標(biāo)題: Titlebook: Islets of Langerhans; Md. Shahidul Islam Living reference work 20200th edition [打印本頁] 作者: 板條箱 時間: 2025-3-21 18:46
書目名稱Islets of Langerhans影響因子(影響力)
書目名稱Islets of Langerhans影響因子(影響力)學(xué)科排名
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書目名稱Islets of Langerhans網(wǎng)絡(luò)公開度學(xué)科排名
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書目名稱Islets of Langerhans被引頻次學(xué)科排名
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書目名稱Islets of Langerhans年度引用學(xué)科排名
書目名稱Islets of Langerhans讀者反饋
書目名稱Islets of Langerhans讀者反饋學(xué)科排名
作者: BILL 時間: 2025-3-21 21:43 作者: Pelvic-Floor 時間: 2025-3-22 03:01
Anionic Transporters and Channels in Pancreatic Islet Cells,ulin release, the present chapter, which deals with anionic transporters and channels in pancreatic islet cells, concerns mainly a second modality for the control of insulin secretion by the hexose. In such a perspective, it draws attention to the NBCe1 Na./HCO.. cotransporters, the volume-regulated作者: Heretical 時間: 2025-3-22 04:40
,Apoptosis in Pancreatic β-Islet Cells in Type 1 and Type 2 Diabetes,utoimmune insulitis causes an absolute insulin deficiency triggered by an extrinsic receptor-mediated pathway, which activates a cascade of caspase family reaction. The etiology of type 2 diabetes is multifactorial, including obesity-associated insulin resistance, defective insulin secretion, and lo作者: 啤酒 時間: 2025-3-22 11:48
Approaches for Imaging Pancreatic Islets: Recent Advances and Future Prospects,ther in vitro studies or quite indirect in vivo measurements. Methods to noninvasively and repeatedly evaluate the mass and function of β-cells in vivo, two parameters that are central to the study of diabetes, are expected to change our understanding of this disease. However, and in spite of remark作者: SNEER 時間: 2025-3-22 14:48
ATP-Sensitive Potassium Channels in Health and Disease, β-cell is finely balanced; increased activity prevents insulin secretion, whereas reduced activity stimulates insulin release. B-cell metabolism tightly regulates K. channel gating, and if this coupling is perturbed, two distinct disease states can result. Diabetes occurs when the K. channel fails 作者: Saline 時間: 2025-3-22 20:48 作者: SPALL 時間: 2025-3-22 23:06
Beta Cell Store-Operated Ion Channels,lation trigger Ca.-dependent signaling pathways that regulate insulin exocytosis. Much is known about ATP-sensitive K. and voltage-gated Ca. currents that contribute to Ca.-dependent signal transduction in β-cells and insulin secretion, but relatively little is known about other Ca. channels that re作者: pulse-pressure 時間: 2025-3-23 03:21
Calcium Signaling in the Islets,that have clarified details of Ca. signaling in the rodent islets. Our understanding of the mechanisms and the roles of Ca. signaling in the human islets, under physiological conditions, has been influenced by extrapolation of the rodent data obtained under suboptimal experimental conditions. More r作者: BRAND 時間: 2025-3-23 06:07
Chloride Channels and Transporters in Beta-Cell Physiology,e of additional ionic cascades of events within the stimulus-secretion coupling. The purpose of this review is to introduce the reader to the role of the long-relegated and largely ignored subject of intracellular Cl. concentration ([Cl.].). The regulation of [Cl.]. by transporters and channels, and作者: Entirety 時間: 2025-3-23 15:54
,Clinical Approaches to Preserving β-Cell Function in Diabetes,the time of diagnosis and there was a reduction of β-cell mass of about 60 % at necropsy (accelerated apoptosis). Among the interventions to preserve the β-cells, those that lead to short-term improvement of β-cell secretion are weight loss, metformin, sulfonylureas, and insulin. Long-term improveme作者: CHASM 時間: 2025-3-23 19:05 作者: Arresting 時間: 2025-3-23 23:15
Electrical, Calcium, and Metabolic Oscillations in Pancreatic Islets, bursting. We discuss the underlying mechanisms for bursting oscillations in mouse islets and the parallel oscillations in intracellular calcium and metabolism. We present a unified biophysical model, called the dual oscillator model, in which fast electrical oscillations are due to the feedback of 作者: meretricious 時間: 2025-3-24 03:58
Electrophysiology of Islet Cells,abolism-dependent alterations in ion channel activity..This coupling is best explored in beta cells. The effect of glucose is directly linked to mitochondrial metabolism as the ATP/ADP ratio determines the open probability of ATP-sensitive K. channels .K. channels). Nucleotide sensitivity and concen作者: MOTIF 時間: 2025-3-24 07:11 作者: saphenous-vein 時間: 2025-3-24 10:59 作者: 易于 時間: 2025-3-24 18:25 作者: 暫時過來 時間: 2025-3-24 19:33
,High-Fat Programming of β-Cell Dysfunction,r insult during critical periods of life which includes fetal and subsequent early neonatal life. Programming alters progeny physiology and metabolism with immediate, transient, and durable effects. Maternal nutrition and metabolic state in gestation and lactation shapes progeny development and heal作者: 間接 時間: 2025-3-25 01:13 作者: fetter 時間: 2025-3-25 04:13 作者: nullify 時間: 2025-3-25 08:52
Haruo Kasai,Hiroyasu Hatakeyama,Mitsuyo Ohno,Noriko Takahashing vornehmlich abzielt auf das Gebiet der Topographie und Kartographie. Hier gibt es auf unserem Planeten in der Tat noch viel zu tun und hier wird das photographische Me?verfahren sich auch bew?hren, vorausgesetzt, da? ihm die Ziele richtig gesteckt werden (Ziffer 3). Unter dieser Voraussetzung ist作者: 不妥協(xié) 時間: 2025-3-25 14:18
Blair K. Gage,Rhonda D. Wideman,Timothy J. Kiefferng vornehmlich abzielt auf das Gebiet der Topographie und Kartographie. Hier gibt es auf unserem Planeten in der Tat noch viel zu tun und hier wird das photographische Me?verfahren sich auch bew?hren, vorausgesetzt, da? ihm die Ziele richtig gesteckt werden (Ziffer 3). Unter dieser Voraussetzung ist作者: 溝通 時間: 2025-3-25 15:58
Marlon E. Cerfng vornehmlich abzielt auf das Gebiet der Topographie und Kartographie. Hier gibt es auf unserem Planeten in der Tat noch viel zu tun und hier wird das photographische Me?verfahren sich auch bew?hren, vorausgesetzt, da? ihm die Ziele richtig gesteckt werden (Ziffer 3). Unter dieser Voraussetzung ist作者: Control-Group 時間: 2025-3-25 22:51 作者: 特別容易碎 時間: 2025-3-26 02:50
Living reference work 20200th editionadvances made in the respective fields, but also provide directions and thoughts for future research. Thanks to vivid and colorful illustrations, tables and sketches, the book as a whole, and the individual chapters make reading a pleasant experience. If you are interested in diabetes research, you 作者: aesthetician 時間: 2025-3-26 07:07 作者: 安定 時間: 2025-3-26 09:22
,Apoptosis in Pancreatic β-Islet Cells in Type 1 and Type 2 Diabetes, genes (Bad, Bid, and Bik) and the anti-apoptotic Bcl family toward apoptosis in in vitro isolated islets. Apoptosis can only occur when the concentration of pro-apoptotic Bcl-2 exceeds that of anti-apoptotic proteins at the mitochondrial membrane of the intrinsic pathway..The bulk of recent researc作者: 詼諧 時間: 2025-3-26 13:12 作者: 使混合 時間: 2025-3-26 17:46
Beta Cell Store-Operated Ion Channels,cular mechanisms remain undefined. In this chapter, we provide both an overview of our current understanding of ionic currents regulated by ER Ca. stores in insulin-secreting cells and a review of studies in other cell systems that have identified the molecular basis and regulation of SOCE.作者: 儀式 時間: 2025-3-26 22:23
Calcium Signaling in the Islets,to be learnt about the mechanisms of generation and decoding of Ca. signals, much de-learning will also be needed. Human β-cells do not have a resting state in the normal human body even under physiological fasting conditions. Their membrane potential under physiologically relevant resting condition作者: 跳動 時間: 2025-3-27 03:46 作者: 油膏 時間: 2025-3-27 05:31
,Clinical Approaches to Preserving β-Cell Function in Diabetes,agonists (GLP-1 mimetics), not inactivated by the enzyme dipeptidyl peptidase-4, and/or to inhibit that enzyme (GLP-1 enhancers). The incretin hormones are released from the gastrointestinal tract in response to nutrient ingestion to enhance glucose-dependent insulin secretion from the pancreas and 作者: Prologue 時間: 2025-3-27 09:27
Electrophysiology of Islet Cells,ent Na. and/or Ca. channels and repolarized by voltage- and/or Ca.-dependent K. channels. At a constant stimulatory glucose concentration, APs are clustered in bursts that are interrupted by hyperpolarized interburst phases. Bursting electrical activity induces parallel fluctuations in [Ca.]. and in作者: Minuet 時間: 2025-3-27 13:38
Exercise-Induced Pancreatic Islet Adaptations in Health and Disease,ces β-cell survival is a common outcome in all of the studies. Exercise training-induced alterations on β-cell functions are more controversial. Generally, the studies indicate that in healthy and obese insulin-resistant subjects, exercise decreases nutrient-induced insulin secretion (associated wit作者: 誤傳 時間: 2025-3-27 18:40
,Exocytosis in Islet β-Cells, using the currently available electrophysiological techniques. This chapter provides a concise introduction to the field of optical imaging for those researchers who wish to characterize exocytosis from β-cells in the islets of Langerhans.作者: 類人猿 時間: 2025-3-28 00:18 作者: Mingle 時間: 2025-3-28 05:17
,High-Fat Programming of β-Cell Dysfunction,bolism of the progeny throughout life. This more recently adopted form of developmental programming reflects society in both affluent and developing countries. High-fat programming induces adverse changes in β-cell development and function in neonatal, weanling, and adolescent progeny. These changes作者: gruelling 時間: 2025-3-28 07:45 作者: 大看臺 時間: 2025-3-28 13:58
Haruo Kasai,Hiroyasu Hatakeyama,Mitsuyo Ohno,Noriko Takahashiasserkuppe über die Berge der Rh?n, mit ihr promenieren am Strande Spitzbergens, dort über m?chtige Gletscher hinweg auf die schwarzen scharfen Zinnen steigen, mit ihr auf Meereswellen herumspazieren, dem alten berühmten Moltke um die Nasenkuppe herumklettern, mit ihr auf einem lebenden Fische sitze作者: 剝皮 時間: 2025-3-28 16:16
Blair K. Gage,Rhonda D. Wideman,Timothy J. Kiefferasserkuppe über die Berge der Rh?n, mit ihr promenieren am Strande Spitzbergens, dort über m?chtige Gletscher hinweg auf die schwarzen scharfen Zinnen steigen, mit ihr auf Meereswellen herumspazieren, dem alten berühmten Moltke um die Nasenkuppe herumklettern, mit ihr auf einem lebenden Fische sitze作者: 使迷醉 時間: 2025-3-28 22:49
Marlon E. Cerfasserkuppe über die Berge der Rh?n, mit ihr promenieren am Strande Spitzbergens, dort über m?chtige Gletscher hinweg auf die schwarzen scharfen Zinnen steigen, mit ihr auf Meereswellen herumspazieren, dem alten berühmten Moltke um die Nasenkuppe herumklettern, mit ihr auf einem lebenden Fische sitze作者: 拉開這車床 時間: 2025-3-29 02:13 作者: prediabetes 時間: 2025-3-29 03:38 作者: perimenopause 時間: 2025-3-29 10:51 作者: observatory 時間: 2025-3-29 12:45
Xavier Montet,Smaragda Lamprianou,Laurent Vinet,Paolo Meda,Alfredo Fort作者: Pillory 時間: 2025-3-29 19:35
Colin A. Leech,Richard F. Kopp,Louis H. Philipson,Michael Wm. Roe作者: 彩色 時間: 2025-3-29 22:10
Mauricio Di Fulvio,Peter D. Brown,Lydia Aguilar-Bryan作者: 胡言亂語 時間: 2025-3-30 00:54
Jeongkyung Lee Ph.D.,Mousumi Moulik M.D.,Vijay K. Yechoor M.D.作者: VEST 時間: 2025-3-30 04:58 作者: 高度贊揚 時間: 2025-3-30 08:20 作者: Anguish 時間: 2025-3-30 15:46 作者: 躺下殘殺 時間: 2025-3-30 18:57
Advances in Clinical Islet Isolation,ibute to the further improvements in long-term clinical outcome. This chapter outlines the criteria for selecting appropriate donors for islet isolation and transplantation, describes the processes involved in islet isolation, and discusses the scope for areas of further improvements.作者: Galactogogue 時間: 2025-3-30 23:00 作者: 易碎 時間: 2025-3-31 02:11 作者: harmony 時間: 2025-3-31 07:34
Human Islet Autotransplantation,ion. Consequently, insulin independence is more likely to be preserved in autoislet-transplanted patients than in those patients who received alloislet transplants. Therefore, the setting of islet autotransplantation allows the study of the transplanted islets without interference from medication or immunological variables.作者: follicle 時間: 2025-3-31 10:36
utting Edge Research Great Ideas and Directions for Future IThis book contains critical background information, and recent advances made in essentially all areas of islet research. It is a major reference book, the first of its kind, for islet researchers, and diabetes researchers. Anybody, includin作者: fatuity 時間: 2025-3-31 14:37 作者: 笨拙處理 時間: 2025-3-31 20:47
,Current Approaches and Future Prospects for the Prevention of β-Cell Destruction in Autoimmune Diab chapter, the authors have reviewed recent approaches that are currently being tested in animal models and human T1D patients under the following categories: (i) antigen-based therapy, (ii) antibody-based therapy, (iii) immunomodulating therapy, and (iv) other form of therapies.作者: indecipherable 時間: 2025-3-31 22:45
Anionic Transporters and Channels in Pancreatic Islet Cells, hypothesis, the expression and function of anoctamin 1 in rodent and human pancreatic islet cells, the possible role of bicarbonate-activated soluble adenylyl cyclase, the identity and role of aquaporins in insulin-producing cells, and a proposed role for volume-regulated anion channels in glucagon secretion.作者: BAIT 時間: 2025-4-1 02:48
Chloride Channels and Transporters in Beta-Cell Physiology,he β-cell secretory response. We have therefore concentrated on key concepts, and on what we consider may be the most important players involved in the regulation of [Cl.]. in β-cells, but time will tell.作者: 收養(yǎng) 時間: 2025-4-1 09:05
Electrical, Calcium, and Metabolic Oscillations in Pancreatic Islets,perimental studies that have tested unintuitive predictions of the model and have thereby provided the best evidence to date that oscillations in glycolysis underlie the slow (~15 min) component of electrical, calcium, and metabolic oscillations in mouse islets.作者: 多產(chǎn)魚 時間: 2025-4-1 12:43
Temporal Trends in Water Discharge Characteristics of the Large Peninsular Rivers: Assessing the Rocharge trends for the peninsular rivers were statically calculated. On-parametric Mann-Kendall test and linear regression analysis were applied to identify peninsular rivers with remarkable discharge variations. In the case of large rivers, the change varies between ?79.1% and 29.5%. Large peninsula作者: 敵手 時間: 2025-4-1 18:08 作者: Ondines-curse 時間: 2025-4-1 22:26 作者: indecipherable 時間: 2025-4-1 23:48 作者: hegemony 時間: 2025-4-2 06:35
