作者: Climate 時(shí)間: 2025-3-21 22:42
y. The book is for researchers whose specialty is RNA biology and chemistry and also for advanced students at the graduate and undergraduate levels. Readers can grasp the leading edge of lncRNA studies in a com978-4-431-56262-7978-4-431-55576-6作者: Meander 時(shí)間: 2025-3-22 00:57
rgehoben und ist seitdem von allen Beobachtern best?tigt worden. Besondere Untersuchungen über sie haben .., .., . und .. sowie .. ausgeführt; den Extremfall eines solchen gest?rten Spektrums beobachtete .. bei Funkenentladungen in Wasserstoff von hohem Druck.作者: 連接 時(shí)間: 2025-3-22 06:44
Aleks Schein,Piero Carnincirgehoben und ist seitdem von allen Beobachtern best?tigt worden. Besondere Untersuchungen über sie haben .., .., . und .. sowie .. ausgeführt; den Extremfall eines solchen gest?rten Spektrums beobachtete .. bei Funkenentladungen in Wasserstoff von hohem Druck.作者: 真實(shí)的你 時(shí)間: 2025-3-22 10:26 作者: Sputum 時(shí)間: 2025-3-22 14:46 作者: Terminal 時(shí)間: 2025-3-22 18:55 作者: Increment 時(shí)間: 2025-3-23 00:11
Karmel A. Allison,Christopher K. Glassen. In der Konsequenz dieser Entwicklung entsteht eine zunehmende Notwendigkeit, dass Unternehmen mit der steigenden Komplexit?t und Dynamik umgehen k?nnen müssen, um auch bei diesen, sich ver?ndernden Bedingungen wettbewerbsf?hig zu bleiben. Das Eingehen von Kooperationen wird in der wirtschaftswis作者: absorbed 時(shí)間: 2025-3-23 02:37 作者: 厭惡 時(shí)間: 2025-3-23 08:22
ke. Daher ist meist eine selektive Beschr?nkung auf gegenw?rtig diskutierte Positionen n?tig, wobei sich aber gelegentlich aus systematischen Gründen auch ein Rückgriff auf Konzeptionen als sinnvoll erweist, die an Aktualit?t verloren haben. Diese überlegungen verstehen sich somit als Beitrag zur . 作者: palette 時(shí)間: 2025-3-23 13:25
Complexity of Mammalian Transcriptome Analyzed by RNA Deep Sequencing genome was considered silent and non-functional, until on-going research revealed that about 80 % of DNA might be transcribed, producing numerous long noncoding RNA molecules with important functions. This chapter gives an overview of mammalian transcriptome research in recent decades. It discusses作者: 空中 時(shí)間: 2025-3-23 16:04
Synthetic Strategies to Identify and Regulate Noncoding RNAsble researchers to develop novel therapeutic strategies and would aid the elucidation of the intricate translational machinery. In this chapter, we give a chemical perspective of ncRNAs and detail the synthetic strategies available to modulate novel RNA structures, which have been identified as ther作者: neutrophils 時(shí)間: 2025-3-23 21:20
Structure and Interaction with Protein of Noncoding RNA: A Case for an RNA Aptamer Against Prion Proased assay demonstrated that R12 reduces the amount of the abnormal form of prion protein and thus exerts anti-prion activity. The R12 aptamer may be utilized to develop drugs against prion diseases and Alzheimer’s disease.作者: nascent 時(shí)間: 2025-3-23 23:52
Characterization of G-Quadruplex DNA- and RNA-Binding Proteinitution of Tyr for Phe in the RGG motif of TLS converts its binding specificity solely toward G-quadruplex TERRA. This molecule binds to loops within the G-quadruplexes of TERRA by recognizing the 2′-OH of the riboses. It will be useful for investigating biological roles of the G-quadruplex in long 作者: HEPA-filter 時(shí)間: 2025-3-24 05:04 作者: 爵士樂(lè) 時(shí)間: 2025-3-24 08:55
Long Noncoding RNAs as Structural and Functional Components of Nuclear Bodiesanscriptional and post-transcriptional regulation of genes by modulating the function and localization of related regulatory proteins. In this review, we focus on the recently unveiled roles of lncRNAs that act as structural and/or functional components of nuclear bodies.作者: Stable-Angina 時(shí)間: 2025-3-24 12:24 作者: V切開(kāi) 時(shí)間: 2025-3-24 18:10
Mechanisms of Long Noncoding Xist RNA-Mediated Chromosome-Wide Gene Silencing in X-Chromosome InactiXist RNA-mediated chromosome-wide silencing and particularly the Xist RNA domains and protein factors essential for Xist RNA localization on the Xi. In this chapter, we describe recent novel findings in X-inactivation with a special focus on how Xist RNA localizes on the Xi . and recruits various ch作者: erythema 時(shí)間: 2025-3-24 20:24 作者: Dealing 時(shí)間: 2025-3-24 23:57 作者: Exuberance 時(shí)間: 2025-3-25 05:25 作者: 挫敗 時(shí)間: 2025-3-25 10:45
Long Noncoding RNA Functions as a Regulator for Steroid Hormone Receptor-Related Breast and Prostatethe context of the NR functional network, focusing on the molecular mechanism, biological significance, and clinical relevance of these lncRNA regulators. Several breast/prostate cancer-associated lncRNA regulators not yet directly linked to NRs are also included in this chapter.作者: GLUT 時(shí)間: 2025-3-25 14:58
l points of view.Elaborates on molecular dissections of longThis book presents a common principle of actions of long noncoding RNAs (lncRNAs) from points of view at the atomic, molecular and cellular levels. At the atomic level, chemical studies of ribonucleic acids explain the chemical behavior of 作者: 值得 時(shí)間: 2025-3-25 17:10 作者: maudtin 時(shí)間: 2025-3-25 21:02 作者: ANA 時(shí)間: 2025-3-26 01:18 作者: 通知 時(shí)間: 2025-3-26 06:07
Synthetic Strategies to Identify and Regulate Noncoding RNAschinery within the cell. Recently, large-scale sequencing techniques to analyze mammalian transcriptomes have substantiated the importance of the diverse population of the unannotated regions of the genome called noncoding RNAs (ncRNAs) in numerous biological processes and diseases. The ncRNAs demon作者: Nausea 時(shí)間: 2025-3-26 11:44 作者: calorie 時(shí)間: 2025-3-26 13:08
Characterization of G-Quadruplex DNA- and RNA-Binding Proteinats, which is a long noncoding RNA transcribed from the telomeres. Telomere DNA and TERRA form a G-quadruplex in vitro. The functions of the G-quadruplex structures in the telomere, however, are not clear, because little is known about G-quadruplex specific binding proteins and G-quadruplex RNA-bind作者: Debark 時(shí)間: 2025-3-26 18:30
Initiation of Transcription Generates Divergence of Long Noncoding RNAsformation on amino acid sequences and consists of coding regions. Most noncoding regions produce long noncoding RNAs (lncRNAs), and some of them have been found to play biological roles in living cells. These sequences bearing lncRNAs display extensive diversity because of their origins from interge作者: 鞠躬 時(shí)間: 2025-3-27 00:53 作者: 不規(guī)則的跳動(dòng) 時(shí)間: 2025-3-27 04:50
Long Noncoding RNAs as Structural and Functional Components of Nuclear Bodiess. Nuclear bodies are thought to serve as sites for the biogenesis, assembly, and storage of specific proteins and RNAs. In the last decade, multiple nuclear bodies were found to contain long noncoding RNAs (lncRNAs), and the physiological and molecular functions of these lncRNAs have been elucidate作者: LANCE 時(shí)間: 2025-3-27 06:40 作者: 出汗 時(shí)間: 2025-3-27 11:23
Mechanisms of Long Noncoding Xist RNA-Mediated Chromosome-Wide Gene Silencing in X-Chromosome Inacting enzymes are recruited to their specific target loci remains largely unknown. Recent findings using deep sequencing analysis revealed that various chromatin-modifying enzymes interact with a variety of long noncoding RNAs (lncRNAs), suggesting the potential role of lncRNA in targeting chromatin-mo作者: antiandrogen 時(shí)間: 2025-3-27 14:22
Regulation of pRB and p53 Pathways by the Long Noncoding RNAs ,, ,, ,, and ,age. Disruption of these pathways deregulates the control of cell proliferation and represents a common event in the development of most types of human cancer. Recent studies have revealed that several long noncoding RNAs (lncRNAs) are involved in the regulation of pRB and p53 pathways, through tran作者: exorbitant 時(shí)間: 2025-3-27 21:45
The Role of Androgen-Regulated Long Noncoding RNAs in Prostate Cancerwith cancer. Systematic analysis of transcription factor-binding sites and the regulated transcripts revealed that many lncRNAs are widely regulated at the transcriptional level. However, the functions of these transcripts have not been fully elucidated. In this study, using prostate cancer cells, w作者: theta-waves 時(shí)間: 2025-3-28 00:38 作者: animated 時(shí)間: 2025-3-28 02:34
Long Noncoding RNA Functions as a Regulator for Steroid Hormone Receptor-Related Breast and Prostated prostate cancer. The precise and dynamic regulation of steroid hormone receptors, members of the nuclear receptor (NR) gene family, remains an essential, evolving question. Here we summarize several recent studies that have uncovered the roles of a new layer of NR regulators, long noncoding RNAs (作者: 步兵 時(shí)間: 2025-3-28 07:51
h. isoliert im Raum ohne Beeinflussung durch Felder und ohne Wechselwirkung mit Nachbarteilchen betrachtet. Dieser Annahme entsprachen Spektren, die bis zur Seriengrenze einzelne scharfe Linien aufwiesen, an die sich genau von der Grenze an nach kurzen Wellen zu ein kontinuierliches Spektrum anschlo作者: TAIN 時(shí)間: 2025-3-28 13:19
Aleks Schein,Piero Carnincih. isoliert im Raum ohne Beeinflussung durch Felder und ohne Wechselwirkung mit Nachbarteilchen betrachtet. Dieser Annahme entsprachen Spektren, die bis zur Seriengrenze einzelne scharfe Linien aufwiesen, an die sich genau von der Grenze an nach kurzen Wellen zu ein kontinuierliches Spektrum anschlo作者: 合群 時(shí)間: 2025-3-28 18:01 作者: intellect 時(shí)間: 2025-3-28 22:47
Riki Kurokawakreten Zeitpunkten vorgenommen wurde und meist fundamentalen Charakter hatte — Ausnahme sind einige Studien in der Populations?kologie, in denen auch periphere ?nderungen behandelt werden — konzentriert. Dies darf aber nicht zu der Ansicht führen, dass es überhaupt keine Untersuchungen über inkremen作者: STALE 時(shí)間: 2025-3-29 02:01 作者: 阻擋 時(shí)間: 2025-3-29 06:23 作者: Exclaim 時(shí)間: 2025-3-29 09:01
Karmel A. Allison,Christopher K. Glasswie ?Hyper-Linking“, ?Hyper-Competition“ und ?Hyper-Turbulence“ umschreiben, die in direktem Zusammenhang mit Effekten stehen, die mit der vielbesprochenen Globalisierung einhergehen. Hyper-Linking beschreibt dabei die zunehmende Anzahl von miteinander in Verbindung stehenden Akteuren im Umfeld von 作者: 儀式 時(shí)間: 2025-3-29 15:15 作者: fledged 時(shí)間: 2025-3-29 18:25
den von Elisabeth Walther von 1981. An ihn knüpfen die folgen überlegungen an. Max Benses Interessen bei der Anwendung dieser aus dem Ansatz von Ch. S. Peirce entwickelten Semiotikkonzeption lagen bekanntlich eher auf den Bereichen von Kunst und Wissenschaft. Die zeitgen?ssische Ethik wiederum inter作者: 不連貫 時(shí)間: 2025-3-29 23:07
https://doi.org/10.1007/978-4-431-55576-6Bioinformatics; Chemical biology; Epigenetics; Macrophage; RNA medicine; Steroid hormone; Transcription; X-作者: 胰島素 時(shí)間: 2025-3-29 23:57 作者: 光滑 時(shí)間: 2025-3-30 04:22 作者: 類型 時(shí)間: 2025-3-30 09:50
Beneath the Veil of Biological Complexity There Lies Long Noncoding RNA: Diverse Utilization of lncRanscribed. Although yeasts have relatively small portion of noncoding genome, they produces some functional ncRNAs. In this chapter, we overview recent studies on the function of yeast long ncRNAs in epigenetic regulation, cell-cycle control, centromere/telomere functions, and responses to environmental stimuli.作者: Accrue 時(shí)間: 2025-3-30 16:05
9樓作者: Monocle 時(shí)間: 2025-3-30 19:18
10樓作者: 使迷惑 時(shí)間: 2025-3-30 20:58
10樓作者: RUPT 時(shí)間: 2025-3-31 00:55
10樓作者: appall 時(shí)間: 2025-3-31 08:24
10樓
