作者: 閑蕩 時間: 2025-3-21 21:42
overy and a better understanding of immune regulation of allergic airway inflammation. In this chapter we discuss our current understanding of immune regulation of airway inflammation in asthma, with a special focus on the interactions between the adaptive and innate immune systems and the epithelia作者: 拾落穗 時間: 2025-3-22 02:47 作者: 痛得哭了 時間: 2025-3-22 08:06 作者: 玷污 時間: 2025-3-22 11:01 作者: 小卷發(fā) 時間: 2025-3-22 14:45
Jutta Rump,Silke Eilersby increase of knowledge of the disease mechanisms. Although the etiology of these disorders is largely unknown, immunologic, hormonal, environmental, and genetic factors have been implicated. Adherence to endothelial cells in postcapillary venules (high endothelial venules: HEV) is an indispensable作者: 人造 時間: 2025-3-22 19:35 作者: 古老 時間: 2025-3-22 21:32
cytometry, but other technologies have emerged and include mass cytometry, multiplex immunohistochemistry, and single-cell RNA-sequencing. In this chapter we provide a detailed protocol to profile NK cells using flow cytometry, and a brief introduction to other techniques.作者: 粘 時間: 2025-3-23 04:45
Jutta Rump,Gudrun Thomas-Wolf,Gaby Wilms,Silke Eilersf antigenic stimulation and have the capacity to expand rapidly upon secondary challenges. Recently, with the identification of central and effector memory T cell subsets, tremendous efforts have been devoted to characterize markers on the surfaces of these cells. Though, various markers have been u作者: thyroid-hormone 時間: 2025-3-23 08:27
Christian Ahlringctional verification of the MHC-binding peptide using professional APCs, which are difficult to isolate, expand, and maintain. To address these issues, we have developed a facile, accurate, and high-throughput method for T cell epitope mapping by screening antigen-derived peptide libraries in comple作者: AGONY 時間: 2025-3-23 11:47
Marion Hodapp,Martin Peu?ereptors belonging to the Ig superfamily can recognize groups of HLA class I molecules, such as two distinct groups of HLA-C alleles (KIR2DL1, KIR2DL2, KIR2DL3, KIR2DS1, KIR2DS2), one group of B alleles displaying Bw4 supertypic specificity (KIR3DL1), and the HLA-A alleles, HLA-A3 and HLA-A11 (KIR3DL2作者: 有害處 時間: 2025-3-23 14:33
Michael Bohrmann,Fran?oise Fuchs,Sven Rottingernoreceptor tyrosine-based inhibitory motif (ITIM), with the consensus sequence of I/V/L/S-x-Y-x-x-V/L, which is the focus of this volume, was originally described in the cytoplasmic tails of the low affinity Fc receptor for IgG antibodies (FcγRUB) on B cells and the killer inhibitory receptors (KIR)作者: Rejuvenate 時間: 2025-3-23 21:27
Bettina Sabathal test of the direct contact hypothesis was possible in 1971, and no direct test has yet been performed. However, a test to determine whether effective help could occur without T-B contact was feasible in tissue culture, by separating T cells and B cells by a cell impermeable membrane, which nevert作者: abolish 時間: 2025-3-23 22:55 作者: 暗諷 時間: 2025-3-24 03:09 作者: CIS 時間: 2025-3-24 09:45
Lebensphasenorientierte Personalpolitik in der LBS Rheinland-Pfalz Lebensphasenorientierung erg?nzt. Ziel ist, die Mitarbeiter in die Lage zu versetzen, sich in jeder Lebensphase optimal in der LBS einbringen zu k?nnen..Anhand einer Reihe von Einzelbeispielen wird aufgezeigt, wie durch eine Grundhaltung der Flexibilit?t und Offenheit L?sungen gefunden werden, die 作者: 吝嗇性 時間: 2025-3-24 14:11 作者: Deceit 時間: 2025-3-24 15:33
F?rderung von Mitarbeiterengagement in verschiedenen Lebensphasen bei der Bundesagentur für Arbeitischer Anforderungen dar. Wichtig für Führungskr?fte ist es, die unterschiedlichen und sich ver?ndernden, altersspezifischen Bedürfnisse und Erwartungen der Besch?ftigten – also deren psychologische Vertr?ge - zu kennen und engagementf?rderlich zu gestalten. Ein bedeutendes Handlungsfeld ist dabei d作者: MUTED 時間: 2025-3-24 22:13 作者: 入會 時間: 2025-3-25 01:39
https://doi.org/10.1007/978-3-642-41665-1Best Practices; Demografie; Lebensphasenorientierte Personalpolitik; Vereinbarkeit作者: 占線 時間: 2025-3-25 03:29
Jutta Rump,Silke EilersHohe Praxisorientierung mit konkreten Umsetzungstipps.Ganzheitlicher Ansatz, der Wissenschaft und Praxis miteinander verzahnt.Hoher Innovationsgrad, da nicht nur der Stand der Diskussion wiedergegeben作者: jumble 時間: 2025-3-25 08:46
IBE-Reihehttp://image.papertrans.cn/l/image/583293.jpg作者: 口味 時間: 2025-3-25 13:06
978-3-642-41664-4Springer-Verlag Berlin Heidelberg 2014作者: sclera 時間: 2025-3-25 18:29 作者: biosphere 時間: 2025-3-25 20:21 作者: 興奮過度 時間: 2025-3-26 02:24
Der Berufs-Lebensbaummit den Bl?ttern jeweils von zwei Seiten bereichert: von der Mitarbeiterseite tragen die pers?nlichen Qualifikationen, Interessen und Anforderungen aufgrund der Lebenssituation zur Entwicklung bei, von der Unternehmensseite werden die zur Verfügung stehenden Ma?nahmen und Angebote in den einzelnen Lebensphasen bereitgestellt.作者: affluent 時間: 2025-3-26 05:48
Nah dran am ?richtigen“ Leben k?nnte man Personalarbeit 2.0 nennen. Oder ?Personalarbeit nah dran“. Bei der Commerzbank hei?t es Lebensphasenorientierte Personalarbeit. Es ist eine Philosophie, kein Projekt. Denn kompetente Personalarbeit im Spannungsfeld von Individuum und Unternehmen bildet weder eine Einstellung noch eine Checkliste ab.作者: lattice 時間: 2025-3-26 12:31
2199-269X onsgrad, da nicht nur der Stand der Diskussion wiedergegeben.Trends wie der demografische Wandel, technisch-?konomische Entwicklungen sowie der gesellschaftliche Wertewandel stellen Arbeitgeber wie Arbeitnehmer vor nicht unerhebliche Herausforderungen. Eine Lebensphasenorientierte Personalpolitik rü作者: 矛盾心理 時間: 2025-3-26 13:12 作者: 情感 時間: 2025-3-26 18:42 作者: debase 時間: 2025-3-26 22:23
?Strategie für die Zukunft – Lebensphasenorientierte Personalpolitik“ – Eine nachhaltige Erfolgsgescm einen zu praxisnahen Handlungsempfehlungen im Rahmen mehrerer Publikationen geführt und zum anderen einen intensiven Erfahrungsaustausch rheinland-pf?lzischer Betriebe zur Lebensphasenorientierten Personalpolitik und Fachkr?ftesicherung angesto?en hat.作者: AWE 時間: 2025-3-27 03:49 作者: Banquet 時間: 2025-3-27 07:50 作者: 遺傳 時間: 2025-3-27 12:29 作者: infarct 時間: 2025-3-27 16:58
ropriate activation of these immune systems in the respiratory mucosa results in chronic inflammatory airways disease such as asthma. Adaptive immunity is stimulated for example by allergen exposure that activates T and B lymphocytes leading to IgE production and influx of eosinophilic granulocytes 作者: 驕傲 時間: 2025-3-27 19:15
Jutta Rump,Gaby Wilms,Silke Eilersthey orchestrate a myriad of protective and destructive host responses during acute inflammation. Although neutrophils comprise the first line of defense against exogenous and endogenous insults, these abundantly produced white blood cells can damage tissues and consequently increase the severity of作者: FANG 時間: 2025-3-27 22:21
combating inflammation, their use is limited. This is caused by quality-of-life-threatening side effects, e.g. osteoporosis and metabolic imbalances. Contemporary efforts still focus on the development and characterization of novel (non-)steroidal ligands that can separate the beneficial anti-inflam作者: Tailor 時間: 2025-3-28 03:34
Jutta Rump Prof. Dr.,Silke Eilersrmalities in this network can result in autoimmunity, characterized by the emergence of lymphocyte clones and the synthesis of antibodies directed against the host’s own tissue. Although different pathogenic mechanisms may be involved in autoimmune diseases, many of their characteristics are common 作者: Neuropeptides 時間: 2025-3-28 08:06
Jutta Rump,Silke Eilersrmalities in this network can result in autoimmunity, characterized by the emergence of lymphocyte clones and the synthesis of antibodies directed against the host’s own tissue. Although different pathogenic mechanisms may be involved in autoimmune diseases, many of their characteristics are common 作者: 坦白 時間: 2025-3-28 13:55 作者: 他姓手中拿著 時間: 2025-3-28 18:35
r. Although cancer immunotherapy can result in long-lasting clinical responses, the majority of patients do not respond or develop resistance. Furthermore, cancer immunotherapy is being increasingly combined with other forms of immunotherapy or conventional cancer therapies. It is therefore much nee作者: GULP 時間: 2025-3-28 22:01
Jutta Rump,Gudrun Thomas-Wolf,Gaby Wilms,Silke Eilersre we describe flow cytometry-based method to characterize phenotype of na?ve, memory, and effector T cells. Being able to differentiate these cells is crucial in understanding immune response, and immune profiling. Na?ve T cells enable the body to fight off new, unrecognized infections and diseases作者: Blazon 時間: 2025-3-29 02:27 作者: 官僚統(tǒng)治 時間: 2025-3-29 04:20
Marion Hodapp,Martin Peu?er major role in innate immunity, as an early defense against a variety of infections and influence the development of acquired immunity. They also participate in the elimination of certain tumors and virally infected cells which have lost or downregulated their MHC class I molecules. This concept was作者: Nonconformist 時間: 2025-3-29 10:03 作者: incubus 時間: 2025-3-29 11:36
Bettina Sabathoitt et al., 1969, Greaves et al., 1972), the puzzle of Immune Response genes had been uncovered (Kantor et al., 1963) and receptor antibodies had been visualized on B cells but not T cells (Taylor et al., 1971). The carrier effect had been described and the phenomenon of linked recognition had sugg
