標(biāo)題: Titlebook: Lipids in Protein Misfolding; Olga Gursky Book 2015 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer N [打印本頁] 作者: Iridescent 時間: 2025-3-21 19:47
書目名稱Lipids in Protein Misfolding影響因子(影響力)
書目名稱Lipids in Protein Misfolding影響因子(影響力)學(xué)科排名
書目名稱Lipids in Protein Misfolding網(wǎng)絡(luò)公開度
書目名稱Lipids in Protein Misfolding網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Lipids in Protein Misfolding被引頻次
書目名稱Lipids in Protein Misfolding被引頻次學(xué)科排名
書目名稱Lipids in Protein Misfolding年度引用
書目名稱Lipids in Protein Misfolding年度引用學(xué)科排名
書目名稱Lipids in Protein Misfolding讀者反饋
書目名稱Lipids in Protein Misfolding讀者反饋學(xué)科排名
作者: 狼群 時間: 2025-3-21 23:07
0065-2598 influence protein misfolding and amyloid diseases.Provides a?Protein conversion from a water-soluble native conformation to the insoluble aggregates and fibrils, which can deposit in amyloid plaques, underlies more than 20 human diseases, representing a major public health problem and a scientific c作者: EXPEL 時間: 2025-3-22 03:11 作者: jarring 時間: 2025-3-22 07:30
Olga GurskyExplains how protein misfolding is an important biological phenomenon underlying over 20 major human diseases.Shows that Lipids importantly influence protein misfolding and amyloid diseases.Provides a作者: RLS898 時間: 2025-3-22 09:56 作者: integral 時間: 2025-3-22 16:35
https://doi.org/10.1007/978-3-319-17344-3amyloid formation; biophysical and structural approaches; molecular mechanisms of protein misfolding; p作者: Aggressive 時間: 2025-3-22 18:56 作者: exacerbate 時間: 2025-3-23 01:03
Lipids in Protein Misfolding978-3-319-17344-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 狼群 時間: 2025-3-23 05:08 作者: 引起 時間: 2025-3-23 06:09
Protein Misfolding in Lipid-Mimetic Environments,elations between the aggregating proteins and cell membranes. On one hand, the unstable, toxic pre-fibrillar aggregates may interact with cell membranes, impairing their functions, altering ion distribution across the membranes, and possibly forming non-specific membrane pores. On the other hand, me作者: dissolution 時間: 2025-3-23 13:31
,Lipids in Amyloid-β Processing, Aggregation, and Toxicity,sis play important roles in this and other neurodegenerative disorders. The complex interplay between the lipids and the generation, clearance or deposition of Aβ has been intensively investigated and is reviewed in this chapter. Membrane lipids can have an important influence on the biogenesis of A作者: NOVA 時間: 2025-3-23 14:37
Role of Cholesterol and Phospholipids in Amylin Misfolding, Aggregation and Etiology of Islet Amyloes that are often toxic to cells. Exactly how amyloid proteins, such as the pancreatic hormone amylin, aggregate and kill cells is still unclear. Islet amyloid polypeptide, or amylin, is a recently discovered hormone that is stored and co-released with insulin from pancreatic islet β-cells. The path作者: CHAFE 時間: 2025-3-23 21:43
Intrinsic Stability, Oligomerization, and Amyloidogenicity of HDL-Free Serum Amyloid A,cal and pathological roles. Upon tissue trauma or infection, hepatic expression of SAA increases up to 1,000 times the basal levels. Prolonged increased levels of SAA may lead to amyloid A (AA) amyloidosis, a usually fatal systemic disease in which the amyloid deposits are mostly comprised of the N-作者: 噴出 時間: 2025-3-24 01:25 作者: 闡釋 時間: 2025-3-24 05:41
The Role of Lipid in Misfolding and Amyloid Fibril Formation by Apolipoprotein C-II,When bound to lipoprotein particles, these proteins are relatively stable. However, in the absence of lipids they display conformational instability and a propensity to aggregate into amyloid fibrils. Apolipoprotein C-II (apoC-II) is a member of the apolipoprotein family that has been well character作者: 哥哥噴涌而出 時間: 2025-3-24 10:01
Amyloid-Forming Properties of Human Apolipoproteins: Sequence Analyses and Structural Insights,d disease. Soluble apolipoproteins can transiently dissociate from the lipoprotein surface in a labile free form that can misfold, potentially leading to amyloid disease. Misfolding of apoA-I, apoA-II, and serum amyloid A (SAA) causes systemic amyloidoses, apoE4 is a critical risk factor in Alzheime作者: noxious 時間: 2025-3-24 12:15 作者: 前兆 時間: 2025-3-24 17:21 作者: TRACE 時間: 2025-3-24 19:07 作者: manifestation 時間: 2025-3-25 00:30
Heedeok Hongies the author primarily uses angle-resolved X-ray photoelectron spectroscopy under ultrahigh vacuum conditions. ILs represent a class of materials with unique physico-chemical properties. Many applications take advantage of the extremely low vapor pressure of aprotic ILs to fabricate permanent, non作者: 擺動 時間: 2025-3-25 05:11
Sanghamitra Singh,Saurabh Trikha,Diti Chatterjee Bhowmick,Anjali A. Sarkar,Aleksandar M. Jeremic systems” are just three of quotes from the reports of referees for research proposals that I have received over the years. I wonder what these people think today. There are currently at least nine large-scale industrial uses of ionic liquids, including, we now rec- nise, the production of ?-Caprola作者: 嬉耍 時間: 2025-3-25 10:53
Wilfredo Colón,J. Javier Aguilera,Saipraveen Srinivasan systems” are just three of quotes from the reports of referees for research proposals that I have received over the years. I wonder what these people think today. There are currently at least nine large-scale industrial uses of ionic liquids, including, we now rec- nise, the production of ?-Caprola作者: deficiency 時間: 2025-3-25 12:15
Galyna Gorbenko,Valeriya Trusova,Mykhailo Girych,Emi Adachi,Chiharu Mizuguchi,Hiroyuki Saito systems” are just three of quotes from the reports of referees for research proposals that I have received over the years. I wonder what these people think today. There are currently at least nine large-scale industrial uses of ionic liquids, including, we now rec- nise, the production of ?-Caprola作者: 創(chuàng)造性 時間: 2025-3-25 19:29
Timothy M. Ryan,Yee-Foong Mok,Geoffrey J. Howlett,Michael D. W. Griffinmistry, each written by the world renowned experts.Still val“Ionic liquids will never find application in industry”, “I don’t understand this fad for ionic liquids” and “there is no widespread interest in these systems” are just three of quotes from the reports of referees for research proposals tha作者: 占卜者 時間: 2025-3-25 23:00
Madhurima Das,Olga Gurskymistry, each written by the world renowned experts.Still val“Ionic liquids will never find application in industry”, “I don’t understand this fad for ionic liquids” and “there is no widespread interest in these systems” are just three of quotes from the reports of referees for research proposals tha作者: mendacity 時間: 2025-3-26 00:17 作者: synchronous 時間: 2025-3-26 07:02
Elena I. Leonova,Oxana V. Galzitskayamistry, each written by the world renowned experts.Still val“Ionic liquids will never find application in industry”, “I don’t understand this fad for ionic liquids” and “there is no widespread interest in these systems” are just three of quotes from the reports of referees for research proposals tha作者: Affectation 時間: 2025-3-26 11:11 作者: 感情脆弱 時間: 2025-3-26 16:15 作者: FATAL 時間: 2025-3-26 19:57 作者: Affirm 時間: 2025-3-26 23:22 作者: Incisor 時間: 2025-3-27 04:38 作者: incontinence 時間: 2025-3-27 07:49 作者: Ligneous 時間: 2025-3-27 11:48
Role of Lipids in Folding, Misfolding and Function of Integral Membrane Proteins, similarity. Furthermore, the atomic structures of the same protein in different lipid environments are also very similar. This suggests that certain stable folds optimized for a specific function have been selected by evolution. On the other hand, there is growing evidence that, despite the overall作者: Left-Atrium 時間: 2025-3-27 15:37 作者: Intrepid 時間: 2025-3-27 21:24
,Lipids in Amyloid-β Processing, Aggregation, and Toxicity,actor for AD. Aβ is an amphiphilic peptide that interacts with various lipids, proteins and their assemblies, which can lead to variation in Aβ aggregation in vitro and in vivo. Upon interaction with the lipid raft components, such as cholesterol, gangliosides and phospholipids, Aβ can aggregate on 作者: hurricane 時間: 2025-3-27 22:31 作者: GIBE 時間: 2025-3-28 02:27
Intrinsic Stability, Oligomerization, and Amyloidogenicity of HDL-Free Serum Amyloid A,ibrils in vitro at 37 °C whereas pathogenic mSAA1.1 has a long lag (nucleation) phase, and eventually forms fibrils of different morphology than mSAA2.2. Remarkably, human SAA1.1 does not form mature fibrils in vitro. Thus, it appears that the intrinsic amyloidogenicity of SAA is not a key determina作者: Capture 時間: 2025-3-28 08:47
Interactions of Lipid Membranes with Fibrillar Protein Aggregates,and analyze fluorescence data reporting on lipid bilayer interactions with fibrillar lysozyme and with the N-terminal 83-residue fragment of amyloidogenic mutant apolipoprotein A-I, 1-83/G26R/W@8. The results help understand possible mechanisms of interaction and mutual remodeling of amyloid fibers 作者: DEMN 時間: 2025-3-28 13:42 作者: amphibian 時間: 2025-3-28 16:53
Amyloid-Forming Properties of Human Apolipoproteins: Sequence Analyses and Structural Insights,ts that are likely to initiate β-aggregation. Mapping such segments on the available atomic structures of apolipoproteins helps explain why some of them readily form amyloid while others do not. Our analysis shows that nearly all amyloidogenic segments: (i) are largely hydrophobic, (ii) are located 作者: 突變 時間: 2025-3-28 20:08
Computational Approaches to Identification of Aggregation Sites and the Mechanism of Amyloid Growth-servers that combine several independent approaches, and by the method PASTA2. Thus, correct prediction of amyloidogenic segments remains a difficult task. Additional data and new algorithms that are becoming available are expected to improve the accuracy of the prediction methods, particularly if 作者: insurgent 時間: 2025-3-28 23:48
Role of Syndecans in Lipid Metabolism and Human Diseases,ptor with its agonist, leading to an increased appetite. Finally, syndecan-4 initiates the capture of modified low-density lipoproteins by macrophages and thereby promotes the atheroma formation. We hypothesize that syndecan modifications such as desulfation of glycosaminoglycan chains may contribut作者: 搖曳的微光 時間: 2025-3-29 05:17 作者: 男學(xué)院 時間: 2025-3-29 07:51
supported ionic liquid catalysis. His results have significantly contributed to the present level of understanding in the field and accordingly he is author and coauthor of ten publications on the topic in hig978-3-319-03345-7978-3-319-00380-1Series ISSN 2190-5053 Series E-ISSN 2190-5061 作者: reflection 時間: 2025-3-29 14:28
