作者: PET-scan 時間: 2025-3-21 21:35
978-3-031-40842-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl作者: Engulf 時間: 2025-3-22 03:14
High Performance Computing978-3-031-40843-4Series ISSN 0302-9743 Series E-ISSN 1611-3349 作者: 出價 時間: 2025-3-22 07:01
Lecture Notes in Computer Sciencehttp://image.papertrans.cn/h/image/426307.jpg作者: 殺人 時間: 2025-3-22 11:22 作者: exhibit 時間: 2025-3-22 13:16
Conference proceedings 2023cale on Next-Generation Platforms: Scalable Infrastructures. .First International Workshop on RISC-V for HPC. .Second Combined Workshop on Interactive and Urgent Supercomputing (CWIUS). .HPC on Heterogeneous Hardware (H3)..作者: Fraudulent 時間: 2025-3-22 17:21 作者: DEMUR 時間: 2025-3-22 21:49 作者: 時代錯誤 時間: 2025-3-23 01:27 作者: Optometrist 時間: 2025-3-23 05:32
Alberto Cascajo,Alvaro Arbe,Javier Garcia-Blas,Jesus Carretero,David E. Singh BM (Bonkhoff et al. 1991, 1992). Even highly malignant anaplastic and small cell carcinomas, irradiated and/or hormonally treated tumors, as well as lymphatic or hematogenous mestastases showed distinct BM formations in contact with the stroma (Bonkhoff et al. 1992). These observations suggest a cl作者: MORT 時間: 2025-3-23 10:21 作者: 我怕被刺穿 時間: 2025-3-23 16:44 作者: lanugo 時間: 2025-3-23 18:38 作者: 無法取消 時間: 2025-3-24 00:52
Luca Abenitors of angiogenesis, the involvement of angiogenesis in cancer development and the application of antiangiogenic therapies on established tumors would be discussed. Among various antiangiogenic reagents, special emphasis will be given to antiangiogenic reagents derived from vascular basement membra作者: 傻瓜 時間: 2025-3-24 03:50
Sebastian Oeste,Michael Kluge,Ronny Tschüter,Wolfgang E. NagelA damage response such as BRCA1, the Mre11-Rad50-Nbs1 complex, Claspin, and ATR-interacting protein (ATRIP). All these proteins, which are involved in sensing the damage (ATM, Mre11, Nbs1), in mediating (BRCA1) or transducing (Chk2) the signal, are essential for maintaining genome stability. Notably作者: FORGO 時間: 2025-3-24 07:26
Antony Chazapis,Fotis Nikolaidis,Manolis Marazakis,Angelos Bilasowth arrest as a consequence of telomere shortening or stress is thus the essential feature distinguishing the mortality of normal cells (presumably to provide a barrier against the accumulation of mutations and the formation of cancer) and the immortality of tumor cells.作者: stress-response 時間: 2025-3-24 14:13
Daniel Medeiros,Gabin Schieffer,Jacob Wahlgren,Ivy Pengeptors that facilitate engulfment by phagocytes (Savill et al. 1993). Apoptosis can be caused by a broad range of physiological stimuli or experimentally applied stress conditions, and it appears that cells from all tissue types and from all multi-cellular organisms studied thus far possess this evo作者: Enthralling 時間: 2025-3-24 14:57 作者: Indebted 時間: 2025-3-24 19:24 作者: 斷斷續(xù)續(xù) 時間: 2025-3-25 01:39
Malleable and?Adaptive Ad-Hoc File System for?Data Intensive Workloads in?HPC Applicationsf the different phases by applying malleability techniques to extend or shrink the ad-hoc files system deployment on runtime following application I/O demands. This work presents the design, implementation, and evaluation of malleability techniques into the Hercules distributed ad-hoc in-memory file作者: 看法等 時間: 2025-3-25 04:26 作者: 稱贊 時間: 2025-3-25 10:06 作者: MEET 時間: 2025-3-25 11:40
Event-Driven Chaos Testing for?Containerized Applicationslistic software faults in a controlled manner while the target system runs. Moreover, since our method is based on runtime events, it ensures deterministic fault injection regardless of the specific system or workload involved. We demonstrate the practicality and relevance of . across various applic作者: 激勵 時間: 2025-3-25 16:46 作者: WAIL 時間: 2025-3-25 23:49
Running Kubernetes Workloads on?HPCSingularity/Apptainer as the container runtime. We consider this approach to be practical for deployment in HPC centers, as it requires minimal pre-configuration and retains existing resource management and accounting policies. HPK provides users with an effective way to utilize resources by a combi作者: 痛苦一生 時間: 2025-3-26 03:35 作者: Mechanics 時間: 2025-3-26 06:54
991). This latter process has been well characterized in the prostate, which regresses after castration or administration of antiandrogens (Léger et al. 1988; Rouleau et al. 1990; Tenniswood et al. 1992), resulting in the death of approximately 80% of the epithelial cells (DeKlerk and Coffey 1978; E作者: erythema 時間: 2025-3-26 09:13
Marc-André Vef,Alberto Miranda,Ramon Nou,André Brinkmann 7-dehydrocholesterol is irradiated with ultraviolet light, the bond between carbons 9 and 10 in ring B is broken and ring A rotates through 180° around the single bond between carbons 6 and 7 to form vitamin D. or cholecalciferol (Fig. 1). There are few foodstuffs which contain appreciable amounts 作者: 營養(yǎng) 時間: 2025-3-26 13:49
Alberto Cascajo,Alvaro Arbe,Javier Garcia-Blas,Jesus Carretero,David E. Singhy recently attracted the attention of various research groups. Histologically, the most prominent structure of the ECM in the prostate is the basement membrane (BM). This structure deserves particular attention, since it exhibits unique features in the prostate, not observable in other organs. In th作者: 消毒 時間: 2025-3-26 16:57
Hugo Taboada,Romain Pereira,Julien Jaeger,Jean-Baptiste Besnard immature cells of the T cell lineage begin to express cell surface markers such as CD4 and CD8. Prior to these events, the T cell receptor (TCR) undergoes rearrangements resulting in the potential expression of upwards of 10. different receptors. Therefore, it is important that the immune system ha作者: Affirm 時間: 2025-3-26 21:37
Dominik Huber,Martin Schreiber,Martin Schulzulin diversity, which give rise to antigen binding heterodimers capable of responding to a wide spectrum of MHC-presented peptides. However, in this differentiation process only a small number of cells reach the mature state, as most are deleted by a process called negative selection (von . et al. 1作者: Cantankerous 時間: 2025-3-27 02:24 作者: 陶瓷 時間: 2025-3-27 05:43
Jean-Baptiste Besnard,Ahmad Tarraf,Clément Barthélemy,Alberto Cascajo,Emmanuel Jeannot,Sameer Shende immune response and the onset of opportunistic infections and neoplasms. The mechanism responsible of CD4 T-cell depletion is mainly the induction of apoptosis, which can be activated by HIV through various pathways. In this chapter direct and indirect mechanisms of HIV-induced apoptosis in infecte作者: 清醒 時間: 2025-3-27 12:25 作者: Pcos971 時間: 2025-3-27 14:52
resulting from a reciprocal t(9;22) translocation characterized by the formation of a shortened chromosome, named Philadelphia chromosome (Ph), in which the tyrosine kinase of c-ABL is constitutively activated. This chromosomal translocation generates . fusion genes which can be translated in three 作者: 貧窮地活 時間: 2025-3-27 19:52 作者: 青石板 時間: 2025-3-27 21:58
Jonatan Baumgartner,Christophe Lillo,Sébastien Rumleyof metastasis can be conceptually broken down into a series of sequential steps: acquisition of an invasive phenotype, intravasation, travel through the circulatory system, arrest at a secondary site, and extravasation and colonization at that site. The metastatic cell must be able to escape cell de作者: 健談 時間: 2025-3-28 02:11 作者: ARIA 時間: 2025-3-28 09:20
Vincenzo De Maio,Ivona Brandicdamage response. The phosphorylation of H2AX on Ser 139, named γH2AX, is an early response to the generation of DNA DSBs and extends along megabase-long domains, both sites of the lesion, supporting amplification of signal transduction pathways. In parallel, 53BP1 accumulates on damaged chromatin to作者: hallow 時間: 2025-3-28 11:20
Fotis Nikolaidis,Antony Chazapis,Manolis Marazakis,Angelos Bilass macromolecules and organelles. During the last decade, progress made in our understanding of the molecular controls of autophagy has uncovered the importance of tumor suppressor molecules in the stimulation of autophagy. Downexpression of autophagy is an early event during tumorigenesis. However, 作者: Systemic 時間: 2025-3-28 17:06
unction of DNA-PK is to promote DNA end synapsis and regulate DNA end processing in the nonhomologous end-joining pathway of double-strand break repair. This regulation is mediated in part by DNA-PK-catalyzed phosphorylation of both itself and the Artemis nuclease, which trims heavily damaged ends t作者: OVER 時間: 2025-3-28 21:37
Sebastian Oeste,Michael Kluge,Ronny Tschüter,Wolfgang E. Nagelolet light and ionizing radiations or as a consequence of DNA replication or physiological DNA rearrangements. Cells respond to DNA damage by the coordinated induction of cell-cycle arrest and DNA repair or trigger apoptosis if the damage is too extensive. The DNA damage response is induced by two p作者: 大溝 時間: 2025-3-29 01:21 作者: crutch 時間: 2025-3-29 06:20
Antony Chazapis,Fotis Nikolaidis,Manolis Marazakis,Angelos Bilashat prevent infinite proliferation: replicative senescence and stress-induced senescence (SIS). In replicative senescence, failure of the DNA polymerase to faithfully duplicate the chromosomal ends leads to progressive telomeric DNA sequence loss with each subsequent cell division and signaling for 作者: Decibel 時間: 2025-3-29 08:34
Daniel Medeiros,Gabin Schieffer,Jacob Wahlgren,Ivy Peng It is fundamental to processes as diverse as tissue remodelling during embryogenesis, maintenance of tissue homeostasis in the adult and to both innate and cognate immunity (Ellis et al. 1991; Cohen et al. 1992; Raff 1992; Ameisen et al. 1994; Vaux et al. 1994; Strasser 1995b; Golstein 1997; Jacobs作者: 柱廊 時間: 2025-3-29 13:36 作者: ADOPT 時間: 2025-3-29 17:14
Malleable Techniques and?Resource Scheduling to?Improve Energy Efficiency in?Parallel Applicationson represents a significant percentage of the CO2 emissions that occur each year in the world, therefore, it is crucial to develop energy efficiency techniques in order to reduce the energy consumption in HPC systems. In this work, we present a resource scheduler capable of choosing, using real-time作者: happiness 時間: 2025-3-29 23:21
Towards Achieving Transparent Malleability Thanks to?MPI Process Virtualizationese changes, the process of launching programs has remained largely unchanged, even with the rise of hybridization and accelerators. However, there is a need to express more complex deployments for parallel applications to enable more efficient use of these machines. In this paper, we propose a tran作者: 清醒 時間: 2025-3-30 03:55
A Case Study on?PMIx-Usage for?Dynamic Resource Managementesource management is a very active research field, as it is expected to improve several metrics of resource utilization on HPC systems, such as job throughput and energy efficiency..However, dynamic resource management is complex and requires significant changes to various layers of the software st作者: 壓迫 時間: 2025-3-30 07:02 作者: 弄皺 時間: 2025-3-30 08:21
Towards Smarter Schedulers: Molding Jobs into?the?Right Shape via?Monitoring and?Modelingcquire valuable results – outlining the importance of performance modelling and optimization. However, it appears that more than punctual optimization is required for current architectures, with users having to choose between multiple intertwined parallelism possibilities, dedicated accelerators, an作者: 轉(zhuǎn)向 時間: 2025-3-30 16:17 作者: Dorsal-Kyphosis 時間: 2025-3-30 17:01
Improving Live Migration Efficiency in QEMU: A Paravirtualized Approachted, a common practice is to live-migrate the Virtual Machine to a different server. This involves copying all the guest memory over the network, which may take a non-negligible amount of time. In this work, we propose a technique to speed up the migration time by reducing the amount of guest memory作者: Pander 時間: 2025-3-30 23:06
Performance Losses with Virtualization: Comparing Bare Metal to VMs and Containersnce losses caused by all kind of virtualization/containerization configurations..A benchmark suite consisting of tools that stress specific components and then four real applications commonly used in computing centers has been designed. A system to schedule the execution of these benchmarks and to c作者: vocation 時間: 2025-3-31 03:59
Real-Time Unikernels: A First Lookthe previous research focused on the virtualization stack (hypervisor, host Operating System, Virtual Machine scheduling, etc.) and did not investigate the impact of the guest Operating System architecture on real-time performance. This paper is a first step in filling this gap and investigates the 作者: 小卷發(fā) 時間: 2025-3-31 08:28
Accelerating Scientific Applications with the Quantum Edge: A Drug Design Use CaseUs, TPUs, ASICs. However, due to the limitation to scalability of hardware resources posed by the Moore Law, a conspicuous amount of research is focusing in integration of Quantum Computers in the overall computing continuum. The high amount of data and the high heterogeneity of quantum architecture作者: 很像弓] 時間: 2025-3-31 12:54
Event-Driven Chaos Testing for?Containerized Applicationsd systems deal with failures. Existing Chaos tools often lack a comprehensive understanding of the system’s runtime and typically inject faults in a random manner. While random testing approaches are helpful in uncovering “shallow” bugs, testing deep failure paths requires precise and controlled fau作者: monogamy 時間: 2025-3-31 17:22 作者: 宮殿般 時間: 2025-3-31 17:58
Running Kubernetes Workloads on?HPChow it manages available resources. The HPC world typically favors Slurm for job scheduling, whereas Cloud deployments rely on Kubernetes to orchestrate container instances across nodes. Running hybrid workloads is possible by using bridging mechanisms that submit jobs from one environment to the ot
