標(biāo)題: Titlebook: Mechanisms of Genome Protection and Repair; Dmitry O. Zharkov Book 2020 The Editor(s) (if applicable) and The Author(s), under exclusive l [打印本頁(yè)] 作者: 決絕 時(shí)間: 2025-3-21 19:55
書目名稱Mechanisms of Genome Protection and Repair影響因子(影響力)
書目名稱Mechanisms of Genome Protection and Repair影響因子(影響力)學(xué)科排名
書目名稱Mechanisms of Genome Protection and Repair網(wǎng)絡(luò)公開度
書目名稱Mechanisms of Genome Protection and Repair網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Mechanisms of Genome Protection and Repair被引頻次
書目名稱Mechanisms of Genome Protection and Repair被引頻次學(xué)科排名
書目名稱Mechanisms of Genome Protection and Repair年度引用
書目名稱Mechanisms of Genome Protection and Repair年度引用學(xué)科排名
書目名稱Mechanisms of Genome Protection and Repair讀者反饋
書目名稱Mechanisms of Genome Protection and Repair讀者反饋學(xué)科排名
作者: Loathe 時(shí)間: 2025-3-21 21:31
Protein Engineering of DNA-Dependent Enzymes,ne of the main goals of modern protein engineering. The field of protein engineering is growing intensively, and different strategies were developed for the creation of enzymes with new properties. While there is plenty of methods and instruments, all modern protein engineering strategies could be d作者: Kinetic 時(shí)間: 2025-3-22 02:27 作者: Introduction 時(shí)間: 2025-3-22 05:51
Impact of PARP1, PARP2 & PARP3 on the Base Excision Repair of Nucleosomal DNA,m is responsible for the repair of the most frequent DNA lesions. On the other hand, the formation of poly(ADP-ribose) is one of the main DNA damage response reactions that is catalysed by members of the PARP family. PARP1, which belongs to the PARP family and performs approximately 90% of PAR synth作者: MEET 時(shí)間: 2025-3-22 09:08
Base Excision Repair in Chromatin and the Requirement for Chromatin Remodelling, is essential for the maintenance of genome integrity and thus in the prevention of the development of human diseases, including premature ageing, neurodegenerative diseases and cancer. Within the cell, DNA is usually packaged with histone proteins to form chromatin which imposes major constraints o作者: 連詞 時(shí)間: 2025-3-22 14:24 作者: thalamus 時(shí)間: 2025-3-22 20:58
Mystery of Expansion: DNA Metabolism and Unstable Repeats,larly the propensity to change the repeat unit number, is responsible for 36 well-known neurodegenerative human disorders. The mechanism of repeat expansion has been an unsolved question for more than 20?years. There are a few hypotheses describing models of mutation development. Every hypothesis is作者: AXIOM 時(shí)間: 2025-3-22 22:02 作者: –FER 時(shí)間: 2025-3-23 03:52
Biotransformation and Toxicities of Aristolochic Acids,been extended by the addition of aristolochic acids (AAs). AAs occur primarily in . herbs, which are used extensively in folk medicines, including Traditional Chinese Medicine. Ingestion of AAs results in chronic renal disease and cancer. Despite importation bans imposed by certain countries, herbal作者: Mosaic 時(shí)間: 2025-3-23 06:31 作者: 他姓手中拿著 時(shí)間: 2025-3-23 11:23
Studying ALS: Current Approaches, Effect on Potential Treatment Strategy,only two disease modifying therapeutic options are available for the patients with ALS, although they show very modest effect on disease course. The main reason of failure in the field of pharmacological correction of ALS is inability to untangle complex relationships taking place during ALS initiat作者: Perennial長(zhǎng)期的 時(shí)間: 2025-3-23 15:27 作者: 符合你規(guī)定 時(shí)間: 2025-3-23 18:02
Viktoriya S. Sidorenkos a result, there is a world-wide effort in upgrading current networks with high-capacity fiber-optic links that can potentially deliver Tera-bits/sec bandwidth. The . (WDM) is an effective technique for utilizing the large bandwidth of an optical fiber. By allowing multiple simultaneous transmissio作者: 安撫 時(shí)間: 2025-3-24 01:37
Bing Yu,Mengdi Chen,Inga Grin,Chunquan Ma basic considerations should be kept in mind when doing ESD protection circuit design, i.e., to ensure uniform current distribution and to make area efficient layout. Practical ESD-enhancement layout techniques include to use smoothed geometries, to set up adequate critical spacing, to properly plac作者: accessory 時(shí)間: 2025-3-24 05:52 作者: 受傷 時(shí)間: 2025-3-24 10:19 作者: 猛然一拉 時(shí)間: 2025-3-24 13:23
Kinetic Milestones of Damage Recognition by DNA Glycosylases of the Helix-Hairpin-Helix Structural stages that make the largest contribution to the specificity of the enzyme for DNA substrates. These data provide an opportunity to gain further insight into the structural and dynamic principles underlying the enzymatic processes that ensure highly efficient functioning of the repair-protective sys作者: Anal-Canal 時(shí)間: 2025-3-24 18:17 作者: Adherent 時(shí)間: 2025-3-24 21:50
Impact of PARP1, PARP2 & PARP3 on the Base Excision Repair of Nucleosomal DNA,syl)ation (PARylation) is thought to regulate the initiation of the BER process at the chromatin level. In this review, we focus on the mechanisms involved in BER in the nucleosomal context and the potential effect of PARylation, which is catalysed by DNA-dependent PARP1, PARP2 and PARP3 proteins, o作者: 不來(lái) 時(shí)間: 2025-3-25 00:24
Base Excision Repair in Chromatin and the Requirement for Chromatin Remodelling,ve. In this review, we summarise the multitude of . studies utilising mononucleosome substrates containing site-specific DNA base damage that demonstrate the requirement for chromatin remodelling to facilitate BER, particularly in occluded regions. We also highlight preliminary evidence to date for 作者: 協(xié)迫 時(shí)間: 2025-3-25 06:36 作者: 靦腆 時(shí)間: 2025-3-25 08:51
,The Detection of 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine in Circulating Cell-Free DNA: A Step Towards Lstress. Patient-specific baselines for oxidative damage may be established by measuring of 8-oxo-dG in circulating DNA. Longitudinal profiling of oxiDNA may aid in reliable quantification of the effects of various self-administered nutraceutical and lifestyle based health interventions. Development 作者: 含糊 時(shí)間: 2025-3-25 15:15
Biotransformation and Toxicities of Aristolochic Acids,to how cellular enzymes promote activation of AAs and how the reactive species selectively bind to DNA and kidney proteins. In this review, I describe pathways for AAs biotransformation, adduction, and mutagenesis, emphasizing novel methods and ideas contributing to our present understanding of AA t作者: Foment 時(shí)間: 2025-3-25 17:30 作者: paroxysm 時(shí)間: 2025-3-25 20:16 作者: 蹣跚 時(shí)間: 2025-3-26 01:02 作者: Reservation 時(shí)間: 2025-3-26 05:39
Viktoriya S. Sidorenko as a broadcast-and-select network in which all the input nodes are combined using a passive star coupler, and the mixed optical information is broadcast to all destinations. To unleash the potential of single-hop WDM passive star networks, effective medium access control (MAC) protocols are needed 作者: finale 時(shí)間: 2025-3-26 12:18 作者: fledged 時(shí)間: 2025-3-26 14:06 作者: 好開玩笑 時(shí)間: 2025-3-26 17:25 作者: 自由職業(yè)者 時(shí)間: 2025-3-27 00:03
0065-2598 ory functions of bulky covalent modifications such as poly(ADP)ribosylation and ubiquitylation in DNA damage response, especially in the context of chromatin remodelling. As opposed to DNA repair, damage tolera978-3-030-41285-2978-3-030-41283-8Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 諷刺 時(shí)間: 2025-3-27 03:12 作者: 車床 時(shí)間: 2025-3-27 08:32 作者: palliative-care 時(shí)間: 2025-3-27 09:54
A Multifunctional Protein PolDIP2 in DNA Translesion Synthesis,ver PolDIP2 functions in DNA translesion synthesis and repair are not fully understood. In this review, we address the functional interaction of PolDIP2 with human DNA polymerases and discuss the possible functions in DNA damage response.作者: 媽媽不開心 時(shí)間: 2025-3-27 14:39 作者: Formidable 時(shí)間: 2025-3-27 20:01 作者: 是貪求 時(shí)間: 2025-3-27 23:34
0065-2598 gle proteins at an atomistic resolution to whole organisms.FDNA is under constant challenge from environmental and endogenous metabolic assaults. Several layers of defence and repair systems allow cells to maintain stable genomes; in humans, dysfunction of these systems leads to cancer, neurodegener作者: 壕溝 時(shí)間: 2025-3-28 04:25
Book 2020tain stable genomes; in humans, dysfunction of these systems leads to cancer, neurodegeneration, and other pathologies. At the same time, recently it had emerged that targeted and regulated DNA damage and repair is a mechanism underlying several important cellular processes such as epigenetic demeth作者: antipsychotic 時(shí)間: 2025-3-28 09:38
Dmitry O. ZharkovDNA repair, the topic of this book, helps each human cell to survive millions of hits damaging its genome daily.Covers many levels, from single proteins at an atomistic resolution to whole organisms.F作者: nocturnal 時(shí)間: 2025-3-28 11:45
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/m/image/628724.jpg作者: 大方一點(diǎn) 時(shí)間: 2025-3-28 17:48
978-3-030-41285-2The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl作者: Platelet 時(shí)間: 2025-3-28 19:58 作者: ABIDE 時(shí)間: 2025-3-29 02:41
https://doi.org/10.1007/978-3-030-41283-8DNA damage; DNA repair; DNA tolerance; Cell response; Signaling pathway; Oxidative stress作者: 小平面 時(shí)間: 2025-3-29 03:32 作者: excrete 時(shí)間: 2025-3-29 10:37 作者: OASIS 時(shí)間: 2025-3-29 13:18
Introducing Ritualized Europeanization such that a particular stable pattern over the SAM cell population emerges. To this end, we propose an evolutionary algorithm-based approach and investigate different ways to improve the efficiency of the search process. Preliminary results are presented for the Brusselator, a well-known reaction-d作者: outset 時(shí)間: 2025-3-29 19:33
0066-6610 press’. The analysis opens up fascinating insights, afforded by careful reading of primary archival sources, into the reactions of censors confronted with manuscripts by authors seeking permission to publish. T978-94-024-1332-8978-94-017-7346-1Series ISSN 0066-6610 Series E-ISSN 2215-0307 作者: –吃 時(shí)間: 2025-3-29 23:11
