標(biāo)題: Titlebook: Mechanisms in B-Cell Neoplasia 1990; Workshop 1990 at the Michael Potter,Fritz Melchers Book 1990 The Editor(s) (if applicable) and The Aut [打印本頁(yè)] 作者: 出租車 時(shí)間: 2025-3-21 19:26
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作者: 忘恩負(fù)義的人 時(shí)間: 2025-3-21 23:34
gered by lightning discharge.Presents a successful simulatio.This book presents the first simultaneous detection of neutrons and positrons after a terrestrial gamma-ray flash (TGF), a highest-energy transient phenomenon on the earth, triggered by a lightning discharge, based on innovative ground-bas作者: 煩憂 時(shí)間: 2025-3-22 03:46 作者: MOTIF 時(shí)間: 2025-3-22 05:49
S. Suematsu,M. Hibi,T. Sugita,M. Saito,M. Murakami,T. Matsusaka,T. Matsuda,T. Hirano,T. Taga,T. Kishof voluntary donation by citizens, and gradually moved toward to institutionalization, standardization and legalization channel. The major breakthrough in citizen organ donation has not only brought great well-being to mankind, but also brought serious ethical challenges. However, the human organ pr作者: 泥土謙卑 時(shí)間: 2025-3-22 12:12 作者: Popcorn 時(shí)間: 2025-3-22 14:56 作者: 較早 時(shí)間: 2025-3-22 17:23 作者: Precursor 時(shí)間: 2025-3-22 22:10 作者: 大門(mén)在匯總 時(shí)間: 2025-3-23 05:25 作者: CHOP 時(shí)間: 2025-3-23 05:57
Koichi Nakajima,Randolph Wallcation of novel therapeutics. Genetic determinants, protein products, signaling molecules, potential drug targets, or novel/repurposed drugs identified in genomic, proteomic, or pharmaceutical studies are frequently evaluated in vivo using appropriate animal models. Essentially such models closely r作者: declamation 時(shí)間: 2025-3-23 12:33
Clay B. Siegall,David J. FitzGerald,Ira Pastanatic phase. Quality and timely surgery is the key intervention for both the curative and the palliative setting, providing one of the largest benefits on the survival outcomes. However, patients with OC, at all stages, benefit of a number of pharmacological treatments, both chemotherapy and targeted作者: 蝕刻術(shù) 時(shí)間: 2025-3-23 16:16 作者: cushion 時(shí)間: 2025-3-23 19:50 作者: visceral-fat 時(shí)間: 2025-3-24 01:29
Richard G. Hoover,Sheryl Roman,Jonni S. Moore,Christine Darby,Susan Müllero for a new class of nonautonomous optimal control problems This book is devoted to the study of classes of optimal control problems arising in economic growth theory, related to the Robinson–Solow–Srinivasan (RSS) model. The model was introduced in the 1960s by economists Joan Robinson, Robert Solo作者: Melanoma 時(shí)間: 2025-3-24 03:57 作者: 清澈 時(shí)間: 2025-3-24 08:04 作者: Encumber 時(shí)間: 2025-3-24 14:26
S. Silva,H. Sugiyama,M. Babonits,F. Wiener,G. Kleinon local communities and ecology. The increase in anti-tourism events around the world is a significant indicator of the effects of overtourism on communities. The underlying reason for the problem is mainly based on the decisions which were taken in a hurry, without proper evaluation, consideration作者: 巧思 時(shí)間: 2025-3-24 17:53
F. Wiener,S. Silva,H. Sugiyama,M. Babonits,H. Axelson,P. Chinmay,G. Kleinst and most fiercely debated issues across the world. In the last decade, overtourism has become a buzzword and a social movement in tourism, gaining a lot of media attention. Effective, efficient, and innovative solutions to address the problem of overtourism at various destinations have been calle作者: arabesque 時(shí)間: 2025-3-24 21:14 作者: GULP 時(shí)間: 2025-3-25 00:53
U. R. Rapp,J. Troppmair,M. Carroll,S. May production, consumption behavior, and business ecosystem. Primarily interaction transformed scattered and unorganized travel into orderly and organized tourism. It also assisted organized tourism to spread amid mass milieu beyond the elitist edge in the post-1950s. Further, it played a crucial role作者: 字形刻痕 時(shí)間: 2025-3-25 06:21
IL-6 as a Growth Factor for Human Multiple Myeloma Cells - A Short Overviewh-and differentiation factor signalling. The activation of resting B-cells, and their subsequent growth and/or differentiation, have thus been found to be regulated by multiple, alternative cytokines acting in concert to ensure a fine-tuned control of the process. Malignant B-cells, best exemplified作者: 向下 時(shí)間: 2025-3-25 08:52
Interleukin 6 (IL-6) and Its Receptor (IL-6R) in Myeloma/Plasmacytomaproducing cells (Hirano . 1986). However, subsequent studies with recombinant molecules revealed that IL-6 has a wide variety of biological functions on various tissues and cells (Kishimoto 1989). As shown in Fig. 1, IL-6 acts not only on B cells but also on hematopoietic progenitors and hepatocytes作者: Cpr951 時(shí)間: 2025-3-25 12:28
Interleukin-6 is a Major Myeloma Cell Growth Factor In Vitro and In Vivo Especially in Patients withls that destroy the bone tissue. This disease is lethal in any case and little therapeutic progress has been achieved these last 20 years. Although myeloma cells poorly proliferate in vivo, the in vivo labelling index of the myeloma cells (LI = percentage of myeloma cells in the S-phase) constitutes作者: arabesque 時(shí)間: 2025-3-25 17:40
Macrophages as an Important Source of Paracrine IL6 in Myeloma Bone Marrowm patients with aggressive clinical disease (.). Although it has been documented that myeloma cells have large numbers of IL-6 receptors and that both the bone marrow and serum of patients with active myeloma contain increased levels of IL6, the source(s) and regulation of IL6 levels are not fully u作者: Preamble 時(shí)間: 2025-3-25 22:46
Retroviral-Mediated Transfer of Interleukin-6 Into Hematopoietic Cells of Mice Results in a Syndromeection or injury (Kishimoto 1989). IL-6 has prominent actions on cells of the immune system, including stimuiation of immunoglobulin synthesis by activated B-cells and differentiation of cytotoxic T-cells. In addition, it induces hematopoietic stem cells to enter cell cycle, committed myeloid progen作者: SNEER 時(shí)間: 2025-3-26 03:51 作者: 尊嚴(yán) 時(shí)間: 2025-3-26 06:31 作者: 魅力 時(shí)間: 2025-3-26 10:18 作者: V洗浴 時(shí)間: 2025-3-26 13:15
In Vitro Culture of a Primary Plasmacytoma that has Retained Its Dependence on Pristane Conditioned pentadecane), induces the formation of plasmacytomas (PCT) that arise in the peritoneal inflammatory tissues evoked by these agents (Potter and MacCardle 1964). The paraffin oils and pristane are known to induce the formation of a chronic oil granulomatous (OG) tissue on peritoneal surfaces (Potter 作者: Neonatal 時(shí)間: 2025-3-26 17:43
Modulation of Growth and Differentiation of Murine Myeloma Cells by Immunoglobulin Binding Factors(reviewed by Fridman 1987 ). A variety of soluble factors, that bind all classes of immunoglobulins in an isotype-specific manner, have been described and can augment or suppress B cell growth and differentiation in an isotype-specific fashion (Fridman 1987). Evidence has been presented that certain作者: GLADE 時(shí)間: 2025-3-27 00:00 作者: 迎合 時(shí)間: 2025-3-27 01:29
The Activity of an , Retrovirus in Fibroblast Cell Lines and in Lymphocytesconditions both may synergize in that process. The first indication of the interaction of these two oncogenes was the experiments of Potter et al (1973) in which it was found that infection of pristane-primed mice with Abelson murine leukemia virus (A-MuLV) greatly decreased the latent period for pl作者: 混合,攙雜 時(shí)間: 2025-3-27 08:15 作者: Derogate 時(shí)間: 2025-3-27 12:41
Mouse Plasmacytoma Associated (MPC) T(15;16) Translocation Occurs Repeatedly in New MPC Induction Sy translocations. I do not intend to describe how successfully the whole story developed in the hands of molecular biologists. From the cytogenetic point of view, however, one intriguing question has remained unsolved (illustrated in Fig. 1).作者: Devastate 時(shí)間: 2025-3-27 15:35 作者: forbid 時(shí)間: 2025-3-27 19:06
Role of ,-1 Protein Kinase in IL-3 and GM-CSF-Mediated Signal Transductiononcogene by N-terminal fusion, truncation, or by site-specific mutation (Heidecker et al., 1990). When activated forms of the .-1 gene were expressed in E. coli, the purified protein had kinase activity . and induced DNA synthesis as well as morphological transformation upon microinjection into quie作者: 不感興趣 時(shí)間: 2025-3-28 01:17
Current Topics in Microbiology and Immunologyhttp://image.papertrans.cn/m/image/628687.jpg作者: 皮薩 時(shí)間: 2025-3-28 02:48 作者: 油膏 時(shí)間: 2025-3-28 06:43
Mechanisms in B-Cell Neoplasia 1990978-3-642-75889-8Series ISSN 0070-217X Series E-ISSN 2196-9965 作者: 壓碎 時(shí)間: 2025-3-28 11:07 作者: 放縱 時(shí)間: 2025-3-28 14:43
A Monoclonal Antibody Specific for the Murine IL-6-Receptor Inhibits the Growth of a Mouse PlasmacytAntibodies specific for the human IL-6 receptor have been obtained by immunization with cells transfected with the cDNA for the 80kDa protein that was identified by Yamasaki as the human IL-6 receptor (Yamasaki, 1988; Hirata, 1989)). Unfortunately, similar reagents do not yet exist for the mouse IL-6 receptor.作者: PHON 時(shí)間: 2025-3-28 20:04
https://doi.org/10.1007/978-3-642-75889-8Burkitt‘s Lymphoma; Lymphome; Myelome; Neoplasie; Onkologie; Tumoren; oncology; plasma cells; tumorigenesis; 作者: 一小塊 時(shí)間: 2025-3-28 23:15 作者: Herd-Immunity 時(shí)間: 2025-3-29 06:03
Role of ,-1 Protein Kinase in IL-3 and GM-CSF-Mediated Signal Transductionin E. coli, the purified protein had kinase activity . and induced DNA synthesis as well as morphological transformation upon microinjection into quiescent NIH 3T3 cells (Smith et al., 1990). Thus, activated .-1 is an intracellular mitogen.作者: 浮雕寶石 時(shí)間: 2025-3-29 10:15 作者: GLEAN 時(shí)間: 2025-3-29 13:30 作者: 夸張 時(shí)間: 2025-3-29 18:22 作者: Merited 時(shí)間: 2025-3-29 20:05 作者: 傾聽(tīng) 時(shí)間: 2025-3-30 03:45 作者: 使害怕 時(shí)間: 2025-3-30 06:30 作者: padding 時(shí)間: 2025-3-30 11:37
In Vitro Culture of a Primary Plasmacytoma that has Retained Its Dependence on Pristane Conditioned s and become fixed to peritoneal surfaces (Anderson et al 1985). The OG tissue is vascularized by angiogenesis from mesenteric blood vessels and covered by mesothelium. In addition, the OG tissue contains a rich supportive stroma of fibroblasts and reticular fibroblasts.作者: 系列 時(shí)間: 2025-3-30 12:31
Plasmacytoma Induction in BALB/c6;15 → DBA/2 Chimeras induction, suggesting that resistance is under the control of genes that express dominancy, and susceptibility may represent the recesive allele, (Potter, 1984). The genes controlling susceptibility vs resistance have not been defined yet.作者: 游行 時(shí)間: 2025-3-30 17:33 作者: 飲料 時(shí)間: 2025-3-30 21:06 作者: delusion 時(shí)間: 2025-3-31 03:00 作者: 執(zhí)拗 時(shí)間: 2025-3-31 08:11
Modulation of Growth and Differentiation of Murine Myeloma Cells by Immunoglobulin Binding FactorsFc receptors, or by T cell blasts induced with IgA, have been described and depending upon the circumstances, can mediate either IgA-specific help or suppression (Adachi 1984; Kiyono 1985; Yodoi 1983).作者: landfill 時(shí)間: 2025-3-31 12:09 作者: 泛濫 時(shí)間: 2025-3-31 16:08 作者: exclusice 時(shí)間: 2025-3-31 20:16
B. Klein,X. G. Zhang,M. Jourdan,M. Portier,R. Batailleplants to pathogens, different approaches have been developed that interrogates the system at varying levels of disease infection. These approaches are generically called “omics” approaches that enable the study of plant systems at the genome, transcriptome, proteome, and metabolome levels. The adve作者: 向宇宙 時(shí)間: 2025-3-31 21:53 作者: configuration 時(shí)間: 2025-4-1 05:41
D. Emilie,M. Peuchmaur,P. Galanaud inherent issues of total weight flexibility and pseudo-efficiency. In this study, we have presented an approach for efficiency assessment of retail stores through peer evaluation using the cross-efficiency models of Data Envelopment Analysis (DEA) to address these issues. The study also identifies 作者: 含沙射影 時(shí)間: 2025-4-1 08:17
Koichi Nakajima,Randolph Wallodified or induced in vivo models are used to unravel the systemic molecular cross-talk, metabolic networks, and interactome in obesity related cancers such as gastric cancer, liver cancer, pancreatic cancer, colon cancer, prostate cancer, breast cancer, and ovarian cancer among others. This chapter作者: Negotiate 時(shí)間: 2025-4-1 12:33 作者: 殘酷的地方 時(shí)間: 2025-4-1 17:30
