Finally, the book presents how to establish the limit state functions of a component under 作者: Climate 時間: 2025-3-29 23:01 作者: 有斑點(diǎn) 時間: 2025-3-30 01:30 作者: 詳細(xì)目錄 時間: 2025-3-30 06:58 作者: puzzle 時間: 2025-3-30 08:59 作者: 有抱負(fù)者 時間: 2025-3-30 14:24
Ramzi M. Mohammad,B. Bao,Fazlul H. Sarkar,Philip A. Philip,Asfar S. Azmied on the potential of floating offshore wind technology and the challenges towards the next generation of floating offshore wind turbines, the objectives of this thesis are defined. The single steps for achieving these objectives—building the structure of the thesis—are outlined, and the publicatio作者: 事與愿違 時間: 2025-3-30 17:11
nts of a complete ReM program (which are applicable to any complex system or component and are not limited only to the aircraft industry). They describe special methodologies for improving the maintenance process. These include an on-condition maintenance (OeM) methodology to identify defects and po作者: PAN 時間: 2025-3-31 00:41 作者: instulate 時間: 2025-3-31 00:56
miRNA Expression and Functions in Glioma and Glioma Stem Cells,ince the clinical use of miRNAs is hindered by lack of effective delivery mechanisms to tumor sites, a particular focus is placed on the possible modes of delivery of miRNA mimics or antagonists focusing on viral vectors, nanoparticles, exosomes and stem cells.作者: Endearing 時間: 2025-3-31 05:32
The Potential Role of MicroRNA-Based Therapy for Lung Cancer Stem Cells,rious critical cellular processes such as proliferation, cell cycle progression, apoptosis and differentiation. Recent studies have shown that several miRNAs with critical roles in normal stem cell functions during development are important regulators of CSCs. Emerging evidence also illustrates that作者: ANTE 時間: 2025-3-31 10:59
Overcoming Drug Resistance in Colorectal Cancer by MicroRNAs, discussed, since these miRNAs play a critical role in devolvement of resistance to chemotherapeutics in colorectal cancer by regulating cancer stem cell (CSC) growth and differentiation. Further, we have briefly described current miRNA-based therapeutic strategies. In conclusion, miRNAs and mRNA re作者: Amenable 時間: 2025-3-31 15:13
MicroRNAs as Novel Targets in Liver Cancer: Facing the Clinical Challenge,uss the impact of microRNAs for the plasticity and phenotypic characteristics of hepatoma cells as well as for putative liver cancer stem cells. Further, we will review progress in high-throughput technologies as novel tools to identify patterns of deregulated microRNAs for diagnostic and prognostic作者: Acclaim 時間: 2025-3-31 18:36 作者: hair-bulb 時間: 2025-3-31 21:41
Modulation of Deregulated MicroRNAs for Target Therapy in Thyroid Cancer,t to develop an innovative molecular therapy to improve the available thyroid cancer therapies. MicroRNAs (.) are small endogenous non-coding RNAs (~22 nt) that act in the post-transcriptional regulation of mRNA levels through binding to mRNA 3′-untranslated region. Since . deregulation is a feature作者: 令人不快 時間: 2025-4-1 05:26
miRNA-Targeted Therapies in the Most Prevalent Pediatric Solid Tumors,essenger RNAs in a sequence-specific manner. In recent years, miRNAs have been found to be deregulated in a number of adult and pediatric malignancies and their restoration opens up an attractive new therapeutic approach. This chapter will review the discovery of miRNAs that can be therapeutic targe作者: Atmosphere 時間: 2025-4-1 09:51 作者: glowing 時間: 2025-4-1 13:28
Book 2014l non-coding RNAs could also regulate the expression of genes and likewise, miRNA genes are also regulated by transcription factors. The most attractive feature of miRNAs is that one miRNA can regulate many target genes (mRNAs) and thus miRNA targeted therapy is highly promising because multiple gen
