標(biāo)題: Titlebook: High Throughput Screening; Methods and Protocol William P. Janzen Book 2016Latest edition Springer Science+Business Media New York 2016 hig [打印本頁(yè)] 作者: 變更 時(shí)間: 2025-3-21 18:47
書(shū)目名稱High Throughput Screening影響因子(影響力)
作者: 呼吸 時(shí)間: 2025-3-21 20:39
Design and Implementation of High-Throughput Screening Assays, be made that can greatly impact the outcome of the HTS effort, to the point of making it a success or a failure. Although specific guidelines should be established to ensure that the screening assay reaches an acceptable level of quality, many choices require pragmatism and the ability to compromise opposing forces.作者: 審問(wèn) 時(shí)間: 2025-3-22 02:04 作者: interrupt 時(shí)間: 2025-3-22 05:58
Instrument Quality Control,id dispensers. Two techniques, gravimetric QC and photometric QC, are highlighted in this chapter. When used together, these simple techniques provide a robust process for evaluating liquid handler accuracy and precision, and critically underpin high-quality research programs.作者: GLIDE 時(shí)間: 2025-3-22 09:48
, High-Throughput Screening,cteria to use because of its slow growth and assignment to Biosafety Level-3 by the CDC and NIH. The principles illuminated here, however, are relevant to the execution of most bacteria high-throughput screens.作者: MUT 時(shí)間: 2025-3-22 14:31 作者: Spinal-Fusion 時(shí)間: 2025-3-22 18:53
A Fluorescence-Based High-Throughput Screening Assay to Identify Growth Inhibitors of the Pathogenibrary against the clinically relevant but less frequently screened fungal pathogen .. This enables the user to conduct high-throughput screening using a disease-relevant fungal growth assay and identify novel antifungal chemotypes as drug leads.作者: FIG 時(shí)間: 2025-3-22 21:52
1064-3745 ation advice from the experts.This third edition volumeexpands on the previous editions both by presenting more detailed protocols forthe techniques described in the first and second editions of .High ThroughputScreening: Methods and Protocols.and by covering important new procedures... The first ch作者: 預(yù)定 時(shí)間: 2025-3-23 02:23 作者: 艱苦地移動(dòng) 時(shí)間: 2025-3-23 07:22 作者: organic-matrix 時(shí)間: 2025-3-23 12:38
Application of Imaging-Based Assays in Microplate Formats for High-Content Screening,uisition speed, model system complexity, data management, and analysis systems. This chapter uses an example of screening for genetic factors regulating mitochondrial quality control to exemplify the practical considerations in developing and executing high-content campaigns.作者: Aesthete 時(shí)間: 2025-3-23 15:43
ors are forcing manufacturers and others to produce highly reliable and good quality products and services. This means that reliability and quality principles are now being applied across many diverse sectors of economy and each of these sectors (robotics, health care, power generation, the Internet作者: Vsd168 時(shí)間: 2025-3-23 21:05
David J. Powell,Robert P. Hertzberg,Ricardo Macarr?nach chapter to test reader comprehension.Includes supplement.Billions of dollars are being spent annually world-wide to develop reliable and good quality products and services. Global competition and other factors are forcing manufacturers and others to produce highly reliable and good quality produ作者: Surgeon 時(shí)間: 2025-3-23 22:21 作者: 啞巴 時(shí)間: 2025-3-24 04:36 作者: excursion 時(shí)間: 2025-3-24 08:50 作者: single 時(shí)間: 2025-3-24 13:06 作者: 展覽 時(shí)間: 2025-3-24 15:36
Chatura Jayakody,Emily A. Hull-Ryderopriate for upper-level undergraduate and beginning master’s level students, the text fills a gap in the literature for textbooks on urban planning. Additionally, the book can be used as a reference for planning practitioners and researchers when analyzing quantitative and qualitative data in urban作者: 營(yíng)養(yǎng) 時(shí)間: 2025-3-24 21:11
Peter Drueckesulation and highlights the methodological difficulties of any ex-post regulatory impact analysis. It synthesises theoretical contributions on regulation and describes the regulatory toolbox, with reference to the electricity market. After definitions and a discussion of the rationale of regulation, 作者: molest 時(shí)間: 2025-3-25 00:13 作者: Dri727 時(shí)間: 2025-3-25 06:02
Thomas M. Smith,Daryl L. Richie,Jianshi Taoulation and highlights the methodological difficulties of any ex-post regulatory impact analysis. It synthesises theoretical contributions on regulation and describes the regulatory toolbox, with reference to the electricity market. After definitions and a discussion of the rationale of regulation, 作者: conscience 時(shí)間: 2025-3-25 11:09 作者: 彎彎曲曲 時(shí)間: 2025-3-25 11:54
Alberto di Silvio,JeanFrancois Rolland,Michela Stucchint and the establishment of planning and information systems, in order to deal with the changes in the environment surrounding the production industry in recent years. Some of the major changes have been a diversification of market needs, a shorter delivery period of products, the reduction of the p作者: 擋泥板 時(shí)間: 2025-3-25 16:45
Wensheng Xie,Robert Silvers,Michael Ouellette,Zining Wu,Quinn Lu,Hu Li,Kathleen Gallagher,Kathy Johners on uncertainty analysis and modeling outside their own fThe application areas of uncertainty are numerous and diverse, including all fields of engineering, computer science, systems control and finance. Determining appropriate ways and methods of dealing with uncertainty has been a constant chal作者: Canary 時(shí)間: 2025-3-25 20:36 作者: ARY 時(shí)間: 2025-3-26 03:18 作者: follicular-unit 時(shí)間: 2025-3-26 08:23
Xiu-Lei Mo Ph.D.,Haian Fuers on uncertainty analysis and modeling outside their own fThe application areas of uncertainty are numerous and diverse, including all fields of engineering, computer science, systems control and finance. Determining appropriate ways and methods of dealing with uncertainty has been a constant chal作者: agglomerate 時(shí)間: 2025-3-26 09:08
Adam I. Fogel,Scott E. Martin,Samuel A. Hassoners on uncertainty analysis and modeling outside their own fThe application areas of uncertainty are numerous and diverse, including all fields of engineering, computer science, systems control and finance. Determining appropriate ways and methods of dealing with uncertainty has been a constant chal作者: 吹牛大王 時(shí)間: 2025-3-26 13:45
ermining appropriate ways and methods of dealing with uncertainty has been a constant challenge. The theme for this book is better understanding and the application of uncertainty theories. This book, with invited chapters, deals with the uncertainty phenomena in diverse fields. The book is an outgr作者: blight 時(shí)間: 2025-3-26 19:32
Design and Implementation of High-Throughput Screening Assays,cientists from the disciplines of biology, chemistry, engineering, and informatics. This requires careful consideration of many options and variables, starting with the choice of screening strategy and ending with the discovery of lead compounds. At every step in this process, there are decisions to作者: aspersion 時(shí)間: 2025-3-26 22:25
Characterization of Inhibitor Binding Through Multiple Inhibitor Analysis: A Novel Local Fitting Meing strategies and hit prioritization. Multiple inhibitor experiments, where enzyme inhibition is measured in the presence of two simultaneously varied inhibitors, can provide valuable information about inhibitor binding. These experiments utilize the inhibitor concentration dependence of the observ作者: CURT 時(shí)間: 2025-3-27 02:05 作者: Atheroma 時(shí)間: 2025-3-27 07:16 作者: 輕信 時(shí)間: 2025-3-27 09:36 作者: 案發(fā)地點(diǎn) 時(shí)間: 2025-3-27 15:47
Instrument Quality Control,set of guidelines, and are important components of any laboratory quality assurance program (Popa-Burke et al., J Biomol Screen 14: 1017–1030, 2009). In this chapter, we describe QC procedures useful for monitoring the accuracy and precision of laboratory instrumentation, most notably automated liqu作者: Habituate 時(shí)間: 2025-3-27 18:11
Application of Fluorescence Polarization in HTS Assays,r interactions. This chapter reviews the basic theory of fluorescence polarization, the underlying principle for using fluorescence polarization to study interactions between small-molecule fluorophores and macromolecular targets, and representative applications of fluorescence polarization in high-作者: 交響樂(lè) 時(shí)間: 2025-3-28 00:57 作者: reperfusion 時(shí)間: 2025-3-28 05:00
Screening for Inhibitors of Kinase Autophosphorylation,terest for drug discovery. Using Alk2 as an example, we present two protocols?—?one based on phosphate-binding Alphascreen beads, the other on coupled luminescence measurements of ADP formation?—?that can be used to screen for inhibitors of autophosphorylation.作者: 沒(méi)有貧窮 時(shí)間: 2025-3-28 06:33 作者: 消散 時(shí)間: 2025-3-28 14:05
, High-Throughput Screening,fication of new antibiotics. Here, we discuss our method for screening large compound libraries with virulent ., possibly one of the more difficult bacteria to use because of its slow growth and assignment to Biosafety Level-3 by the CDC and NIH. The principles illuminated here, however, are relevan作者: 投票 時(shí)間: 2025-3-28 18:16 作者: violate 時(shí)間: 2025-3-28 20:36 作者: abduction 時(shí)間: 2025-3-29 01:23 作者: micronutrients 時(shí)間: 2025-3-29 05:10
High-Throughput Cell Toxicity Assays, strategy to find hit and lead compounds for drug discovery projects in the pharmaceutical industry [.], an understanding of the cell toxicity profile of hit molecules from HTS activities is fundamentally important. Recently, there has been a resurgence of interest in phenotypic drug discovery and t作者: 上流社會(huì) 時(shí)間: 2025-3-29 10:14 作者: 泛濫 時(shí)間: 2025-3-29 15:00
Application of Imaging-Based Assays in Microplate Formats for High-Content Screening,ly not measurable by any other method. Collectively referred to as high-content screening (HCS), or high-content analysis (HCA), these methods rely on an expanding array of imaging hardware and software automation. Coupled with an ever-growing amount of diverse chemical matter and functional genomic作者: 冷淡周邊 時(shí)間: 2025-3-29 16:42
Application of Fluorescence Polarization in HTS Assays,r interactions. This chapter reviews the basic theory of fluorescence polarization, the underlying principle for using fluorescence polarization to study interactions between small-molecule fluorophores and macromolecular targets, and representative applications of fluorescence polarization in high-throughput screening.作者: Commission 時(shí)間: 2025-3-29 23:39 作者: CRACK 時(shí)間: 2025-3-30 03:08
https://doi.org/10.1007/978-1-4939-3673-1high throughput screening assays; complex cellular systems; mass spectrometer techniques; drug discover作者: 印第安人 時(shí)間: 2025-3-30 06:35
Protein Kinase Selectivity Profiling Using Microfluid Mobility Shift Assays,Biochemical selectivity profiling is an integral part of early drug development. Typically compounds from optimization phase are regularly tested for off-target activities within or across target families. This article presents workflow and critical aspects of biochemical protein kinase profiling based on microfluidic mobility shift assays.作者: acrophobia 時(shí)間: 2025-3-30 10:14
William P. JanzenIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts作者: flaggy 時(shí)間: 2025-3-30 15:49
Methods in Molecular Biologyhttp://image.papertrans.cn/h/image/426536.jpg作者: 針葉 時(shí)間: 2025-3-30 16:35
978-1-4939-8113-7Springer Science+Business Media New York 2016作者: 首創(chuàng)精神 時(shí)間: 2025-3-31 00:23
High Throughput Screening978-1-4939-3673-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 颶風(fēng) 時(shí)間: 2025-3-31 02:33
Book 2016Latest edition successful .Methods in MolecularBiology .series format, chaptersinclude introductions to their respectivetopics, lists of the necessary materials and reagents, step-by-step, readilyreproducible laboratory protocols, and tips on troubleshooting and avoidingknown pitfalls..Cutting edge and thorough, 作者: 結(jié)束 時(shí)間: 2025-3-31 06:39 作者: 婚姻生活 時(shí)間: 2025-3-31 10:48 作者: DUST 時(shí)間: 2025-3-31 16:50
Mattias Rohman,Jonathan Wingfieldone book that covers both applied reliability and quality; so to gain knowledge of each other‘s specialties, these people had to study various books, articles, or reports on each area. ...As the first book of i978-1-84996-612-2978-1-84628-498-4Series ISSN 1614-7839 Series E-ISSN 2196-999X 作者: 戲法 時(shí)間: 2025-3-31 20:02 作者: 屈尊 時(shí)間: 2025-4-1 01:37 作者: licence 時(shí)間: 2025-4-1 03:02
