作者: ostensible 時(shí)間: 2025-3-21 22:28
Silvia Graciela Ruginsk,Lucila Leico Kagohara Elias,José Antunes-Rodrigues,André Souza Mecawiolecular biology, surface biotechnology and biomaterials eng.Contemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conju作者: Agnosia 時(shí)間: 2025-3-22 01:06
Giovanna Mantovani,Alessandra Mangone,Elisa Salare efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology.? In this second edition of .Bioconjugation Prot作者: FILTH 時(shí)間: 2025-3-22 06:29 作者: Anticoagulants 時(shí)間: 2025-3-22 11:04 作者: PALMY 時(shí)間: 2025-3-22 14:04
Marianna Martino,Giulia Giancola,Giorgio Arnaldiolecular biology, surface biotechnology and biomaterials eng.Contemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conju作者: 名義上 時(shí)間: 2025-3-22 20:13
Emanuele Ferrante,Júlia Ferreira de Carvalhore efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology.? In this second edition of .Bioconjugation Prot作者: GRACE 時(shí)間: 2025-3-23 00:42 作者: pulse-pressure 時(shí)間: 2025-3-23 03:25
Alessandro Peri,Dario Norello,Benedetta Fibbire efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology.? In this second edition of .Bioconjugation Prot作者: 熒光 時(shí)間: 2025-3-23 08:39
Laetitia Martineriere efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology.? In this second edition of .Bioconjugation Prot作者: 發(fā)芽 時(shí)間: 2025-3-23 11:08
Sonir Roberto Rauber Antonini,Thais Milioni Lucianoolecular biology, surface biotechnology and biomaterials eng.Contemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conju作者: 側(cè)面左右 時(shí)間: 2025-3-23 16:37
Cristian A. Carvajal,Alejandra Tapia-Castillo,Thomas Uslar,Carlos E. Fardellaolecular biology, surface biotechnology and biomaterials eng.Contemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conju作者: heartburn 時(shí)間: 2025-3-23 20:56
Fabio Luiz Fernandes-Rosare efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology.? In this second edition of .Bioconjugation Prot作者: habitat 時(shí)間: 2025-3-24 02:04
Sheerazed Boulkroun,Maria-Christina Zennarore efficient means to control conjugation and the specific site of attachment of the conjugated moiety but also the effective use of recent developments in the fields of pharmaceutical chemistry, biomolecular/polymer engineering, and nanobiotechnology.? In this second edition of .Bioconjugation Prot作者: nutrition 時(shí)間: 2025-3-24 05:26
Andrea Armani,Massimiliano Caprioolecular biology, surface biotechnology and biomaterials eng.Contemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conju作者: Minuet 時(shí)間: 2025-3-24 08:52 作者: 強(qiáng)壯 時(shí)間: 2025-3-24 14:07
olecular biology, surface biotechnology and biomaterials eng.Contemporary approaches to the synthesis of chemically modified biomacromolecules (proteins, nucleic acids, lipids, and carbohydrates) not only require efficient means to control conjugation and the specific site of attachment of the conju作者: 埋葬 時(shí)間: 2025-3-24 17:21 作者: 不能妥協(xié) 時(shí)間: 2025-3-24 20:35 作者: SPALL 時(shí)間: 2025-3-25 00:58 作者: 共和國(guó) 時(shí)間: 2025-3-25 06:37 作者: Foreknowledge 時(shí)間: 2025-3-25 08:43
Diabetes Insipidus: Novel Diagnostic Approaches, polydipsia. The polyuria-polydipsia syndrome includes four major entities: central DI (CDI), gestational DI (GDI), nephrogenic DI (NDI), and primary polydipsia (PP). It is essential to differentiate accurately CDI from the other forms, because a wrong diagnosis can have fatal consequences. Clinical作者: 刪減 時(shí)間: 2025-3-25 14:39
Syndrome of Inappropriate Antidiuresis, several adverse outcomes..Syndrome of inappropriate antidiuresis (SIAD) is the most common cause of euvolemic hyponatremia, and its diagnosis requires compliance with a well-defined clinical and biochemical criteria..The choice of therapy for SIAD is guided by its underlying etiology and the initia作者: Expostulate 時(shí)間: 2025-3-25 17:12 作者: 冷漠 時(shí)間: 2025-3-25 20:02
Approach to Hyponatremia According to the Clinical Setting,the consequence of a relative excess of water compared to total body sodium, which can be reduced, normal or even increased. Because of its frequency and different causes, hyponatremia can be observed in virtually all possible clinical scenarios, encompassing medical as well as surgery specialties. 作者: Inculcate 時(shí)間: 2025-3-26 02:34
Electrolyte Disturbance in Congenital Adrenal Hyperplasia due to 21-OH Deficiency,um homeostasis, particularly in the neonatal period. The pathophysiology of this impaired sodium balance is still poorly investigated as well as its therapeutic management. This chapter will summarize mechanisms of sodium and water reabsorption, particularly the aldosterone-mineralocorticoid recepto作者: 失誤 時(shí)間: 2025-3-26 05:28
Rare Forms of Congenital Adrenal Hyperplasia Affecting Electrolyte Homeostasis, deficiency. However, rare forms of CAH, representing around 5% of cases, are attributed to five other enzymatic defects that disrupt steroidogenesis and impact electrolyte homeostasis..Enzymatic defects can occur at various stages of the steroidogenesis pathway, leading to impaired conversion of ch作者: 公社 時(shí)間: 2025-3-26 10:04
Apparent Mineralocorticoid Excess,ow-renin levels allowed the identification of two different clinical entities: aldosterone-mediated mineralocorticoid receptor (MR) activation and cortisol-mediated MR activation. The spectrum of cortisol-mediated MR activation includes the classic apparent mineralocorticoid excess?(AME) to milder (作者: Nomogram 時(shí)間: 2025-3-26 15:34
Mineralocorticoid Resistance,imulating sodium reabsorption in the distal nephron. Pseudohypoaldosteronism type 1 (PHA1) is a rare disease characterized by salt loss in the neonatal period secondary to a target organ resistance to mineralocorticoid action. Patients exhibit salt wasting in the neonatal period with failure to thri作者: 浪費(fèi)物質(zhì) 時(shí)間: 2025-3-26 17:26
Primary Aldosteronism,enal hyperplasia. Over the past 15?years, major advances have been made in our understanding of the disease with the identification of somatic and germline mutations responsible for the development of APA and of familial form of hyperaldosteronism. These mutations affect essentially ionic channels a作者: 粗魯性質(zhì) 時(shí)間: 2025-3-27 00:07
Mineralocorticoid Receptor and Aldosterone: From Hydro-saline Metabolism to Metabolic Diseases,phron. In the last 10 years, a number of preclinical studies has shown that MR is expressed also in extra-renal tissues such as heart, adipose tissue and vasculature, providing strong evidence that dysregulated extra-renal MR activation contributes to the development of hypertension, obesity, insuli作者: GROUP 時(shí)間: 2025-3-27 02:17 作者: APRON 時(shí)間: 2025-3-27 06:01 作者: microscopic 時(shí)間: 2025-3-27 10:13 作者: Pudendal-Nerve 時(shí)間: 2025-3-27 15:54 作者: 潛移默化 時(shí)間: 2025-3-27 20:07 作者: Alcove 時(shí)間: 2025-3-28 00:32 作者: DECRY 時(shí)間: 2025-3-28 03:40
Physiology of Vasopressin Secretion,erts its multiple effects by binding to its receptors, classified in different subtypes depending on tissue expression, function, and second messengers. Disorders in AVP synthesis or action can lead to clinical syndromes characterized by water and electrolyte imbalance.作者: 灌溉 時(shí)間: 2025-3-28 09:44 作者: Obvious 時(shí)間: 2025-3-28 10:30
Familial Hyperkalemic Hypertension (FHHt),t in vitro and in vivo studies have demonstrated that NCC is stimulated by a signaling pathway activated by WNK1 and WNK4, which are themselves targeted for proteosomal degradation by the Cul3-KLHL3 complex..Therefore, the study of this very rare and easily treatable syndrome has led to the discover作者: 躲債 時(shí)間: 2025-3-28 17:32 作者: overrule 時(shí)間: 2025-3-28 19:08 作者: 半身雕像 時(shí)間: 2025-3-29 00:21
Hydro-saline Alterations in Central Adrenal Insufficiency,luding both isolated ACTH deficiency and CAI in the context of combined pituitary hormonal deficiency (CPHD). Hyponatremia in CAI patients is usually mild, mainly asymptomatic, and more likely occurs in elderly patients, although careful evaluations should be performed in patients with acute hyponat作者: endure 時(shí)間: 2025-3-29 04:16
Rare Forms of Congenital Adrenal Hyperplasia Affecting Electrolyte Homeostasis,urthermore, the loss of function of 11-B-hydroxylase leads to no production of glucocorticoids and an excess of mineralocorticoids and androgens..The severity of these defects varies depending on the specific mutation carried by each individual, resulting in a wide range of manifestations that can p作者: impaction 時(shí)間: 2025-3-29 09:26 作者: 極小量 時(shí)間: 2025-3-29 13:50
Mineralocorticoid Resistance,PHA1 are associated with malformations in the urinary tract and/or urinary tract infections. PHA1 is a major differential diagnosis for salt wasting syndromes occurring in the first weeks after birth. The knowledge of its genetic background and pathophysiology may improve the early recognition of th作者: 彎曲道理 時(shí)間: 2025-3-29 18:28
Primary Aldosteronism,nt mouse models has also contributed to a better understanding of the molecular mechanisms involved in the development of PA. Finally, the use of multiomics signatures combined with machine learning appears to be a promising new tool for improving the diagnosis and management of endocrine hypertensi作者: flourish 時(shí)間: 2025-3-29 22:53 作者: magnate 時(shí)間: 2025-3-30 01:22
Hydrosaline Alterations in Cushing Disease, increased mortality in patients with Cushing’s syndrome: therefore, treatment must be initiated early and primarily involves the resolution of hypercortisolism through surgery and eventually cortisol-lowering medical therapy; if the regression of hypertension is not achieved, adjuvant antihypertens作者: AROMA 時(shí)間: 2025-3-30 07:33
a functionally important amino group in the antigen-binding region of an antibody causes impairment or loss of the antigen binding function, resulting in a defective antibody conjugate that lacks one of its component functions. Furthermore, even if the chemical derivatization does not affect the an作者: Hay-Fever 時(shí)間: 2025-3-30 09:48 作者: abreast 時(shí)間: 2025-3-30 13:20
Emanuele Ferrante,Júlia Ferreira de Carvalhopproaches.? Additional chapters address the biofunctionalization of surface structures, including organic/inorganic thin films, as well as various types of nanostructures (magnetic nanoparticles, quantum dots, carbon nanotubes, and silicon nanowire devices).? All the protocols follow the successful 作者: NAUT 時(shí)間: 2025-3-30 17:07
Alessandro Peri,Dario Norello,Benedetta Fibbipproaches.? Additional chapters address the biofunctionalization of surface structures, including organic/inorganic thin films, as well as various types of nanostructures (magnetic nanoparticles, quantum dots, carbon nanotubes, and silicon nanowire devices).? All the protocols follow the successful 作者: Bmd955 時(shí)間: 2025-3-30 23:17 作者: SPECT 時(shí)間: 2025-3-31 01:57
