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標題: Titlebook: Histamine and Histamine Receptors in Health and Disease; Yuichi Hattori,Roland Seifert Book 2017 Springer International Publishing AG 2017 [打印本頁]

作者: 郊區(qū)    時間: 2025-3-21 16:03
書目名稱Histamine and Histamine Receptors in Health and Disease影響因子(影響力)




書目名稱Histamine and Histamine Receptors in Health and Disease影響因子(影響力)學科排名




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書目名稱Histamine and Histamine Receptors in Health and Disease網(wǎng)絡公開度學科排名




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書目名稱Histamine and Histamine Receptors in Health and Disease被引頻次學科排名




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書目名稱Histamine and Histamine Receptors in Health and Disease年度引用學科排名




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書目名稱Histamine and Histamine Receptors in Health and Disease讀者反饋學科排名





作者: 先兆    時間: 2025-3-21 20:24
Book 2017he multidisciplinary nature of the field. While the editors realize that it is almost impossible to cover the field completely within the constraints of a single HEP volume, nonetheless, all important aspects will be covered in one way or the other. An overarching introductory chapter will link the
作者: Bravado    時間: 2025-3-22 00:24

作者: ELUDE    時間: 2025-3-22 04:43
Structural Analysis of the Histamine H1 Receptor, receptors, which are specific for H.R. Docking simulation and biochemical experimentation demonstrated that a carboxyl group on the second-generation antihistamines interacts with the anion-binding site. These results imply that the anion-binding site is a key site for the development of highly selective antihistamine drugs.
作者: 多節(jié)    時間: 2025-3-22 09:03

作者: micronized    時間: 2025-3-22 14:28
0171-2004 ovel way.Includes supplementary material: .Includes supplemeThis ?book provides a comprehensive overview on current histamine and histamine receptor research in context of human health and disease and reflect the multidisciplinary nature of the field. While the editors realize that it is almost impo
作者: 壓迫    時間: 2025-3-22 17:43
Changes in Histidine Decarboxylase, Histamine ,-Methyltransferase and Histamine Receptors in Neuropies, neuroimaging, post-mortem human brain studies and cerebrospinal fluid measurements with data from recent clinical trials on histamine receptor agonists and antagonists, with a view to determining the possible role of the histaminergic system in neuropsychiatric disorders and to pave the way for novel histamine-related therapeutic strategies.
作者: Urea508    時間: 2025-3-22 22:54
https://doi.org/10.1007/978-3-319-58194-1drug development; histamine metabolism; histamine receptors; human diseases; human disease model
作者: OTHER    時間: 2025-3-23 01:38
978-3-319-86344-3Springer International Publishing AG 2017
作者: 大漩渦    時間: 2025-3-23 06:08

作者: 混合,攙雜    時間: 2025-3-23 10:38
Yuichi Hattori,Roland SeifertAuthors will cover hot topics in the field..Update on last HEP volume on histamine published 25 years ago..Unique topics are combined a in novel way.Includes supplementary material: .Includes suppleme
作者: Processes    時間: 2025-3-23 15:47
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/h/image/427223.jpg
作者: Eructation    時間: 2025-3-23 21:03

作者: nonplus    時間: 2025-3-24 00:20
Structural Analysis of the Histamine H1 Receptor,ihistamine. The crystal structure showed that doxepin sits deeply inside the ligand-binding pocket and predominantly interacts with residues highly conserved among other aminergic receptors. This binding mode is considered to result in the low selectivity of the first-generation antihistamines for H
作者: 做事過頭    時間: 2025-3-24 06:10
Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Lrent types of assays or mutagenesis studies. To obtain insights into the histamine receptors on a molecular and structural level, crystal structures have to be determined and molecular modelling studies have to be performed. It is widely accepted to generate homology models of the receptor of intere
作者: 摸索    時間: 2025-3-24 08:30
Pharmacological Characterization of Human Histamine Receptors and Histamine Receptor Mutants in thels, and the use of different species orthologues render it difficult to compare and interpret the published results. Thus, the four human histamine receptor subtypes were analyzed side-by-side in the Sf9 insect cell expression system, using radioligand binding assays as well as functional readouts p
作者: FANG    時間: 2025-3-24 12:14
Histamine Release from Mast Cells and Basophils,other amines (e.g., serotonin), proteases, proteoglycans, cytokines/chemokines, and angiogenic factors and rapidly released upon triggering with a variety of stimuli. Moreover, mast cell and basophil histamine release is regulated by several activating and inhibitory receptors. The engagement of dif
作者: 約會    時間: 2025-3-24 15:07

作者: 內(nèi)疚    時間: 2025-3-24 22:47
Histamine H1 Receptor Gene Expression and Drug Action of Antihistamines,d. Levels of histamine H. receptor mRNA and IL-4 mRNA in nasal mucosa were elevated by the provocation of nasal hypersensitivity model rats. Pretreatment with antihistamines suppressed the elevation of mRNA levels. Scores of nasal symptoms were correlatively alleviated to the suppression level of mR
作者: Regurgitation    時間: 2025-3-25 02:54
Histamine Clearance Through Polyspecific Transporters in the Brain,nergic neuronal activity. Histamine .-methyltransferase, which is an enzyme in the central nervous system that metabolizes histamine, is localized to the cytosol. This suggests that a histamine transport process is essential to inactivate histamine. Previous reports have shown the importance of astr
作者: 變白    時間: 2025-3-25 04:25
Histidine Decarboxylase Knockout Mice as a Model of the Pathophysiology of Tourette Syndrome and Reabnormalities in neurotransmitter HA to human disease has been slower to emerge. New insight came with the 2010 description of a rare nonsense mutation in the biosynthetic enzyme histidine decarboxylase (.) that was associated with Tourette syndrome (TS) and related conditions in a single family ped
作者: 得體    時間: 2025-3-25 10:16
Histamine Food Poisoning,individual sensitivity and the detoxification activity. Histamine is the only biogenic amine with regulatory limits set by the European Commission in fish and fishery products, because it can lead to a fatal outcome. However, also fermented foods can be involved in outbreaks and sporadic cases of in
作者: 較早    時間: 2025-3-25 14:22
Regulation of the Cardiovascular System by Histamine, the central nervous system. Histamine also exerts a series of actions upon the cardiovascular system but may not normally play a significant role in regulating cardiovascular function. During tissue injury, inflammation, and allergic responses, mast cells (or non-mast cells) within the tissues can
作者: 觀點    時間: 2025-3-25 18:33
Changes in Histidine Decarboxylase, Histamine ,-Methyltransferase and Histamine Receptors in Neurope, resulting in a lack of histamine-related treatment for these disorders. The current chapter tries to combine information obtained from genetic studies, neuroimaging, post-mortem human brain studies and cerebrospinal fluid measurements with data from recent clinical trials on histamine receptor ag
作者: hermitage    時間: 2025-3-25 23:23

作者: 手勢    時間: 2025-3-26 03:02

作者: HEDGE    時間: 2025-3-26 07:38

作者: 抑制    時間: 2025-3-26 11:26
Histamine and Histamine Receptors in Allergic Dermatitis,including chronic allergic contact dermatitis (CACD), and atopic dermatitis (AD). In CACD and AD patients, repeated skin exposure to antigens contributes to the development of chronic eczematous lesions. Repeated application of haptens on mice allows emulation of the development of CACD in humans. F
作者: 有幫助    時間: 2025-3-26 13:10
Role of the Histamine H4-Receptor in Bronchial Asthma,ti-allergic therapies, with the exception of allergic asthma, where they are clinically without effect. The latest identified histamine receptor subtype 4, which is expressed mainly in hematopoietic cells, now provides a reasonable target for new therapeutic strategies inhibiting histamine function.
作者: 新手    時間: 2025-3-26 17:09
Hiroyuki Fukui,Hiroyuki Mizuguchi,Hisao Nemoto,Yoshiaki Kitamura,Yoshiki Kashiwada,Noriaki Takedaichen Bedeutung sich nur auf wenige Jahre zusammendr?ngenden Entwicklungszug durchlaufen. Mit über 10,2 Millionen Versicherter, einer Pr?mieneinnahme von rund 410 Millionen Reichsmark und einer j?hrlichen Schadensleistung von mehr als 310 Millionen Reichsmark. Zahlen, mit denen sie sich an erster St
作者: 拋棄的貨物    時間: 2025-3-26 21:02
Takeo Yoshikawa,Kazuhiko Yanaichrieben.In übersichtlicher Gliederung und straffer Form erschlie?t das vorliegende Werk das gesamte Recht der sozialen Sicherheit, soweit es für den Arzt von Bedeutung ist...Es erl?utert den sozialrechtlichen Inhalt von Grundbegriffen wie Krankheit, Behinderung, Arbeits-, Berufs- und Erwerbsunf?hig
作者: 羊欄    時間: 2025-3-27 03:12

作者: 炸壞    時間: 2025-3-27 06:59

作者: thrombosis    時間: 2025-3-27 12:11

作者: Freeze    時間: 2025-3-27 16:31

作者: creditor    時間: 2025-3-27 19:25

作者: facilitate    時間: 2025-3-27 21:58

作者: 是限制    時間: 2025-3-28 02:34

作者: NAG    時間: 2025-3-28 09:46
Histamine Release from Mast Cells and Basophils,mmune cells is uncovering new roles for histamine (possibly derived from mast cells and basophils) in allergic, inflammatory, and autoimmune disorders. Thus, the in-depth knowledge of mast cell and basophil histamine release and its biologic effects is poised to uncover new therapeutic avenues for a
作者: 流利圓滑    時間: 2025-3-28 13:38

作者: Crater    時間: 2025-3-28 15:56

作者: condemn    時間: 2025-3-28 18:57
Histamine Clearance Through Polyspecific Transporters in the Brain,ely. The three transporters are expressed in the brain, and their regional distribution is different. Recent studies revealed the contribution of OCT3 and PMAT to histamine transport by primary human astrocytes. Several investigations using mice supported the importance of OCT3 for histamine clearan
作者: 取消    時間: 2025-3-29 00:43
Histidine Decarboxylase Knockout Mice as a Model of the Pathophysiology of Tourette Syndrome and ReA) and has confirmed the etiologic, face, and predictive validity of the model. The .-KO model thus serves as a unique platform to probe the pathophysiology of TS and related conditions, and to generate specific hypotheses for subsequent testing in humans. This chapter summarizes the development and
作者: Interlocking    時間: 2025-3-29 05:44
Histamine Food Poisoning,ize the occurrence of histamine. Further studies are necessary to estimate the human exposure and the relationship between the total amount of the biogenic amines ingested with food and health effects.
作者: Ccu106    時間: 2025-3-29 09:54

作者: Morphine    時間: 2025-3-29 14:58
Role of the Histamine H3 Receptor in the Central Nervous System, against the wake-promoting, anticonvulsant and anorectic effect of histamine (via postsynaptic H. receptors) and its procognitive activity (via postsynaptic H. and H. receptors). Indeed, H. agonists and H. inverse agonists elicit essentially the same effects, at least in rodents; these effects are
作者: Recess    時間: 2025-3-29 18:10
Clinical Development of Histamine H4 Receptor Antagonists,wed anti-inflammatory and anti-pruritic activity preclinically. JNJ 39758979 advanced into human clinical studies and showed efficacy in reducing experimental pruritus and in patients with atopic dermatitis. However, development of this compound was terminated due to the occurrence of drug-induced a
作者: restrain    時間: 2025-3-29 23:22
Histamine and Histamine Receptors in Allergic Dermatitis,ls, and induces scratching behavior in CACD. The administration of H1 or H4 receptor antagonists was effective to ameliorate these symptoms in murine CACD models. The combination of H1 and H4 receptor antagonists is a potential therapeutic target for chronic inflammatory skin diseases such as CACD a
作者: faculty    時間: 2025-3-30 03:31

作者: 改變立場    時間: 2025-3-30 06:56

作者: 陶瓷    時間: 2025-3-30 09:10
Federico Monczor,Sabrina Copsel,Natalia Fernandez,Carlos Davio,Carina Shayo
作者: antidepressant    時間: 2025-3-30 15:28
Robin L. Thurmond,Jennifer Venable,Brad Savall,David La,Sandra Snook,Paul J. Dunford,James P. Edward
作者: babble    時間: 2025-3-30 19:39

作者: BROOK    時間: 2025-3-30 21:45

作者: IDEAS    時間: 2025-3-31 02:55

作者: 支形吊燈    時間: 2025-3-31 05:40

作者: 純樸    時間: 2025-3-31 09:45

作者: nitroglycerin    時間: 2025-3-31 16:13

作者: rheumatism    時間: 2025-3-31 20:17
Takeo Yoshikawa,Kazuhiko Yanaimde Materie...Das Werk vermittelt so eine umfassende praxisbezogene Information über alle für die Sozialmedizin bedeutsamen sozialrechtlichen Fragen für jeden in Wissenschaft, Klinik oder Praxis t?tigen Arzt. ..?.978-3-642-62394-3978-3-7985-1960-2




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