標(biāo)題: Titlebook: Kinesins and Cancer; Frank Kozielski, FSB Book 2015 Springer Science+Business Media Dordrecht 2015 Cancer chemotherapy.Human mitotic kines [打印本頁(yè)] 作者: commotion 時(shí)間: 2025-3-21 18:01
書目名稱Kinesins and Cancer影響因子(影響力)
書目名稱Kinesins and Cancer影響因子(影響力)學(xué)科排名
書目名稱Kinesins and Cancer網(wǎng)絡(luò)公開(kāi)度
書目名稱Kinesins and Cancer網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書目名稱Kinesins and Cancer被引頻次
書目名稱Kinesins and Cancer被引頻次學(xué)科排名
書目名稱Kinesins and Cancer年度引用
書目名稱Kinesins and Cancer年度引用學(xué)科排名
書目名稱Kinesins and Cancer讀者反饋
書目名稱Kinesins and Cancer讀者反饋學(xué)科排名
作者: Overthrow 時(shí)間: 2025-3-21 22:43 作者: indices 時(shí)間: 2025-3-22 00:24 作者: FLAG 時(shí)間: 2025-3-22 05:36
Robert A. Cross1953), the HI emission of the Magellanic Clouds was observed from Australia. Largely as a result of the pioneering efforts of M.S. Roberts, by the time of his comprehensive review (Roberts 1975; the reader is referred to this source for the early development of the field), HI in about 140 extragalac作者: attenuate 時(shí)間: 2025-3-22 12:37
Steven S. Rosenfeldmed the subject from a phenomenological pursuit into an increasingly unified, physical science. High resolution centimetre, millimetre, infrared, and optical studies of local star forming clouds have allowed us to probe the physics of star formation down to spatial scales approaching those of the so作者: 罵人有污點(diǎn) 時(shí)間: 2025-3-22 15:08 作者: 小隔間 時(shí)間: 2025-3-22 21:06 作者: Synthesize 時(shí)間: 2025-3-23 00:34
Vaishali Pannu,Padmashree C. G. Rida,Ritu Anejay.Discusses the role of magnetic fields in the evolution of This course-tested textbook conveys the fundamentals of magnetic fields and relativistic plasma in diffuse cosmic media, with a primary focus on phenomena that have been observed at different wavelengths. Theoretical concepts are addressed 作者: eulogize 時(shí)間: 2025-3-23 04:50 作者: murmur 時(shí)間: 2025-3-23 08:25 作者: OTHER 時(shí)間: 2025-3-23 13:18
Brigitte L. Thériault,Timothy W. Corsonrder to investigate the spatial distribution of these two types of physically variable stars in the galaxy. The work was intended to be complete down to a photographic magnitude of 13.14 at maximum ligth for all stars officially named and classified as Mira or SRa (period > 95 days) in the General C作者: 吵鬧 時(shí)間: 2025-3-23 15:00 作者: magnanimity 時(shí)間: 2025-3-23 19:47 作者: Melatonin 時(shí)間: 2025-3-24 00:24
Mechanisms of Action of Eg5 Inhibitors,fluences motor activity largely by influencing the dynamics of nucleotide exchange, but surprisingly, whilst the residue requirements in the motor and the structure-activity relationships for the inhibitors have been examined by several groups, the allosteric molecular mechanisms by which inhibitors作者: 繁殖 時(shí)間: 2025-3-24 03:10 作者: micronutrients 時(shí)間: 2025-3-24 09:10 作者: Panacea 時(shí)間: 2025-3-24 13:53 作者: 變化 時(shí)間: 2025-3-24 18:29 作者: 通知 時(shí)間: 2025-3-24 19:55
Kinesin-13 Microtubule Depolymerizing Proteins as Targets for Cancer Therapy,al drug targets that may be similarly effective yet have fewer side effects. The known activities of kinesin-13 family members to promote spindle bipolarity and faithful chromosome segregation, along with their ability to influence microtubule behavior, suggest that these proteins would be particula作者: 生來(lái) 時(shí)間: 2025-3-25 02:38 作者: 光明正大 時(shí)間: 2025-3-25 07:08 作者: 明確 時(shí)間: 2025-3-25 08:42 作者: 粘連 時(shí)間: 2025-3-25 15:31
The Kinesin-6 Members MKLP1, MKLP2 and MPP1,bers have been characterised primarily because of their role in cell division, where they contribute to the regulation of the cytokinetic machinery as cells exit mitosis. Here we discuss the mechanisms by which MKLP1, MKLP2 and MPP1 regulate events during cell division and in post-mitotic tissues, h作者: GRIEF 時(shí)間: 2025-3-25 15:56
Non-motor Spindle Proteins as Cancer Chemotherapy Targets,ion. Both motor and non-motor microtubule associated proteins (MAPs) promote the assembly and disassembly of spindle microtubules during mitosis. Non-motor proteins localize to distinct subcellular sites, such as kinetochores and centrosomes, during different phases of mitosis. They are responsible 作者: flavonoids 時(shí)間: 2025-3-25 21:33 作者: Disk199 時(shí)間: 2025-3-26 02:34 作者: 過(guò)濾 時(shí)間: 2025-3-26 06:00 作者: 樂(lè)章 時(shí)間: 2025-3-26 08:54
Mechanisms of Action of Eg5 Inhibitors,ral mechanisms by which allosteric Eg5 inhibitors inhibit motor activity. I suggest that current Eg5 inhibitors work predominantly by stabilising the active site Mg. ion, and that they do this by stabilising the loop L5 in an apo-like conformation.作者: 敲竹杠 時(shí)間: 2025-3-26 15:19
Chromokinesins in Genome Maintenance and Cancer,apter we review the current knowledge of the structure, function and potential role of chromokinesins in cancer as well as the promise of this class of kinesins as candidate targets for therapeutic strategies.作者: 小母馬 時(shí)間: 2025-3-26 16:48
The Human Kinesin-14 Motor KifC1/HSET Is an Attractive Anti-cancer Drug Target,vations raise the tantalizing possibility that targeting HSET might be a promising cancer-selective chemotherapeutic approach. In this chapter, we summarize the multiple cellular roles played by HSET in various model systems and enumerate the steps required to validate and develop HSET as an anti-cancer drug target.作者: Decibel 時(shí)間: 2025-3-26 22:04
Kinesin-13 Microtubule Depolymerizing Proteins as Targets for Cancer Therapy,rly effective targets for drug development. This chapter reviews the activities of kinesin-13 proteins in the context of how they might be manipulated to affect spindle structure and advance cancer treatment by direct targeting, by enhancing the effectiveness of other current treatments, or by reversing resistance to other treatments.作者: 脾氣暴躁的人 時(shí)間: 2025-3-27 04:31 作者: 逃避系列單詞 時(shí)間: 2025-3-27 07:38
evance of kinesins to cancer treatment.Contributes to potent.This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting t作者: backdrop 時(shí)間: 2025-3-27 11:08 作者: 北極人 時(shí)間: 2025-3-27 15:11
Kif15: A Useful Target for Anti-cancer Therapy?, to the central player in mediating Eg5-independent bipolar spindle assembly. In this chapter, we describe the function of Kif15 during mitosis and discuss if Kif15 could be a target for drug development in anticancer therapy.作者: heterogeneous 時(shí)間: 2025-3-27 20:30
Kinesin-8 Members and Their Potential as Biomarker or Therapeutic Target, the increased abundance may reflect a higher percentage of proliferative cells. Reduction of Kinesin-8 delays cells in mitosis and perturbs microtubule dynamics. Inhibitors of Kinesin-8 may therefore influence the proliferative capacity or may impair the migratory potential of cancer cells. These ideas remain to be tested.作者: indecipherable 時(shí)間: 2025-3-27 23:06
Clinical Trials of Mitotic Kinesin Inhibitors,nd less toxic inhibitors of the mitotic process. In this chapter, I review the clinical experience with one group of inhibitors that target mitotic kinesins. I will discuss the results of phase I and II trials with these drugs and place the results of these trials in a context to explain how they can be utilized in future human studies.作者: Pageant 時(shí)間: 2025-3-28 02:36 作者: minimal 時(shí)間: 2025-3-28 08:16 作者: OCTO 時(shí)間: 2025-3-28 11:14
978-94-024-0365-7Springer Science+Business Media Dordrecht 2015作者: progestogen 時(shí)間: 2025-3-28 17:44 作者: 常到 時(shí)間: 2025-3-28 18:57 作者: plasma-cells 時(shí)間: 2025-3-29 02:13
James A. D. Good,Giacomo Berretta,Nahoum G. Anthony,Simon P. Mackayechniques of spectral line aperture synthesis, developed especially at Cambridge, Green Bank, and Owens Valley, bloomed in full maturity at Westerbork and more recently at the VLA. The contributions of single-dish instruments have, however, remained important, especially for survey-oriented projects作者: Virtues 時(shí)間: 2025-3-29 06:30 作者: Accomplish 時(shí)間: 2025-3-29 07:23
Roy G. H. P. van Heesbeen,René H. Medemare structure of this NATO Advanced Study Institute was designed to explore this new view of the subject. This Institute on "Galactic and Extragalactic Star Formation" was held from June 21 -July 4, 1987 at the Conference Centre in the village of Whistler, British Columbia, Canada. The informal atmos作者: 攝取 時(shí)間: 2025-3-29 14:18 作者: Armada 時(shí)間: 2025-3-29 19:16 作者: 沙漠 時(shí)間: 2025-3-29 20:31 作者: 縮減了 時(shí)間: 2025-3-30 01:49 作者: 殘忍 時(shí)間: 2025-3-30 07:16 作者: 粗魯?shù)娜?nbsp; 時(shí)間: 2025-3-30 11:03 作者: Affiliation 時(shí)間: 2025-3-30 14:05 作者: Limerick 時(shí)間: 2025-3-30 17:10
Inhibitors of Mitotic Kinesins for Cancer Treatment: Consequences for Neurons,therapies, focusing on proteins believed to be vital for successful mitosis but irrelevant to other cellular events. Such targets include a category of kinesins believed to be mitosis-specific. However, recent studies indicate that these so-called mitotic kinesins are also expressed in terminally po作者: TEN 時(shí)間: 2025-3-30 22:08 作者: catagen 時(shí)間: 2025-3-31 03:47 作者: 不可知論 時(shí)間: 2025-3-31 05:33
Steven S. Rosenfeldragalactic Star Formation" was held from June 21 -July 4, 1987 at the Conference Centre in the village of Whistler, British Columbia, Canada. The informal atmos978-94-010-7835-1978-94-009-2973-9Series ISSN 1389-2185 作者: radiograph 時(shí)間: 2025-3-31 12:04 作者: charisma 時(shí)間: 2025-3-31 14:21
