標(biāo)題: Titlebook: Meningococcal Vaccines; Methods and Protocol Andrew J. Pollard,Martin C.J. Maiden Book 2001 Springer Science+Business Media New York 2001 i [打印本頁] 作者: emanate 時間: 2025-3-21 18:01
書目名稱Meningococcal Vaccines影響因子(影響力)
作者: 報復(fù) 時間: 2025-3-21 20:50 作者: Aura231 時間: 2025-3-22 04:27
978-1-4899-4225-8Springer Science+Business Media New York 2001作者: JOT 時間: 2025-3-22 04:51 作者: Anthrp 時間: 2025-3-22 11:59 作者: BIPED 時間: 2025-3-22 13:15
Methods in Molecular Medicinehttp://image.papertrans.cn/m/image/630609.jpg作者: Discrete 時間: 2025-3-22 17:55 作者: Semblance 時間: 2025-3-23 01:13 作者: 不透明性 時間: 2025-3-23 02:19
Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity,Proteins with intrinsic mitogenic properties are widely represented in prokaryotes, such as in different . species (.–.), . (.), and . (.). Specifically, several bacterial porins of ., and pathogenic . species have been shown to induce nonspecific proliferation of lymphocytes (.–.).作者: urethritis 時間: 2025-3-23 07:17
Early Experiences with Nasal Vaccines against Meningococcal Disease,In common with most infectious agents, meningococci invade mucosal membranes before causing disease (.). An attractive vaccine strategy is therefore to induce immunological responses at the mucosal surfaces, with the possibility of blocking microbial invasion, as well as to induce systemic immunity with the capacity of inactivating the microbes.作者: Protein 時間: 2025-3-23 13:36
Book 2001the menace of the meningococcus has been high on the list of public health prio- ties. Few if any pathogens surpass the meningococcus in the rapidity and sev- ity with which it devastates previously healthy individuals. The challenge of understanding the biology of this fascinating microbe is immens作者: 斷斷續(xù)續(xù) 時間: 2025-3-23 13:52
Recombinant Proteins in Vaccine Development,lved in the preparation of recombinant class 1 OMP for vaccine development. This integrated set of methods can also be readily used to study the potential of other meningococcal OMP as vaccine candidates, and moreover, their utilities make them attractive for vaccine studies relating to many other human pathogens.作者: delegate 時間: 2025-3-23 20:15 作者: nascent 時間: 2025-3-24 02:00
1543-1894 the beginning of the twentieth centuries, the menace of the meningococcus has been high on the list of public health prio- ties. Few if any pathogens surpass the meningococcus in the rapidity and sev- ity with which it devastates previously healthy individuals. The challenge of understanding the bi作者: crease 時間: 2025-3-24 05:42
Protein-Polysaccharide Conjugation,ection of the population most vulnerable to bacterial meningitis, and second, some polysaccharides are only weakly immunogenic in adults. To overcome these deficiencies, a new generation of semisynthetic vaccines have been developed based on the conjugation of polysaccharide to protein carriers.作者: cluster 時間: 2025-3-24 08:44 作者: 無禮回復(fù) 時間: 2025-3-24 10:43 作者: kindred 時間: 2025-3-24 15:25
,-Propionylation,f α(2–8)-linked sialic-acid residues (.) and similar structures have also been identified in the humantissue antigens, from short trimeric fragments found in mammalian gangliosides (.) to long decameric fragments observed in the glycoproteins of neural-cell adhesion molecules (N-CAMs) (.).作者: Emasculate 時間: 2025-3-24 22:39
Identification of Peptides that Mimic , LOS Epitopes Via the Use of Combinatorial Phage-Display Libigopeptides to stimulate antibody responses that are cross-reactive with LOS antigens expressed by serogroup B . strains. An integral part of these studies has been the application of combinatorial phage-display technology. Described here is an overview of the methods that we have utilized to identify peptide mimics of LOS epitopes.作者: intrigue 時間: 2025-3-25 03:12 作者: obscurity 時間: 2025-3-25 05:18
Carl E. Frasch,Loek van Alphen,Johan Holst,Jan T. Poolman,Einar Rosenqvist, Ingenieure und Betriebswirte zusammen?..Wie lassen sich Entwicklungsarbeiten beschleunigen?..Wie werden Innovationsideen bewertet? ..Wie lange ben?tigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche M?glichkeiten existieren作者: Cardioversion 時間: 2025-3-25 08:26 作者: Heterodoxy 時間: 2025-3-25 14:39 作者: Anterior 時間: 2025-3-25 17:59 作者: 某人 時間: 2025-3-25 20:23
Alexei A. Delvig,John H. Robinson,Lee Wetzler, Ingenieure und Betriebswirte zusammen?..Wie lassen sich Entwicklungsarbeiten beschleunigen?..Wie werden Innovationsideen bewertet? ..Wie lange ben?tigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche M?glichkeiten existieren作者: exhilaration 時間: 2025-3-26 01:36 作者: 離開 時間: 2025-3-26 06:46
Elisabeth Wedege, Ingenieure und Betriebswirte zusammen?..Wie lassen sich Entwicklungsarbeiten beschleunigen?..Wie werden Innovationsideen bewertet? ..Wie lange ben?tigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche M?glichkeiten existieren作者: ANN 時間: 2025-3-26 11:32
ge activity in the use of modified basket were found to be 10 kgs and 0.97. Use of modified basket for paddy storage activity increases output, enhance efficiency, comfort, and workable life and reduces drudgery and health hazards of farm women.作者: Fibroid 時間: 2025-3-26 14:31
Richard F. Collins,Jeremy P. Derricken?..Wie werden Innovationsideen bewertet? ..Wie lange ben?tigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche M?glichkeiten existieren978-3-540-68115-1Series ISSN 2512-5281 Series E-ISSN 2512-529X 作者: 哪有黃油 時間: 2025-3-26 17:40
Janet Suker,Bambos M. Charalambousen?..Wie werden Innovationsideen bewertet? ..Wie lange ben?tigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche M?glichkeiten existieren978-3-540-68115-1Series ISSN 2512-5281 Series E-ISSN 2512-529X 作者: 小畫像 時間: 2025-3-27 00:36 作者: regale 時間: 2025-3-27 04:57
Paul J. Brett,Ian M. Feavers,Bambos M. Charalambousen?..Wie werden Innovationsideen bewertet? ..Wie lange ben?tigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche M?glichkeiten existieren978-3-540-68115-1Series ISSN 2512-5281 Series E-ISSN 2512-529X 作者: DAFT 時間: 2025-3-27 07:42
Johan Holst,Bj?rn Hanebergen?..Wie werden Innovationsideen bewertet? ..Wie lange ben?tigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche M?glichkeiten existieren978-3-540-68115-1Series ISSN 2512-5281 Series E-ISSN 2512-529X 作者: 出來 時間: 2025-3-27 10:50
Andrew R. Gorringe,Karen M. Reddin,Pierre Voet,Jan T. Poolmanen?..Wie werden Innovationsideen bewertet? ..Wie lange ben?tigt heute eine Idee bis zum fertigen Marktprodukt?..Wie beziehen kluge Unternehmen den Kunden in die Entwicklung ein?..Welche M?glichkeiten existieren978-3-540-68115-1Series ISSN 2512-5281 Series E-ISSN 2512-529X 作者: 移植 時間: 2025-3-27 16:29
Carmen Arigita,Wim Jiskoot,Matthijs R. Graaf,Gideon F. A. Kersten作者: Acclaim 時間: 2025-3-27 21:44
Meningococcal Vaccines and Vaccine Developments,ve protection. This overview traces the development of the existing licensed vaccines and examines the prospects of vaccine candidates that are currently under development or subject to clinical evaluation.作者: 惰性氣體 時間: 2025-3-27 23:56
Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens D peptide or oligosaccharide that binds to the antibody in question and then determination of the structure of the bound antigen by X-ray crystallography. Clearly, this has the limitation that only well-defined continuous epitopes can be studied in this way, but fortunately this is frequently the cas作者: 圓柱 時間: 2025-3-28 06:06
Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetimultitude of different applications of biosensor technology including measurement of concentration, kinetic analysis, structural studies, fermentation monitoring, receptor-cell interactions, and equilibrium analysis. The most widespread applications have been to protein-protein interactions, in part作者: EXULT 時間: 2025-3-28 07:12
Construction of porA Mutants,h experimental outer membrane-derived vaccines have shown that PorA is a major inducer of bactericidal antibodies (.–.), making it a crucial component of any meningococcal vaccine. These antibodies are highly subtype-specific. Epidemic strains tend to be clonal and mainly express a single PorA subty作者: fiscal 時間: 2025-3-28 12:44
Construction of LPS Mutants,n several ways. First, the cell surface-exposed oligosaccharide part may contain epitopes recognized by bactericidal or otherwise protective antibodies; however, the presence of host-identical structures such as the terminal lacto-.-neotetraose means that the possibility of inducing autoimmune patho作者: 蝕刻術(shù) 時間: 2025-3-28 17:35
1543-1894 molecular tools with which to lay bare the secrets of the meningococcus. The results of this ambitious and welcome v- ume represent an exciting and much needed resource for all of us in the field.978-1-4899-4225-8978-1-59259-148-0Series ISSN 1543-1894 Series E-ISSN 1940-6037 作者: 用肘 時間: 2025-3-28 18:58
Book 2001am of experts gathered by Andy Pollard and Martin Maiden converge to p- vide an impressive accumulation of molecular tools with which to lay bare the secrets of the meningococcus. The results of this ambitious and welcome v- ume represent an exciting and much needed resource for all of us in the field.作者: rectum 時間: 2025-3-29 00:15 作者: 禁令 時間: 2025-3-29 05:44
Immune Response and Host-Pathogen Interactions,ife is an almost universal experience but clinically overt disease is unusual except during epidemics. This overview considers the relationship between the meningococcus and humans, reviewing current immunological and molecular understanding of this interaction of relevance to development of immunog作者: Monocle 時間: 2025-3-29 08:09 作者: altruism 時間: 2025-3-29 15:16 作者: intangibility 時間: 2025-3-29 17:40 作者: 敵意 時間: 2025-3-29 23:17 作者: 委托 時間: 2025-3-30 03:46
Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens D more rational approach to vaccine design. X-ray crystallography has been outstandingly successful in delineating the detailed chemical interactions that are responsible for the high affinity and high selectivity of antibody-antigen interactions (.). Although a number of X-ray structures of OMPs hav作者: peptic-ulcer 時間: 2025-3-30 06:42 作者: Petechiae 時間: 2025-3-30 09:35
Construction of porA Mutants,ther one being the PorB or class 2/3 protein. It folds into a 16-stranded β-barrel structure, which is now well-established for bacterial porins, in which seven loops are exposed at the cell surface and the remaining one forms the constriction of the pore (.,.). There are approx 20 different serosub作者: 公司 時間: 2025-3-30 14:23
Construction of LPS Mutants, at both ends with diphosphoethanolamine, to which an oligosaccharide chain of up to 10 sugar residues is attached (.,.). It lacks a long repeating O-antigen side chain, as is typically found in many ., and is therefore also sometimes referred to as lipooligosaccharide or LOS. The oligosaccharide pa作者: 幾何學(xué)家 時間: 2025-3-30 16:34
Recombinant Proteins in Vaccine Development,ntial of these proteins would be facilitated by the production of pure recombinant protein, free from other components of the . outer membrane. At present, the class 1 outer-membrane protein (OMP) is generally regarded as the most promising candidate. In this chapter, we describe four protocols invo作者: calorie 時間: 2025-3-30 21:59 作者: 高射炮 時間: 2025-3-31 01:17
Animal Models for Meningococcal Disease, bacteria with whole tissues and the humoral and cellular immune systems can be assessed. Animal-infection models are also of great importance for the assessment of the protective efficacy of existing and candidate vaccines. However, the relevance of these animal models to human disease and how well作者: 容易做 時間: 2025-3-31 07:57 作者: COUCH 時間: 2025-3-31 11:38 作者: 歹徒 時間: 2025-3-31 16:03 作者: Offbeat 時間: 2025-3-31 18:24 作者: ARK 時間: 2025-4-1 00:14
Leanne M. DeWinter,Anthony B. Schryversdem Ma?e mit dem Produktdesign besch?ftigen. Produkte, die in der Leistung, der Handhabung und in der Gestaltung exakt den Vorstellungen der Kunden entsprechen, bringen in der Vermarktung die notwendigen Wettbewerbsvorteile. Jedes Unternehmen m?chte mit derartigen Innovationen neue M?rkte erobern un作者: 雜役 時間: 2025-4-1 03:16
Richard F. Collins,Jeremy P. Derrickn chemischen Unternehmens.Kundenorientierte Produktentwicklu.Vorst?nde, Ressort- und Bereichsleiter, Produkt- und Verfahrensentwickler und Marketingdirektoren müssen sich in der chemischen Industrie in zunehmendem Ma?e mit dem Produktdesign besch?ftigen. Produkte, die in der Leistung, der Handhabung作者: Homocystinuria 時間: 2025-4-1 07:19 作者: 彎曲道理 時間: 2025-4-1 12:34 作者: 討厭 時間: 2025-4-1 17:47
Peter van der Ley,Liana Steeghsn chemischen Unternehmens.Kundenorientierte Produktentwicklu.Vorst?nde, Ressort- und Bereichsleiter, Produkt- und Verfahrensentwickler und Marketingdirektoren müssen sich in der chemischen Industrie in zunehmendem Ma?e mit dem Produktdesign besch?ftigen. Produkte, die in der Leistung, der Handhabung
