標(biāo)題: Titlebook: Histone Deacetylases; Transcriptional Regu Eric Verdin Book 2006 Humana Press 2006 biochemistry.biology.cell.enzymes.proteins.vertebrates [打印本頁] 作者: 拿著錫 時(shí)間: 2025-3-21 17:56
書目名稱Histone Deacetylases影響因子(影響力)
書目名稱Histone Deacetylases影響因子(影響力)學(xué)科排名
書目名稱Histone Deacetylases網(wǎng)絡(luò)公開度
書目名稱Histone Deacetylases網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Histone Deacetylases被引頻次
書目名稱Histone Deacetylases被引頻次學(xué)科排名
書目名稱Histone Deacetylases年度引用
書目名稱Histone Deacetylases年度引用學(xué)科排名
書目名稱Histone Deacetylases讀者反饋
書目名稱Histone Deacetylases讀者反饋學(xué)科排名
作者: 增減字母法 時(shí)間: 2025-3-21 23:13
Biochemistry of Multiprotein HDAC Complexesfic restrictions to transcription and contributes to the proper coordination of gene expression. In order to perform these functions and to achieve proper modulation of their activity, HDACs associate with other proteins, and in some cases, even with themselves. The purification and analyses of thes作者: 騙子 時(shí)間: 2025-3-22 02:48 作者: Polydipsia 時(shí)間: 2025-3-22 06:08
Regulation of Muscle Gene Expression by Histone Deacetylaseseby limits access of basal transcriptional machinery to gene regulatory elements. In the past 5 years, HDACs have emerged as key regulators of gene expression in muscle. In this chapter, we discuss the initial findings linking HDACs to the control of striated muscle cell differentiation and growth. 作者: 暫時(shí)中止 時(shí)間: 2025-3-22 12:08 作者: slipped-disk 時(shí)間: 2025-3-22 15:54 作者: 最高峰 時(shí)間: 2025-3-22 18:02
Evolution of Sirtuins From Archaea to Vertebratesd the echinoderm sea urchin ., there are seven sirtuins. Class I includes SIRT1, SIRT2, and SIRT3. SIRT4 is in class II and SIRT5 is in class III. Class IV includes SIRT6 and SIRT7. Fish have two SIRT5 orthologs while most other vertebrates have only one version of each of the seven sirtuins. Arthro作者: judiciousness 時(shí)間: 2025-3-22 23:26 作者: Androgen 時(shí)間: 2025-3-23 04:39
The Enzymology of SIR2 Proteinse, the deacetylated product, and .-acetyl-ADP-ribose. An increasing number of cellular processes including apoptosis, cell cycling, gene silencing, and longevity, have been shown to be dependent and regulated by these deacetylases. Several small molecules have been identified as regulators of Sir2 a作者: Mingle 時(shí)間: 2025-3-23 07:29
The Class III Protein Deacetylasesiptional regulator Sir2. In eukaryotes, sirtuins regulate The first two authors contributed equally to this review. transcriptional repression, recombination, cell cycle division, microtubule organization, and cellular responses to DNA-damaging agents. Sir2 proteins have also been implicated in regu作者: figment 時(shí)間: 2025-3-23 12:00
HDAC Inhibitorson of their functions but have also developed as attractive therapeutic agents for diseases including cancer. After the disclosure of the crystal structure of the HDAC-like protein bound to the inhibitor, the momentum of research on HDAC inhibitors increased, and several inhibitors are currently und作者: heterodox 時(shí)間: 2025-3-23 17:00 作者: insincerity 時(shí)間: 2025-3-23 20:05 作者: exquisite 時(shí)間: 2025-3-24 02:09 作者: 切掉 時(shí)間: 2025-3-24 05:31 作者: Mere僅僅 時(shí)間: 2025-3-24 09:38 作者: 暴發(fā)戶 時(shí)間: 2025-3-24 14:17 作者: 芳香一點(diǎn) 時(shí)間: 2025-3-24 17:03
Margie T. Borra PhD,John M. Denu PhDbject; we have not attempted an encyclopedic treatment. In Book I, we focus on preliminaries. Chapter 1 provides an introduction to multivariable calculus and treats the Inverse Function Theorem, Implicit Function Theorem, the theory of the Riemann Integral, and the Change of Variable Theorem. Chapt作者: Inordinate 時(shí)間: 2025-3-24 21:09 作者: ALB 時(shí)間: 2025-3-24 23:24 作者: COW 時(shí)間: 2025-3-25 06:59
Akihiro Ito PhD,Norikazu Nishino PhD,Minoru Yoshida PhDhave not attempted an encyclopedic treatment. Book II deals with more advanced material than Book I and is aimed at the graduate level. Chapter 4 deals with additional topics in Riemannian geometry. Properties of real analytic curves given by a single ODE and of surfaces given by a pair of ODEs are 作者: noxious 時(shí)間: 2025-3-25 11:05
Brian Gabrielli PhDomothety homogeneity. Let . be a homothety homogeneity manifold which has non-trivial homotethy character, i.e., which admits a diffeomorphism ? so ?*g = λ.g for λ. ≠ 1. In Section 10.1, we show that if . is not VSI, then . is not homogeneous and present other foundational material. In Section 10.2,作者: obligation 時(shí)間: 2025-3-25 12:48 作者: blight 時(shí)間: 2025-3-25 16:29
as a basic reference for people working in affine differential geometry. It also should be accessible to undergraduates interested in affine differential geometry. We are primarily concerned with the study of affine surfaces {which} are locally homogeneous. We discuss affine gradient Ricci solitons作者: garrulous 時(shí)間: 2025-3-25 20:54
https://doi.org/10.1385/1597450243biochemistry; biology; cell; enzymes; proteins; vertebrates作者: ineptitude 時(shí)間: 2025-3-26 02:03 作者: invulnerable 時(shí)間: 2025-3-26 06:54 作者: audiologist 時(shí)間: 2025-3-26 10:25
Histone Deacetylases978-1-59745-024-9Series ISSN 2196-9906 Series E-ISSN 2196-9914 作者: nauseate 時(shí)間: 2025-3-26 14:18 作者: 討好美人 時(shí)間: 2025-3-26 18:29 作者: faddish 時(shí)間: 2025-3-27 00:44 作者: POWER 時(shí)間: 2025-3-27 02:48
eorem are treated. In Chapter 7, material concerning homogeneous spaces and symmetric spaces is presented. Book II concludes in Chapter 8 where the relationship978-3-031-01280-8978-3-031-02408-5Series ISSN 1938-1743 Series E-ISSN 1938-1751 作者: CORD 時(shí)間: 2025-3-27 07:14 作者: 向下 時(shí)間: 2025-3-27 13:03
Structure of the Sir2 Family of NAD+-Dependent Histone/Protein Deacetylaseset their respective cognate substrates. This chapter summarizes the results of the structural analysis of the Sir2 enzymes as well as the implications of these studies for structure-based design of Sir2-specific small-molecule compounds that might modulate Sir2 functions for therapeutic application.作者: 五行打油詩 時(shí)間: 2025-3-27 14:44 作者: chassis 時(shí)間: 2025-3-27 18:23
J. Andrew McKee MD,Tso-Pang Yao PhDving mastered a FL, students become new persons which may have a real impact on their L1 ego. Specifically, under the influence of TL culture different personality traits are subject to change which leads to creating new self-perception and acquiring different verbal/non-verbal skills.作者: 跳脫衣舞的人 時(shí)間: 2025-3-27 22:32
ners come to the language classroom with the experience of their own culture(s) and, through the exposure to a foreign language and its culture(s), hopefully they develop a new kind of sensitivity to linguistic and cultural activities that people perform.作者: Constitution 時(shí)間: 2025-3-28 04:21
Roy A. Frye MD, PhDBerliner Exploring teachers’ thinking. Cassell, London, pp. 60–83, 1987, p. 72) moulding the teacher beliefs about language teaching, learner, and teacher. Borg (Teacher cognition and language education. Continuum Research and Practice, London, 2006, p. 275) draws our attention to the impact of cont作者: 加強(qiáng)防衛(wèi) 時(shí)間: 2025-3-28 07:03 作者: 擴(kuò)大 時(shí)間: 2025-3-28 12:37 作者: 兇猛 時(shí)間: 2025-3-28 15:59
Brian Gabrielli PhDf Lorentzian Walker manifolds. We determine which elements of the family are 0-curvature homogeneous, which are 1-curvature homogeneous, and which are 2-curvature homogeneous; for this family, 2-curvature homogeneity will in fact imply local homogeneity. A similar analysis of homothety curvature hom作者: 萬靈丹 時(shí)間: 2025-3-28 22:50
Paul Kwon,Meier Hsu,Dalia Cohen PhD,Peter Atadja PhDer–Lagrange equations defined by Chern forms which generalize the corresponding Euler–Lagrange equations for the Pfaffian discussed previously. In Section 9.5, we give some examples of . (VSI) manifolds; these are pseudo-Riemannian manifolds all of whose scalar Weyl invariants vanish. We also develo作者: 生命 時(shí)間: 2025-3-29 01:17
ese are the left-invariant affine geometries on ?2. Associating to each Type ???? surface the space of solutions to the quasi-Einstein equation corresponding to the eigenvalue ????=-1$ turns out to be a very powerful technique and plays a central role in our study as it links an analytic invariant w作者: 小口啜飲 時(shí)間: 2025-3-29 04:20
Alejandro Vaquero PhD,Michael Scher PhD,Danny Reinberg PhD作者: Commission 時(shí)間: 2025-3-29 08:48
David Waltregny MD, PhD,Vincent Castronovo MD, PhD作者: 真繁榮 時(shí)間: 2025-3-29 12:59 作者: comely 時(shí)間: 2025-3-29 17:49 作者: Parameter 時(shí)間: 2025-3-29 21:43 作者: Thrombolysis 時(shí)間: 2025-3-30 02:16
Biochemistry of Multiprotein HDAC Complexesother chromatin-related activities. We are starting to understand how a limited number of HDACs can perform such a variety of functions. Here we review all the known HDAC-containing complexes including classes I, II, and III and we summarize the implications of their composition to the function for HDACs in vivo.作者: 多產(chǎn)子 時(shí)間: 2025-3-30 07:21
The Class III Protein Deacetylasest regulate their subcellular localizations and catalytic activity. This review focuses on the diverse sub-cellular distribution, substrate specificity, and cellular functions of sirtuins with particular emphasis on the biology of mammalian sirtuins.作者: modifier 時(shí)間: 2025-3-30 09:53
Cell Cycle Targets of Histone Deacetylase Inhibitorse yet to be absolutely identified. These cell cycle effects are the basis of the antiproliferative activity and tumor cell selectivity of these drugs, properties that potentially make them highly effective anticancer drugs.作者: 使困惑 時(shí)間: 2025-3-30 13:58
Regulation of Muscle Gene Expression by Histone DeacetylasesIn addition, we describe work that established roles for a subset of HDACs as signal integrators that couple cues emanating from the cell surface to muscle-specific genes in the nucleus, and we speculate on the potential to manipulate these regulatory cascades with small molecules as a means to treat cardiac and skeletal myopathies.作者: 確定方向 時(shí)間: 2025-3-30 18:43
The Class IIa Histone Deacetylasest transcriptional repressor yRPD3, whereas class II HDACs are related to yHDA1 and class III HDAs to ySIR2. In this review, we focus on the structure and function of class IIa HDACs. These recently discovered enzymes have been implicated as important regulators of gene expression during cell differentiation and development.作者: Tortuous 時(shí)間: 2025-3-30 22:13
Histone Deacetylases in the Response to Misfolded Proteinsl’s response to misfolded proteins. Using the characterization of HDAC6 as a starting point, in this chapter we review the role of HDACs in the cellular response to misfolded proteins. Specifically, we address how HDACs regulate the formation of aggresomes. We also discuss the relevance of these findings to neurodegenerative disease.
