標(biāo)題: Titlebook: Kinase Screening and Profiling; Methods and Protocol Hicham Zegzouti,Said A. Goueli Book 2016 Springer Science+Business Media New York 2016 [打印本頁(yè)] 作者: 門(mén)牙 時(shí)間: 2025-3-21 16:44
書(shū)目名稱(chēng)Kinase Screening and Profiling影響因子(影響力)
書(shū)目名稱(chēng)Kinase Screening and Profiling影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)Kinase Screening and Profiling網(wǎng)絡(luò)公開(kāi)度
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書(shū)目名稱(chēng)Kinase Screening and Profiling被引頻次
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書(shū)目名稱(chēng)Kinase Screening and Profiling讀者反饋
書(shū)目名稱(chēng)Kinase Screening and Profiling讀者反饋學(xué)科排名
作者: 取回 時(shí)間: 2025-3-21 21:48
Recombinant Kinase Production and Fragment Screening by NMR Spectroscopy,lar interaction between the protein and the ligand, and has many advantages in fragment screening over other biophysical techniques. This chapter describes the practical aspects of fragment screening by saturation transfer difference NMR.作者: enfeeble 時(shí)間: 2025-3-22 02:23
Genetically Encoded Fluorescent Indicators to Visualize Protein Phosphorylation in Living Cells,visualizing the protein phosphorylation in living cells. Using these indicators, we visualized under a fluorescence microscope when, where, and how the protein kinases are activated in single living cells.作者: 表皮 時(shí)間: 2025-3-22 05:39 作者: 周年紀(jì)念日 時(shí)間: 2025-3-22 08:51 作者: Ophthalmologist 時(shí)間: 2025-3-22 12:57
Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Formacan be coupled to FLuc through a two-step process. This chapter describes the bioluminescent assays that were developed for three classes of kinases (lipid, protein, and metabolic kinases) and miniaturized to 1536-well format, enabling their use for quantitative high-throughput (qHTS) of small-molecule libraries.作者: 外貌 時(shí)間: 2025-3-22 19:16
A High-Content Assay to Screen for Modulators of EGFR Function,on are imaged and quantified using time-dependent granule formation in cells. This method can readily be used to search for EGFR modulators in both chemical and RNAi screening; with potential applicability to other receptor tyrosine kinases.作者: BOOM 時(shí)間: 2025-3-22 21:53 作者: Irksome 時(shí)間: 2025-3-23 04:45 作者: 通便 時(shí)間: 2025-3-23 06:56 作者: 裂隙 時(shí)間: 2025-3-23 12:09
Determination of the Substrate Specificity of Protein Kinases with Peptide Micro- and Macroarrays,ty using an approach that involves both peptide microarrays and macroarrays. In particular, SPOT synthesis on macroarrays can be used to follow up on in silico predictions of protein kinase substrate specificity with predictive algorithms.作者: 頌揚(yáng)國(guó)家 時(shí)間: 2025-3-23 14:49
Rapid Identification of Protein Kinase Phosphorylation Site Motifs Using Combinatorial Peptide Librquence is determined from the relative rate of phosphorylation of each peptide in the array. Consensus peptides based on these sequences typically serve as efficient and specific kinase substrates for high-throughput screening or incorporation into biosensors.作者: Haphazard 時(shí)間: 2025-3-23 20:37 作者: 閃光你我 時(shí)間: 2025-3-23 23:21
Methods in Molecular Biologyhttp://image.papertrans.cn/k/image/542734.jpg作者: intuition 時(shí)間: 2025-3-24 03:46
https://doi.org/10.1007/978-1-4939-3073-9ATP competitive inhibitors; assay development; cellular differentiation; cellular growth; cellular toxic作者: moratorium 時(shí)間: 2025-3-24 07:23 作者: 切割 時(shí)間: 2025-3-24 11:23
Kinase Screening and Profiling978-1-4939-3073-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 背景 時(shí)間: 2025-3-24 15:46
hes for quality solutions, applying various techniques in order to find the optimum (least cost) or semi optimum solution. Moreover, there are many different extensions and modifications of the original problem, The Time Dependent Traveling Salesman Problem (TD TSP) is a prime example. TD TSP indeed作者: xanthelasma 時(shí)間: 2025-3-24 22:37 作者: CLOWN 時(shí)間: 2025-3-25 01:00
Clint D. J. Tavares,Ashwini K. Devkota,Kevin N. Dalby,Eun Jeong Choecision makers who give the judgments of the item as comparison matrices on the viewpoints, it is reasonable that the weight vector of the item is the core of those by all the decision makers. Each decision maker’s weight vector basically includes his/her given comparison matrix, which represents on作者: 爭(zhēng)吵 時(shí)間: 2025-3-25 04:38 作者: 檢查 時(shí)間: 2025-3-25 09:46
Mindy I. Davis,Douglas S. Auld,James Ingleseberschreiben. Teilweise verlief diese Entwicklung sehr natürlich, teilweise gab es jedoch auch sehr unerwartete Sprünge. M?chte man die bisherige 25-j?hrige Entwicklung auf diesem Gebiet ganz grob strukturieren, so k?nnte man sie vielleicht einteilen in eine Phase der theoretischen Entwicklung, die 作者: 驚惶 時(shí)間: 2025-3-25 14:52
Hicham Zegzouti,Jacquelyn Hennek,Said A. Goueliberschreiben. Teilweise verlief diese Entwicklung sehr natürlich, teilweise gab es jedoch auch sehr unerwartete Sprünge. M?chte man die bisherige 25-j?hrige Entwicklung auf diesem Gebiet ganz grob strukturieren, so k?nnte man sie vielleicht einteilen in eine Phase der theoretischen Entwicklung, die 作者: Vulvodynia 時(shí)間: 2025-3-25 17:20
Andrew W. Tai,Jolanta Vidugirieneberschreiben. Teilweise verlief diese Entwicklung sehr natürlich, teilweise gab es jedoch auch sehr unerwartete Sprünge. M?chte man die bisherige 25-j?hrige Entwicklung auf diesem Gebiet ganz grob strukturieren, so k?nnte man sie vielleicht einteilen in eine Phase der theoretischen Entwicklung, die 作者: 漂亮 時(shí)間: 2025-3-25 20:38 作者: intertwine 時(shí)間: 2025-3-26 02:34
Christophe Antczak,Hakim Djaballah Ph.D., CEOourse. Anyway, it lacked to clarify the same concept of meaning in a way able to separate those words that can be submitted to scientific scrutiny from those that cannot, as well as to show which it is, into meaning, the actual role of the membership function of a fuzzy set. Once rooted in the Wittg作者: 充氣球 時(shí)間: 2025-3-26 08:07 作者: 一美元 時(shí)間: 2025-3-26 10:42 作者: Benign 時(shí)間: 2025-3-26 14:17 作者: Tremor 時(shí)間: 2025-3-26 19:24 作者: BOAST 時(shí)間: 2025-3-27 00:57
Thi B. Trinh,Dehua PeiInnerhalb der Mathematik geht diese Kritik auf L. E. J. Brouwer und seine Schüler A. Heyting und H. Weyl zurück, die sich gegen die naive Verwendung des Begriffs des AktualUnendlichen in der Mengenlehre wenden. In der Physik werden, im Gegensatz zur Mathematik, diese Bedenken nicht unmittelbar formu作者: right-atrium 時(shí)間: 2025-3-27 01:33 作者: Ataxia 時(shí)間: 2025-3-27 07:20
Chad J. Miller,Benjamin E. TurkInnerhalb der Mathematik geht diese Kritik auf L. E. J. Brouwer und seine Schüler A. Heyting und H. Weyl zurück, die sich gegen die naive Verwendung des Begriffs des AktualUnendlichen in der Mengenlehre wenden. In der Physik werden, im Gegensatz zur Mathematik, diese Bedenken nicht unmittelbar formu作者: 搏斗 時(shí)間: 2025-3-27 11:29
Innerhalb der Mathematik geht diese Kritik auf L. E. J. Brouwer und seine Schüler A. Heyting und H. Weyl zurück, die sich gegen die naive Verwendung des Begriffs des AktualUnendlichen in der Mengenlehre wenden. In der Physik werden, im Gegensatz zur Mathematik, diese Bedenken nicht unmittelbar formu作者: 整頓 時(shí)間: 2025-3-27 16:43 作者: Initiative 時(shí)間: 2025-3-27 18:07 作者: angiography 時(shí)間: 2025-3-27 23:39 作者: Dealing 時(shí)間: 2025-3-28 03:11
Bioluminescence Methods for Assaying Kinases in Quantitative High-Throughput Screening (qHTS) Formafirefly luciferases (FLuc) and kinases share a common substrate (ATP), coupling of a kinase to FLuc allows for the amount of ATP remaining following a kinase reaction to be assessed by quantitating the amount of luminescence produced. Alternatively, the amount of ADP produced by the kinase reaction 作者: Admonish 時(shí)間: 2025-3-28 08:33 作者: GRAIN 時(shí)間: 2025-3-28 13:01 作者: 繁榮中國(guó) 時(shí)間: 2025-3-28 17:16 作者: 完成才能戰(zhàn)勝 時(shí)間: 2025-3-28 22:35 作者: Stress 時(shí)間: 2025-3-29 02:43 作者: CRANK 時(shí)間: 2025-3-29 04:56
From Enzyme to Whole Blood: Sequential Screening Procedure for Identification and Evaluation of p38ccess of anti-cytokine therapy for treatment of inflammatory processes qualified p38-MAPK as a solid target in drug research concerning chronic inflammatory diseases including infectious vascular, neurobiological, and autoimmune disorders. However, the discovery of new kinase inhibitors is limited b作者: Pulmonary-Veins 時(shí)間: 2025-3-29 08:44 作者: Deject 時(shí)間: 2025-3-29 14:23 作者: Encumber 時(shí)間: 2025-3-29 17:54 作者: sperse 時(shí)間: 2025-3-29 21:32 作者: 相反放置 時(shí)間: 2025-3-30 02:49 作者: ingenue 時(shí)間: 2025-3-30 07:25
aveling Salesman Problem); which is an extension of the classic TD TSP with the additional notion of intuitionistic fuzzy sets. Our core concept is to employ intuitionistic fuzzy sets of the cost between nodes to quantify traffic jam regions, and the rush hour periods. Since the intuitionistic fuzzy作者: negligence 時(shí)間: 2025-3-30 11:31
Yong Jia,Mari Manuia,Jose Juarezsistent interval pairwise comparison matrix. In this paper, we show that the previous alternative estimation methods do not satisfy some of those properties and propose novel interval weight estimation methods satisfying those five requirements. The non-uniqueness of optimal normalized interval weig作者: ovation 時(shí)間: 2025-3-30 14:34
Clint D. J. Tavares,Ashwini K. Devkota,Kevin N. Dalby,Eun Jeong Choideration from the aspect of consistency of his/her judgments. We define a fuzzy degree of the consistency with all the comparison matrices s/he gives. As the consistency degree for a comparison matrix increases, it may become unable to satisfy the inclusion relation between the comparison matrix an作者: cortisol 時(shí)間: 2025-3-30 17:25 作者: connoisseur 時(shí)間: 2025-3-31 00:35
Mindy I. Davis,Douglas S. Auld,James Inglesealber kurz im folgenden getrennt skizziert und exemplarisch an Ver?ffentlichungen und Produkten illustriert werden. Es sei an dieser Stelle besonders betont, da? hierbei auf keinen Fall eine Vollst?ndigkeit der Literaturdarstellung angestrebt wird. Dies ist bei den heutzutage existierenden mehr als 作者: 爭(zhēng)議的蘋(píng)果 時(shí)間: 2025-3-31 02:12 作者: 使絕緣 時(shí)間: 2025-3-31 08:40
Andrew W. Tai,Jolanta Vidugirienealber kurz im folgenden getrennt skizziert und exemplarisch an Ver?ffentlichungen und Produkten illustriert werden. Es sei an dieser Stelle besonders betont, da? hierbei auf keinen Fall eine Vollst?ndigkeit der Literaturdarstellung angestrebt wird. Dies ist bei den heutzutage existierenden mehr als 作者: 漂亮 時(shí)間: 2025-3-31 11:51
Krisna C. Duong-Ly,Jeffrey R. Petersoninformation, notably in the form of linguistic data summaries as proposed by Kacprzyk and Zadro?ny. Here, we extend our approach with a new concept of an ideal and anti-ideal agent and option, though we will concentrate of the case of the ideal and anti-ideal agent as it is more intuitively appealin作者: CLAMP 時(shí)間: 2025-3-31 14:43
Christophe Antczak,Hakim Djaballah Ph.D., CEO logic was theoretically introduced, from the mid-sixties to the last eighties of the XX century, crisp deductive logic ideas were prevalent over those of conjectural ordinary reasoning to represent, for instance, what is ‘not properly covered under a linguistic label’ and only the concept of pseudo
