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標(biāo)題: Titlebook: Ion Channels; Bernard Fermini,Birgit T. Priest Book 2008 Springer-Verlag Berlin Heidelberg 2008 Biomedicine.Medicinal Chemistry.Molecular [打印本頁]

作者: CHORD    時(shí)間: 2025-3-21 19:05
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作者: 凹室    時(shí)間: 2025-3-21 21:29
Role of Kv7 and Cav3 Ion Channels in Pain, of expressed ion channel proteins. Ion channels,therefore, present excellent molecular targets for designing new therapeutic molecules to manage pain. Inthis review we discuss two classes of channels which are currently of interest to the pharmaceutical communityin this area. The first are Kv7 pota
作者: 樂章    時(shí)間: 2025-3-22 02:33
Potassium Channels: Oncogenic Potential and Therapeutic Target for Cancers,ween the two coordinates developmental morphogenesis,cell homeostasis, and tissue modeling in organisms. Abnormally enhanced proliferation and/or impaired celldeath often cause loss of control of cell growth leading to tumorigenesis or cancer formation. Severalfundamental steps need to be fulfilled
作者: GLIDE    時(shí)間: 2025-3-22 07:48
Pharmacological Rescue of Mutant CFTR Function for the Treatment of Cystic Fibrosis,ansmembrane conductance regulator (CFTR). CFTR is a?PKA-regulatedanion channel localized in the apical membrane of bronchial epithelia where it controls salt and fluid regulationto facilitate bacteria clearance. There are over 1000 disease-causing mutations in the gene encoding CFTRand, depending on
作者: 精密    時(shí)間: 2025-3-22 09:36
On the Process of Finding Novel and Selective Sodium Channel Blockers for the Treatment of Diseasesltage-gated sodium channels are challenging drug targets, andmost of the clinically used drugs were found before their sodium channel blocking mechanism was known. Sodiumchannels are a?family of ten homologous subtypes, and family members are expressed differentially throughoutthe nervous system and
作者: Barrister    時(shí)間: 2025-3-22 14:44
Kv1.5 Potassium Channel Inhibitors for the Treatment and Prevention of Atrial Fibrillation, atrial but not ventricular myocytes. Inhibition of Kv1.5 has been widely recognized as a?potentialtherapeutic strategy for the treatment of atrial fibrillation (AF), a?major clinical concern, especiallyin aging populations. This review centers on recent Kv1.5 drug discovery and development, in the
作者: Tartar    時(shí)間: 2025-3-22 18:37
Denken. Dazu erschlie?t er die fachwissenschaftliche Perspektive des Entrepreneurships, erg?nzt diese um fachdidaktische Konkretisierungen der Entrepreneurship Education und integriert kompetenz- und testtheoretische Grundlagen. Auf dieser Basis entwickelt er ein durch Expert*innen inhaltsvalidierte
作者: 不容置疑    時(shí)間: 2025-3-22 23:06
Zhiguo Wangid Product Developments.Renommierte Experten bieten neueste ?Wenn wir Schlittschuh über dünnes Eis laufen, liegt unser Heil nur in der Schnelligkeit.“ meinte Ralph Waldo Emerson (1803 82), amerikanischer Philosoph und Dichter. Innovationsorientierte Unternehmen müssen in der Lage sein zu beschleunig
作者: Vo2-Max    時(shí)間: 2025-3-23 03:38

作者: 碎石    時(shí)間: 2025-3-23 08:10
Birgit T. Priestid Product Developments.Renommierte Experten bieten neueste ?Wenn wir Schlittschuh über dünnes Eis laufen, liegt unser Heil nur in der Schnelligkeit.“ meinte Ralph Waldo Emerson (1803 82), amerikanischer Philosoph und Dichter. Innovationsorientierte Unternehmen müssen in der Lage sein zu beschleunig
作者: 鴿子    時(shí)間: 2025-3-23 10:28
Armando Lagrutta,Laszlo Kiss,Joseph J. Salataid Product Developments.Renommierte Experten bieten neueste ?Wenn wir Schlittschuh über dünnes Eis laufen, liegt unser Heil nur in der Schnelligkeit.“ meinte Ralph Waldo Emerson (1803 82), amerikanischer Philosoph und Dichter. Innovationsorientierte Unternehmen müssen in der Lage sein zu beschleunig
作者: 有罪    時(shí)間: 2025-3-23 14:33
id Product Developments.Renommierte Experten bieten neueste ?Wenn wir Schlittschuh über dünnes Eis laufen, liegt unser Heil nur in der Schnelligkeit.“ meinte Ralph Waldo Emerson (1803 82), amerikanischer Philosoph und Dichter. Innovationsorientierte Unternehmen müssen in der Lage sein zu beschleunig
作者: 投射    時(shí)間: 2025-3-23 21:56
Bernard Fermini,Birgit T. PriestIn each volume an overview chapter introduces the newcomer to the topic covered.Series covers hot topics of frontier research summarized by reputed scientists in the field.Review series is topic relat
作者: Rheumatologist    時(shí)間: 2025-3-23 22:26

作者: Gyrate    時(shí)間: 2025-3-24 04:16
978-3-642-09855-0Springer-Verlag Berlin Heidelberg 2008
作者: 神圣在玷污    時(shí)間: 2025-3-24 07:45

作者: 葡萄糖    時(shí)間: 2025-3-24 12:23
https://doi.org/10.1007/978-3-540-79729-6Biomedicine; Medicinal Chemistry; Molecular Chemistry; Organic Chemistry; Pharmaceutical Chemistry; Pharm
作者: 解決    時(shí)間: 2025-3-24 18:28
1862-2461 reputed scientists in the field.Review series is topic relat.Ion channels play a vital role in basic physiological functions such as generation of electrical activity in nerves and muscle, control of cardiac excitability, intracellular signaling, hormone secretion, cell proliferation and many other
作者: 緩解    時(shí)間: 2025-3-24 19:35
Book 2008citability, intracellular signaling, hormone secretion, cell proliferation and many other biological processes. Because of their prevalence and the critical role they play in virtually all tissue types and organs, ion channels are also involved in a number of pathophysiological conditions. The aim o
作者: Deject    時(shí)間: 2025-3-24 23:44

作者: 打谷工具    時(shí)間: 2025-3-25 03:44
Recent Advances in Ion Channel Screening Technologies, or mutant ion channel genes usingtraditional ion channel screening technologies. Therefore, several efforts were undertaken to automateand improve the throughput of electrophysiological methods. In this chapter, we will review a?numberof the more standard ion channel screening technologies currentl
作者: Mirage    時(shí)間: 2025-3-25 11:11

作者: 休息    時(shí)間: 2025-3-25 13:09
Pharmacological Rescue of Mutant CFTR Function for the Treatment of Cystic Fibrosis, on their mode of action. The first class is known as CFTRcorrectors because they correct the processing and trafficking of CFTR to increases its cell surface density.The second class is known as CFTR potentiators as they potentiate the amount of anion secretion throughCFTR at the cell surface. In v
作者: 泄露    時(shí)間: 2025-3-25 19:03
On the Process of Finding Novel and Selective Sodium Channel Blockers for the Treatment of Diseaseseally suited for this task, and the recent development of automated electrophysiologyinstrumentation affords medium throughput. Higher capacity assays amenable to studying sodium channel pharmacologyinclude ligand binding, flux, and fluorescent assays.
作者: EXCEL    時(shí)間: 2025-3-25 22:01
Kv1.5 Potassium Channel Inhibitors for the Treatment and Prevention of Atrial Fibrillation,inite proof of concept for Kv1.5 inhibition as an effective antiarrhythmic strategyawaits agents with greater Kv1.5 selectivity and a?more detailed characterization of . .in human atria and the consequence of its inhibition.
作者: 不幸的人    時(shí)間: 2025-3-26 03:40
Book 2008target, the current status in the development of agents to treat the disease, and future prospects and challenges facing each therapeutic area. The reader will receive a critical overview covering the progress made in the rapidly developing and complex field of ion channels and diseases. .
作者: 犬儒主義者    時(shí)間: 2025-3-26 04:18

作者: BACLE    時(shí)間: 2025-3-26 12:12

作者: 小爭吵    時(shí)間: 2025-3-26 15:49
Fredrick Van Goor,Sabine Hadida,Peter Grootenhuisid Prototy ping“ ist die Zielsetzung des von der DFG gef?rderten Sonderforschungs bereichs 374, dessen Ergebnisse in diesem Band beschrieben werden.978-3-540-69880-7Series ISSN 2512-5281 Series E-ISSN 2512-529X
作者: contradict    時(shí)間: 2025-3-26 20:17

作者: 急性    時(shí)間: 2025-3-26 21:17
Armando Lagrutta,Laszlo Kiss,Joseph J. Salataid Prototy ping“ ist die Zielsetzung des von der DFG gef?rderten Sonderforschungs bereichs 374, dessen Ergebnisse in diesem Band beschrieben werden.978-3-540-69880-7Series ISSN 2512-5281 Series E-ISSN 2512-529X
作者: 憤慨點(diǎn)吧    時(shí)間: 2025-3-27 01:59
id Prototy ping“ ist die Zielsetzung des von der DFG gef?rderten Sonderforschungs bereichs 374, dessen Ergebnisse in diesem Band beschrieben werden.978-3-540-69880-7Series ISSN 2512-5281 Series E-ISSN 2512-529X
作者: Lineage    時(shí)間: 2025-3-27 08:53
1862-2461 rospects and challenges facing each therapeutic area. The reader will receive a critical overview covering the progress made in the rapidly developing and complex field of ion channels and diseases. .978-3-642-09855-0978-3-540-79729-6Series ISSN 1862-2461 Series E-ISSN 1862-247X
作者: 疏忽    時(shí)間: 2025-3-27 11:43

作者: Introvert    時(shí)間: 2025-3-27 15:53

作者: 儀式    時(shí)間: 2025-3-27 17:46
Imaging of the Clavicle,and integrity following injury to the sternoclavicular or acromioclavicular joints as well as complex reconstructions. Finally, the procedural use of ultrasound to guide injections of the acromioclavicular and sternoclavicular joints for either diagnostic or therapeutic injections is also practicall
作者: infarct    時(shí)間: 2025-3-27 22:10
Beratungsbranche diskutiert: Erfolgskriterien von PR-Agenturen und Kunden werden ebenso beleuchtet wie das Wissensmanagement in PR-Agenturen, Typen von PR-Dienstleistern in der Politik, Genderaspekte in der PR-Beratung sowie die R978-3-531-16955-2978-3-531-91916-4
作者: 最高點(diǎn)    時(shí)間: 2025-3-28 05:08
978-3-319-87564-4The Editor(s) (if applicable) and The Author(s) 2017
作者: 天賦    時(shí)間: 2025-3-28 07:47

作者: grenade    時(shí)間: 2025-3-28 12:36
Screening for Incidental (Stage T1) Prostate Cancer,d prostate cancer screening studies in particular. Finally, we conclude with some comments on the natural history of stage T1 prostate cancer which suggest that in addition to tests with reasonable diagnostic predictive value we also need tests to determine the prognosis of a histologically diagnosed prostate cancer.




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