標(biāo)題: Titlebook: Membrane Transporters in Drug Discovery and Development; Methods and Protocol Qing Yan Book 2010 Humana Press 2010 In silico.PCR.bioinforma [打印本頁] 作者: otitis-externa 時(shí)間: 2025-3-21 17:56
書目名稱Membrane Transporters in Drug Discovery and Development影響因子(影響力)
書目名稱Membrane Transporters in Drug Discovery and Development影響因子(影響力)學(xué)科排名
書目名稱Membrane Transporters in Drug Discovery and Development網(wǎng)絡(luò)公開度
書目名稱Membrane Transporters in Drug Discovery and Development網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Membrane Transporters in Drug Discovery and Development被引頻次
書目名稱Membrane Transporters in Drug Discovery and Development被引頻次學(xué)科排名
書目名稱Membrane Transporters in Drug Discovery and Development年度引用
書目名稱Membrane Transporters in Drug Discovery and Development年度引用學(xué)科排名
書目名稱Membrane Transporters in Drug Discovery and Development讀者反饋
書目名稱Membrane Transporters in Drug Discovery and Development讀者反饋學(xué)科排名
作者: Osteoarthritis 時(shí)間: 2025-3-21 22:24 作者: antipsychotic 時(shí)間: 2025-3-22 01:48 作者: 合法 時(shí)間: 2025-3-22 07:03 作者: ODIUM 時(shí)間: 2025-3-22 12:14 作者: VICT 時(shí)間: 2025-3-22 14:28
cing the principles of programming languages, using the Java language as a support, Gilles Dowek provides the necessary fundamentals of this language as a first objective..It is important to realise that knowledge of a single programming language is not really enough. To be a good programmer, you sh作者: 吃掉 時(shí)間: 2025-3-22 20:03
Qing Yany protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This te- book is intended to serve as a useful tool to spread information on strategies for lung protection during heart surgery with CPB. Emphasis on pulmonary protection will be turned to lung perfusion as作者: 可耕種 時(shí)間: 2025-3-22 23:18
Qing Yan M.D., Ph.D.y protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This te- book is intended to serve as a useful tool to spread information on strategies for lung protection during heart surgery with CPB. Emphasis on pulmonary protection will be turned to lung perfusion as作者: Euphonious 時(shí)間: 2025-3-23 02:32 作者: 錢財(cái) 時(shí)間: 2025-3-23 07:54 作者: 秘方藥 時(shí)間: 2025-3-23 12:47
Takeo Nakanishi,Douglas D. Ross,Keisuke Mitsuoka.Includes supplementary material: Over the past ?fty years, advanced techniques and strategies have arisen in the ?eld of myocardial protection. Meticulous trials, focusing on pulmonary protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This te- book is intend作者: 敘述 時(shí)間: 2025-3-23 14:27
Anna Maria Calcagno,Suresh V. Ambudkar.Includes supplementary material: Over the past ?fty years, advanced techniques and strategies have arisen in the ?eld of myocardial protection. Meticulous trials, focusing on pulmonary protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This te- book is intend作者: judicial 時(shí)間: 2025-3-23 18:14 作者: 取回 時(shí)間: 2025-3-23 22:13 作者: 過份 時(shí)間: 2025-3-24 05:17 作者: 反省 時(shí)間: 2025-3-24 08:00 作者: preeclampsia 時(shí)間: 2025-3-24 14:24
Corey Westerfeldy protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This te- book is intended to serve as a useful tool to spread information on strategies for lung protection during heart surgery with CPB. Emphasis on pulmonary protection will be turned to lung perfusion as作者: lattice 時(shí)間: 2025-3-24 14:55
Hans P.M. M. Lauritzeny protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This te- book is intended to serve as a useful tool to spread information on strategies for lung protection during heart surgery with CPB. Emphasis on pulmonary protection will be turned to lung perfusion as作者: meretricious 時(shí)間: 2025-3-24 19:04 作者: Enervate 時(shí)間: 2025-3-25 01:50 作者: Dna262 時(shí)間: 2025-3-25 06:01 作者: 迎合 時(shí)間: 2025-3-25 07:42
Stefan Br?ery protection during heart surgery requiring cardiopulmonary bypass (CPB), have been missing. This te- book is intended to serve as a useful tool to spread information on strategies for lung protection during heart surgery with CPB. Emphasis on pulmonary protection will be turned to lung perfusion as作者: onlooker 時(shí)間: 2025-3-25 15:06 作者: Decimate 時(shí)間: 2025-3-25 19:07 作者: CLOUT 時(shí)間: 2025-3-25 20:24
Chris J. Roome,Ruth M. Empsonsciences would, in the future, be stated as rigorously as the “hard sciences” that study such nonliving phenomena as temperature, distance, and the interaction of chemical elements. Principles of Quantitative Living Systems Science, the first of a planned series of three books, begins an attempt to 作者: PAC 時(shí)間: 2025-3-26 02:12
Membrane Transporters and Drug Development: Relevance to Pharmacogenomics, Nutrigenomics, Epigeneti are essential for fundamental cellular functions and normal physiological processes. These molecules influence drug absorption and distribution and play key roles in drug therapeutic effects. A primary goal of current research in drug discovery and development is to fully understand the interaction作者: 合乎習(xí)俗 時(shí)間: 2025-3-26 07:55
Bioinformatics for Transporter Pharmacogenomics and Systems Biology: Data Integration and Modeling l knowledge. Bioinformatics is facing challenges in helping with finding the relationships between genetic structures and functions, analyzing genotype–phenotype associations, and understanding gene–environment interactions at the systems level. One of the most important issues in bioinformatics is 作者: 委派 時(shí)間: 2025-3-26 11:40 作者: 清唱?jiǎng)?nbsp; 時(shí)間: 2025-3-26 14:25
,Targeting Drug Transporters – Combining In Silico and In Vitro Approaches to Predict In Vivo,absorption, distribution, metabolism, excretion, and toxicity (ADME/Tox) properties of therapeutic molecules. Over the past decade, numerous drug transporters have been cloned and considerable progress has been made toward understanding the molecular characteristics of individual transporters. In th作者: 爵士樂 時(shí)間: 2025-3-26 17:59 作者: 我說不重要 時(shí)間: 2025-3-27 00:09
Analysis of Expression of Drug Resistance-Linked ABC Transporters in Cancer Cells by Quantitative R accurate and reproducible detection of transcript levels. As a consequence, qRT-PCR has become a popular technique for assessing gene expression levels and is now the gold standard. In this chapter, qRT-PCR using two distinct chemistries, SYBR Green and TaqMan, are described. We compare ABC transpo作者: 委托 時(shí)間: 2025-3-27 04:01
Fluorescence Studies of Drug Binding and Translocation by Membrane Transporters,d uptake in the intestine and cannot gain access to the brain. Three multidrug efflux pumps of the ABC superfamily (P-glycoprotein/ABCB1, MRP1/ABCC1, and BCRP/ABGG2) are responsible for most drug transport out of mammalian cells. P-glycoprotein is the best characterized of the ABC drug transporters.作者: Lipohypertrophy 時(shí)間: 2025-3-27 08:56 作者: Instantaneous 時(shí)間: 2025-3-27 12:33 作者: 虛假 時(shí)間: 2025-3-27 17:35 作者: Minutes 時(shí)間: 2025-3-27 21:09
ABC Transporters in Ophthalmic Disease,maculatus, cone–rod dystrophy, retinitis pigmentosa, and age-related macular degeneration. The genetic and molecular pathways involved in the pathogenesis of ABCR-related ophthalmic conditions will be explored. Future diagnostic and therapeutic objectives for these diseases will also be discussed.作者: opportune 時(shí)間: 2025-3-27 22:05
Imaging of Protein Translocation In Situ in Skeletal Muscle of Living Mice,k of insulin-resistant states and type II diabetes. Therefore it is highly pathophysiologically relevant to perform detailed studies of insulin signaling inside skeletal muscle cells in order to elucidate the specific molecular events during both normal and insulin-resistant conditions. So far, cell作者: 過時(shí) 時(shí)間: 2025-3-28 05:40
Glucose Transporters in Parasitic Protozoa,agents of leishmaniasis, African sleeping sickness, and malaria. Glucose transporters and the genes that encode them have been identified in each of these parasites and their functional properties have been scrutinized. These transporters are related in sequence and structure to mammalian facilitati作者: 珊瑚 時(shí)間: 2025-3-28 07:06 作者: 經(jīng)典 時(shí)間: 2025-3-28 13:06 作者: Oafishness 時(shí)間: 2025-3-28 16:56 作者: 箴言 時(shí)間: 2025-3-28 21:05
Measurement of Intracellular pH,pH is of interest in studying many processes, including pH regulatory transport proteins. Key approaches that have been used to determine intracellular pH include pH-sensitive microelectrodes, nuclear magnetic resonance, and pH-sensitive fluorescent proteins. Here we review these approaches while pr作者: Gullible 時(shí)間: 2025-3-29 00:43
,Measurement of Plasma Membrane Calcium–Calmodulin-Dependent ATPase (PMCA) Activity,racellular compartment. Although in excitable cells such as skeletal and cardiac muscle cells PMCA has been shown to play only a minor role in regulating global intracellular calcium concentration, increasing evidence points to an important role for PMCA in signal transduction, in particular in the 作者: MIME 時(shí)間: 2025-3-29 04:25 作者: 沙發(fā) 時(shí)間: 2025-3-29 08:06
Methods to Evaluate Transporter Activity in Cancer, of delivering a drug to the target tissues, avoiding distribution to other tissues, and improving oral bioavailability. This chapter focuses on methodology to analyze the activity of transporters that are involved in drug transport.作者: 狂熱文化 時(shí)間: 2025-3-29 11:32 作者: Palpate 時(shí)間: 2025-3-29 17:58 作者: Adulate 時(shí)間: 2025-3-29 20:20
Site-Directed Mutagenesis in the Study of Membrane Transporters,res for many membrane transporters other molecular tools need to be employed. In vitro site-directed mutagenesis is one method that has the capacity to provide both structural information and identification of the role of individual residues and/or regions of a protein that are involved in function.作者: agenda 時(shí)間: 2025-3-30 03:46
, Oocytes,the analysis of membrane transporters in this system, including preparation of oocytes, assays of transport activity, protocols for immunostaining and fluorescence microscopy, and other assays to study surface expression.作者: 窒息 時(shí)間: 2025-3-30 05:58
Measurement of Intracellular pH,r pH include pH-sensitive microelectrodes, nuclear magnetic resonance, and pH-sensitive fluorescent proteins. Here we review these approaches while providing details on the use of pH-sensitive fluorescent dyes to measure cytosolic pH.作者: CALL 時(shí)間: 2025-3-30 10:39 作者: 大方一點(diǎn) 時(shí)間: 2025-3-30 15:47 作者: Mediocre 時(shí)間: 2025-3-30 20:15
,Measurement of Plasma Membrane Calcium–Calmodulin-Dependent ATPase (PMCA) Activity,tone. Here we describe a method in determining PMCA activity in the microsomal membrane preparation from cultured cells that overexpress specific isoform of PMCA by using modified coupled enzyme assay.作者: –scent 時(shí)間: 2025-3-30 22:53 作者: 發(fā)芽 時(shí)間: 2025-3-31 02:08 作者: 收藏品 時(shí)間: 2025-3-31 06:41 作者: BOLT 時(shí)間: 2025-3-31 11:27 作者: MAPLE 時(shí)間: 2025-3-31 15:16
Takeo Nakanishi,Douglas D. Ross,Keisuke Mitsuokardiothoracic fellows, radiologists, basic sciences physicians, cardiologists, pulmonary medicine physicians, perfusi- ists, nurses, students, and researchers. This textbook has 7 secti978-1-4471-5706-9978-1-84996-308-4作者: SCORE 時(shí)間: 2025-3-31 18:57
Anna Maria Calcagno,Suresh V. Ambudkarrdiothoracic fellows, radiologists, basic sciences physicians, cardiologists, pulmonary medicine physicians, perfusi- ists, nurses, students, and researchers. This textbook has 7 secti978-1-4471-5706-9978-1-84996-308-4作者: 放逐 時(shí)間: 2025-4-1 00:39 作者: 品嘗你的人 時(shí)間: 2025-4-1 03:16 作者: famine 時(shí)間: 2025-4-1 07:32
