作者: Coterminous 時間: 2025-3-21 22:22
Joachim Rüdiger D?hler FRCSeddifferentiation. The multiple functions of the IFN system are thought to be an innate defense against microbes and foreign substances. The IFN system consists first of cells that produce IFNs in response to viral infection or other foreign stimuli and second of cells that establish the antiviral sta作者: 過多 時間: 2025-3-22 00:44
Joachim Rüdiger D?hler FRCSednd structurally heterogeneous. For example, the existence of multiple gene products of the IFN a family suggests that there may be specific roles for different molecular subtypes during stages of differentiation and development (Nagata et al., 1980). The capacity of interferon to exhibit such divers作者: 詞匯表 時間: 2025-3-22 05:24
Joachim Rüdiger D?hler FRCSedhe possibility that they could play a non-antiviral role came first from studies in which it was demonstrated that interferon could enhance the killing of tumor cells by normal lymphocytes both . and .. Initially such studies were carried out with virus induced tumors, where it was shown that interf作者: bifurcate 時間: 2025-3-22 09:03
Joachim Rüdiger D?hler FRCSedo a major force in the antiviral response. Initially studied only by few virologists, IFN was generally considered as a poorly defined protein of limited importance. The development of molecular techniques lead to the identification of a family of IFN genes and has shown an unexpected complexity of 作者: coagulation 時間: 2025-3-22 16:21
Joachim Rüdiger D?hler FRCSedo a major force in the antiviral response. Initially studied only by few virologists, IFN was generally considered as a poorly defined protein of limited importance. The development of molecular techniques lead to the identification of a family of IFN genes and has shown an unexpected complexity of 作者: Exclude 時間: 2025-3-22 18:02
Joachim Rüdiger D?hler FRCSedo a major force in the antiviral response. Initially studied only by few virologists, IFN was generally considered as a poorly defined protein of limited importance. The development of molecular techniques lead to the identification of a family of IFN genes and has shown an unexpected complexity of 作者: neurologist 時間: 2025-3-23 01:06 作者: Cerebrovascular 時間: 2025-3-23 05:06
Joachim Rüdiger D?hler FRCSeded from an inhibitor of viral replication to a major force in the antiviral response. Initially studied only by few virologists, IFN was generally considered as a poorly defined protein of limited importance. The development of molecular techniques lead to the identification of a family of IFN genes作者: 后天習得 時間: 2025-3-23 08:02 作者: 單調(diào)女 時間: 2025-3-23 12:54
Joachim Rüdiger D?hler FRCSedions. The antitumor properties of other compounds have been revealed through systematic screening programs, such as the natural substances screening program of the National Cancer Institute. The history of these therapies is relatively short, and it includes original clinical or biological observati作者: SENT 時間: 2025-3-23 15:53 作者: 平項山 時間: 2025-3-23 18:03
Joachim Rüdiger D?hler FRCSeden [1–5]. Seit kurzem wird IFN-α bei der Haarzellen-Leuk?mie und chronischen myeloischen Leuk?mie in der Klinik erfolgreich eingesetzt [6–8], jedoch ist der jeweilige Wirkmechanismus weitgehend ungekl?rt. Aus zahlreichen in-vitro-Studien ist bekannt, da? Interferone ausschlie?lich über Bindung an sp作者: craving 時間: 2025-3-24 01:09 作者: 失望未來 時間: 2025-3-24 04:49
Joachim Rüdiger D?hler FRCSedly fulfilled for the non-Hodgkin’s lymphomas (NHL). Classification of these malignancies is particularly difficult at present as molecular biologists, cytogeneticists, immunologists, histopathologists and clinicians all strive to increase diagnostic precision with the NHLs. This article concentrates作者: anthropologist 時間: 2025-3-24 09:50 作者: kyphoplasty 時間: 2025-3-24 10:47
Joachim Rüdiger D?hler FRCSed and chronic myelogenous leukemia interferon treatment has been able to produce not only improvements in peripheral blood counts and long lasting hematologic remissions, but reductions of the putative malignant clones found in the bone marrow. This chapter will review the clinical results of interfe作者: Muffle 時間: 2025-3-24 18:10
K. Mahlfeld and chronic myelogenous leukemia interferon treatment has been able to produce not only improvements in peripheral blood counts and long lasting hematologic remissions, but reductions of the putative malignant clones found in the bone marrow. This chapter will review the clinical results of interfe作者: Hiatus 時間: 2025-3-24 22:12
I. Pfefferkorn,P. Hinz,A. Ekkernkamps for global operations. In particular, much debate has been offered on management practices that are applicable to trigger desired customer behavior, especially, to enhance firm-level outcomes in terms of customer loyalty and word-of-mouth referral. However, research on mechanisms that can help dri作者: fatty-streak 時間: 2025-3-25 01:09
https://doi.org/10.1007/978-3-642-55838-2Bewegungsapparat; Chirurgie; Orthop?die; Unfallchirurgie; orthop?dische Chirurgie; Trauma Surgery作者: 蛛絲 時間: 2025-3-25 07:22 作者: ELUDE 時間: 2025-3-25 08:58
http://image.papertrans.cn/l/image/585458.jpg作者: 單純 時間: 2025-3-25 15:32 作者: GLUE 時間: 2025-3-25 19:46 作者: paragon 時間: 2025-3-25 22:22
on tumor cell proliferation, effector leukocytes and on apoptosis and have been used in the treatment of some cancers. Improved knowledge of how IFNs affect tumors and the mechanisms that lead to a lack of response to IFNs would help the development of better IFN treatments for malignancies.作者: 小隔間 時間: 2025-3-26 02:18 作者: 有斑點 時間: 2025-3-26 05:11
Joachim Rüdiger D?hler FRCSedferons elicit in cells are not selectively antiviral but sufficiently diverse to affect both viral and cellular metabolism. Nevertheless, the recent major advances in understanding the mechanism of action of interferon have come mainly from studies on the inhibition of viral replication.作者: 某人 時間: 2025-3-26 11:20 作者: 慷慨不好 時間: 2025-3-26 14:36
Joachim Rüdiger D?hler FRCSedgnition entity, leading to the expression of interferon and interferon induced genes, have been made in the recent year, which are challenging the accepted concept of the critical role of dsRNA in IFN induction. The availability of genetically modified mice that are lacking either essential componen作者: 斜 時間: 2025-3-26 20:37
Joachim Rüdiger D?hler FRCSedgnition entity, leading to the expression of interferon and interferon induced genes, have been made in the recent year, which are challenging the accepted concept of the critical role of dsRNA in IFN induction. The availability of genetically modified mice that are lacking either essential componen作者: CHYME 時間: 2025-3-26 21:11 作者: Enliven 時間: 2025-3-27 04:37
Joachim Rüdiger D?hler FRCSedgnition entity, leading to the expression of interferon and interferon induced genes, have been made in the recent year, which are challenging the accepted concept of the critical role of dsRNA in IFN induction. The availability of genetically modified mice that are lacking either essential componen作者: Immunotherapy 時間: 2025-3-27 08:11 作者: painkillers 時間: 2025-3-27 13:18 作者: Metastasis 時間: 2025-3-27 15:34 作者: Electrolysis 時間: 2025-3-27 19:41 作者: 繁榮地區(qū) 時間: 2025-3-28 00:37 作者: prick-test 時間: 2025-3-28 03:25
Joachim Rüdiger D?hler FRCSedymphomas can be divided into two broad categories, follicular lymphomas and diffuse B or T small-cell lymphomas (Table 1). The clinical aggressiveness associated with the two categories of lymphomas, as well as the outcome of these patients, is variable. In some cases the lymphomas have very low cli作者: 核心 時間: 2025-3-28 09:40 作者: 思想靈活 時間: 2025-3-28 13:36
Joachim Rüdiger D?hler FRCSedsenting many stages of differentiation in the B-cell lineage is surprising and the possible mechanisms of action responsible for this activity remain an important subject for further investigation. This review describes the clinical results reported to date and discusses interferon’s potential role
