標(biāo)題: Titlebook: Macrolide Antibiotics; Wolfgang Sch?nfeld,Herbert A. Kirst Book 2002 Springer Basel AG 2002 Antibiotika.Infektionskrankheiten.Sexually Tra [打印本頁] 作者: 歸納 時間: 2025-3-21 19:20
書目名稱Macrolide Antibiotics影響因子(影響力)
作者: Monotonous 時間: 2025-3-21 22:28 作者: hauteur 時間: 2025-3-22 04:29 作者: 北極熊 時間: 2025-3-22 08:34
Cellular accumulation of macrolide antibiotics. Intracellular bioactivity,ch some molecules are mainly antibacterial (true macrolides) whereas others possess mainly immunosuppressant activity (FK 506, rapamycin) or antifungal activity with host cell inhibitory properties (bafilomycins, concannamycins). Traditional macrolide antibiotics are characterized by a 12- to 16-mem作者: Gleason-score 時間: 2025-3-22 10:33 作者: pulmonary-edema 時間: 2025-3-22 14:38 作者: dithiolethione 時間: 2025-3-22 20:10
Ketolides: novel antibacterial agents designed to overcome resistance to erythromycin A within gramnaseproducing resistant strains appeared in London hospitals very shortly after the early clinical use of penicillin G, and they soon spread worldwide [.]. Erythromycin use rapidly was limited by the development of other drugs active on penicillin G-resistant S. aureus isolates and by the fact that 作者: 壓倒 時間: 2025-3-23 00:52 作者: ineluctable 時間: 2025-3-23 02:10 作者: Monotonous 時間: 2025-3-23 09:17
Biosynthesis of the macrolide antibiotic, tylosin,rporation studies and bioconversion analysis, with heavy reliance on the use of mutants of . blocked in tylosin production [.-.]. The primary product of the Ty1G polyketide synthase is a 16-atom lactone (protylonolide, synonym tylactone) that subsequently acquires three deoxyhexose substituents (D-m作者: Lobotomy 時間: 2025-3-23 11:17
Activity of macrolides against mycobacteria, proportion of all serious infectious disorders observed worldwide. Estimates of the numbers of leprosy cases exceed 20 million. Tuberculosis in all of its forms is believed to be the most common of the fatal infections, with total annual mortality figures of three million adult deaths of adults in 作者: 鎮(zhèn)壓 時間: 2025-3-23 17:40
, and asthma and atherosclerosis: role of macrolides,tracellular parasites that have a unique developmental cycle with morphologically distinct infectious and reproductive forms. All members of the genus have a gram-negative envelope without peptidoglycan, share a genus-specific lipopolysaccharide (LPS) antigen, and utilize host ATP for the synthesis 作者: TATE 時間: 2025-3-23 21:52
Activity of macrolides in sexually transmitted diseases,led with the established safety profile of erythromycin and the advent of newer compounds with improved pharmacokinetic and pharmacodynamic profiles of particular relevance to bacterial sexually transmitted diseases (STDs), has resulted in a recent surge of interest in their clinical use.作者: 勤勞 時間: 2025-3-23 22:22 作者: 糾纏,纏繞 時間: 2025-3-24 06:26
Effects of macrolide antibiotics on ribosome function,n composition of this organelle, a disproportionately large number of structurally diverse agents target the ribosome. The ribosome catalyzes polymerization of amino acids in the sequence dictated by the nucleotide sequence in mRNA. The process of protein biosynthesis requires a spatial and temporal作者: 乏味 時間: 2025-3-24 10:21 作者: 瑪瑙 時間: 2025-3-24 12:11 作者: 態(tài)度暖昧 時間: 2025-3-24 16:56 作者: anaerobic 時間: 2025-3-24 20:12 作者: 重畫只能放棄 時間: 2025-3-24 23:19 作者: bronchodilator 時間: 2025-3-25 07:20
Marie-Thérèse Labro. This chapter gives a brief summary of the history of LCA since then with a focus on the fields of methodological development, application, international harmonisation and standardisation, and dissemination. LCA had its early roots in packaging studies and focused mainly on energy use and a few emi作者: Seminar 時間: 2025-3-25 10:35
Takashi Adachi,Shigeo Morimotoelementary flows is translated into environmental impact scores. In contrast to the three other LCA phases, LCIA is in practice largely automated by LCA software, but the underlying principles, models and factors should still be well understood by practitioners to ensure the insight that is needed f作者: 過渡時期 時間: 2025-3-25 12:10
Wolfgang Sch?nfeld,Stjepan Mutakfull life cycle sustainability assessment, but often system delimitations differ depending on the goal and scope of the study. To provide a profound understanding this chapter describes several approaches and terms, fundamental principles and different types of costs. A brief introduction is given t作者: 邊緣帶來墨水 時間: 2025-3-25 19:01
André Bryskier,Alexis Denisity, such as resource scarcity and waste reduction. Improvements in sustainable resource consumption practices like material efficiency, reuse, repairs, design for long life, recycling efficiency, etc. are promising CE strategies to improve the resource use efficiency of rare earth elements (REEs). 作者: extemporaneous 時間: 2025-3-25 20:34 作者: Water-Brash 時間: 2025-3-26 01:45 作者: foreign 時間: 2025-3-26 06:50
Eric Cundliffedifferentiates this tool from existing alternatives which largely fail to capitalise upon the concept of life cycle thinking and whose potential to integrate the holistic vision into assessment of environmental impacts from tourism products and services is therefore limited. There are however a numb作者: Irksome 時間: 2025-3-26 08:58 作者: photophobia 時間: 2025-3-26 12:56 作者: Hirsutism 時間: 2025-3-26 20:39
Margaret R. Hammerschlagdeal intensively with questions of environmental management. Swiss scientists claim to be among the first to have developed concepts of LCA, ecological accounting and environmental management of firms and nations (i.e. Müller-Wenk 1974 and 1978; Braunschweig 1987; Schaltegger and Sturm 1990 and 1992作者: indigenous 時間: 2025-3-26 23:54
Geoffrey L. Ridgwaydeal intensively with questions of environmental management. Swiss scientists claim to be among the first to have developed concepts of LCA, ecological accounting and environmental management of firms and nations (i.e. Müller-Wenk 1974 and 1978; Braunschweig 1987; Schaltegger and Sturm 1990 and 1992作者: 干涉 時間: 2025-3-27 02:08 作者: dialect 時間: 2025-3-27 09:20 作者: START 時間: 2025-3-27 11:40
Joyce A Sutcliffe,Roland Leclercqa, determining the impact on nature and communicating the non-confidential part of these data to the public. Environmental management is a very powerful approach for a company to evaluate the relevant impact on the environment and to find the most efficient way possible to reduce this impact. Publis作者: biopsy 時間: 2025-3-27 15:24
a, determining the impact on nature and communicating the non-confidential part of these data to the public. Environmental management is a very powerful approach for a company to evaluate the relevant impact on the environment and to find the most efficient way possible to reduce this impact. Publis作者: Vertebra 時間: 2025-3-27 18:05
ciation and the context of description of the largely public “high art” that essentially defines these traditions, and that when this public or institutional tradition is supplemented by examples of more “private art,” that usually involves examples of elite or (as in the Renaissance and 17th centur作者: instructive 時間: 2025-3-27 22:49 作者: 勤勉 時間: 2025-3-28 03:30
Vito R. Iacoviello,Stephen H. Zinner includes a chapter entitled “The History of a Self Tormentor,” a chapter title that is extradiagetic, imposed by the author on a first-person narration by a Miss Wade. Dickens’ chapter shows similarities to the descriptions given in Fowles’ . by the novel’s narrator and by its main female character作者: 擴(kuò)音器 時間: 2025-3-28 09:22
Holly M. Mattoes,Charles H. Nightingales provided as well as guidance on how to collect data to overcome this hurdle. In an illustrative case study on window frames, the eLCC theory is applied and demonstrated with each step along the eLCC procedure described in detail. A final section about advanced LCC introduces how to monetarise exte作者: WAX 時間: 2025-3-28 11:15 作者: Obituary 時間: 2025-3-28 16:04
Takashi Adachi,Shigeo Morimoto reader is taken through (a) the underlying environmental problem, (b) the underlying environmental mechanism and its fundamental modelling principles, (c) the main anthropogenic sources causing the problem and (d) the main methods available in LCIA. An annex to this book offers a comprehensive qual作者: 埋葬 時間: 2025-3-28 20:19 作者: BUCK 時間: 2025-3-29 02:10 作者: fatty-streak 時間: 2025-3-29 05:16 作者: 鉗子 時間: 2025-3-29 08:29 作者: 建筑師 時間: 2025-3-29 14:34 作者: 贊美者 時間: 2025-3-29 17:37 作者: 極少 時間: 2025-3-29 19:54 作者: calumniate 時間: 2025-3-30 02:02 作者: 溝通 時間: 2025-3-30 05:39
Geoffrey L. Ridgwayded to establish the coordinated project LCA and eco-controlling (KOP?) in the Priority Programme Environment. The main purpose was to analyze the strengths and weaknesses of the LCA of products, to develop methods for environmental management, and to promote their application in practice. The prese作者: nullify 時間: 2025-3-30 09:46 作者: beta-cells 時間: 2025-3-30 12:45
Norris E. Allended to establish the coordinated project LCA and eco-controlling (KOP?) in the Priority Programme Environment. The main purpose was to analyze the strengths and weaknesses of the LCA of products, to develop methods for environmental management, and to promote their application in practice. The prese作者: 熱情的我 時間: 2025-3-30 17:37 作者: 過份好問 時間: 2025-3-30 23:51 作者: subacute 時間: 2025-3-31 04:53 作者: 邊緣 時間: 2025-3-31 08:34
Pharmacokinetics/pharmacodynamics of macrolides,teractions make it a difficult drug to use clinically [., ., .]. As a result, newer macrolides have been developed, and the newer macrolide/azalide drugs, azithromycin and clarithromycin, will be the focus of this chapter. Data on roxithromycin as well as the macrolides josamycin and spiramycin, whi作者: FAST 時間: 2025-3-31 11:39
Cellular accumulation of macrolide antibiotics. Intracellular bioactivity,ubstituents, or introducing a nitrogen atom into the lactone (azalides), or, more recently, by withdrawing the L-cladinose at position 3 of the lactone ring and replacing it by a 3-keto function (ketolides). All these compounds display a substantially homogeneous antimicrobial spectrum and the capab作者: Hallowed 時間: 2025-3-31 14:26
Biosynthesis of the macrolide antibiotic, tylosin,DNA fragments [., .] allowed the mapping of 13 . loci within the . genome, alongside other attempts to identify the tylosin-production genes. Success in this regard eventually resulted from two convergent approaches instigated at Lilly Research Laboratories, Indianapolis.作者: 是限制 時間: 2025-3-31 21:03
, and asthma and atherosclerosis: role of macrolides,ssue and cells, including polymorphonuclear leukocytes and macrophages. These drugs also have long half-lives in tissue, allowing once-daily dosing and shorter duration of therapy. However, data on the treatment of even respiratory infection due to . is limited. Although currently available macrolid作者: Isometric 時間: 2025-4-1 01:37
Effects of macrolide antibiotics on ribosome function,n, and clindamycin among others) interfere with the relatively weak interactions between the 3’-CCA-aminoacyl terminus of tRNA and the peptidyltransferase center. Agents that disrupt the much stronger codon-dependent interactions include streptomycin and other aminoglycoside antibiotics.
