作者: Canyon 時間: 2025-3-21 23:18
Hydrogen technologies in mobility and transportation,作者: APRON 時間: 2025-3-22 03:56 作者: 收集 時間: 2025-3-22 06:34
Production of PEM systems, upscaling and rollout strategy,作者: champaign 時間: 2025-3-22 11:16 作者: arcane 時間: 2025-3-22 16:02
Digitalization and simulation of hydrogen technologies,作者: 善于 時間: 2025-3-22 18:23
Hydrogen technologies in the energy system: the international perspective,作者: 憎惡 時間: 2025-3-22 21:50
Hydrogen technologies: outlook and future possibilities,作者: 完成 時間: 2025-3-23 01:48 作者: 盲信者 時間: 2025-3-23 07:31 作者: vanquish 時間: 2025-3-23 13:19
Reimund Neugebaueret captures nonlinear effects of multi-omics data to survival outcomes via a neural network framework, while allowing one to biologically interpret the model. In the extensive experiments with multi-omics data of Gliblastoma multiforme (GBM) patients, MiNet outperformed the current cutting-edge meth作者: Decibel 時間: 2025-3-23 13:55
Simon Harst,Bernhard A?mus,Angelika Hackner,Anja Haslingeris used to calculate the relational initial scores for new drugs. To systematically evaluate the prediction performance of IDNDDI and compare it with other prediction methods, we conduct the 5-fold cross validation and de novo drug validation. In terms of the AUC (area under the ROC curve)value, IDN作者: CBC471 時間: 2025-3-23 19:14
Martin Wietschel,Elisabeth Dütschke,Marius Neuwirth,Aline Scherrer,Lin Zheng,Norman Gerhardt,Sebastial information. Also, the partner antigen is vital for paratope prediction, and we employ Att-BLSTM on the partner antigen sequence as well. The outputs of CNNs and Att-BLSTM networks are combined to predict antibody paratope by fully-connected networks. The experiments show that our proposed method作者: 出處 時間: 2025-3-24 01:29
Jochen Bard,Norman Gerhardt,Marie Plaisir,Ramona Schr?er,Anne Held,Hans-Martin Henning,Christoph Koso-layer RGCN to predict microbe-disease associations. Compared with other methods, TNRGCN achieves a good performance in cross validation. Meanwhile, case studies for diseases demonstrate TNRGCN has a good performance for predicting potential microbe-disease associations.作者: Needlework 時間: 2025-3-24 05:51 作者: 冒號 時間: 2025-3-24 10:15
Ulf Groos,Malte Semmel,Achim Schaadt,Stefan Bürger,Felix Horch,Johannes Geiling,Richard ?chsner,Gunt.We conducted a series of simulation experiments to assess the performance of . and compared it against previously existing probabilistic methods (.) and parsimonious methods (.). As we learned from the results, . can reconstruct more correct ancestral adjacencies and yet run several orders of magni作者: 音樂學者 時間: 2025-3-24 12:27 作者: Spirometry 時間: 2025-3-24 18:47
Ulrike Herrmann,Natalia Pieton,Benjamin Pfluger,Katharina Alms,Tanja Manuela Kneiske,Christopher VogrRWMDE, takes several steps of random walking on three different biological networks, microRNA-microRNA functional similarity network(MFN), disease-disease similarity network(DSN) and environmental factor similarity network(ESN) respectively so as to get microRNA-disease association information from作者: 甜瓜 時間: 2025-3-24 21:25
Sebastian Metz,Tom Smolinka,Christian I. Bern?cker,Stefan Loos,Thomas Rauscher,Lars R?ntzsch,Michaeleins. It is the same way with S-PIN and NF-APIN. NF-APIN is a dynamic PIN constructed by using gene expression data and S-PIN. The experimental results on the protein interaction network of S.cerevisiae shows that all the six network-based methods achieve better results when being applied on TS-PIN 作者: 直覺好 時間: 2025-3-25 01:15
Ulf Groos,Carsten Cremers,Laura Nousch,Christoph Baumg?rtnere true biological mutations. HapIso uses a k-means clustering algorithm aiming to group the reads into two meaningful clusters maximizing the similarity of the reads within cluster and minimizing the similarity of the reads from different clusters. Each cluster corresponds to a parental haplotype. W作者: conduct 時間: 2025-3-25 05:05
Ulrike Beyer,Sebastian Porstmann,Christoph Baum,Clemens Müllerlt to cover and compare the predicted results with the empirical results (both simulated and real data) on human chromosomes. The results are promising, with most of the difficult regions correctly predicted. Tested on BioNano maps, our model is more accurate than the most popular existing error mod作者: 具體 時間: 2025-3-25 09:09 作者: FIS 時間: 2025-3-25 15:29
Christian Els?sser,Thorsten Michler,Peter Gumbsche classic structural variants that can be detected by state-of-the-art methods (e.g., SVIM and Sniffles), our experiments demonstrate recall improvements of up-to . without harming the precisions (i.e., above .). We also point out three directions to further improve structural variant detection in t作者: NEXUS 時間: 2025-3-25 18:00 作者: Locale 時間: 2025-3-25 23:21
Sylvia Schattauer,Alexander Spie?,Alexander Martin,Robert Burlacu,Gregor Herz,Christian Leith?user,Ugning 5’ and 3’ ends between two sequences simultaneously) to locate breakpoints which can solve the problems introduced by sequencing errors, micro-homologies and micro-insertions. For testing the performance of Sprites2, simulated and real datasets are used in our experiments, and some popular str作者: granite 時間: 2025-3-26 02:03
Christopher Hebling,Kira Schlüter,Ombeni Ranzmeyer,Norman Gerhardt,Maximilian Pfennig,Martin Wietscht designed to work with deletion or insertion mutations. Herein we develop an efficient approach, based on suboptimal folding solutions, to predict multiple point mutations consisting of deletions, insertions and substitution mutations. All RNAmute algorithms were validated on the TPP-riboswitch and作者: gospel 時間: 2025-3-26 04:46 作者: Harness 時間: 2025-3-26 09:54 作者: 大氣層 時間: 2025-3-26 15:56 作者: 厭倦嗎你 時間: 2025-3-26 20:16
Reimund Neugebauerer. Multi-omics data provide comprehensive descriptions of human genomes regulated by complex interactions of multiple biological processes such as genetic, epigenetic, and transcriptional regulation. Therefore, the integration of multi-omics data is essential to decipher complex mechanisms of human作者: 拋棄的貨物 時間: 2025-3-26 21:28
Simon Harst,Bernhard A?mus,Angelika Hackner,Anja Haslingerapeutic effect of patients. However, the negative DDIs can lead serious results, such as drug withdrawal from market and even patient death. Currently, multiple pharmaceutical drugs have widely been used to treat complex diseases, such as cancer. The traditional biomedical experiments are very time-作者: Filibuster 時間: 2025-3-27 03:19
Martin Wietschel,Elisabeth Dütschke,Marius Neuwirth,Aline Scherrer,Lin Zheng,Norman Gerhardt,Sebastin antigen, known as paratope, mediates antibody-antigen interaction with high affinity and specificity. And the accurate prediction of those regions from antibody sequence contributes to the design of therapeutic antibodies and remains challenging. However, the experimental methods are time-consumin作者: 修飾 時間: 2025-3-27 08:14 作者: CRAB 時間: 2025-3-27 12:20
Matthias Jahn,Gregor Herz,G?rge Deerberg,Christoph Glasner,Axel Kraft,Andreas Menne,Torsten Müller,Uorithms have been proposed, their performance is still limited by the characteristics of DR lesions and grading criteria, and coarse-grained image-level label. In this paper, we propose a novel approach based on contrastive learning and semi-supervised learning to break through these limitations. We作者: Type-1-Diabetes 時間: 2025-3-27 15:14 作者: 粗鄙的人 時間: 2025-3-27 21:47
Sebastian Herkel,Robert Meyer,Norman Gerhardtrucial role in biological research in the past decades, especially with the increasing availability of fully sequenced genomes. In general, phylogenetic analysis tries to solve two problems: Small Parsimony Problem (SPP) and Big Parsimony Problem (BPP). Maximum parsimony is a popular approach for SP作者: Essential 時間: 2025-3-28 00:14 作者: chastise 時間: 2025-3-28 04:48 作者: glamor 時間: 2025-3-28 09:09
Ulf Groos,Carsten Cremers,Laura Nousch,Christoph Baumg?rtnerrotocols generate multi-kilobase reads longer than most transcripts allowing sequencing of complete haplotype isoforms. This allows partitioning the reads into two parental haplotypes. While the read length of the single-molecule protocols is long, the relatively high error rate limits the ability t作者: 使增至最大 時間: 2025-3-28 13:39
Ulrike Beyer,Sebastian Porstmann,Christoph Baum,Clemens Müllerill critical questions left unanswered due to the intrinsic limitations of short read length. To address this issue, several new sequencing platforms came into view. However, a lack of comprehensive understanding of the sequencing error poses a primary challenge for their optimal use. Here, we focus作者: 凝結劑 時間: 2025-3-28 16:31 作者: Strength 時間: 2025-3-28 20:23
Christian Els?sser,Thorsten Michler,Peter Gumbschlogies arise to make it possible to find structural variants of as long as ten thousand nucleotides. Thus, long read based structural variant detection has been drawing attention of many recent research projects, and many tools have been developed for long reads to detect structural variants recentl作者: chandel 時間: 2025-3-29 02:39 作者: VALID 時間: 2025-3-29 04:14
Sylvia Schattauer,Alexander Spie?,Alexander Martin,Robert Burlacu,Gregor Herz,Christian Leith?user,Uzygous deletions is an important issue for current structural variation detection tools. Additionally, due to the problems of sequencing errors, micro-homologies and micro-insertions, breakpoint locations identified with common alignment tools which use greedy strategy may not be the true deletion l作者: 色情 時間: 2025-3-29 07:51 作者: 過時 時間: 2025-3-29 13:25
Uwe Spohn,Klemens Ilse,J?rg Kleeberg,Peter Michel,Sylvia Schattauer,Alexander Spie?,Ulrike Beyer,Det platform cancer data, which is capable of revealing intrinsic characteristics of a biological process, has become an attractive research route on cancer subtypes discovery. Most machine learning based methods need represent each input data in unified space, losing certain important features or resu作者: adhesive 時間: 2025-3-29 18:32
global conformational rearrangement of the secondary structure of the functional RNA molecules and thereby disrupt their function. RNAmute was designed to deal with only single point mutations in a brute force manner, while the MultiRNAmute tool uses an efficient approach to deal with multiple point作者: 要控制 時間: 2025-3-29 23:40 作者: 他姓手中拿著 時間: 2025-3-30 03:48
Book 2023limate-neutral industry processes and sustainable mobility. For Germany and Europe alike, they present an opportunity to maintain industrial value creation, expand export opportunities and secure technological sovereignty.?..In this book, the Fraunhofer-Gesellschaft presents the knowledge and experi作者: 潛移默化 時間: 2025-3-30 06:08 作者: ATP861 時間: 2025-3-30 08:50 作者: 駁船 時間: 2025-3-30 15:54 作者: Offset 時間: 2025-3-30 18:42 作者: GROG 時間: 2025-3-30 22:56 作者: Palpate 時間: 2025-3-31 02:25 作者: 幼稚 時間: 2025-3-31 06:46 作者: idiopathic 時間: 2025-3-31 10:28 作者: Feigned 時間: 2025-3-31 17:26
