標(biāo)題: Titlebook: Mechanisms of Drug Resistance in Cancer Therapy; Mario Mandalà,Emanuela Romano Book 2018 Springer Nature Switzerland AG 2018 Drug resistan [打印本頁] 作者: 非決定性 時間: 2025-3-21 18:06
書目名稱Mechanisms of Drug Resistance in Cancer Therapy影響因子(影響力)
書目名稱Mechanisms of Drug Resistance in Cancer Therapy影響因子(影響力)學(xué)科排名
書目名稱Mechanisms of Drug Resistance in Cancer Therapy網(wǎng)絡(luò)公開度
書目名稱Mechanisms of Drug Resistance in Cancer Therapy網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Mechanisms of Drug Resistance in Cancer Therapy被引頻次
書目名稱Mechanisms of Drug Resistance in Cancer Therapy被引頻次學(xué)科排名
書目名稱Mechanisms of Drug Resistance in Cancer Therapy年度引用
書目名稱Mechanisms of Drug Resistance in Cancer Therapy年度引用學(xué)科排名
書目名稱Mechanisms of Drug Resistance in Cancer Therapy讀者反饋
書目名稱Mechanisms of Drug Resistance in Cancer Therapy讀者反饋學(xué)科排名
作者: 易達(dá)到 時間: 2025-3-21 20:17
Benedetta Colmegna,Lavinia Morosi,Maurizio D’Incalciss of this methodology is demonstrated through the design of an operational amplifier. This methodology consists of the following iterative steps: description of the circuit functionality at a high level of abstraction using signal flow graphs; equivalent transformations and modifications of the gra作者: 小口啜飲 時間: 2025-3-22 02:24
Huifang Tang,Gongda Xuess of this methodology is demonstrated through the design of an operational amplifier. This methodology consists of the following iterative steps: description of the circuit functionality at a high level of abstraction using signal flow graphs; equivalent transformations and modifications of the gra作者: delta-waves 時間: 2025-3-22 04:32 作者: nephritis 時間: 2025-3-22 10:18 作者: 卜聞 時間: 2025-3-22 15:14 作者: NUDGE 時間: 2025-3-22 17:10 作者: narcissism 時間: 2025-3-22 22:56 作者: disrupt 時間: 2025-3-23 03:03
Major Physiological Signaling Pathways in the Regulation of Cell Proliferation and Survival,ce between cell growth and death is achieved through orchestrated signal transduction pathways mediated by complex functional interactions between signaling axes, among which, PI3K/Akt and Ras/MAPK as well as JAK/STAT play a dominant role in promoting cell proliferation, differentiation, and surviva作者: 圓錐 時間: 2025-3-23 07:11 作者: 緯線 時間: 2025-3-23 11:36
Mechanisms of Resistance to Target Therapies in Non-small Cell Lung Cancer,ung adenocarcinoma, like . mutations or . rearrangements, has changed the treatment landscape while improving the prognosis of lung cancer patients. Inevitably, virtually all patients initially treated with targeted therapies develop resistance because of the emergence of an insensitive cellular pop作者: GEN 時間: 2025-3-23 16:23
Mechanisms of Drug Resistance in Melanoma,rgeted small-molecule inhibitors and immunotherapy has revolutionised the care and improved the overall survival of these patients. Therapies targeting BRAF and MEK to block the mitogen-activated protein kinase (MAPK) pathway were the first to show unprecedented clinical responses. Following these e作者: sclera 時間: 2025-3-23 21:26 作者: Negligible 時間: 2025-3-23 23:18 作者: –LOUS 時間: 2025-3-24 04:30 作者: 分發(fā) 時間: 2025-3-24 07:57
Targeting DNA Repair,orms of genomic instability arising from many different pathways, such as DNA damage from endogenous and exogenous sources, centrosome amplification, telomere damage, and epigenetic modifications. DNA-repair pathways can enable tumor cells to survive DNA damage. The failure to respond to DNA damage 作者: venous-leak 時間: 2025-3-24 13:45 作者: 約會 時間: 2025-3-24 15:55 作者: Radiculopathy 時間: 2025-3-24 19:52 作者: Etymology 時間: 2025-3-24 23:24 作者: Immobilize 時間: 2025-3-25 06:10
Mechanisms of Resistance in Multiple Myeloma,medullary sites. Multi-modality approaches including “novel agents,” traditional chemotherapy, and/or stem cell transplantation are used in MM therapy. Drug resistance, however, ultimately develops and the disease remains incurable for the vast majority of patients. In this chapter, we review both t作者: enormous 時間: 2025-3-25 09:33 作者: CYT 時間: 2025-3-25 14:15
Mario Mandalà,Emanuela RomanoGives an updated overview on the possible reasons of failure of new and promising therapeutic opportunities.Provides extensive discussions of issues including pharmacodynamic and pharmacokinetic mecha作者: 魔鬼在游行 時間: 2025-3-25 16:00
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/m/image/628714.jpg作者: 相同 時間: 2025-3-25 21:46
https://doi.org/10.1007/978-3-030-10507-5Drug resistance; Drug mechanisms; Targeted therapy; Immunotherapy; Chemotherapy; antibacterial drug resis作者: Canvas 時間: 2025-3-26 01:00
Springer Nature Switzerland AG 2018作者: Incisor 時間: 2025-3-26 06:31 作者: 反復(fù)無常 時間: 2025-3-26 12:01
Book 2018 rational therapeutic drug combinations and the use of predictive and prognostic biomarkers to enable patient stratification and tailor treatments. It offers to the readers an updated overview on the possible reasons of failure of new and promising therapeutic opportunities..作者: 瑣事 時間: 2025-3-26 13:25
Major Physiological Signaling Pathways in the Regulation of Cell Proliferation and Survival,research have suggested that the intrinsic pro-survival signaling crosstalk is the driving force in acquired resistance to a targeted therapy, which may be abolished by interfering with the cross-reacting network.作者: 禁令 時間: 2025-3-26 20:24 作者: Banister 時間: 2025-3-26 21:36 作者: 擔(dān)憂 時間: 2025-3-27 01:14
Targeting DNA Repair,anding of the molecular mechanisms through which the DNA damage response (DDR) operates, in combination with the elucidation of the genetic interactions between DDR pathways and other cell pathways, will provide therapeutic opportunities for the personalized medicine of cancer.作者: 合并 時間: 2025-3-27 06:44
Book 2018 rational therapeutic drug combinations and the use of predictive and prognostic biomarkers to enable patient stratification and tailor treatments. It offers to the readers an updated overview on the possible reasons of failure of new and promising therapeutic opportunities..作者: 有惡臭 時間: 2025-3-27 12:11
0171-2004 f issues including pharmacodynamic and pharmacokinetic mecha.A major objective of this book is to reveal unprecedented opportunities to understand and overcome drug resistance through the clinical assessment of rational therapeutic drug combinations and the use of predictive and prognostic biomarker作者: Dawdle 時間: 2025-3-27 15:36
Molecular and Pharmacological Mechanisms of Drug Resistance:An Evolving Paradigm,asons and inefficient and heterogeneous tumor drug distribution, related to a deficient vascularization and high interstitial pressure. Finally, resistance can be related to the activation of anti-apoptotic and cell survival pathways by cancer cells and often enhanced by tumor microenvironment.作者: GROSS 時間: 2025-3-27 18:30
Mechanisms of Resistance to Targeted Therapies in Chronic Myeloid Leukemia,been identified, ranging from BCR-ABL1 kinase domain mutations to lack of adherence to therapy. In this review, we briefly summarize the clinical efficacy of approved TKIs and describe the main mechanisms of TKI resistance.作者: 熒光 時間: 2025-3-28 00:28 作者: 改良 時間: 2025-3-28 05:08 作者: habile 時間: 2025-3-28 09:57
Mechanisms of Resistance to Target Therapies in Non-small Cell Lung Cancer,transition). These basic mechanisms are informing the development of novel therapeutic strategies to overcome resistance in the clinic. Novel-generation molecules include osimertinib, for EGFR-T790M-positive patients, and new ALK-TKIs. Nevertheless, the possible concomitant presence of multiple resi作者: 畫布 時間: 2025-3-28 13:30 作者: hemophilia 時間: 2025-3-28 16:44
Plasticity of Resistance and Sensitivity to Anti-Epidermal Growth Factor Receptor Inhibitors in Mets are rarer in this disease. Even though some of these molecular abnormalities make genes acting as drivers of cancer progression, translation of this recognition for therapeutic purposes is still limited, encompassing only as standard of care the exclusion of .-mutated cancers for better selecting 作者: accessory 時間: 2025-3-28 19:19 作者: 感情脆弱 時間: 2025-3-29 00:50
Mechanism of Resistance in Gastrointestinal Stromal Tumors, in which the interaction between the drug and the receptor happens. Other mechanisms causing drug resistance have been investigated, indicating that many aspects need to be still explicated and fully understood in order to define a strategy able to fight definitively GIST growth.作者: 指令 時間: 2025-3-29 03:32 作者: aerial 時間: 2025-3-29 07:36
Mechanisms of Resistance in Multiple Myeloma,allenge our current understanding of treatment responses. Thirdly, the success of MM “novel agents” provides exemplary evidence for the impact of therapies that target the immune and non-immune microenvironment. Fourthly, the rapid pace of drug approvals for MM creates an impetus for development of 作者: Mosaic 時間: 2025-3-29 11:27 作者: affinity 時間: 2025-3-29 16:46
e same approach is used to design clamps and limiting circuits which improve the performance of the amplifier outside of its linear operating region, such as slew rate enhancement, output short circuit current limitation, and input overload recovery.978-1-4419-5437-4978-1-4020-2517-4Series ISSN 0893-3405 作者: 我就不公正 時間: 2025-3-29 22:04
Benedetta Colmegna,Lavinia Morosi,Maurizio D’Incalcie same approach is used to design clamps and limiting circuits which improve the performance of the amplifier outside of its linear operating region, such as slew rate enhancement, output short circuit current limitation, and input overload recovery.978-1-4419-5437-4978-1-4020-2517-4Series ISSN 0893-3405 作者: erythema 時間: 2025-3-30 02:27 作者: 不透明 時間: 2025-3-30 07:17
Diego O. Croci,Santiago P. Mendez-Huergo,Juan P. Cerliani,Gabriel A. Rabinoviche same approach is used to design clamps and limiting circuits which improve the performance of the amplifier outside of its linear operating region, such as slew rate enhancement, output short circuit current limitation, and input overload recovery.978-1-4419-5437-4978-1-4020-2517-4Series ISSN 0893-3405 作者: definition 時間: 2025-3-30 11:40 作者: definition 時間: 2025-3-30 13:15 作者: 相同 時間: 2025-3-30 18:02 作者: 借喻 時間: 2025-3-30 22:08
Federico Lussana,Tamara Intermesoli,Paola Stefanoni,Alessandro Rambaldi作者: Overthrow 時間: 2025-3-31 00:56
larity, calm, and competence—perhaps even brilliance, if you can train yourself toconvert the free energy of your fear into controlled performance. Tierney repeatedly warns his introvert readers that they risk presentation fiasco if they skip, skimp, or change the order of any of the ten steps he prescribes f978-1-4842-1089-5978-1-4842-1088-8作者: VEIL 時間: 2025-3-31 05:20
