標(biāo)題: Titlebook: LC-MS in Drug Bioanalysis; Q. Alan Xu,Timothy L. Madden Book 2012 Springer Science+Business Media, LLC 2012 Bioanalysis.LC-MS.LC-MS/MS.Liq [打印本頁] 作者: 斷頭臺(tái) 時(shí)間: 2025-3-21 19:03
書目名稱LC-MS in Drug Bioanalysis影響因子(影響力)
書目名稱LC-MS in Drug Bioanalysis影響因子(影響力)學(xué)科排名
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書目名稱LC-MS in Drug Bioanalysis網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱LC-MS in Drug Bioanalysis被引頻次
書目名稱LC-MS in Drug Bioanalysis被引頻次學(xué)科排名
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書目名稱LC-MS in Drug Bioanalysis年度引用學(xué)科排名
書目名稱LC-MS in Drug Bioanalysis讀者反饋
書目名稱LC-MS in Drug Bioanalysis讀者反饋學(xué)科排名
作者: 本能 時(shí)間: 2025-3-21 22:12
Book 2012epileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.作者: 肌肉 時(shí)間: 2025-3-22 01:59 作者: 摘要記錄 時(shí)間: 2025-3-22 07:46 作者: RAFF 時(shí)間: 2025-3-22 10:56
Liquid Chromatography-Mass Spectrometry for the Determination of Antidepressants and Some of their used for these therapeutic drugs, as well as common chromatographic and mass spectrometric characteristics. In addition, an LC-MS/MS method for the most common antidepressants used in clinical practice is described as an example of a whole method development and validation.作者: 躺下殘殺 時(shí)間: 2025-3-22 13:10
Book 2012(MS), the high performance liquid chromatography – mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs anti作者: CRAB 時(shí)間: 2025-3-22 18:43
Internal Standards for Quantitative LC-MS Bioanalysis,al standard so that analyte losses and experimental variations during sample preparation, chromatographic separation, and mass spectrometric detection could be corrected? How is the concentration of an internal standard determined? Should internal standard responses be monitored during the analysis 作者: 貪婪的人 時(shí)間: 2025-3-23 01:06
Method Development, Validation, and Sample Analysis for Regulated Quantitative Bioanalysis Using LCt, method validation, and sample analysis including incurred sample reanalysis (ISR). Robust and rugged LC-MS/MS methods are essential in support of drug discovery, toxicology studies, and clinical trials. The development of a robust bioanalytical method requires careful consideration of many critic作者: JADED 時(shí)間: 2025-3-23 05:03 作者: 有助于 時(shí)間: 2025-3-23 06:55
Highly Sensitive Pharmaceutical and Clinical Analysis Using Selective Solid-Phase Extraction Coupledministration and quantification of low-abundance markers in circulating systems. Nonetheless, this task is highly challenging even for a LC-MS/MS approach, due to the extremely low levels of analytes and the highly complex matrices. Here we describe a robust method for the ultrasensitive quantifica作者: prosthesis 時(shí)間: 2025-3-23 09:49
Pitfalls of LC-MS/MS in the Clinical Laboratory,nical laboratories worldwide. It found its sound place amongst major basic routine technologies of laboratory medicine as enzyme based assays or immunoassays. LC-MS/MS extended the technological armamentarium of clinical laboratories significantly, both in analytical and economical terms. Especially作者: 揭穿真相 時(shí)間: 2025-3-23 14:25
Therapeutic Drug Monitoring to Support Clinical Pharmacogenomics,herapeutic drug monitoring is well accepted and widely practiced for many drugs and is also relevant for drugs for which pharmacogenomic testing is needed. Tamoxefin is metabolized by CYP 2D6 to endoxifen, clopidogrel by CYP 2C19 to thiol-containing active metabolite, and opioid drugs by 2D6 to morp作者: Glossy 時(shí)間: 2025-3-23 20:31
Liquid Chromatography-Mass Spectrometry for the Determination of Antidepressants and Some of their for identification and quantification of these therapeutic drugs should be available in clinical and toxicological laboratories. Improvements in liquid chromatography-mass spectrometry LC-MS(MS) technology over the last two decades have favored this technique to be one of the most commonly employed 作者: 值得贊賞 時(shí)間: 2025-3-24 01:09 作者: burnish 時(shí)間: 2025-3-24 05:03
Therapeutic Drug Monitoring of Targeted Anticancer Therapy. Tyrosine Kinase Inhibitors and Selectivapy to chronic oral treatment with targeted molecular therapies. Most oral anticancer-targeted drugs approved at present are tyrosine kinase inhibitors (TKIs) and some of them are accompanied with diagnostic test aiming at preselecting patients who are more likely to respond to anticancer treatment,作者: RAGE 時(shí)間: 2025-3-24 07:09
Applications of Mass Spectrometry in Analyses of Steroid Hormones,teroid hormones as biomarkers in endocrinology and pathology diagnoses, doping drugs in athletes and racing horses, residuals in food safety concerns, and environmental pollutants in water and sediments. Both liquid chromatography mass spectrometry (LC-MS or LC-MS/MS) and gas chromatography mass spe作者: 粗野 時(shí)間: 2025-3-24 10:56
Liquid Chromatography-Mass Spectrometric Analysis of Tropane Alkaloids in Mammalian Samples: Techninthetic drugs, most of them (e.g. atropine, benzatropine, .-butyl scopolamine, cimetropium, homatropine, ipratropium, .-methyl scopolamine, scopolamine, tiotropium, trospium) antagonizing acetylcholine at muscarinic receptors (MR) and some of them (e.g. bemesetron, granisetron, scopolamine, tropiset作者: 軍械庫 時(shí)間: 2025-3-24 17:51
Analysis of Illicit Drugs in Human Biological Samples by LC-MS,,tical strategy depending on the aim of the analysis and/or on the availability of the sample or on which kind of information is needed. Liquid chromatography–mass spectrometry (LC-MS or LC-MS/MS) has provided a helpful tool in this field especially for hydrophilic, thermolabile, and nonvolatile anal作者: ADORN 時(shí)間: 2025-3-24 21:32 作者: 剛毅 時(shí)間: 2025-3-25 02:19 作者: 帶來墨水 時(shí)間: 2025-3-25 04:23
es (text?and non-text) have been identified, the segmentation of the text elements can begin. Several challenges exist which need to be worked out in order to segment the elements correctly. For line segmentation, touching, broken, or overlapping text lines frequently occur. Handwritten documents ha作者: Generosity 時(shí)間: 2025-3-25 09:45
Aimin Tan,Nadine Boudreau,Ann Lévesqueth the shape, size, and style of the characters and symbols used in the formation of the text but also admixed with more crucial factors such as the forms and size of pages, layout of written text, spacing between text lines, design of characters, density of information, directionality of text compo作者: colostrum 時(shí)間: 2025-3-25 13:06
Min Meng Ph.D.,Patrick K. Bennettth the shape, size, and style of the characters and symbols used in the formation of the text but also admixed with more crucial factors such as the forms and size of pages, layout of written text, spacing between text lines, design of characters, density of information, directionality of text compo作者: Aphorism 時(shí)間: 2025-3-25 18:43
Jun Zhang Ph.D.,Ramona Rodila,Huaiqin Wu,Tawakol A. El-Shourbagys. Broadly speaking, infrastructure can be defined as the ‘social overhead capital’ of an economy (Hirschman, 1958), which is necessary for economic agents, for example firms, to start and conduct their activities (Frey, 1988). With a focus on the catching up of emerging and transition economies, an作者: 量被毀壞 時(shí)間: 2025-3-25 20:02
Haoying Yu,Xiaotao Duan,Jun Qu Ph.D.ribed as the transition from a system of ‘real Socialism’ towards a concept that can be subsumed under the terms of ‘democracy’ and ‘free market economy’. The 1990s were characterized by the onset of war, ‘ethnic cleansing’, mass rape and destruction for a considerable part of the region. In the las作者: GRE 時(shí)間: 2025-3-26 01:28
Christoph Seger Ph.D.,Michael Vogeser M.D.s. Broadly speaking, infrastructure can be defined as the ‘social overhead capital’ of an economy (Hirschman, 1958), which is necessary for economic agents, for example firms, to start and conduct their activities (Frey, 1988). With a focus on the catching up of emerging and transition economies, an作者: 不斷的變動(dòng) 時(shí)間: 2025-3-26 07:25
Alan H. B. Wu Ph.D.,Kara L. Lynch Ph.D.ferred to it, drawing either on Bourdieu (1980, 1984, 1986, 1993, 1996; among others). or on the rational choice theorist James S. Coleman (1988a, 1988b; among others).. The popularity of ‘social capital’ since the 1990s is due mainly to the political scientist Robert Putnam. His book on Italian civ作者: inclusive 時(shí)間: 2025-3-26 08:52 作者: Unsaturated-Fat 時(shí)間: 2025-3-26 14:53
Eva Saar,Dimitri Gerostamoulos,Olaf H. Drummer,Jochen Beyere such as radius of action, power, speed, transport capacity, independence of timing and choosing routes, etc. Unfortunately, the enormous kinetic energy involved in the dynamic process of driving is coupled with an inherent danger of loss of control..Both human factors and technical features of the作者: 施加 時(shí)間: 2025-3-26 18:31 作者: 盡責(zé) 時(shí)間: 2025-3-26 23:57 作者: Radiculopathy 時(shí)間: 2025-3-27 02:33
Harald Johnriments. This also includes the specification of required tools, equipment, boundary conditions, and evaluation methods..Test procedures are an essential tool to check whether desired product properties are present, which of course also applies to the development of driver assistance systems. In add作者: 符合你規(guī)定 時(shí)間: 2025-3-27 08:28 作者: 努力趕上 時(shí)間: 2025-3-27 11:33 作者: photopsia 時(shí)間: 2025-3-27 17:34 作者: MOTTO 時(shí)間: 2025-3-27 21:26
ch methodology.Promotes prevention science as an evolving fiThere are a number of reasons why this book is important. First, there is no one source that summarizes what we know about the prevention of substance abuse from the research field, so the book serves as a repository of accumulated knowledg作者: PRISE 時(shí)間: 2025-3-28 00:25 作者: jagged 時(shí)間: 2025-3-28 04:19 作者: Rebate 時(shí)間: 2025-3-28 08:51
Highly Sensitive Pharmaceutical and Clinical Analysis Using Selective Solid-Phase Extraction Couplegical matrix. By eliminating most undesirable matrix components, this selective SPE procedure enabled a high sample loading volume on the μLC column without compromising chromatographic performance and operational robustness, and helped to achieve ultralow detection limits. Sufficient μLC separation作者: 植物學(xué) 時(shí)間: 2025-3-28 13:21 作者: 秘密會(huì)議 時(shí)間: 2025-3-28 16:38
Therapeutic Drug Monitoring to Support Clinical Pharmacogenomics,b-therapeutic. TDM can also improve efficacy for tamoxifen for patients taking drug inhibitors, and be useful for determining the mechanism of clopidogrel resistance (i.e., pharmacokinetics vs. pharmacodynamics). Since there are no specific immunoassays for these drugs and metabolites for serum meas作者: 簡(jiǎn)潔 時(shí)間: 2025-3-28 22:26
The Analysis of Antipsychotic Drugs in Human Biosamples by LC-MS, This chapter reviews published multianalyte methods and highlights the important -criteria when developing an analytical method for the detection of APs, potential pitfalls, and the importance of appropriate method validation, in order to assure reproducibility of results.作者: 擴(kuò)大 時(shí)間: 2025-3-29 01:33
Therapeutic Drug Monitoring of Targeted Anticancer Therapy. Tyrosine Kinase Inhibitors and Selectivapeutic Drug Monitoring (TDM) approach, whereby the careful selection of TKI dosage is adapted to each patient according to individual plasma levels, contributing to minimize the risk of major adverse reactions and to increase the probability of efficient, long-lasting, therapeutic response. This ch作者: 血統(tǒng) 時(shí)間: 2025-3-29 04:30 作者: 厭食癥 時(shí)間: 2025-3-29 09:07 作者: 主講人 時(shí)間: 2025-3-29 15:11 作者: WITH 時(shí)間: 2025-3-29 17:19 作者: 極少 時(shí)間: 2025-3-29 22:02
for printed text, and styles for handwritten text bring new difficulties for segmentation and recognition algorithms..This chapter contains descriptions of some methodologies, presented from recent research, that propose solutions that overcome these obstacles. Line segmentation solutions include h作者: anachronistic 時(shí)間: 2025-3-30 02:29 作者: 混沌 時(shí)間: 2025-3-30 06:03
Min Meng Ph.D.,Patrick K. Bennettter recognition (OCR) and information retrieval technology. Considering the global upsurge of so-called minor and/or unknown languages, it has become a technological challenge to develop automatic or semiautomatic systems that can identify a language vis-à-vis a script in which a particular piece of作者: Innocence 時(shí)間: 2025-3-30 08:47
Jun Zhang Ph.D.,Ramona Rodila,Huaiqin Wu,Tawakol A. El-Shourbagyer, as infrastructure may induce higher economic growth rates, increases in the infrastructure endowment lead, ., to the larger market size of an economy. The market size of an economy is among the most important determinants in the investments of foreign firms (Bellak and Leibrecht, 2009).作者: 敘述 時(shí)間: 2025-3-30 13:46
Haoying Yu,Xiaotao Duan,Jun Qu Ph.D. state borders and the number of states did not remain the same during this period. From 1991 to 1992, the Socialist Federative Republic of Yugoslavia was dismembered through the recognition of Slovenia, Croatia, Bosnia and Herzegovina and Macedonia (officially called the ‘Former Yugoslav Republic o作者: CURB 時(shí)間: 2025-3-30 19:15 作者: 恫嚇 時(shí)間: 2025-3-30 23:49 作者: Ballerina 時(shí)間: 2025-3-31 01:32
Ana de Castro,Angelines Cruz,Manuel López-Rivadullailized during sublimation drying by the ice crystals. The shape of the dry substance is broadly the same as that of the frozen, wet substance and migration to the surface to form a skin is reduced. Since drying takes place at a low temperature, damage is minimized and volatile components are retaine作者: 向外 時(shí)間: 2025-3-31 05:07 作者: 袖章 時(shí)間: 2025-3-31 09:24
