標題: Titlebook: Insulin Action; Ashok K. Srivastava,Barry I. Posner Book 1998 Springer Science+Business Media Dordrecht 1998 ATP.Glycogen.protein.receptor [打印本頁] 作者: Hallucination 時間: 2025-3-21 16:17
書目名稱Insulin Action影響因子(影響力)
書目名稱Insulin Action影響因子(影響力)學科排名
書目名稱Insulin Action網(wǎng)絡(luò)公開度
書目名稱Insulin Action網(wǎng)絡(luò)公開度學科排名
書目名稱Insulin Action被引頻次
書目名稱Insulin Action被引頻次學科排名
書目名稱Insulin Action年度引用
書目名稱Insulin Action年度引用學科排名
書目名稱Insulin Action讀者反饋
書目名稱Insulin Action讀者反饋學科排名
作者: 不持續(xù)就爆 時間: 2025-3-21 22:18
Developments in Molecular and Cellular Biochemistryhttp://image.papertrans.cn/i/image/468176.jpg作者: 冷淡一切 時間: 2025-3-22 02:17 作者: 不來 時間: 2025-3-22 04:55 作者: Pantry 時間: 2025-3-22 12:36
Morris F. Whitehe developing fetus is particularly vulnerable to adverse influences in the environment. . Studies of malformations at birth remained largely in the hands of paediatricians who, for instance, quickly established the con- nection between rubella infection in early pregnancy and the birth of severely 作者: Cursory 時間: 2025-3-22 15:30
Wataru Ogawa,Takashi Matozaki,Masato Kasugaigins back as far as the early 1960s. Originally behavioural teratology grew out of a more general interest in ‘prenatal determinants of behaviour’, the title of Joffe’s 1969 summarisation and critique of the early research in this area. The real impetus, however, that pressed behavioural teratology作者: ABOUT 時間: 2025-3-22 19:22 作者: Lethargic 時間: 2025-3-22 21:24
Joseph Avruchat birth have been described across many generations but the root causes of these events have been enigmatic and difficult to understand. Many factors may contribute to the lack of mechanistic understanding, but the miniscule size, inaccessibility, and the consequences of ethical concerns contribute作者: micronized 時間: 2025-3-23 01:49
Louis Ragolia,Najma Begum due to their anatomical inaccessibility, paucity of tissue, and other factors that make human studies unethical. Many acute and chronic developmental anomalies can trace their origins to postimplantation phases of gestation, where the organs are first being established and growth and differentiatio作者: GRIN 時間: 2025-3-23 05:48
Gianni M. Di Guglielmo,Paul G. Drake,Patricia C. Baass,Fran?ois Authier,Barry I. Posner,John J.M. Beditional accounts of the internal representation of words and the empirical justification of these accounts are examined in detail. Central to traditional theory development have been ideas concerning the manner in which knowledge about words is represented, with many theorists positing many differe作者: agglomerate 時間: 2025-3-23 10:10 作者: overbearing 時間: 2025-3-23 15:41
Feng Liu,Richard A. Rothditional accounts of the internal representation of words and the empirical justification of these accounts are examined in detail. Central to traditional theory development have been ideas concerning the manner in which knowledge about words is represented, with many theorists positing many differe作者: NUL 時間: 2025-3-23 22:01
Paul G. Drake,Barry I. Posnertests of phonological processing given in adulthood but not on tests on memory, attention, or visual perceptual skill. This suggest that phonological processing problems describe a core language deficit of reading disability. This paper examines the test score profiles of subjects categorized by the作者: predict 時間: 2025-3-23 22:45 作者: 眉毛 時間: 2025-3-24 05:16
John C.H. Byon,Anasua B. Kusari,Jyotirmoy Kusaries that takes place during pregnancy coupled together with the variety in the responses of the cytochrome P450 enzymes in terms of induction and inhibition as well as the presence of polymorphic forms which may be present and the influence of the drug transporters make predicting the pharmacokinetic作者: creditor 時間: 2025-3-24 09:40 作者: Patrimony 時間: 2025-3-24 13:05 作者: prostatitis 時間: 2025-3-24 17:22
Ashok K. Srivastava,Sanjay K. Pandeyystems; however, its application to the inner ear is especially challenging. Access to the membranous cochlea is hampered by the bony labyrinth, and the membranous labyrinth itself offers its own technical challenges due to tissue sparsity and difficulty in dissociating and isolating individual cell作者: 壓倒 時間: 2025-3-24 19:51
Maureen J. Charron,Ellen B. Katzr, where they are required for hearing and balance, and in the lateral line, where they detect fluid flow. In mammals, hair cell epithelia are embedded within a bony labyrinth in the skull, which makes access challenging for in vivo studies. In larval zebrafish, however, both inner ear and lateral l作者: Predigest 時間: 2025-3-24 23:12 作者: Decrepit 時間: 2025-3-25 03:23
Betty Lamothe,Bertrand Duvillié,Nathalie Cordonnier,Anne Baudry,Susan Saint-Just,Danielle Bucchini,Jystems; however, its application to the inner ear is especially challenging. Access to the membranous cochlea is hampered by the bony labyrinth, and the membranous labyrinth itself offers its own technical challenges due to tissue sparsity and difficulty in dissociating and isolating individual cell作者: COM 時間: 2025-3-25 07:59
Pascal Peraldi,Bruce Spiegelmanogies, and in reconstructing normal hearing. Auditory peripheral properties cannot be investigated in humans at the level of detail possible in experimental animals and is therefore largely modeled on detailed knowledge obtained from such animals. However, the auditory periphery shows significant di作者: Confidential 時間: 2025-3-25 12:46 作者: 厚顏無恥 時間: 2025-3-25 19:31
The IRS-signalling system: A network of docking proteins that mediate insulin action,factors and cytokines, including insulin. Insulin action is initiated through the insulin receptor, a transmembrane glycoprotein with intrinsic protein tyrosine kinase activity. The tyrosine kinase mediates the insulin response through tyrosine phosphorylation of various cellular substrates, in part作者: SHOCK 時間: 2025-3-25 21:53
Role of binding proteins to IRS-1 in insulin signalling,nases. The activated insulin receptor phosphorylates the intracellular substrate IRS-1, which then binds various signalling molecules that contain SRC homology 2 domains, thereby propagating the insulin signal. Among these IRS-1-binding proteins, the Grb2-Sos complex and the protein tyrosine Phospha作者: incubus 時間: 2025-3-26 00:57
Insulin regulation of the Ras activation/inactivation cycle,ic responses are mediated by signals through the small molecular weight guanine nucleotide binding protein, Ras. In the last decade, great progress has been made in understanding the molecular mechanisms which regulate the insulin mediated conversion of Ras from its inactive, GDP-bound state, to the作者: Ambiguous 時間: 2025-3-26 05:12
Insulin signal transduction through protein kinase cascades,gnalling intermediates, and their status as participants in insulin regulation of energy metabolism. Best characterized is the Ras-MAPK pathway, whose input is crucial to cell fate decisions, but relatively dispensable in metabolic regulation. By contrast the effectors downstream of PI-3 kinase, alt作者: VEIL 時間: 2025-3-26 09:44 作者: Esophagitis 時間: 2025-3-26 16:32
Insulin receptor internalization and signalling,tissues. Insulin binding to its cell surface receptor is rapidly followed by internalization of insulin-IRK complexes into the endosomal apparatus (EN) of the cell. Internalization of insulin into target organs, especially liver, is implicated in effecting insulin clearance from the circulation. Int作者: nocturia 時間: 2025-3-26 19:07
Spatial determinants of specificity in insulin action, remains largely unknown. This review focuses on the role compartmentalization plays in insulin action, both in signal initiation and in signal reception. Two examples are discussed: (1) a novel signalling pathway leading to the phosphorylation of the caveolar coat protein caveolin, and (2) a recent作者: 冰雹 時間: 2025-3-27 00:18 作者: 和諧 時間: 2025-3-27 02:45 作者: Atrium 時間: 2025-3-27 05:52
Regulation of the insulin signalling pathway by cellular protein-tyrosine phosphatases,lar studies, the transmembrane, receptor-type PTPase LAR and the intracellular, non-receptor enzyme PTP1B have been shown to have a direct impact on insulin action in intact cell models. Since insulin signalling can be enhanced by reducing the abundance or activity of specific PTPases, pharmaceutica作者: 斜 時間: 2025-3-27 11:21 作者: 錯誤 時間: 2025-3-27 15:16
Multifunctional actions of vanadium compounds on insulin signaling pathways: Evidence for preferentanism of insulin action as well as the means to overcome the biochemical defects responsible for the resistance. Vanadium compounds have been discovered to mimic many of the metabolic actions of insulin both . and . and improve glycemic control in human subjects with diabetes mellitus. Apart from it作者: Matrimony 時間: 2025-3-27 20:28 作者: 結(jié)果 時間: 2025-3-28 00:10 作者: 規(guī)范就好 時間: 2025-3-28 04:19
Metabolic and therapeutic lessons from genetic manipulation of GLUT4,e homeostasis. Three mouse models are discussed including MLC-GLUT4 mice which overexpress GLUT4 specifically in skeletal muscle, GLUT4 null mice which express no GLUT4, and the MLC-GLUT4 null mice which express GLUT4 only in skeletal muscle. Overexpressing GLUT4 specifically in the skeletal muscle 作者: 尊嚴 時間: 2025-3-28 09:59
Insulin action in skeletal muscle from patients with NIDDM,pheral glucose uptake in NIDDM patients can be localized to defects in insulin action on glucose transport in skeletal muscle. Following short term . exposure to both submaximal and maximal concentrations of insulin, 3-O-methylglucose transport rates are 40–50% lower in isolated skeletal muscle stri作者: 美學 時間: 2025-3-28 12:34
,Genetic manipulation of insulin action and β-cell function in mice,by manipulating insulin action or pancreatic β-cell function in the mouse. The availability of such mutant mice will allow in the future to develop animal models in which the pathophysiologies resulting from polygenic defects might be reconstituted and studied in detail. Such animal models hopefully作者: 狗舍 時間: 2025-3-28 16:58
,TNF-α and insulin resistance: Summary and future prospects, is defined as a smaller than normal response to a certain dose of insulin, and contributes to several pathological problems of obese patients such as hyperlipidemia, arteriosclerosis and hypertension. Several pieces of evidence indicate that the cytokine tumor necrosis factor a (TNF-α) is an import作者: membrane 時間: 2025-3-28 20:53 作者: 極力證明 時間: 2025-3-29 02:25
ts (Homans, 1961). Other rules include equality (i.e., all persons should be rewarded equally, irrespective of their contribution or costs) and the rule of need (i.e., resources should be divided according to needs) (Walster, Berscheid & Walster, 1973). In a review study Hook and Cook (1979) investi作者: Corroborate 時間: 2025-3-29 03:05
Morris F. Whiteat chemotherapeutic agents could cause damage to the developing organism, but the absence of any known examples of drug-induced birth defects had produced an air of complacency which was reinforced by the lack of any specific regulatory requirements for safety evaluation in this area. The magnitude of the tha978-1-4615-9792-6978-1-4615-9790-2作者: 激怒某人 時間: 2025-3-29 10:47 作者: 尋找 時間: 2025-3-29 12:41
Brian P. Ceresa,Jeffrey E. Pessinve, targeting the redox-sensitive residues making the protein larger. Nonreducing SDS-PAGE is performed to separate reduced (labeled) and oxidized (unlabeled) Trx based on their size. Band densitometries can be measured and used in the Nernst equation to calculate redox potentials. These approaches 作者: Custodian 時間: 2025-3-29 15:50
Joseph Avruchncluding those from cancer research, stem cell biology, and developmental biology. New methods created and adapted for studies in developmental toxicology have taken on greater importance as gestational lesions can now be shown to have developmental and health consequences across the entire lifespan作者: 睨視 時間: 2025-3-29 21:35 作者: thwart 時間: 2025-3-30 00:06 作者: Accessible 時間: 2025-3-30 08:00
Cynthia Corley Mastick,Matthew J. Brady,John A. Printen,Vered Ribon,Alan R. Saltielin discourse context. However, for the single word substitution errors, with the exception of homonyms, there were no categories we found for these normals that have not been reported in brain-damaged patients. The data pattern suggests that normal adults employ an interactive approach in the task o作者: Exclude 時間: 2025-3-30 09:53 作者: epidermis 時間: 2025-3-30 16:00
Paul G. Drake,Barry I. Posnerntly impaired on many tests (including rapid naming with or without alternation of stimuli), perform no better than impaired readers on reading and manipulating non-words in spite of better reading achievement. Thus, it would appear that a better adult outcome is related to rapid, perhaps automatize作者: indubitable 時間: 2025-3-30 16:34 作者: 小淡水魚 時間: 2025-3-30 22:06
John C.H. Byon,Anasua B. Kusari,Jyotirmoy Kusarilux transporters such as Pgp, BCRP, and MRP3 and uptake transporters OCT3 and OCTN1 in pregnancy and in the fetus with prescribed medications this information will need to be used in the evaluation. Therefore, for drugs with a narrow therapeutic window or those with marked pharmacologic or toxicolog作者: Delude 時間: 2025-3-31 03:22
I. George Fantus,Evangelia Tsianilux transporters such as Pgp, BCRP, and MRP3 and uptake transporters OCT3 and OCTN1 in pregnancy and in the fetus with prescribed medications this information will need to be used in the evaluation. Therefore, for drugs with a narrow therapeutic window or those with marked pharmacologic or toxicolog作者: 終端 時間: 2025-3-31 05:43
Gary Sweeney,Amira Klipnd are intercalated amongst myelin dense trapezoid body fiber tracts, limiting the use of brightfield optics to identify morphology of unlabeled neurons. Therefore, studies that allow careful analysis of synaptic inputs and intrinsic electrical properties of MOC neurons are lacking. Here, we describ作者: cuticle 時間: 2025-3-31 09:37 作者: 注視 時間: 2025-3-31 15:17 作者: 老人病學 時間: 2025-3-31 17:30 作者: 微不足道 時間: 2025-3-31 22:49
Betty Lamothe,Bertrand Duvillié,Nathalie Cordonnier,Anne Baudry,Susan Saint-Just,Danielle Bucchini,Jes of these specific cell types, revealing an unappreciated complexity in isoform variety in deafness-associated genes. Further application of this methodology may provide a more refined view of transcription in the organ of Corti, thereby improving our understanding of the biology of hearing and de作者: 責任 時間: 2025-4-1 05:02
Pascal Peraldi,Bruce Spiegelmanic procedure to obtain evoked mass-potential recordings using a minimally invasive procedure via the middle ear of awake subjects. In parallel, several stimulus and analysis paradigms were developed to target specific peripheral auditory properties such as frequency selectivity, phase-locking, and e作者: 有斑點 時間: 2025-4-1 07:55 作者: climax 時間: 2025-4-1 12:43 作者: 發(fā)芽 時間: 2025-4-1 15:20 作者: 改正 時間: 2025-4-1 21:30
Insulin receptor internalization and signalling,somal IRKs are exclusively activated has revealed that IRKs at this intracellular locus are able by themselves to promote IRS-1 tyrosine phosphorylation and induce hypoglycemia. Furthermore, studies with isolated rat adipocytes reveal the EN to be the principle site of insulin-stimulated IRS-1 tyros
