標(biāo)題: Titlebook: Histamine Receptors as Drug Targets; Ekaterini Tiligada,Madeleine Ennis Book 2017 Springer Science+Business Media, LLC, part of Springer N [打印本頁(yè)] 作者: Coagulant 時(shí)間: 2025-3-21 18:06
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書目名稱Histamine Receptors as Drug Targets影響因子(影響力)學(xué)科排名
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書目名稱Histamine Receptors as Drug Targets網(wǎng)絡(luò)公開度學(xué)科排名
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書目名稱Histamine Receptors as Drug Targets被引頻次學(xué)科排名
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書目名稱Histamine Receptors as Drug Targets年度引用學(xué)科排名
書目名稱Histamine Receptors as Drug Targets讀者反饋
書目名稱Histamine Receptors as Drug Targets讀者反饋學(xué)科排名
作者: indices 時(shí)間: 2025-3-21 20:33
Evaluation of Histidine Decarboxylase (HDC) Activity and Human Histamine Receptor 3 (H3R) and HDC ms. These are a radiolabeled method for HDC activity measurement and quantitative real-time polymerase chain reaction (qPCR) methods for quantification and transcript analyses of human HDC and histamine receptor type 3 (H.R).作者: 壯觀的游行 時(shí)間: 2025-3-22 01:22 作者: 強(qiáng)行引入 時(shí)間: 2025-3-22 07:02
Assessment of the Efficacy of Histamine Receptor Antagonists in Murine Models of Atopic Dermatitis,titis-like skin lesions (NC/Nga mice) and a protein-induced mouse model of atopic dermatitis (ovalbumin model) and discusses the role of the histamine receptor (HR) H.R and H.R antagonists in these models.作者: animated 時(shí)間: 2025-3-22 12:37
Methodological Approaches to Study Histamine Pharmacology in the Kidney: From Cell Culture and Cellps taken to obtain a suitable model to study histamine pharmacology in renal cells, starting from the cell isolation to the morpho-functional assays. The in vitro system herein reported mostly reflects the in vivo situation as demonstrated by our previously published data.作者: GROG 時(shí)間: 2025-3-22 13:57
Methodological Approaches to Investigate the Effects of Histamine Receptor Targeting Compounds in Pstamine receptor ligands in breast cancer, which could originate advances in novel therapeutics to treat this disease. This chapter also describes the gold standard radiometric techniques to evaluate the activity of histamine metabolizing enzymes in breast cancer specimens.作者: 正式通知 時(shí)間: 2025-3-22 19:38 作者: hedonic 時(shí)間: 2025-3-22 21:58
Ligand-Binding Kinetics on Histamine Receptors,so known as residence time) are thought to be more important predictors of drug in vivo efficacy. This chapter provides the theoretical background on ligand-binding kinetics and several experimental approaches to determine the target residence time of antihistamines on histamine receptors.作者: cataract 時(shí)間: 2025-3-23 01:33
Methods to Study the Molecular Pharmacology of the Histamine H4 Receptor,igands, which can initiate differential efficacies in various GPCR responses. This chapter will provide an overview of commonly applied methods used to elucidate the molecular pharmacological aspects of the H.R from receptor-ligand-binding interactions to downstream gene transcription.作者: 地名表 時(shí)間: 2025-3-23 06:49
Histamine and the Kidney: In Vivo Animal Models,e of histamine and its receptors in renal (patho)-physiology and to validate histamine receptors as new pharmacological targets in renal diseases. Within this chapter a suitable in vivo model to study diabetic nephropathy and some of the most important parameters to monitor the functional and morphological integrity of the kidney are described.作者: RUPT 時(shí)間: 2025-3-23 11:09
1557-2153 rties and the therapeutic exploitation of histamine receptorThis book illustrates the current state-of-the-art in histamine research, with a focus on the appropriate methodologies to investigate the pharmacological properties and the therapeutic exploitation of HRs and their ligands. In addition, th作者: aerobic 時(shí)間: 2025-3-23 17:36 作者: 事情 時(shí)間: 2025-3-23 18:03
Methods in Pharmacology and Toxicologyhttp://image.papertrans.cn/h/image/427220.jpg作者: characteristic 時(shí)間: 2025-3-24 00:18 作者: hemoglobin 時(shí)間: 2025-3-24 04:54 作者: prodrome 時(shí)間: 2025-3-24 07:43
Histamine Receptors as Drug Targets978-1-4939-6843-5Series ISSN 1557-2153 Series E-ISSN 1940-6053 作者: Wallow 時(shí)間: 2025-3-24 13:24 作者: INERT 時(shí)間: 2025-3-24 16:14
Methodologies to Identify and Analyze Genetic Polymorphisms for Human Histamine Receptors,onalized care and treatment is becoming one of the major focal points in research. This chapter will focus on the tools available to assess polymorphisms and genetic variations in the human histamine receptor family. The genetic composition of this receptor family is discussed and explained. Methodo作者: ADORE 時(shí)間: 2025-3-24 22:00 作者: 平常 時(shí)間: 2025-3-24 23:51 作者: coalition 時(shí)間: 2025-3-25 06:17
Histamine H2 Receptor Biased Signaling Methods, Among the wide range of possible events that could be mediated by a receptor (second messenger modulation, dimerization, desensitization, internalization, G protein-dependent signaling, gene regulation, etc), the ligand–receptor complex governs the ultimate downstream signaling event and the final 作者: Expand 時(shí)間: 2025-3-25 08:53
Ligand-Binding Kinetics on Histamine Receptors,sed predictions concerning competitive antagonism on the target will only be accurate if equilibrium binding of both ligands is allowed. Unless equilibrium for ligand binding is obtained really quickly, it is unlikely that equilibrium is established in vivo. Instead, concentrations of (endogenous) l作者: Inclement 時(shí)間: 2025-3-25 15:13 作者: incarcerate 時(shí)間: 2025-3-25 16:36
Chemiluminescence: A Sensitive Method for Detecting the Effects of Histamine Receptor Agonists/Antavading agent. The intruding pathogens are eliminated through the action of released proteases and by production of reactive oxygen species (ROS). Histamine, a biogenic amine with various physiological and pathological effects, is known to modulate the immune response of neutrophils, e.g., it blunts 作者: 強(qiáng)行引入 時(shí)間: 2025-3-25 20:34
Techniques Used in Pharmacological Evaluation of Histamine H4 Receptor Function on Native Human Eosdeal in the determination of the receptors’ function, biochemistry, and molecular signaling pathways. Unfortunately, they do not reflect the real biological situation, as the receptors are artificially introduced to host system and usually expressed in high quantity, not regulated as in native cells作者: Overthrow 時(shí)間: 2025-3-26 01:38 作者: BABY 時(shí)間: 2025-3-26 04:47 作者: Blemish 時(shí)間: 2025-3-26 11:47 作者: 使習(xí)慣于 時(shí)間: 2025-3-26 12:57 作者: beta-carotene 時(shí)間: 2025-3-26 18:44 作者: Axillary 時(shí)間: 2025-3-26 21:01 作者: compose 時(shí)間: 2025-3-27 04:35 作者: 冷淡一切 時(shí)間: 2025-3-27 08:55
Dermatological Indications of Antihistamines, subclasses depending on their tendency to bond with H., H., H., or H. histamine receptors. H. antihistamines are the most commonly used in dermatology for the treatment of urticaria and other pruritic dermatoses.作者: 過(guò)渡時(shí)期 時(shí)間: 2025-3-27 10:04
Histamine Quantification in Human Blood Samples,ts discovery more than a century ago, it has been one of the most studied molecules in biomedical sciences and has provided blockbuster therapeutic drugs for the management of allergies, gastric ulcers, and more recently for narcolepsy. The discovery of the high affinity H. receptor at the turn of t作者: libertine 時(shí)間: 2025-3-27 17:16 作者: PHAG 時(shí)間: 2025-3-27 18:08 作者: fender 時(shí)間: 2025-3-28 01:35
Chemiluminescence: A Sensitive Method for Detecting the Effects of Histamine Receptor Agonists/Antaf tested compounds against distinct ROS may be evaluated. In this chapter, we describe the methods for the evaluation of ROS modulating effects of histamine agonists/antagonists in human neutrophils by using chemiluminescence methods.作者: 保留 時(shí)間: 2025-3-28 05:42
Techniques Used in Pharmacological Evaluation of Histamine H4 Receptor Function on Native Human Eosary human eosinophils. Methods include: isolation of human eosinophils from peripheral blood, functional determination of the effects of histamine receptors’ ligands (including selective histamine receptor agonists and antagonists), and data elaboration. We believe that the described methods may pla作者: MINT 時(shí)間: 2025-3-28 08:29 作者: coddle 時(shí)間: 2025-3-28 13:05 作者: Nebulous 時(shí)間: 2025-3-28 18:05
Histamine Quantification in Human Blood Samples,tion of the extracted histamine with .-phthalaldehyde (.-PΤ) in an alkaline environment to produce fluorescent condensation derivatives. These are stabilized by acidification commonly 4 min after the addition of .-PΤ and measured using a fluorospectrophotometer at excitation and emission wavelengths作者: 發(fā)怨言 時(shí)間: 2025-3-28 21:06
1557-2153 medical doctors, principle investigators, research scientists, lab directors and technicians, as well as graduate students around the world in pursuing the study of this vital scientific area..978-1-4939-8315-5978-1-4939-6843-5Series ISSN 1557-2153 Series E-ISSN 1940-6053 作者: 橢圓 時(shí)間: 2025-3-29 02:30
Fiona C. Shenton,Natasha Lethbridge,Paul L. Chazot作者: 正論 時(shí)間: 2025-3-29 06:38
Tadeusz Karcz,Urszula Cichoń,Katarzyna Kie?-Kononowicz作者: deface 時(shí)間: 2025-3-29 09:52 作者: 重力 時(shí)間: 2025-3-29 14:14
Reggie Bosma,Tamara A. M. Mocking,Rob Leurs,Henry F. Vischer作者: Minutes 時(shí)間: 2025-3-29 16:54 作者: 不安 時(shí)間: 2025-3-29 23:29
Kristine Ro?bach,Hanna K?chling,Tomoki Fukuyama,Jenny Wilzopolski,Manfred Kietzmann,Wolfgang B?umer作者: antiandrogen 時(shí)間: 2025-3-30 02:14 作者: AORTA 時(shí)間: 2025-3-30 04:12
Alessandro Pini,Eleonora Veglia,Arianna Carolina Rosa作者: Cardioversion 時(shí)間: 2025-3-30 10:32 作者: Mingle 時(shí)間: 2025-3-30 14:35 作者: debris 時(shí)間: 2025-3-30 17:59 作者: 離開可分裂 時(shí)間: 2025-3-30 22:09 作者: 馬賽克 時(shí)間: 2025-3-31 04:03
Book 2017rug discovery researchers, molecular biologists, chemists, toxicologists, lab scientists, medical doctors, principle investigators, research scientists, lab directors and technicians, as well as graduate students around the world in pursuing the study of this vital scientific area..作者: jungle 時(shí)間: 2025-3-31 05:48
E. Berger gallery image. Gallery images are frontal mug shots while probe set consist of low quality CCTV camera images. Face images in gallery and probe sets are first segmented using eye locations and recognition experiments are performed for the different face regions considered. We also study and evaluat作者: 不能根除 時(shí)間: 2025-3-31 12:45 作者: 貪婪的人 時(shí)間: 2025-3-31 17:21
Challenges, Opportunities and Potential Solution Strategies for Environmentally and Socially Responsible Urban Development of Megacities in Africa,ces. The paper discusses challenges related to rapid urbanisation and highlights African distinct differences. Opportunities and potential material and structural solutions are also discussed, along with the associated architectural and socio-economic implications.作者: hermitage 時(shí)間: 2025-3-31 21:33
Harald Nicolai,Martin Schotten,Detlef Muchllein kompetenztheoretischen Diskurs um die Qualit?t von Coachingweiterbildungen perspektivisch zu erweitern und dem Denken in operationalisierbaren und messbaren Kompetenzen ein alternatives Denkmodell an die Seite zu stellen, das von einem komplexen Habitualisierungsprozess ausgeht, der den widers作者: 黃油沒(méi)有 時(shí)間: 2025-4-1 00:41
Hans Kummere, sustainable urban development needs to find a balance between urban expansion and the thermal environment. This chapter proposes a methodology for monitoring and quantifying the growth of urban heat island (UHI) in response to land-use land-cover (LULC) change impacts based on a time series of La作者: Gourmet 時(shí)間: 2025-4-1 04:15
Volger,Laaschactivity. Potential readership includes undergraduate and advanced undergraduate students in Geology and other scientific disciplines, and any moderately- to well-educated people interested in the surrounding world and eager to gain a basic knowledge of the Earth and to reach an integrated view978-3-030-78015-9978-3-030-78013-5
