標(biāo)題: Titlebook: Hypoxia and Cancer Metastasis; Daniele M. Gilkes Book 2019 Springer Nature Switzerland AG 2019 hypoxia.cancer.HIF.metastasis.angiogenesis [打印本頁] 作者: choleric 時間: 2025-3-21 18:30
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書目名稱Hypoxia and Cancer Metastasis網(wǎng)絡(luò)公開度
書目名稱Hypoxia and Cancer Metastasis網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Hypoxia and Cancer Metastasis被引頻次
書目名稱Hypoxia and Cancer Metastasis被引頻次學(xué)科排名
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書目名稱Hypoxia and Cancer Metastasis讀者反饋學(xué)科排名
作者: 連接 時間: 2025-3-21 21:17
Clinical and Pre-clinical Methods for Quantifying Tumor Hypoxia,complexity and heterogeneity across tumor types and individuals. Most standard imaging techniques can be modified and applied to measuring hypoxia and quantifying its effects; however, the benefits and challenges of each imaging modality makes imaging hypoxia case-dependent. In this chapter, a compr作者: TSH582 時間: 2025-3-22 03:34
Hypoxia and the Metastatic Niche,ass immune surveillance and propagate. Endothelial cell-to-cell junctions of blood vessels are loosened to enhance the penetrance of metastatic cancer cells to the metastatic sites. Different metastatic tissues have unique ECM constituents, resident immune cells, and anatomical positions linked with作者: obsolete 時間: 2025-3-22 07:08
Mechanistic Justifications of Systemic Therapeutic Oxygenation of Tumors to Weaken the Hypoxia Induent cancer immunotherapies without simultaneous administration of anti-Hypoxia-A2A-Adenosinergic drugs that inactivate this tumor-protecting mechanism in hypoxic and adenosine-rich tumors..Here, we overview the supporting evidence for the conceptually novel immunotherapeutic motivation to breathe su作者: 正面 時間: 2025-3-22 09:35
Wie aus der Zahl ein Zebra wirdcomplexity and heterogeneity across tumor types and individuals. Most standard imaging techniques can be modified and applied to measuring hypoxia and quantifying its effects; however, the benefits and challenges of each imaging modality makes imaging hypoxia case-dependent. In this chapter, a compr作者: Root494 時間: 2025-3-22 16:16
Rechnungslegung nach dem neuen Aktiengesetz,ass immune surveillance and propagate. Endothelial cell-to-cell junctions of blood vessels are loosened to enhance the penetrance of metastatic cancer cells to the metastatic sites. Different metastatic tissues have unique ECM constituents, resident immune cells, and anatomical positions linked with作者: FIG 時間: 2025-3-22 20:02 作者: ellagic-acid 時間: 2025-3-23 01:08 作者: follicle 時間: 2025-3-23 01:38 作者: 座右銘 時間: 2025-3-23 07:19
0065-2598 metastasis.Provides current approaches used clinically and p.The present book is an attempt to provide a detailed review of studies that clarify our current understanding of the role of hypoxia in the progression of primary cancer to metastatic disease. It will enable researchers to discover the cri作者: Sad570 時間: 2025-3-23 12:05 作者: reject 時間: 2025-3-23 15:43
Hypoxia Mediates Tumor Malignancy and Therapy Resistance,reprogramming, immune evasion, pH homeostasis, cell migration/invasion, stem cell pluripotency, and therapy resistance. In this book chapter, we reviewed the causes and types of intratumoral hypoxia, hypoxia detection methods, and the oncogenic role of HIF in tumorigenesis and chemo- and radio-therapy resistance.作者: GLIDE 時間: 2025-3-23 22:03
Bibliothek des Radio Amateurs (geschlossen)demonstrated an important functional role for HIF signaling in driving CSC, metastatic and drug resistant phenotypes . and .. Here we will review recent studies that highlight novel mechanisms by which hypoxia promotes cancer stem cell, metastatic and drug resistant phenotypes.作者: intelligible 時間: 2025-3-24 00:38
Kurt Hesse,Rolf Fraling,Wolfgang Fralinganisms by which intratumoral hypoxia regulates the expression of motogenic and mitogenic factors that induce angiogenesis and lymphangiogenesis, whilst discussing their implications for metastatic cancers.作者: filial 時間: 2025-3-24 03:50 作者: MURAL 時間: 2025-3-24 08:17 作者: separate 時間: 2025-3-24 12:27 作者: Fulminate 時間: 2025-3-24 17:29
Hypoxia and Metabolism in Metastasis,us, adapts to decreased oxygen availability as a transcriptional factor. HIF-1 regulates many genes involved in tumorigenesis. Here, we focus on cancer cell metabolism and metastasis regulated by hypoxia.作者: antipsychotic 時間: 2025-3-24 21:13 作者: Accessible 時間: 2025-3-25 01:50 作者: 圣歌 時間: 2025-3-25 06:40
Hypoxia and the Tumor Secretome,condary sites. Here we review current evidence for a hypoxia-induced tumor secretome and its impact on metastatic progression. These studies have identified potential biomarkers and therapeutic targets that could be integrated into strategies for preventing and treating metastatic disease.作者: 泄露 時間: 2025-3-25 09:06
Therapeutic Strategies to Block the Hypoxic Response,FR/HER2 inhibitors?also exist. Despite the existence of many therapeutics to combat the hypoxic response, there has been very little success in late phase clinical trials, potentially due to a lack of biomarkers that can be used to stratify patients who would benefit from a hypoxia-targeted therapy.作者: CRAB 時間: 2025-3-25 13:46
Hans J. Kleinsteuber,Meike Friesxygen (hypoxia) in malignant progression, and how hypoxia can be a significant factor in the development of drug resistance. We conclude by proposing potential therapeutic approaches that take advantage of a hypoxic microenvironment to chemosensitize therapy-resistant tumours.作者: 伴隨而來 時間: 2025-3-25 16:01
Hypoxia-Induced Resistance to Chemotherapy in Cancer,xygen (hypoxia) in malignant progression, and how hypoxia can be a significant factor in the development of drug resistance. We conclude by proposing potential therapeutic approaches that take advantage of a hypoxic microenvironment to chemosensitize therapy-resistant tumours.作者: CURT 時間: 2025-3-25 21:39
Das passende Schaubild finden ...,r of intratumoral hypoxia and controls hypoxia-mediated pathological processes in tumors, including angiogenesis, metabolic reprogramming, epigenetic reprogramming, immune evasion, pH homeostasis, cell migration/invasion, stem cell pluripotency, and therapy resistance. In this book chapter, we revie作者: 退潮 時間: 2025-3-26 02:14 作者: 團(tuán)結(jié) 時間: 2025-3-26 04:30
Bibliothek des Radio Amateurs (geschlossen)he tumor microenvironment is strongly influenced by microenvironmental factors such as hypoxia. Clinically, hypoxia and the hypoxia inducible transcription factors HIF-1 and HIF-2 are associated with cancer stem cells, metastasis and drug resistance in multiple tumor types. Experimental models have 作者: 匍匐前進(jìn) 時間: 2025-3-26 11:58
https://doi.org/10.1007/978-3-322-91055-4ic options will become available only if we enhance our understanding of mechanisms underlying metastatic spread. A large body of literature shows that the metastatic potential of tumor cells is strongly influenced by microenvironmental cues such as low oxygen (hypoxia). Clinically, hypoxia is a hal作者: 凝乳 時間: 2025-3-26 16:30
Kurt Hesse,Rolf Fraling,Wolfgang Fralingmetastatic disease and mortality owing to its ability to stimulate the formation of blood (angiogenesis) and lymphatic vessels (lymphangiogenesis), thereby allowing cancer cells to escape the unfavorable tumor microenvironment and disseminate into secondary sites. This review outlines molecular mech作者: Obstruction 時間: 2025-3-26 18:35 作者: 推測 時間: 2025-3-26 21:56 作者: 細(xì)頸瓶 時間: 2025-3-27 02:17 作者: 贊美者 時間: 2025-3-27 07:50 作者: 一致性 時間: 2025-3-27 10:54 作者: Bravado 時間: 2025-3-27 15:54 作者: scotoma 時間: 2025-3-27 19:01
Clinical and Pre-clinical Methods for Quantifying Tumor Hypoxia,e term hypoxia has two definitions. One definition would be a physiologic state where the oxygen partial pressure is below the normal physiologic range. For most normal tissues, the normal physiologic range is between 10 and 20?mmHg. Hypoxic regions develop when there is an imbalance between oxygen 作者: 逃避系列單詞 時間: 2025-3-28 01:41 作者: 鐵塔等 時間: 2025-3-28 05:34
Hypoxia and the Tumor Secretome,ic options will become available only if we enhance our understanding of mechanisms underlying metastatic spread. A large body of literature shows that the metastatic potential of tumor cells is strongly influenced by microenvironmental cues such as low oxygen (hypoxia). Clinically, hypoxia is a hal作者: sperse 時間: 2025-3-28 09:09 作者: 絆住 時間: 2025-3-28 12:49
Hypoxia and Metabolism in Metastasis, a large number of target genes involved in cell growth, metabolism, metastasis and immunity are activated in cancer cells. Hypoxia-inducible factor 1 (HIF-1), as a heterodimeric DNA-binding complex, is comprised of a constitutively expressed HIF-1β subunit and an oxygen sensitive HIF-1α subunit, th作者: BLAZE 時間: 2025-3-28 16:09
Hypoxia and the Metastatic Niche,vely remodeled by secretory factors including growth factors, chemokines and cytokines, extracellular matrix (ECM) enzymes, and exosomes produced by the primary cancer tissues. Many of the associated-secretory factors are abundantly induced by inflammation and hypoxia. These secretory factors modify作者: mortuary 時間: 2025-3-28 21:41 作者: impaction 時間: 2025-3-29 02:55
Hypoxia-Induced Resistance to Chemotherapy in Cancer, property of malignant cells developed prior to therapy, or acquired following exposure to anti-cancer drugs. Given the impact of drug resistance to the overall poor survival of cancer patients, there is an urgent need to better understand the molecular pathways regulating this malignant phenotype. 作者: somnambulism 時間: 2025-3-29 03:06 作者: GNAT 時間: 2025-3-29 09:08 作者: PALMY 時間: 2025-3-29 13:51
