標(biāo)題: Titlebook: Macropinocytosis; Functions and Mechan Cosimo Commisso Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusive license t [打印本頁(yè)] 作者: Annihilate 時(shí)間: 2025-3-21 16:25
書(shū)目名稱Macropinocytosis影響因子(影響力)
作者: 欄桿 時(shí)間: 2025-3-22 00:13
Macropinocytosis978-3-030-94004-1Series ISSN 0306-0225 Series E-ISSN 2542-8810 作者: 滴注 時(shí)間: 2025-3-22 01:04 作者: excrete 時(shí)間: 2025-3-22 06:30 作者: tympanometry 時(shí)間: 2025-3-22 11:58 作者: archetype 時(shí)間: 2025-3-22 14:46
Functional Diversity of Macropinocytosisn be exploited to develop novel therapeutic targets. In this chapter, we discuss the different molecular mechanisms that initiate the process of macropinocytosis with special emphasis on proteins involved and their diversified role in different cell types.作者: 背叛者 時(shí)間: 2025-3-22 17:12 作者: ACTIN 時(shí)間: 2025-3-23 00:25 作者: 顯而易見(jiàn) 時(shí)間: 2025-3-23 02:21 作者: 神圣將軍 時(shí)間: 2025-3-23 07:33
Signaling Pathways that Regulate Macropinocytosis in Mammalian Cellscluding several nutrient-sensing and developmental signaling pathways. Many of these signaling pathways have proto-oncogenic properties, and their dysregulation drives the high macropinocytic activity that is commonly observed in cancer cells. These regulatory principles illustrate how macropinocyto作者: Assault 時(shí)間: 2025-3-23 11:20
Wnt, GSK3, and Macropinocytosisggering of Pak1 and the actin machinery is the inhibition of GSK3. Striking lysosomal acidification, which requires macropinocytosis, is induced by GSK3 chemical inhibitors or Wnt protein. Wnt-induced macropinocytosis requires the ESCRT machinery that forms MVBs. In cancer cells, mutations in the tu作者: 吸氣 時(shí)間: 2025-3-23 14:53 作者: Aggressive 時(shí)間: 2025-3-23 20:09 作者: machination 時(shí)間: 2025-3-23 23:35
embers Ms. Helga Ballmann, Ms. Beate Gobel, Ms. Monika Kohl, Ms. Sylvia Matyssek, Ms. Doris Schmitz-Braunstein, Ms. Utta-Barbara Stegemann. Mr. Jochen Heidt and978-3-662-12360-7978-3-662-12358-4Series ISSN 0067-0022 作者: Hdl348 時(shí)間: 2025-3-24 04:33
embers Ms. Helga Ballmann, Ms. Beate Gobel, Ms. Monika Kohl, Ms. Sylvia Matyssek, Ms. Doris Schmitz-Braunstein, Ms. Utta-Barbara Stegemann. Mr. Jochen Heidt and978-3-662-12360-7978-3-662-12358-4Series ISSN 0067-0022 作者: 偏見(jiàn) 時(shí)間: 2025-3-24 08:41 作者: athlete’s-foot 時(shí)間: 2025-3-24 13:20 作者: Organonitrile 時(shí)間: 2025-3-24 15:39 作者: Eosinophils 時(shí)間: 2025-3-24 19:07 作者: 感情脆弱 時(shí)間: 2025-3-24 23:21 作者: 要控制 時(shí)間: 2025-3-25 03:46 作者: 可觸知 時(shí)間: 2025-3-25 08:03
KRASG12R-Independent Macropinocytosis in Pancreatic Cancers have underscored how little we understand about the activation and regulation of this metabolic process. Therefore, this review seeks to highlight the differences in macropinocytosis regulation in the two cellular subtypes while also highlighting the features that make the KRAS. mutant atypical.作者: 稀釋前 時(shí)間: 2025-3-25 15:39
Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathwayser malignancy. Macropinocytic uptake can be induced in cancer cells by different stress stimuli, acting as an adaptive mechanism for the cells to resist stresses in the tumor milieu. Here, we review the cellular stresses that are known to promote macropinocytosis, as well as the underlying molecular mechanisms that drive this process.作者: Cardiac-Output 時(shí)間: 2025-3-25 18:58
Macropinocytosis in Phagocyte Function and Immunityve macropinocytosis and its role in the maintenance of immunity. Functions previously attributed to macropinocytosis, including antigen presentation and immune surveillance, will be revisited in light of recent revelations and emerging concepts will be highlighted.作者: anaerobic 時(shí)間: 2025-3-25 21:35 作者: SHOCK 時(shí)間: 2025-3-26 03:35
astrophysics, and their border fields. It is devoted to the recording, summarizing, and indexing of the relevant publications throughout the world. Astronomy and Astrophysics Abstracts is prepared by a special department of the Astronomisches Rechen-Institut under the auspices of the International A作者: Prostatism 時(shí)間: 2025-3-26 04:42 作者: Chagrin 時(shí)間: 2025-3-26 11:38 作者: tendinitis 時(shí)間: 2025-3-26 12:53
Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathwaysytic vesicles known as macropinosomes. In addition to other functions, this uptake pathway supports cancer cell metabolism through the uptake of nutrients. Cells harboring oncogene or tumor suppressor mutations are known to display heightened macropinocytosis, which confers to the cancer cells the a作者: Mumble 時(shí)間: 2025-3-26 20:23
The Amoebal Model for Macropinocytosisextended from the plasma membrane, then digest their contents and absorb the nutrients in the endo-lysosomal system. They use macropinocytosis for feeding, maintaining a high rate of fluid uptake that makes assay and experimentation easy. Mutants collected over the years identify cytoskeletal and si作者: Inoperable 時(shí)間: 2025-3-26 21:43 作者: Grievance 時(shí)間: 2025-3-27 01:08 作者: 不如樂(lè)死去 時(shí)間: 2025-3-27 08:10 作者: 葡萄糖 時(shí)間: 2025-3-27 09:57
Roles for 3’ Phosphoinositides in Macropinocytosis and transitions between those stages. Each stage in the process is regulated by variously phosphorylated derivatives of phosphatidylinositol (PtdIns) which reside in the cytoplasmic face of the membrane lipid bilayer. PtdIns derivatives phosphorylated at the 3’ position of the inositol moiety, call作者: esoteric 時(shí)間: 2025-3-27 13:41 作者: 離開(kāi)就切除 時(shí)間: 2025-3-27 19:29 作者: Ostrich 時(shí)間: 2025-3-28 01:25 作者: 結(jié)構(gòu) 時(shí)間: 2025-3-28 03:28
KRASG12R-Independent Macropinocytosis in Pancreatic Cancerch activates the PI3Kα lipid kinase and RAC1, to drive membrane ruffling, macropinosome uptake and processing. However, our recent study on the KRAS. mutant indicated the presence of a KRAS-independent mode of macropinocytosis in pancreatic cancer cell lines, thereby increasing the complexity of thi作者: Induction 時(shí)間: 2025-3-28 06:22
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