派博傳思國際中心

標(biāo)題: Titlebook: Methodology of the Evaluation of Psychotropic Drugs; Otto Benkert,Wolfgang Maier,Karl Rickels Conference proceedings 1990 Springer-Verlag [打印本頁]

作者: 乳缽    時(shí)間: 2025-3-21 17:28
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作者: 淺灘    時(shí)間: 2025-3-21 20:30
Testing the Efficacy of New Neuroleptic Drugsradically different pharmacological properties from those antipsychotic drugs currently available. Some of these compounds lack the rapid sedative action which characterises existing neuroleptics, and the clinical psychopharmacologist faces a real problem in evaluating the antipsychotic efficacy of
作者: 繼承人    時(shí)間: 2025-3-22 00:24

作者: 聾子    時(shí)間: 2025-3-22 04:34
Testing the Efficacy of New Hypnotic Drugs insomnia and 12.5% demonstrate insomnia severe enough to warrant medical help (Lugaresi et al. 1987; Bixler et al. 1979). This indicates the urgency of developing adequate methods of treatment. Benzodiazepines prevail in current insomnia therapy because of their relatively safe and prompt sleep-ind
作者: 流動(dòng)才波動(dòng)    時(shí)間: 2025-3-22 11:06
Placebo-Controlled Studies in Depression: Necessity and Feasibilityeach specific situation to evolve and be refined, and further developments continue to occur. Comparison of a new antidepressant with a placebo is required before acceptance by most of the major national regulatory authorities, particularly the FDA, but is still questioned by some clinicians more th
作者: Pepsin    時(shí)間: 2025-3-22 16:14

作者: 沖擊力    時(shí)間: 2025-3-22 19:01
Statistical Issues: Sample Size and Dropout, for many of the most common mental disorders. That has caused an evolutionary saltus in the kinds of research designs contemplated for studying the efficacy of compounds. Because of the need to compare the new treatment with the standard, studies with at least two “active” treatment conditions hav
作者: 猛擊    時(shí)間: 2025-3-22 22:55

作者: shrill    時(shí)間: 2025-3-23 04:08

作者: Infect    時(shí)間: 2025-3-23 09:27
Ascertainment of Side Effects in Psychopharmacologic Clinical Trialshe efficacy of proposed therapeutic agents. This has come about for a variety of reasons including the amendment to the U.S. Food, Drug, and Cosmetics Law in 1962 that requires proof of efficacy before marketing of prescription medications is permitted. Assessment or proof of safety prior to marketi
作者: V切開    時(shí)間: 2025-3-23 13:36

作者: 杠桿支點(diǎn)    時(shí)間: 2025-3-23 16:21
Functional Classification and Response to Psychotropic Drugsally useful psychopharmacological agents. Therefore, the success of research in drug evaluation strongly depends on the conceptual frameworks of diagnostic classification and how these change. For instance, at the beginning of the era of antidepressants 30 years ago, the efficacy of antidepressants
作者: sigmoid-colon    時(shí)間: 2025-3-23 20:30
National and International Guidelines for the Conduct of Clinical Trials of Psychotropic Drugsd. Belonging to this self-perpetuating community of so-called experts, whose fate is to spend hundreds of hours in national and international committees in developing various kinds of “guidelines”, one often wonders, whether there is really any practical impact of all these activities. It strikes me
作者: Arrhythmia    時(shí)間: 2025-3-24 01:27

作者: 發(fā)芽    時(shí)間: 2025-3-24 02:59

作者: glans-penis    時(shí)間: 2025-3-24 09:16

作者: aqueduct    時(shí)間: 2025-3-24 13:50
S. R. Hirsch,T. R. E. Barnesigion. Extrapolating from personal discussions with Professor Scheffler, various of his books, articles, and other unpublished materials authored and kindly provided by him, I contend that he adumbrates a post-empiricist rendering of religious belief which masterfully avoids some philosophical probl
作者: 我的巨大    時(shí)間: 2025-3-24 18:28
T. H. Crook,B. A. Johnson,G. J. Larrabeeen dominant throughout the history of philosophy, but in recent years the development of philosophical naturalism has diminished its prestige. Naturalism holds that reason’s putative grasp of these truths can either be explained away in terms of convention or dismissed entirely. The first move expla
作者: Dna262    時(shí)間: 2025-3-24 19:04

作者: circumvent    時(shí)間: 2025-3-25 01:04
P. Lavoris verbal strategies that focus on spatial design and spatial consciousness of writers and readers. More and more in our everyday work, play, and fervors—aside from the drama of “outer” space—we can read meticulous arguments about sites, movement across borders and edges, tourism, mapping, netting an
作者: 原來    時(shí)間: 2025-3-25 06:14

作者: 缺乏    時(shí)間: 2025-3-25 09:31
P. Becheaning than that of the infallibility of the consequence when the reason is posited. Accordingly every necessity is .; absolute, i.e. unconditioned, necessity therefore is a .. For . can never mean anything but to result from a given reason.’ These words are taken from the beginning of section 49 of
作者: 期滿    時(shí)間: 2025-3-25 14:50

作者: 半球    時(shí)間: 2025-3-25 16:20
traditional principles and at their inherent determinations and basic problems, while heeding every indi- cation of a transition to something new, in order to be critically open for all attempts at "another beginning. " A philosophizing which thus sees its proper place "between" tradition and anothe
作者: Gorilla    時(shí)間: 2025-3-25 20:26

作者: Expand    時(shí)間: 2025-3-26 01:44

作者: fructose    時(shí)間: 2025-3-26 05:47

作者: fidelity    時(shí)間: 2025-3-26 11:21
B. Müller-Oerlinghausenir explanations. Those views have, over the course of the history of science, become increasingly coherent, in the sense both of constituting a more and more unified perspective on a larger and larger body of detailed beliefs, and of providing an intelligible picture of the world we experience.. Alt
作者: 征兵    時(shí)間: 2025-3-26 16:24
rd the development of more and more comprehensive unification of the various fields of science. Newton fused terrestrial and planetary motions into a unified theory at the end of the seventeenth century. But it was in the second half of the nineteenth century that unification of scientific fields be
作者: calumniate    時(shí)間: 2025-3-26 16:57
https://doi.org/10.1007/978-3-642-75370-1Alzheimer‘s disease; Alzheimer′s disease; clinical trial; depression; development; diagnosis; drug; memory;
作者: A精確的    時(shí)間: 2025-3-26 21:52

作者: –DOX    時(shí)間: 2025-3-27 03:57
Methodology of the Evaluation of Psychotropic Drugs978-3-642-75370-1Series ISSN 0931-6795
作者: NOT    時(shí)間: 2025-3-27 09:01
Psychopharmacology Serieshttp://image.papertrans.cn/m/image/632183.jpg
作者: Cryptic    時(shí)間: 2025-3-27 13:01

作者: 針葉    時(shí)間: 2025-3-27 17:28
Measuring the Efficacy of Psychotropic Drugs: Clinical Symptoms and Rating Scalesheir effect on the pathophysiology of mental disorders. The efficacy of psychotropic drugs in the treatment of acute episodes can only be evidenced by the reduction of indicators of the severity of the target symptomatology in the controlled drug trials.
作者: 敵意    時(shí)間: 2025-3-27 21:37
Ascertainment of Side Effects in Psychopharmacologic Clinical Trialshe efficacy of proposed therapeutic agents. This has come about for a variety of reasons including the amendment to the U.S. Food, Drug, and Cosmetics Law in 1962 that requires proof of efficacy before marketing of prescription medications is permitted. Assessment or proof of safety prior to marketing had been a requirement for many years.
作者: infringe    時(shí)間: 2025-3-28 00:15

作者: 使迷醉    時(shí)間: 2025-3-28 04:51

作者: Desert    時(shí)間: 2025-3-28 09:00
0931-6795 in the establishment of a convincing methodology for demonstrating the efficacy of treatments. The first tricyclic and neuroleptic drugs were tested for their efficacy in psychiatric disorders along the lines of these methodological developments, but subsequent trials with psychotropic drugs did no
作者: 角斗士    時(shí)間: 2025-3-28 13:30

作者: PATHY    時(shí)間: 2025-3-28 15:46

作者: corn732    時(shí)間: 2025-3-28 22:00

作者: AVID    時(shí)間: 2025-3-28 23:42
National and International Guidelines for the Conduct of Clinical Trials of Psychotropic Drugs that even colleagues, who have been working on similar documents for years, seem much inclined to forget about so much existing printed material and restart the discussion from the zero point every time..
作者: chalice    時(shí)間: 2025-3-29 06:59
Statistical Issues: Sample Size and Dropouton in the design, and place great weight on the results of the contrast between placebo and standard. Thus, the first jump in the evolution of clinical trials design has usually been the “three cell” design (two actives and a placebo cell).
作者: Paraplegia    時(shí)間: 2025-3-29 09:53
Diagnoses as Selection Criteria in Drug Trialsed the popularity of typological models (Strauss 1973, 1975, 1986) which reflect more the medical thinking in the form of categories (like health versus illness). Clinical practice in psychiatry also favors the use of diagnostic categories for indication and selection of patients for treatment.
作者: interior    時(shí)間: 2025-3-29 12:07
Functional Classification and Response to Psychotropic Drugs syndrome” and then, due to the growing acceptance of DSM-III, to the major depressive episode. Now, even further indications for antidepressants, especially for panic disorder and generalized anxiety disorder, have been suggested.
作者: 蕁麻    時(shí)間: 2025-3-29 16:11

作者: Affection    時(shí)間: 2025-3-29 20:12

作者: 除草劑    時(shí)間: 2025-3-30 01:15
for this, as well as for many other things, I will always be grateful. My father-in-law, the late Joseph Millstone, a man I dearly loved and respected, also provided me with support during the time I was working on this book. His death is for me an incalculable loss, and his memory is something I w
作者: 泥土謙卑    時(shí)間: 2025-3-30 07:55

作者: 言行自由    時(shí)間: 2025-3-30 11:54

作者: neurologist    時(shí)間: 2025-3-30 16:04
T. H. Crook,B. A. Johnson,G. J. Larrabeest-empiricist debate. I restrict my attention to BonJour’s indispensability arguments. He argues that unless one is a radical skeptic about justification, there must be some substantive a priori justification. . BonJour refers to this argument as “the master argument” of his book.. He argues that un
作者: GRACE    時(shí)間: 2025-3-30 19:16
F. Hohagen,M. Bergerst-empiricist debate. I restrict my attention to BonJour’s indispensability arguments. He argues that unless one is a radical skeptic about justification, there must be some substantive a priori justification. . BonJour refers to this argument as “the master argument” of his book.. He argues that un




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