標(biāo)題: Titlebook: CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues; Philip Rubin (Professor Emeritus, Chair Emeritus), Book 2008 Springer-V [打印本頁] 作者: Suture 時間: 2025-3-21 17:29
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作者: overweight 時間: 2025-3-21 20:58 作者: Metamorphosis 時間: 2025-3-22 01:53 作者: 表否定 時間: 2025-3-22 06:33
Philip Rubin (Professor Emeritus, Chair Emeritus),This volume is based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006.Written by experts in the field, it addresses a number of critical topics relating to 作者: Mirage 時間: 2025-3-22 09:29
Medical Radiologyhttp://image.papertrans.cn/l/image/581766.jpg作者: botany 時間: 2025-3-22 14:24
Ionizing Radiation and the Endothelium,l or sublethal injury to EC. The latter may alter considerably the complex physiology of the endothelium. Some functions are inhibited or abolished: fibrinolysis, synthesis of various enzymes and cytokines, attachment of EC to the basal lamina, angiogenesis, etc.作者: intelligible 時間: 2025-3-22 17:10
Cancer-Related Fatigue as a Late Effect:,ive survey conducted in part to characterize CRF severity in relation to depression and shortness of breath and to compare symptom severity in radiation and chemotherapy patients and over time. Careful characterization of CRF will aid in the development of effective methods to manage this disabling symptom.作者: defibrillator 時間: 2025-3-23 01:12 作者: MODE 時間: 2025-3-23 04:37 作者: placebo 時間: 2025-3-23 08:14
CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues作者: Orgasm 時間: 2025-3-23 11:48 作者: crockery 時間: 2025-3-23 17:51 作者: 移植 時間: 2025-3-23 21:38 作者: Medicaid 時間: 2025-3-24 00:46
Christopher D. Willey MD, PhD,Dennis E. Hallahan MDA) and has confirmed the etiologic, face, and predictive validity of the model. The .-KO model thus serves as a unique platform to probe the pathophysiology of TS and related conditions, and to generate specific hypotheses for subsequent testing in humans. This chapter summarizes the development and作者: occult 時間: 2025-3-24 06:22
Richard P. Hill PhD,Mohammed A. Khan MD,Aimee R. Langan MD,Ivan W. T. Yeung MD,Jake Van Dyk MDpression in nasal hypersensitivity model rats through the suppression of PKCδ. Similar effects of antihistamines and antiallergic natural medicines support that histamine H. receptor-mediated activation of histamine H. receptor gene expression is an important signaling pathway for the symptoms of al作者: Collected 時間: 2025-3-24 08:37 作者: 仔細(xì)檢查 時間: 2025-3-24 14:13 作者: Oration 時間: 2025-3-24 14:55 作者: Salivary-Gland 時間: 2025-3-24 22:48
Eric P. Cohen MD,Melissa M. Joines BS,John E. Moulder PhDukaryotes. Such systems implicate a sensory histidine kinase and a separate response regulator protein. Both components exploit protein flexibility to effect specific conformational rearrangements, modulating protein–protein interactions, and ultimately transmitting information accurately. Recent wo作者: debunk 時間: 2025-3-25 03:11 作者: Brain-Waves 時間: 2025-3-25 05:35
Moyed Miften PhD,Olivier Gayou PhD,David S. Parda MD,Robert Prosnitz MD,Lawrence B. Marks MDnslocations that produce fusion proteins which activate . occur more frequently in ECD than in LCH. The presence of some of these activating mutations in circulating cells or in CD34+ bone marrow cells suggests that these diseases may arise from transforming events in early myeloid precursors. ICH c作者: 協(xié)迫 時間: 2025-3-25 08:06
Gary R. Morrow PhD, MS,Joseph A. Roscoe PhD,Maralyn E. Kaufman PhD,Christopher Bole MA,Colmar Figuers associated with hypomorphic and/or monoallelic mutations in genes encoding effectors of the lymphocyte cytotoxicity, has changed our view of HLH’s pathophysiology, in which the disease develops after the progressive accumulation of genetic and environmental factors exceeds a critical threshold.作者: 下船 時間: 2025-3-25 14:01
Philip Rubin MDnation. Biopsies of such lesions are rare. In the few published cases biopsied, variable pathologies are described with perivascular inflammatory changes, variable neuronal loss, demyelination, and gliosis, but are nondiagnostic for CD1a+/CD207+ LCH cells. Granulomatous LCH can be responsive to chem作者: Herbivorous 時間: 2025-3-25 19:19 作者: Limerick 時間: 2025-3-25 20:00 作者: Provenance 時間: 2025-3-26 03:51 作者: 讓空氣進(jìn)入 時間: 2025-3-26 04:40 作者: monologue 時間: 2025-3-26 11:31 作者: 慟哭 時間: 2025-3-26 13:58 作者: 終止 時間: 2025-3-26 20:16 作者: prosperity 時間: 2025-3-26 23:18
Melissa M. Hudson MD,Wendy Landier RN, MSN, CPNP, CPON,Smita Bhatia MD, MPH,Kevin C. Oeffinger MD,Chical properties and the therapeutic exploitation of HRs and their ligands. In addition, the range of techniques described provides an introduction to complementary cross-methodological disciplines beyond these fields. This multi-disciplinary approach is required to define the ‘decision gates’ that d作者: Glossy 時間: 2025-3-27 03:50 作者: Nibble 時間: 2025-3-27 07:49 作者: 單片眼鏡 時間: 2025-3-27 11:48 作者: SAGE 時間: 2025-3-27 17:12
Richard P. Hill PhD,Mohammed A. Khan MD,Aimee R. Langan MD,Ivan W. T. Yeung MD,Jake Van Dyk MDd. Levels of histamine H. receptor mRNA and IL-4 mRNA in nasal mucosa were elevated by the provocation of nasal hypersensitivity model rats. Pretreatment with antihistamines suppressed the elevation of mRNA levels. Scores of nasal symptoms were correlatively alleviated to the suppression level of mR作者: 異教徒 時間: 2025-3-27 21:40
Zafer Kocak MD,Lalitha Shankar MD, PhD,Daniel C. Sullivan MD, PhD,Lawrence B. Marks MDisolated as a bacterial contaminant of an extract of ergot (1910), the elucidation of its role in health and disease and its molecular mechanism of action have been continuous, reflecting the application of advances in scientific knowledge, technology and therapeutics over the last 100 years.. It ap作者: esoteric 時間: 2025-3-28 00:53 作者: 聽寫 時間: 2025-3-28 02:25
Mitchell Steven Anscher MD,Zeljko Vujaskovic MD, PhDpecific signals and execute predetermined responses. Such proteins constitute concerted systems that can be as simple as a unique protein, able to recognize a ligand and exert a phenotypic change, or extremely complex pathways engaging dozens of different proteins which act in coordination with feed作者: 有機(jī)體 時間: 2025-3-28 09:34
Eric P. Cohen MD,Melissa M. Joines BS,John E. Moulder PhDpecific signals and execute predetermined responses. Such proteins constitute concerted systems that can be as simple as a unique protein, able to recognize a ligand and exert a phenotypic change, or extremely complex pathways engaging dozens of different proteins which act in coordination with feed作者: Biofeedback 時間: 2025-3-28 13:45
Eric J. Hall DPhil, DSc, FACR, FRCR,David J. Brenner PhD, DSc their disease within 5 years, and the treatment of these patients has been a challenge and their outcome is very poor. Treatment failures in patients with low-risk LCH are not associated with mortality but with morbidity, and their optimal treatment is not well defined. Nucleoside analogues such as作者: BLINK 時間: 2025-3-28 17:18
Moyed Miften PhD,Olivier Gayou PhD,David S. Parda MD,Robert Prosnitz MD,Lawrence B. Marks MDfor the L Group histiocytoses, which include Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), and indeterminate cell histiocytosis (ICH). Although the phenotype of LCH histiocytes is distinct from that of ECD histiocytes and the clinical presentations of the pure forms of each dis作者: Graphite 時間: 2025-3-28 21:53 作者: Exaggerate 時間: 2025-3-29 01:34
Philip Rubin MD of clinical, imaging, and pathology findings, two patterns of CNS-LCH have been identified: granulomatous (“tumorous”) and non-granulomatous “neurodegenerative” (ND)-CNS-LCH. Granulomatous CNS-LCH can manifest with polyuria and polydipsia, seizures, increased intracranial pressure, or other signs, 作者: 占線 時間: 2025-3-29 03:51
Noreen M. Aziz MD, PhD, MPhneed to screen novel compounds for their potential therapeutic effects, and once these have been "discovered" to understand their molecular actions, as the basis of using such compounds safely and for rational drug design. Pharmacology now uses all of the sophisticated molecular research techniques 作者: Coronation 時間: 2025-3-29 10:47 作者: 造反,叛亂 時間: 2025-3-29 15:27
Radiation (and Medical) Biosurveillance,ealth-related quality of life. Progress by the (Children’s Oncology Group (COG) can be modeled or adapted for a adult malignancy, and is described in this report. Investigators from COG developed risk-based, exposure-related guidelines to provide recommendations for screening and management of late 作者: 雕鏤 時間: 2025-3-29 16:57
Medical Countermeasures to Radiation Injury,n, and treatment of radiation damage to normal tissue as a consequence of exposure of healthy populations, as well as from cancer treatment. The recent threat of radiological and nuclear terrorism as a consequence of a radiological dispersion device (RDD) or improvised nuclear device (IND) has raise作者: 過于平凡 時間: 2025-3-29 23:33 作者: arbovirus 時間: 2025-3-30 02:54 作者: Urea508 時間: 2025-3-30 07:44
The Role of Imaging in the Study of Radiation-Induced Normal Tissue Injury,es. One of the major challenges in the study of radiation (RT)-induced normal tissue injury is determining the appropriate endpoint. Patients’ symptoms have obvious clinical relevance; however, the scoring of symptoms is relatively subjective. Conversely, radiologic endpoints are potentially quantif作者: growth-factor 時間: 2025-3-30 09:44
Hypoxia-Mediated Chronic Normal Tissue Injury,cent progress in understanding the mechanisms underlying the development of late injury following cancer treatment points toward chronic hypoxia and oxidative stress as an important contributor to this problem. In this chapter, the authors review the evidence to support this new paradigm of late nor作者: infarct 時間: 2025-3-30 15:14
Prevention and Treatment of Radiation Injuries,hich act to attenuate the conversion of angiotensin I to angiotensin II, are beneficial in mitigating experimental renal, lung, or brain normal tissue radiation injury. The benefit of ACE inhibitors and angiotensin II blockers has been particularly well documented in experimental radiation nephropat作者: 符合規(guī)定 時間: 2025-3-30 18:23 作者: heirloom 時間: 2025-3-31 00:06
Using Quality of Life Information to Rationally, generally accepted method to compare and rank these competing treatment plans. A “realistic” approach utilizing decision analysis tools to rank treatment plans based on quality adjusted life years (QALY) expectancy was developed. The decision analysis methods were applied to the concept of uncompli作者: Deference 時間: 2025-3-31 01:23 作者: 參考書目 時間: 2025-3-31 07:19
Normal Tissue TNM Toxicity Taxonomy,mal tissue, then spread regionally into lymph nodes and then to systematic distant sites hematogenously. In a parallel fashion, the conceptual design of a normal tissue TNM classification is based on a similarity of normal tissue injury following multimodal cancer treatment which is often greatest i
