標題: Titlebook: Insulin, Insulin-like Growth Factors, and Their Receptors in the Central Nervous System; Mohan K. Raizada,M. Ian Phillips,Derek LeRoith Bo [打印本頁] 作者: 相反 時間: 2025-3-21 19:09
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作者: Mercantile 時間: 2025-3-21 21:20 作者: Costume 時間: 2025-3-22 04:12
Role of Protein Phosphorylation in Growth Factor Signal Transductiongical conditions including diabetes. In this paper, which consists primarily of a review of work carried out here and elsewhere, a role for protein phosphorylation in the mediation of many of the metabolic responses of cells to growth factors is examined.作者: Texture 時間: 2025-3-22 06:49
Glucose Transporters: Overview and Implications for the Brainrthermore, we will examine the role of the glucose transport effector system in pathophysiologic insulin-resistant states and modifications which prevent the insulin response in insulin insensitive tissues such as liver and brain.作者: 易受刺激 時間: 2025-3-22 09:15 作者: 桶去微染 時間: 2025-3-22 15:28 作者: 法官 時間: 2025-3-22 17:29 作者: 美學 時間: 2025-3-22 23:50 作者: 大范圍流行 時間: 2025-3-23 05:01
Structural Evidence for a Subtype of Insulin Receptor in the Central Nervous Systemin the CNS. Consistent with this notion is the report that Zucker rats carrying the fa gene have fewer brain insulin receptors.. Furthermore, insulin has been shown to directly alter the firing rate of glucose-sensitive neurons in the ventromedial and lateral hypothalamus..作者: 排他 時間: 2025-3-23 06:34 作者: 關心 時間: 2025-3-23 12:49 作者: GULF 時間: 2025-3-23 17:50
Evolution of Insulin and Insulin Receptors a related molecule can be produced by tissues other than a pancreas. In the second part, we will describe studies on the phylogenetic conservation of the brain insulin receptor. Finally, we discuss the phylogenetic and developmental conservation of the structurally unique brain insulin receptor.作者: Postmenopause 時間: 2025-3-23 21:08 作者: LAP 時間: 2025-3-23 22:40 作者: liposuction 時間: 2025-3-24 06:11 作者: 心神不寧 時間: 2025-3-24 08:15
Michel Bernier,Susan C. Frost,Don M. Laird,Ronald A. Kohanski,M. Daniel Lane16 presidential election, the legacy of Obama‘s second term .In this state-of-the-art textbook, a distinguished team of established experts and rising scholars discuss the legacy of the Obama years and the impact of the unexpected Trump presidential victory of 2016. Carrying on the tradition set by 作者: 盡管 時間: 2025-3-24 11:13
S. L. Pelech,D. A. Tinker,C. P. Chan,E. G. Krebs16 presidential election, the legacy of Obama‘s second term .In this state-of-the-art textbook, a distinguished team of established experts and rising scholars discuss the legacy of the Obama years and the impact of the unexpected Trump presidential victory of 2016. Carrying on the tradition set by 作者: 在駕駛 時間: 2025-3-24 15:39 作者: insurgent 時間: 2025-3-24 20:50
Robert V. Farese,Denise R. Cooper16 presidential election, the legacy of Obama‘s second term .In this state-of-the-art textbook, a distinguished team of established experts and rising scholars discuss the legacy of the Obama years and the impact of the unexpected Trump presidential victory of 2016. Carrying on the tradition set by 作者: surmount 時間: 2025-3-24 23:40 作者: 帳單 時間: 2025-3-25 04:20
Shoou-Lih Wang,Mohan K. Raizada,Kathleen T. Shiverick16 presidential election, the legacy of Obama‘s second term .In this state-of-the-art textbook, a distinguished team of established experts and rising scholars discuss the legacy of the Obama years and the impact of the unexpected Trump presidential victory of 2016. Carrying on the tradition set by 作者: daredevil 時間: 2025-3-25 10:28 作者: 一回合 時間: 2025-3-25 13:53 作者: 初學者 時間: 2025-3-25 18:55 作者: 厭煩 時間: 2025-3-25 22:53
G. Colin Budd,Ben Pansky16 presidential election, the legacy of Obama‘s second term .In this state-of-the-art textbook, a distinguished team of established experts and rising scholars discuss the legacy of the Obama years and the impact of the unexpected Trump presidential victory of 2016. Carrying on the tradition set by 作者: 入會 時間: 2025-3-26 00:53 作者: Accede 時間: 2025-3-26 04:47
M. Ian Phillipsre electoral coalitions of interests and groups appealing to different sections of the US electorate. As the chapter explains, those coalitions have not been static. Rather they have adapted to changes in the wider society. Two major periods of transformation in the composition of the parties have s作者: dandruff 時間: 2025-3-26 11:17 作者: 發(fā)電機 時間: 2025-3-26 14:55
Mohan K. Raizada,Frederick T. Boyd,Derrel W. Clarke,Derek Le Roithc established a new menu of policy possibilities for the Biden administration. It pays particular attention to the ways that Trump broke with the traditional Republican social policy agenda and where he embraced its longstanding agenda of limiting public social provision. The chapter examines the ad作者: 平 時間: 2025-3-26 19:45 作者: 斗志 時間: 2025-3-26 21:56
Elaine M. Richards,Mohan K. Raizada,Colin Sumnersber of effective antimicrobial agents, a change in the pattern of many infections has occurred from acquisition outside of the hospital to acquisition within the hospital [1]. Bacterial infections of the respiratory tract have been reported to occur in 0.5 to 5.0% of hospitalized patients [2]. In a 作者: 異端 時間: 2025-3-27 01:25 作者: 夜晚 時間: 2025-3-27 07:54 作者: Instantaneous 時間: 2025-3-27 09:36 作者: 尖叫 時間: 2025-3-27 16:45
Insulin-Activated Phosphorylation on Tyrosine of a 15 Kilodalton Cytosolic Protein in 3T3-L1 Adipocy a signal, which when transmitted across the plasma membrane, is propagated and distributed to pleitropic control points of cellular metabolism. Modulation by insulin of flux through these controlled reactions is responsible for regulation of the major energy storage pathways in many cell types. In 作者: 火海 時間: 2025-3-27 21:32 作者: Barter 時間: 2025-3-27 22:45 作者: musicologist 時間: 2025-3-28 04:16 作者: Metastasis 時間: 2025-3-28 08:55 作者: Parley 時間: 2025-3-28 13:12
Alteration of Insulin Receptor Binding and Protein Kinase Activity in Rat Liver and Placenta by ?-Naes is characterized by an increase in binding activity with gestational age.. Human placenta is a rich source of insulin receptor which has been extensively characterized for its physico-chemical and protein kinase properties.. Exposure to polyaromatic compounds during pregnancy has been associated 作者: 會議 時間: 2025-3-28 16:01
Evolution of Insulin and Insulin Receptorsay be extrapancreatic sources of insulin and that insulin may act on tissues other than its classic target tissues. Of specific interest to us has been the suggestion that nervous tissue may be an extrapancreatic source of insulin synthesis and, furthermore, that nervous tissue may be a specific tar作者: 出汗 時間: 2025-3-28 22:03
Evidence for Central Nervous System Insulin Synthesis, two basic questions have remained unanswered. The first is the source of this insulin within the CNS, whether locally produced or of pancreatic origin. Second is the function of insulin within the CNS. Does insulin have similar effects. centrally to those outside the CNS or does insulin have uniqu作者: 打火石 時間: 2025-3-29 01:03
Localization of Insulin to Neuronal Cellscribed in the central nervous system., the exact origin of the peptide remains unclear. A local (i.e. central nervous system) origin for the peptide has been suggested by some groups of investigators., while others contend that insulin enters the brain from the blood vascular system .. For example, 作者: Neutral-Spine 時間: 2025-3-29 06:21
Synthesis of Insulin or a Similar Peptide in the Pituitary Gland and in Retinal Muller Cellsoith, et al., 1980, 1981, 1983; Falkner, et al., 1975; Meneses and Oritz, 1975; Duve and Thorpe, 1979; Yuri, et al., 1980)., Similar reports have appeared claiming localization and possible synthesis of insulin in the extrapancreatic tissues of vertebrates (Hendricks, et al.,1983). Proposed extrapan作者: Vertical 時間: 2025-3-29 08:11
Insulin in the Central Nervous System: A Regulator of Appetite and Body Weightquences of these actions at the level of the organism have not been defined. In this chapter we advance the hypothesis that insulin may act as a regulator of body weight. In 1979, Woods and Porte suggested that insulin levels in the cerebrospinal fluid (CSF) may act as an indicator of body adiposity作者: elastic 時間: 2025-3-29 15:08
Insulin in the Brain: A Feedback Loop Involving Brain Insulin and Circumventricular Organsd not influence the brain. The independence of the central nervous system (CNS) from peripheral insulin has always had a certain teleological logic to it. The brain, being so important physiologically, must be preserved from having to require insulin to control its glucose metabolism. Since insulin 作者: 特征 時間: 2025-3-29 17:40
Structural Evidence for a Subtype of Insulin Receptor in the Central Nervous Systemcal role of insulin in the central nervous system (CNS). One area of CNS physiology affected by insulin is the regulation of feeding behavior and body weight. Chronic intracerebral ventricular infusion of insulin reduces food intake and body weight., suggesting that insulin acts as a satiety factor 作者: moribund 時間: 2025-3-29 21:05
Physiologically Unique Insulin Receptors on Neuronal Cellsnal insulin receptors. Kinetic characteristics of .I-insulin binding to neuronal cells were similar to those for glial and peripheral cells although the a and . subunits of the neuronal receptor were significantly smaller in size. Insulin inhibited [.H]norepinephrine uptake and stimulated [.H]-serot作者: Shuttle 時間: 2025-3-30 03:24
Insulin Receptors in Brain Development see Hendricks et al., 1983). Since then, insulin or insulin-like material has been detected in numerous species, both vertebrate and invertebrate, as well as in bacteria and fungi (LeRoith et al., 1980; LeRoith et al., 1981). Accordingly, this has prompted the search in these tissues and cells for 作者: 羊齒 時間: 2025-3-30 06:37 作者: 高貴領導 時間: 2025-3-30 10:51 作者: BOGUS 時間: 2025-3-30 14:42
Insulin-Like Growth Factor Receptors in the Braincreatic islets, for example, enters the brain from the periphery and influences the physiology of the CNS (review by Baskin et al., 1987). The recent appreciation that insulin-like growth factors (IGF’s), peptides with insulin-like structure and biological activity, are also present in the CNS has s作者: Acetaldehyde 時間: 2025-3-30 17:27 作者: NORM 時間: 2025-3-31 00:12 作者: Defraud 時間: 2025-3-31 04:37
Evidence for Central Nervous System Insulin Synthesis, two basic questions have remained unanswered. The first is the source of this insulin within the CNS, whether locally produced or of pancreatic origin. Second is the function of insulin within the CNS. Does insulin have similar effects. centrally to those outside the CNS or does insulin have unique functions in the CNS?作者: interrogate 時間: 2025-3-31 07:05 作者: 曲解 時間: 2025-3-31 11:51
978-1-4684-5382-9Plenum Press, New York 1987作者: REP 時間: 2025-3-31 14:22
Insulin, Insulin-like Growth Factors, and Their Receptors in the Central Nervous System作者: 表臉 時間: 2025-3-31 18:23 作者: 噴油井 時間: 2025-4-1 00:44
Book 1987 not only produced by neural tissues but also exert profound physiological and biochemical effects on these tissues. The area of investigation of CNS insulin and IGF has been expanding rapidly and the availability of this book complete with up-to-date reviews on the subject by leaders in the field a作者: caldron 時間: 2025-4-1 03:56
(IGF) are not only produced by neural tissues but also exert profound physiological and biochemical effects on these tissues. The area of investigation of CNS insulin and IGF has been expanding rapidly and the availability of this book complete with up-to-date reviews on the subject by leaders in the field a978-1-4684-5382-9978-1-4684-5380-5作者: Ophthalmoscope 時間: 2025-4-1 07:17
The Role of Phospholipid Metabolism in Insulin Actionhatidylcholine (PC),. phosphatidylinositol (PI) or a PI-glucosamine complex (PI-glycan).. While it is clear that cell surface receptors are coupled to the PIP. phospholipase C through GTP-binding proteins (which may or may not be inhibited by pertussis toxin), little is known about the mechanisms wh作者: indignant 時間: 2025-4-1 10:54
Alteration of Insulin Receptor Binding and Protein Kinase Activity in Rat Liver and Placenta by ?-Nadecrease in EGF receptor protein kinase activity in the placenta.. TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) administered to newborn mice decreased EGF binding to liver plasma membranes, increased membrane protein kinase activities and elicited symptoms characteristic of excess EGF.. At present, li
