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標(biāo)題: Titlebook: Mechanisms of Gene Regulation: How Science Works; Carsten Carlberg,Ferdinand Molnár Textbook 2020 Springer Nature Switzerland AG 2020 Tran [打印本頁(yè)]

作者: LH941    時(shí)間: 2025-3-21 17:33
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作者: urethritis    時(shí)間: 2025-3-21 21:13

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作者: exophthalmos    時(shí)間: 2025-3-22 16:08
Chromatin Remodeling and Organization, the architecture of the nucleus in differentiated tissues and cell types. In the interchromatin compartment of the nucleus there are sub-nuclear structures, such as transcription factories, that contain high concentrations of Pol II. Transcription factories function as an attractor for commonly reg
作者: 膽汁    時(shí)間: 2025-3-22 21:05
Textbook 2020icantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book
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作者: Dendritic-Cells    時(shí)間: 2025-3-23 08:03
Carsten Carlberg,Ferdinand Molnárhe recent successes is in many ways a saga. The upsurges in the domain were marked by an increasing flow of articles in scientific journals and the publication of several Books (in 1971, 1990 and 1992) which have collected the important accumulated knowledge. Over this period, a considerable number of patents978-1-4419-3296-9978-0-306-46911-4
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作者: 業(yè)余愛(ài)好者    時(shí)間: 2025-3-23 16:22
Carsten Carlberg,Ferdinand Molnárecision, repeatability and the possibility of using only one detecting system due to easy multiplexing with grating arrays..Another example of application presented is the construction of a transmission pass-band filter, applied to suppress the first side lobes in a laser diode spectrum. The used te
作者: Pcos971    時(shí)間: 2025-3-23 21:45
Carsten Carlberg,Ferdinand Molnárelegth modulation mode...The experimental results demonstrated the possibility of selectively detecting 1 ppm levels of chlorocarbons in water with less than 10 minutes total analysis time. A detection limit lower than 50 ppb should be obtained by more sensitive operational modes of the TDLAS system
作者: prolate    時(shí)間: 2025-3-23 22:43
Carsten Carlberg,Ferdinand Molnárt much shorter response times than other LC’s. As to the ways of increasing ruggedness and compactness of LC devices, a viable route appears to be that of exploiting the characteristics of the polymer-dispersed LC’s: these composite materials, besides alleviating the alignment problems, lend themsel
作者: anthropologist    時(shí)間: 2025-3-24 05:55

作者: nitroglycerin    時(shí)間: 2025-3-24 08:59
Carsten Carlberg,Ferdinand Molnárecision, repeatability and the possibility of using only one detecting system due to easy multiplexing with grating arrays..Another example of application presented is the construction of a transmission pass-band filter, applied to suppress the first side lobes in a laser diode spectrum. The used te
作者: Tempor    時(shí)間: 2025-3-24 13:43

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作者: 斗志    時(shí)間: 2025-3-25 01:48
Genes and Chromatin,me is composed of some 20,000 protein-coding genes and an even higher number of genes for non-coding RNAs (ncRNAs) as well as a large number of pseudogenes. An essential condition that a gene can be expressed, ., transcribed into RNA, is that it its regulatory regions, such as transcription start si
作者: 不可磨滅    時(shí)間: 2025-3-25 06:24
Basal Transcriptional Machinery,core of the basal transcriptional machinery that contains a large number of general transcription factors, such as the TATA box binding protein (TBP), many of which are summarized as the TFIID complex. The TATA box is the prototype of a site-specific transcription factor binding site determining the
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作者: disrupt    時(shí)間: 2025-3-25 13:01
A Key Transcription Factor Family: Nuclear Receptors,unctional and structural aspects of transcription factors, such as the interaction with co-activator and co-repressor proteins. Many of the 48 human members of the largest family of transcription factors in metazoans have the unique property to be specifically activated by small lipophilic ligands i
作者: ZEST    時(shí)間: 2025-3-25 16:20
Genome-Wide Principles of Gene Regulation,ription factor binding sites that are under evolutionary control. However, only in combination with experimental data obtained by Big Biology projects like . such . approaches are effective. The rapidly increasing amount of ChIP-seq data on transcription factor locations and multiple histone modific
作者: STERN    時(shí)間: 2025-3-25 21:19
Chromatin Modifiers,, gene expression and development. Histone modifying enzymes, such as HATs, HDACs, KMT and lysine demethylases (KDMs), either add or remove post-translational modifications, such as acetylations and methylations, to histone proteins and in this way change the functional profile of the epigenome. The
作者: hair-bulb    時(shí)間: 2025-3-26 01:06
Epigenetics,nd 3D organization of the DNA. During development patterns of gene repression are established by both DNA methylation and histone modification. Histone methylation causes easily reversible local formation of heterochromatin, whereas DNA methylation mostly leads to stable long-term repression. Aberra
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作者: 沙發(fā)    時(shí)間: 2025-3-26 11:39
Regulatory Impact of Non-coding RNA,s giving rise to tens of thousands of ncRNAs. Not all of these transcripts are functional, however, many ncRNAs have regulatory specificity, ., some of them function similarly to proteins. miRNAs are small ncRNAs that regulate post-transcriptionally the expression of several thousand genes. They sha
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作者: 暫時(shí)過(guò)來(lái)    時(shí)間: 2025-3-27 06:33
Carsten Carlberg,Ferdinand Molnár time-dependant measurement of concentration while sparging a steady water batch allows to determine a VOC concentration in water irrespectively of the knowledge of the Henry constant which is dependant on temperature and on the analytical matrix (ionic strenght and organic contaminants dissolved in
作者: 踉蹌    時(shí)間: 2025-3-27 11:11
Carsten Carlberg,Ferdinand Molnároelectronic LC devices..Even besides the main application area of LC’s, namely displays, there has been a large and fruitful R&D activity aimed at the development of novel or advanced devices exploiting the peculiar properties of these materials. A number of sensors and optical modulators or switche
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Carsten Carlberg,Ferdinand Molnár time-dependant measurement of concentration while sparging a steady water batch allows to determine a VOC concentration in water irrespectively of the knowledge of the Henry constant which is dependant on temperature and on the analytical matrix (ionic strenght and organic contaminants dissolved in
作者: 抵押貸款    時(shí)間: 2025-3-28 03:46
Carsten Carlberg,Ferdinand Molnáris procedure allows to change the grating peak wavelength utilizing a single phase mask. A properly designed apparatus was described to write spatially and spectrally well separated grating arrays, distributed on a length of fiber, as well as arrays of adjacent gratings spectrally concatenated..Two
作者: Mingle    時(shí)間: 2025-3-28 06:27
phase. Results for h-Ig G adsorption indicates the relation between the surface mass and the frequency shift. The adsorption process does not bind covalently the molecules to the surface. In the case of a stable binding for the receptor to the surface is needed, a covalent immobilization is recomme
作者: 帶來(lái)    時(shí)間: 2025-3-28 11:54
overview on the present understanding of the mechanisms of gThis textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such
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作者: 四牛在彎曲    時(shí)間: 2025-3-28 20:29
Basal Transcriptional Machinery,s not a single defined nucleotide. The basal transcriptional machinery interacts . another multi-protein complex of co-activators, termed the Mediator complex, with a large variation of transcription factors. In parallel, the Mediator complex coordinates the action of co-activators and co-repressors, some of which are chromatin modifiers.
作者: synchronous    時(shí)間: 2025-3-29 02:39

作者: 感激小女    時(shí)間: 2025-3-29 05:30
Epigenetics, intra- and inter-chromosomal contacts and in this way to stabilize 3D complexes of chromatin loops. CTCF-mediated loops at several developmentally regulated loci provide a mechanistic explanation of genomic imprinting.
作者: 水槽    時(shí)間: 2025-3-29 09:47





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