作者: BUOY 時間: 2025-3-21 23:07
Evan Luarddleman .., 1973). In microsomes prepared from the normal kidney, the medulla is the primary site of arachidonic acid metabolism; much less PG produetion occurs in the cortex (Larsson and Anggard, 1974). Unilateral Ureter obstruction (hydronephrosis) for several days results in a marked facilitation 作者: 諂媚于性 時間: 2025-3-22 04:24 作者: 彎腰 時間: 2025-3-22 07:58 作者: Morbid 時間: 2025-3-22 10:43
Evan Luardor of dopaminergic activity and mediates dopamine actions on motivation and reward. We have identified a single nucleotide polymorphism in the DRD2 gene (rs2734836) that reduces the binding of the transcriptional repressor Freud-1/CC2D1A and in turn alters expression of the dopamine D2 receptor (Rog作者: 假 時間: 2025-3-22 16:39
Evan Luardassical second messenger signaling pathways. The ., or GPCR-induced activation of receptor tyrosine kinases (RTKs), presents an avenue for GPCRs to affect signaling pathways that have previously been attributed to growth factors and opens the door for modulation of RTK activity with small-molecule G作者: 鞭子 時間: 2025-3-22 19:55 作者: Perigee 時間: 2025-3-22 22:54
Evan Luardassical second messenger signaling pathways. The ., or GPCR-induced activation of receptor tyrosine kinases (RTKs), presents an avenue for GPCRs to affect signaling pathways that have previously been attributed to growth factors and opens the door for modulation of RTK activity with small-molecule G作者: Aggressive 時間: 2025-3-23 04:09 作者: 袖章 時間: 2025-3-23 06:13 作者: visceral-fat 時間: 2025-3-23 10:02 作者: 巧辦法 時間: 2025-3-23 14:23 作者: 可以任性 時間: 2025-3-23 19:35 作者: CARK 時間: 2025-3-23 23:42
Evan Luardonotropic and metabotropic receptors abundantly expressed along the whole extent of the neuraxis. Abnormal regulation of glutamatergic transmission is, therefore, a key factor that underlies the appearance and progression of many neurodegenerative and psychiatric diseases. Unfortunately, the success作者: 卜聞 時間: 2025-3-24 03:32
Evan Luard known since 1978 to be divided between two families differing in biochemical and pharmacological properties (.). Although the G protein and second messenger systems affected by dopamine receptors in vivo have not been clearly established, in vitro D1-family receptors (D1 and D5) couple to Gs stimul作者: Heart-Rate 時間: 2025-3-24 09:42
Evan Luard amines and acids, neuropeptides, and neurosteroids in corticomesolimbic circuits (.). Beginning with invertebrates, the critical role of serotonin (5-HT) for aggression-inhibiting mechanisms has emerged, and it is important to understand how other transmitters, such as DA and glutamate, interact wi作者: Anthem 時間: 2025-3-24 12:01 作者: Substance-Abuse 時間: 2025-3-24 15:46
Evan Luardy both in the nucleus accumbens and prefrontal cortex during rapid-eye-movement (REM) sleep; this DAergic activity has been involved in the generation of dreams. The melanin-concentrating hormone (MCH) is a peptide with neuromodulatory functions synthesized by neurons located in the postero-lateral 作者: Horizon 時間: 2025-3-24 22:24 作者: 時間等 時間: 2025-3-25 00:47 作者: GONG 時間: 2025-3-25 04:47 作者: mortuary 時間: 2025-3-25 09:47
Space,unction—the administration of those areas of no man’s land in which no effective local power exists. There are three main areas of this kind: space, the sea-bed, and the Antarctic. In each of these, some form of international control has begun to evolve to prevent national competition leading to a s作者: mitten 時間: 2025-3-25 12:46 作者: 沖突 時間: 2025-3-25 18:29 作者: Badger 時間: 2025-3-25 20:38 作者: Classify 時間: 2025-3-26 04:09
Social Policy,lt to be international as well as national. Over social evils such as drugs and prostitution, over the care of the internationally destitute, such as refugees, over the establishment of educational services to combat ignorance and illiteracy, even over such questions as housing, crime and punishment作者: 單片眼鏡 時間: 2025-3-26 07:31
Trade,national governments gradually asserted increasing control over economic relations among their citizens-first to make trade freer, to break down the restrictive practices of the guilds and to remove local taxes and local octrois imposed by individual towns and localities, and later to make trade fai作者: ellagic-acid 時間: 2025-3-26 12:26 作者: 哄騙 時間: 2025-3-26 15:59
The Techniques of International Government, governments. The most obvious difference between international and national administration is that international organizations do not dispose of the ultimate sanction of coercive power to secure compliance. International organizations have considerable ., but no power. National governments may be p作者: bleach 時間: 2025-3-26 18:58 作者: Chronological 時間: 2025-3-27 00:04 作者: OATH 時間: 2025-3-27 02:06 作者: Latency 時間: 2025-3-27 06:59
Trade,rer, to regulate the conditions of commerce, to lay down company law, to prevent monopoly and restrictive practices, and to protect the consumer-so international government has increasingly had to intervene for similar purposes: first to make trade freer among states, and later to make it fairer between them.作者: Solace 時間: 2025-3-27 10:03 作者: cumber 時間: 2025-3-27 15:07
the presence of dopaminergic neurons in the cord together with speculation about their possible physiological role (Commissiong .., 1978; Gentleman ., 1981; Commissiong and Neff, 1979). What percentage of dopamine should be found in a nerve or tissue to raise suspicion that dopaminergic neurons are作者: AMOR 時間: 2025-3-27 20:03
Evan Luardble in normal or contralateral unobstrueted rabbit kidneys (CLK) (Morrison ., 1977, 1978). Measurement of prostaglandins by radioimmunoassay demonstrated that PGE. , 6-keto-PGF., and TxB. levels are increased in the venous effluent of the hydronephrotic kidney in both the basal and hormone-stimulate作者: mosque 時間: 2025-3-27 23:27 作者: encomiast 時間: 2025-3-28 05:15
Evan Luardlities. This volume, the first in a series of publications arising from the annual Smith Kline and French Research Symposium on New Horizons in Therapeutics, provides a comprehensive survey of current research on peripheral dopamine receptors and the physiologic and therapeutic con- sequences of sti作者: ticlopidine 時間: 2025-3-28 10:05 作者: Progesterone 時間: 2025-3-28 10:34 作者: Compass 時間: 2025-3-28 16:22 作者: ostracize 時間: 2025-3-28 21:27
Evan Luardcell surface. Although the discovery of RTK transactivation is relatively recent, a growing body of research has identified these pathways in several cell line, primary cell, and in vivo systems. These studies have characterized the time course and magnitude of RTK transactivation and have identifie作者: 傳染 時間: 2025-3-29 00:33
Evan Luardize that differences in DNA methylation of the DRD2 promoter may correlate with altered expression of the receptor in adults, and predispose to schizophrenia. In this chapter, we review methods for both genotype analysis of key polymorphisms of the DRD2 gene (rs2734836 and the Taq1A variant rs180049作者: extrovert 時間: 2025-3-29 06:34 作者: Inexorable 時間: 2025-3-29 09:32
Evan Luardt the exact opposite of those of depression. In major depressive disorders, there is a high risk not only for suicide but also for life-threatening effects on multiple organ systems, so it is considered that the mortality risk engendered by major depression is similar to that of the more severe card作者: 欲望小妹 時間: 2025-3-29 12:43 作者: 斜谷 時間: 2025-3-29 17:59
Evan Luard motor behavior, depression, anxiety, drug abuse, epilepsy, and others. Some ligands of ionotropic receptors have already been introduced to clinical practice (e.g., amantadine, memantine, .-cycloserine), whereas mGluRs may be considered as an emerging target for the treatment of several diseases (e作者: grandiose 時間: 2025-3-29 20:54 作者: NUL 時間: 2025-3-30 02:54
Evan Luardne may mediate a complex array of neural signaling pathways in vivo. Dopamine systems are believed to exert functional effects through these second-messenger signaling pathways via modulation of the activity of more rapidly acting ionotropic glutamatergic, GABAergic, and nicotinic cholinergic neuron作者: 責(zé)任 時間: 2025-3-30 06:48
Evan Luarddividuals and victims of violence document the magnitude and urgency of the problem and the need for increasing the understanding the neurobiological basis of these adaptive and pathological behaviors. Although most acts of violence are committed by individuals who are not in mental health settings,作者: enlist 時間: 2025-3-30 10:08
Evan Luardinvolved combined with the multifarious effects glutamate could mediate via pre- and postsynaptic interactions with various receptor subtypes, have led to important controversies regarding the exact role glutamate plays in psychiatric diseases. However, substantial progress has been made over the pa作者: 門閂 時間: 2025-3-30 14:35 作者: 微枝末節(jié) 時間: 2025-3-30 20:16
Evan Luarde in greater than precursor amounts seemed to be limited to ruminants, and in ruminant tissues it correlated strongly to the occurrence of mast cells (Bertler et al. 1959). What function dopamine might serve in the mast cells of ruminants remained completely unknown. Speculations about an independen作者: 消極詞匯 時間: 2025-3-30 23:58
Evan Luard, efficient therapeutic protocols for the treatment of this disease utilize drugs that modulate the function of the dopaminergic system. Consequently, the principal aims of the study of the dopaminergic system are to identify and characterize the function of each of its components, and to understand作者: 有法律效應(yīng) 時間: 2025-3-31 01:25 作者: Vo2-Max 時間: 2025-3-31 05:08
Palgrave Macmillan, a division of Macmillan Publishers Limited 1977作者: Altitude 時間: 2025-3-31 10:20
Overview: 978-1-349-03103-0作者: 去掉 時間: 2025-3-31 14:18 作者: gusher 時間: 2025-3-31 19:40 作者: 偽證 時間: 2025-4-1 01:00
Meteorology,orld and growing traffic have demanded ever more detailed international control. And we saw how access to hitherto undiscovered regions, belonging to no nation, has made necessary increasing regulation on an international basis there. We now turn to another area where the same process of shrinkage has led to the same result.作者: conjunctivitis 時間: 2025-4-1 04:20 作者: Ligneous 時間: 2025-4-1 09:19 作者: 凈禮 時間: 2025-4-1 10:23 作者: fatuity 時間: 2025-4-1 17:36
