標(biāo)題: Titlebook: Mechanisms of Gene Regulation; Carsten Carlberg,Ferdinand Molnár Textbook 20141st edition Springer Science+Business Media Dordrecht 2014 c [打印本頁] 作者: ACE313 時(shí)間: 2025-3-21 17:53
書目名稱Mechanisms of Gene Regulation影響因子(影響力)
書目名稱Mechanisms of Gene Regulation影響因子(影響力)學(xué)科排名
書目名稱Mechanisms of Gene Regulation網(wǎng)絡(luò)公開度
書目名稱Mechanisms of Gene Regulation網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Mechanisms of Gene Regulation被引頻次
書目名稱Mechanisms of Gene Regulation被引頻次學(xué)科排名
書目名稱Mechanisms of Gene Regulation年度引用
書目名稱Mechanisms of Gene Regulation年度引用學(xué)科排名
書目名稱Mechanisms of Gene Regulation讀者反饋
書目名稱Mechanisms of Gene Regulation讀者反饋學(xué)科排名
作者: 神圣將軍 時(shí)間: 2025-3-21 22:40 作者: Prostatism 時(shí)間: 2025-3-22 00:48 作者: 有發(fā)明天才 時(shí)間: 2025-3-22 08:09
Carsten Carlberg,Ferdinand Molnár gene expression is Ca2+/calmodulm dependent. We also demonstrate that hypoxia activates the extracellular-regulated kinase (ERK) and p38, but not JNK. Further, phosphorylation of ERK is essential for c-fos activation via SRE cis-element. Further characterization of nuclear signalling pathways provi作者: 臭了生氣 時(shí)間: 2025-3-22 10:16
Carsten Carlberg,Ferdinand Molnár strain distribution pattern (SDP). The SDP for hypoxic . is consistent with the hypothesis that parental strain differences are regulated by two genes. Cosegregation analysis suggest that the genetic control of . during hypoxia differs from the genes which control differential baseline .. Although 作者: 逃避系列單詞 時(shí)間: 2025-3-22 15:29 作者: BUOY 時(shí)間: 2025-3-22 18:45
Carsten Carlberg,Ferdinand Molnár gene expression is Ca2+/calmodulm dependent. We also demonstrate that hypoxia activates the extracellular-regulated kinase (ERK) and p38, but not JNK. Further, phosphorylation of ERK is essential for c-fos activation via SRE cis-element. Further characterization of nuclear signalling pathways provi作者: 演繹 時(shí)間: 2025-3-22 23:46 作者: maculated 時(shí)間: 2025-3-23 04:48 作者: goodwill 時(shí)間: 2025-3-23 06:11 作者: 微不足道 時(shí)間: 2025-3-23 13:42
Carsten Carlberg,Ferdinand Molnárunit, suggesting that heterodimerization is required for stable association within the nuclear compartment. Nuclear stabilization of the heterodimer might also explain the hypoxically increased total cellular ARNT levels observed in some of the cell lines examined.作者: Nebulous 時(shí)間: 2025-3-23 17:11
Carsten Carlberg,Ferdinand Molnárunit, suggesting that heterodimerization is required for stable association within the nuclear compartment. Nuclear stabilization of the heterodimer might also explain the hypoxically increased total cellular ARNT levels observed in some of the cell lines examined.作者: BAIL 時(shí)間: 2025-3-23 21:21 作者: sphincter 時(shí)間: 2025-3-23 22:56
form of this disease that can markedly reduce their survival and quality of life. The high level of drug resistance exhibited by these organisms makes ffective chemotherapy difficult to achieve and maintain. The response to these drugs is bacteriostatic rather than bactericidal and the disease recu作者: 高調(diào) 時(shí)間: 2025-3-24 06:18 作者: encyclopedia 時(shí)間: 2025-3-24 10:25 作者: 鳴叫 時(shí)間: 2025-3-24 11:19 作者: lethargy 時(shí)間: 2025-3-24 15:07 作者: 直覺沒有 時(shí)間: 2025-3-24 21:09 作者: 斗志 時(shí)間: 2025-3-24 23:36 作者: Injunction 時(shí)間: 2025-3-25 05:49
Switching Genes on and off: The Example of Nuclear Receptorsle of nuclear receptors..In this Chapter, we will discuss principles of nuclear receptor signaling and the subdivision of the nuclear receptor superfamily into three sub-classes. Then we will have a look on the different molecular interactions of nuclear receptors. Furthermore, the physiological act作者: 上腭 時(shí)間: 2025-3-25 08:07
Mapping the Genomeeracting nuclear proteins and may not always directly contact DNA. This new insight has also consequences on the question, which transcription factor is assigned to the regulation of which gene, i.e. not always the approach applies that sites in rather close vicinity to TSS regions are the main regi作者: 舔食 時(shí)間: 2025-3-25 11:53 作者: 徹底檢查 時(shí)間: 2025-3-25 15:51 作者: 講個(gè)故事逗他 時(shí)間: 2025-3-25 20:04 作者: Bridle 時(shí)間: 2025-3-26 02:05
Chromatin Remodelingtate to an active state. Pioneer transcription factors are the first that bind a closed promoter and play an important role in providing access to other sequence-specific transcription factors. Furthermore, regulatory genomic regions are now understood as dynamic structures, showing high turnover of作者: fulmination 時(shí)間: 2025-3-26 05:26 作者: Aprope 時(shí)間: 2025-3-26 11:35
Regulatory RNA or more proteins into a spatial proximity or iii) as guides to recruit proteins, such as chromatin modifying enzymes, to genomic DNA. A special variant of long ncRNAs are enhancer RNAs (eRNAs), which are produced bidirectionally at enhancer regions, when the latter interact with promoter regions..m作者: CHARM 時(shí)間: 2025-3-26 13:41 作者: 刺耳 時(shí)間: 2025-3-26 17:46
tion of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is t978-94-007-7905-1作者: 桉樹 時(shí)間: 2025-3-26 23:26
Springer Science+Business Media Dordrecht 2014作者: promote 時(shí)間: 2025-3-27 05:05 作者: OVER 時(shí)間: 2025-3-27 06:15
http://image.papertrans.cn/m/image/628720.jpg作者: CONE 時(shí)間: 2025-3-27 09:53
https://doi.org/10.1007/978-94-007-7905-1chromatin; gene regulation; protein structure; signal transduction; transcription factors; gene expressio作者: 紅潤(rùn) 時(shí)間: 2025-3-27 15:00 作者: 不愛防注射 時(shí)間: 2025-3-27 20:19
The Impact of Chromatingenome of 2?×?3.26?billion?bp, lines up to a length of some 2?m, i.e. 200,000 times the diameter of an average mammalian nucleus. Packing DNA inside the nucleus therefore imposes tremendous organizational challenges. The highly condensed packing of genomic DNA is achieved through i) wrapping it arou作者: MAZE 時(shí)間: 2025-3-27 22:40
The Basal Transcriptional Machineryiption is controlled. Pol II is the core of the basal transcriptional machinery, which contains a large number of general transcription factors, many of them are summarized as the TFIID complex. Via another multi-protein complex of co-activators, termed Mediator, the basal transcriptional machinery 作者: HAVOC 時(shí)間: 2025-3-28 03:33
Transcription Factorsnmental pertubations. In humans there are approximately 1,900 site-specific DNA-binding transcription factors. The most characteristic domain of a transcription factor is its DBD, but they also contain domains for dimerization and for contacts with co-factors..Only a small subset of these 1,900 tran作者: Tremor 時(shí)間: 2025-3-28 09:53
Linking Signal Transduction and Gene Regulationscades, which mostly start with an extracellular signaling molecule and end with an activated transcription factor. Latent transcription factors, such as SMAD, STAT, NFKB and others, are central to these pathways, as they are activated through different mechanisms of their translocation from the cyt作者: CRUE 時(shí)間: 2025-3-28 12:52
Switching Genes on and off: The Example of Nuclear Receptorss in the size of cholesterol (approx.?400?Da). Some of these ligands are known as important endocrine hormones, such as estradiol and testosterone, while others are metabolites of dietary compounds, such as fatty acids and cholesterol. Both types of molecules are of large physiological impact in hea作者: LATE 時(shí)間: 2025-3-28 14:35 作者: 補(bǔ)充 時(shí)間: 2025-3-28 20:30
Chromatin Modifierscal processes in the context of development and cellular responses. The present understanding of the function of histone modifications is summarized in the histone code model..There are two pairs of chromatin modifying enzymes, each with antagonizing activity: histone acetylases and deacetylases and作者: HOWL 時(shí)間: 2025-3-29 02:48
Genomic Imprintinghat insulate genes located in one chromatin domain from promiscuous regulation by enhancers or silencers in neighboring domains. The genome regulator CTCF has tens of thousands DNA-binding sites in human cells, many of which are located in intergenic regions, such as insulators. Most of these sites 作者: Mundane 時(shí)間: 2025-3-29 05:35 作者: Hypomania 時(shí)間: 2025-3-29 08:53
Chromatin Remodelingo access these sequences. This is controlled by histone modifications (see Chap.?8), DNA methylation (see Chaps.?9 and 10) and ATP-dependent chromatin remodeling. Chromatin remodeling factors are multi-protein complexes that use the energy of ATP hydrolysis to remodel or remove nucleosomes, in order作者: Glycogen 時(shí)間: 2025-3-29 14:26 作者: follicular-unit 時(shí)間: 2025-3-29 18:33
Regulatory RNAs giving rise to thousands of non-coding RNAs (ncRNAs). Not all of these transcripts are functional, however, many ncRNAs have regulatory specificity. Micro RNAs (miRNAs) are small ncRNAs that post-transcriptionally regulate the expression of thousands of genes. After the identification of the exist作者: 闖入 時(shí)間: 2025-3-29 19:54 作者: defenses 時(shí)間: 2025-3-30 02:47
Carsten Carlberg,Ferdinand Molnár the body. The pathways over which peripheral chemoreccptor signals are transmitted to respiratory muscles arc well established. However, the intracellular pathways that transmit hypoxic stimulus to gene activation are just being identified. Using anti-sense c-fos strategy, we have shown that c-fos 作者: 采納 時(shí)間: 2025-3-30 05:13 作者: 嬰兒 時(shí)間: 2025-3-30 08:35 作者: Breach 時(shí)間: 2025-3-30 15:07 作者: 金哥占卜者 時(shí)間: 2025-3-30 17:38 作者: 就職 時(shí)間: 2025-3-31 00:31
Carsten Carlberg,Ferdinand Molnárbon receptor nuclear translocator (ARNT). Whereas hypoxia prevents ubiquitination and proteasomal degradation of HIF-1α ARNT expression is thought to be oxygen-independent. We and others previously showed that ARNT is indispensable for HIF-1 DNA-binding and transactivation function. To examine the r作者: FLASK 時(shí)間: 2025-3-31 03:14 作者: GLARE 時(shí)間: 2025-3-31 06:26
Carsten Carlberg,Ferdinand Molnárbon receptor nuclear translocator (ARNT). Whereas hypoxia prevents ubiquitination and proteasomal degradation of HIF-1α ARNT expression is thought to be oxygen-independent. We and others previously showed that ARNT is indispensable for HIF-1 DNA-binding and transactivation function. To examine the r作者: Aggregate 時(shí)間: 2025-3-31 11:07
Carsten Carlberg,Ferdinand Molnárbon receptor nuclear translocator (ARNT). Whereas hypoxia prevents ubiquitination and proteasomal degradation of HIF-1α ARNT expression is thought to be oxygen-independent. We and others previously showed that ARNT is indispensable for HIF-1 DNA-binding and transactivation function. To examine the r
