標(biāo)題: Titlebook: Hypoxia and the Circulation; Robert C. Roach (Research Director),Peter D. Wagne Conference proceedings 2007 The Editor(s) (if applicable) [打印本頁] 作者: BREED 時間: 2025-3-21 18:15
書目名稱Hypoxia and the Circulation影響因子(影響力)
書目名稱Hypoxia and the Circulation影響因子(影響力)學(xué)科排名
書目名稱Hypoxia and the Circulation網(wǎng)絡(luò)公開度
書目名稱Hypoxia and the Circulation網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Hypoxia and the Circulation被引頻次
書目名稱Hypoxia and the Circulation被引頻次學(xué)科排名
書目名稱Hypoxia and the Circulation年度引用
書目名稱Hypoxia and the Circulation年度引用學(xué)科排名
書目名稱Hypoxia and the Circulation讀者反饋
書目名稱Hypoxia and the Circulation讀者反饋學(xué)科排名
作者: 山羊 時間: 2025-3-21 23:31 作者: 吸氣 時間: 2025-3-22 03:37
https://doi.org/10.1007/978-3-642-17803-0 as arterial O2 tension (hypoxia). Progressive hypoxemia results in graded coronary vasodilation that is significantly more pronounced when arterial O. tension falls below 40?mmHg. Microvascular studies have demonstrated that O. has direct effects on vascular smooth muscle likely mediated by O. sens作者: outrage 時間: 2025-3-22 07:55 作者: Hirsutism 時間: 2025-3-22 09:25
https://doi.org/10.1007/978-3-540-89573-2ttent hypoxia (IH) and asphyxia, and leading also to sleep fragmentation due to the recurrent nocturnal arousals necessary to relieve the upper airway obstruction. In addition to cardiovascular and metabolic morbidities, OSAS also causes serious neurocognitive daytime dysfunction and is associated w作者: 雄偉 時間: 2025-3-22 16:43 作者: Ingenuity 時間: 2025-3-22 19:12
https://doi.org/10.1007/978-3-642-41616-3ls leads to apoptosis or epithelial-mesenchymal transdifferentiation. This in turn exacerbates fibrosis of the kidney with loss of peritubular capillaries and subsequent chronic hypoxia, setting in train a vicious cycle whose end point is ESRD. To support this notion, our studies utilizing various t作者: muscle-fibers 時間: 2025-3-23 00:15
https://doi.org/10.1007/978-3-662-10937-3icated by alveolar hypoxia, such as bronchopulmonary dysplasia (BPD), are at risk for developing pulmonary hypertension, which leads to right heart failure and greatly increases morbidity and mortality. We review the evidence that reactive oxygen species (ROS) are generated by pulmonary vascular wal作者: Cumbersome 時間: 2025-3-23 04:41
https://doi.org/10.1007/978-3-662-65850-5 vessel wall and remodelling of the extracellular matrix. This is crucial to ensure that sufficient blood can reach the developing fetus. Impaired arterial remodelling is a feature of the major pregnancy pathologies pre-eclampsia and fetal growth restriction. Despite its importance, little is known 作者: hemoglobin 時間: 2025-3-23 08:03
https://doi.org/10.1007/978-3-642-99067-0pe II and possibly type I cells. The rate-limiting step in this process is the activity of the heterotrimeric apical membrane epithelial Na+ channel (ENaC). Pharmacologic inhibitors and genetic manipulations that disrupt Na+ transport result in fluid accumulation within the lung and failure of gas e作者: Platelet 時間: 2025-3-23 10:46
https://doi.org/10.1007/978-3-658-40045-3a minimum amount of extravascular water. The maintenance of a minimum water volume is due to mechanisms able to control interstitial fluid turnover and to offset transient conditions of increase in this volume. The hydraulic pressure in the lung interstitium is ~ -10 cmH.O and reflects the equilibri作者: FLIC 時間: 2025-3-23 14:01
https://doi.org/10.1007/978-90-313-7191-4veolar flooding is associated with a decrease in edema fluid clearance and increased mortality. The mechanisms that lead to the impairment of alveolar fluid clearance are not completely understood. Alveolar fluid reabsorption is accomplished mostly by active Na+ transport across the alveolar epithel作者: Filibuster 時間: 2025-3-23 19:36
https://doi.org/10.1007/978-3-662-64621-2iological roles are still uncertain. Here we review the expression of Ngb and Cygb, with particular emphasis on their regulation and potential role under hypoxia. Ngb expression is confined to neurons and some endocrine tissues. At the subcellular level, Ngb is associated with the presence of mitoch作者: dermatomyositis 時間: 2025-3-24 00:53
https://doi.org/10.1007/978-3-658-13865-3otein and numerous studies have established that it has an essential role in facilitated oxygen transport in striated muscles. Recent strategies, using gene disruption technologies, have produced mice that lack myoglobin. These myoglobin deficient mice have a binary phenotype and a subpopulation of 作者: GREG 時間: 2025-3-24 02:23
Annotationen zu David Wellberys Thesen,izing machinery and with limited energy metabolism. While a number of genetic mechanisms can result in decreased hemoglobin concentration in the blood, this review concentrates on those that lead to increased hemoglobin mass, i.e. polycythemia or erythrocytosis. Polycythemia may be due to a) mutatio作者: tooth-decay 時間: 2025-3-24 10:13
https://doi.org/10.1007/978-3-662-32579-7tinguished by the presence of an open phase in which the spiracular valves are fully open, a closed phase during which oxygen concentrations at the tissues are lowered, thereby reducing oxidative damage, and a flutter phase in which the spiracles open intermittently for very brief periods,. The flut作者: 逃避責(zé)任 時間: 2025-3-24 11:15 作者: 招惹 時間: 2025-3-24 17:07 作者: Provenance 時間: 2025-3-24 21:14
Ist die Syphilis eine heilbare Krankheit?,functional consequences of the exercise-induced changes in gene expression. Muscle cells are able to detect mechanical, metabolic, neuronal and hormonal signals which are transduced over multiple pathways to the muscle genome. Exercise activates many signaling cascades - the individual characteristi作者: Collision 時間: 2025-3-24 23:18
Risk of Cardiovascular Events During Mountain Activities,goal of the present study was the identification of risk factors and triggers associated with SCDs during these mountain activities. Besides recording individual circumstances associated with SCD, a case-control study was performed comparing the risk factor profiles of 247 males over the age of 34 w作者: choleretic 時間: 2025-3-25 04:35
Biventricular Function at High Altitude: Implications for Regulation of Stroke Volume in Chronic Hyme is associated with reduction in left ventricular dimensions and filling pressure. An obvious explanation for this is the reduction in plasma volume observed at high altitude, but this does not appear to be the whole story. Neither is left ventricular systolic function abnormal even at the summit 作者: Arteriography 時間: 2025-3-25 10:44 作者: 纖細(xì) 時間: 2025-3-25 15:05
Metabolic Consequences Of Intermittent Hypoxia, or Syndrome X. Insulin resistance is also the primary risk factor for the development of type 2 diabetes mellitus, which is currently reaching epidemic proportions by affecting more than 170 million people worldwide. A combination of environmental and genetic factors have led to a dramatic rise in 作者: 音樂等 時間: 2025-3-25 16:41 作者: Cleave 時間: 2025-3-25 21:23
Vascular Consequences of Intermittent Hypoxia,out the day. Animal models have shown that this hypertensive effect requires an intact sympathetic nervous system and an intact carotid chemoreceptor reflex. The reninangiotensin system contributes importantly to hypertension in this model, because renal nerve denervation, angiotensin II receptor bl作者: 讓空氣進入 時間: 2025-3-26 00:09 作者: extract 時間: 2025-3-26 08:20 作者: 不近人情 時間: 2025-3-26 09:06 作者: 縱火 時間: 2025-3-26 16:10
,Epithelial Sodium Channels in the Adult Lung – Important Modulators of Pulmonary Health and Diseasepe II and possibly type I cells. The rate-limiting step in this process is the activity of the heterotrimeric apical membrane epithelial Na+ channel (ENaC). Pharmacologic inhibitors and genetic manipulations that disrupt Na+ transport result in fluid accumulation within the lung and failure of gas e作者: 館長 時間: 2025-3-26 20:52 作者: HEDGE 時間: 2025-3-27 00:35 作者: 吸氣 時間: 2025-3-27 01:29 作者: arterioles 時間: 2025-3-27 09:20 作者: 重畫只能放棄 時間: 2025-3-27 12:00
GenetiC Mechanisms Underlying Regulation of Hemoglobin Mass,izing machinery and with limited energy metabolism. While a number of genetic mechanisms can result in decreased hemoglobin concentration in the blood, this review concentrates on those that lead to increased hemoglobin mass, i.e. polycythemia or erythrocytosis. Polycythemia may be due to a) mutatio作者: Observe 時間: 2025-3-27 13:51
Control of the Respiratory Pattern in Insects,tinguished by the presence of an open phase in which the spiracular valves are fully open, a closed phase during which oxygen concentrations at the tissues are lowered, thereby reducing oxidative damage, and a flutter phase in which the spiracles open intermittently for very brief periods,. The flut作者: PLE 時間: 2025-3-27 21:34
Effects of Insect Body Size on Tracheal Structure and Function,eologic estimates suggest that atmospheric oxygen in the late Paleozoic Era was 35%. These findings have led to a prominent hypothesis that insect body size may be limited by oxygen delivery. Empirical evidence from developing . grasshopper experiments suggests that larger/older animals are not more作者: alcoholism 時間: 2025-3-28 00:19
The Role of Hif-1 1 in Hypoxic Response in the Skeletal Muscle,ve its function through that stress is central to its role in the body. The primary transcriptional response factor for hypoxic adaptation is hypoxia inducible factor-1α (HIF- 1α), which upregulates glycolysis and angiogenesis in response to low levels of tissue oxygenation. To examine the role of H作者: Expressly 時間: 2025-3-28 02:55
Gene Expression in Working Skeletal Muscle,functional consequences of the exercise-induced changes in gene expression. Muscle cells are able to detect mechanical, metabolic, neuronal and hormonal signals which are transduced over multiple pathways to the muscle genome. Exercise activates many signaling cascades - the individual characteristi作者: Asymptomatic 時間: 2025-3-28 08:37
0065-2598 omedicine. Hypoxia is a constant threat to the human body and its vital organs throughout life. There are many situations in which the threat is heightened in health and disease, but mechanisms have evolved to lessen its detrimental effects. ..The International Hypoxia Symposia was founded to enable作者: ADOPT 時間: 2025-3-28 12:17 作者: Aspirin 時間: 2025-3-28 18:16
Conference proceedings 2007nd its vital organs throughout life. There are many situations in which the threat is heightened in health and disease, but mechanisms have evolved to lessen its detrimental effects. ..The International Hypoxia Symposia was founded to enable scientists, clinicians, physiologists, immunologists, moun作者: Water-Brash 時間: 2025-3-28 22:23 作者: Indebted 時間: 2025-3-29 02:11
978-1-4419-4527-3The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines作者: 遠(yuǎn)足 時間: 2025-3-29 05:44 作者: Biomarker 時間: 2025-3-29 08:30
Robert C. Roach (Research Director),Peter D. Wagnelatest advances in hypoxia research and treatment作者: 不成比例 時間: 2025-3-29 11:29
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/h/image/430813.jpg作者: 抗原 時間: 2025-3-29 17:28
0065-2598 sophisticated research at the very highest levels into the many effects of hypoxia on humans and animals in health and disease..978-1-4419-4527-3978-0-387-75434-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 同來核對 時間: 2025-3-29 23:44
https://doi.org/10.1007/978-3-322-91173-5 occurrence of unconsciousness. Hikers who died suddenly during mountain hiking were much more likely to have had a prior myocardial infarction (MI) (17 % vs. 0.9 %), known coronary artery disease (CAD) without prior MI (17 % vs. 4 %), diabetes (6 % vs. 1 %), hypercholesterolemia (54 % vs. 20 %), an作者: 抑制 時間: 2025-3-30 03:54
https://doi.org/10.1007/978-3-658-07876-8eft ventricular filling as a consequence of right ventricular pressure overload, and hence reduce stroke volume. It is questionable how clinically significant is this left ventricular diastolic dysfunction. The relative importance of different mechanisms which reduce stroke volume probably depends w作者: 符合你規(guī)定 時間: 2025-3-30 06:47 作者: 抑制 時間: 2025-3-30 11:13
Victor D. K?chli,Borut Marinceked epidemiologic studies have shown associations, often independent of obesity, between SA (or surrogates such as snoring) and measures of glucose dysregulation or type 2 diabetes. However, treatment of SA with continuous positive airway pressure (CPAP) has not been conclusive in demonstrating impro作者: Awning 時間: 2025-3-30 13:42 作者: 文藝 時間: 2025-3-30 19:08
https://doi.org/10.1007/978-3-662-13435-1s are also present. Thus, oxidant stress and inflammation are potential mediators of intermittent hypoxia-induced vascular dysfunction. Once the mechanisms of intermittent hypoxia-induced alterations in vascular structure and function are understood, strategies can be developed to reverse or prevent作者: FLIC 時間: 2025-3-31 00:09
https://doi.org/10.1007/978-3-642-41616-3tion of RAS is especially important because it can lead to constriction of efferent arterioles, hypoperfusion of postglomerular peritubular capillaries, and subsequent hypoxia of the tubulointerstitium in the downstream compartment. Recent studies using BOLD-MRI showed an immediate decrease of oxyge作者: 徹底檢查 時間: 2025-3-31 01:18 作者: corn732 時間: 2025-3-31 07:12
https://doi.org/10.1007/978-3-662-65850-5 uteroplacental environment will vary with gestational age and will depend on the extent of trophoblast invasion and artery remodelling. Fluctuations in oxygen tension may be an important determinant of cellular events both during invasion towards uterine vessels and during the remodelling process. 作者: 刺穿 時間: 2025-3-31 10:52
https://doi.org/10.1007/978-3-642-99067-0al bronchiolitis) and reactive species (in acute lung injury). Finally, βadrenergic agonists have been shown experimentally to reverse defects in ENaC function, and improve hypoxemia and pulmonary edema, and may provide a novel therapeutic modality for ARDS, although some viral lung pathogens appear作者: 無聊點好 時間: 2025-3-31 16:35
https://doi.org/10.1007/978-3-658-40045-3lular matrix thanks to the mechanical role of matrix chondroitin sulphate proteoglycans (CS-PGs). This increase in pressure buffers microvascular filtration. Hypoxia causes fragmentation of CS-PGs of the extracellular matrix and of HS-PGs of the basement membrane: the result is a decrease in tissue 作者: 災(zāi)難 時間: 2025-3-31 20:00
https://doi.org/10.1007/978-90-313-7191-4s mediated by the generation of mitochondrial reactive oxygen species (ROS) as shown by pharmacological and genetic approaches. Hypoxia and ROS promote the PKC-zeta dependent phosphorylation of the Na,K-ATPase alpha subunit triggering its endocytosis in a clathrin–AP2 dependent process. The phosphor作者: 鞭子 時間: 2025-3-31 22:00
https://doi.org/10.1007/978-3-662-64621-2s (e.g. the mole rat Spalax and goldfish) express more Ngb in their brains than their oxygen-deprivation sensitive relatives. These data suggest that Ngb may have a myoglobin-like role and supplies oxygen to the respiratory chain of the metabolically highly active neurons, or protect them from react作者: antidepressant 時間: 2025-4-1 02:34 作者: ARCHE 時間: 2025-4-1 06:13 作者: custody 時間: 2025-4-1 10:15
https://doi.org/10.1007/978-3-662-32579-7tical parameters influencing the pattern are 1) the partial pressure of oxygen in the surrounding atmosphere, and 2) the rate of oxygen use i.e. the aerobic metabolic rate. Insects exhibit the DGC when the tracheal system is capable of delivering oxygen during the open phase at a rate faster than it作者: PANEL 時間: 2025-4-1 17:44
https://doi.org/10.1007/978-3-531-92207-2ote increased diffusive oxygen delivery. Using real time x-ray synchrotron phase-contrast analysis, we have found that larger/older grasshoppers also have a greater proportional volume of abdominal tracheae and air sacs per body mass than smaller/younger grasshoppers to enhance convective oxygen del作者: exophthalmos 時間: 2025-4-1 18:38
https://doi.org/10.1007/978-3-662-32578-0and elevated oxidative enzyme activities. These changes correlate with constitutively activated AMP-activated protein kinase in the HIF-1α null muscles. Additionally, HIF-1α null muscles have decreased expression of pyruvate dehydrogenase kinase I, a HIF-1α target that inhibits oxidative metabolism.
