標(biāo)題: Titlebook: High Content Screening; A Powerful Approach Paul A. Johnston,Oscar J. Trask Book 2018Latest edition Springer Science+Business Media LLC 20 [打印本頁] 作者: 和尚吃肉片 時(shí)間: 2025-3-21 18:46
書目名稱High Content Screening影響因子(影響力)
作者: CBC471 時(shí)間: 2025-3-21 21:39
Book 2018Latest editionoratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Authoritative and practical, .High Content Screening and Analysis-The Ideal Format for Phenotypic Screening: A Powerful Approach to Systems Cell Biology and Drug Discovery, Second Edition. aims to ensure successful results in the further study of this vital field..作者: Aspirin 時(shí)間: 2025-3-22 01:34
ily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls..Authoritative and practical, .Antigen Processing: Methods and Protocols .is designed for beginners and experts interested in studying antigen processing..作者: 逃避現(xiàn)實(shí) 時(shí)間: 2025-3-22 07:58
ily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls..Authoritative and practical, .Antigen Processing: Methods and Protocols .is designed for beginners and experts interested in studying antigen processing..作者: 神經(jīng) 時(shí)間: 2025-3-22 11:53 作者: 驕傲 時(shí)間: 2025-3-22 16:21
Bhaskar S. Mandavilli,Robert J. Aggeler,Kevin M. Chambersily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls..Authoritative and practical, .Antigen Processing: Methods and Protocols .is designed for beginners and experts interested in studying antigen processing..作者: indicate 時(shí)間: 2025-3-22 18:58
Bhaskar S. Mandavilli,Michelle Yan,Scott Clarkeily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls..Authoritative and practical, .Antigen Processing: Methods and Protocols .is designed for beginners and experts interested in studying antigen processing..作者: Ferritin 時(shí)間: 2025-3-22 21:22 作者: Adulate 時(shí)間: 2025-3-23 02:42 作者: dilute 時(shí)間: 2025-3-23 07:07
Oscar J. Traskily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls..Authoritative and practical, .Antigen Processing: Methods and Protocols .is designed for beginners and experts interested in studying antigen processing..作者: Kidney-Failure 時(shí)間: 2025-3-23 12:21 作者: Expand 時(shí)間: 2025-3-23 14:04
Yun Hua,Daniel P. Camarco,Christopher J. Strock,Paul A. Johnston Ph.D.an inbred strain or of a species. The idiotypes, as antigenic markers, can elicit a humoral or cellular immune response not only in xenogeneic or allogeneic animals, but also in syngeneic or even autologous systems.作者: CURB 時(shí)間: 2025-3-23 20:23 作者: intricacy 時(shí)間: 2025-3-24 02:00
General Staining and Segmentation Procedures for High Content Imaging and Analysishis chapter, we describe standard procedures for labeling and image segmentation in both live and fixed cell samples. The chapter will also provide troubleshooting guidelines for some of the common problems associated with these aspects of HCI.作者: 雄辯 時(shí)間: 2025-3-24 05:49 作者: 貧窮地活 時(shí)間: 2025-3-24 06:38 作者: 航海太平洋 時(shí)間: 2025-3-24 11:20
David Novo Ph.D.,Kaya Ghosh Ph.D.,Sean Burke M.Sc.istinct from the PO and WA groups (Agnello, 1980). The rheumatoid factors (RF) in this group are unique in that in addition to reactivity with an antigen on IgG they cross react with an antigen on DNA-nucleoprotein.作者: 引水渠 時(shí)間: 2025-3-24 16:42
Tools to Measure Autophagy Using High Content Imaging and Analysise autophagy through monitoring the spatial and temporal recruitment both of autophagosomal markers and cargo to the autophagosome. In this section, we will discuss the use of high content imaging (HCI) and analysis in the study of autophagy with reference to commonly used markers of autophagosomal formation.作者: 頂點(diǎn) 時(shí)間: 2025-3-24 19:28
Quality Control for High-Throughput Imaging Experiments Using Machine Learning in Cellprofiler describe an automated quality control protocol implemented in validated open-source software, leveraging the suite of image-based measurements generated by CellProfiler and the machine-learning functionality of CellProfiler Analyst.作者: Trabeculoplasty 時(shí)間: 2025-3-25 01:46
Strategies and Solutions to Maintain and Retain Data from High Content Imaging, Analysis, and Screenation. An HCS data management and analysis infrastructure shared by several research groups can allow efficient use of existing IT resources and ensures company-wide standards for data quality and result generation. This chapter outlines typical HCS workflows and presents IT infrastructure requirements for multi-well plate-based HCS.作者: venous-leak 時(shí)間: 2025-3-25 07:10
1064-3745 ation advice from the expertsThis second edition details some of the recent trends in HCS/HCA/HCI.? New and updated chapters guide readers through methods that utilize reagents and kits that have been developed to measure cells and subpopulation classifications, control measures, overviews of the da作者: 打火石 時(shí)間: 2025-3-25 09:11
K. Kozak,B. Rinn,O. Leven,M. Emmenlauerare the current screening procedures for breast cancer. There are no tumor markers or other laboratory tests that are useful in this regard. The mortality rate from breast cancer in women who avail themselves of screening programs is 50% lower at 5 years than women who have not been screened..作者: seduce 時(shí)間: 2025-3-25 13:01
Judith Wardwell-Swanson,Yanhua Huoglobulins; Type II, which are accounted for by mixed cryoglobulins with a monoclonal component (usually a monoclonal IgM rheumatoid factor and polyclonal IgG); and Type III, consisting of mixed polyclonal cryoglobulins [3, 7].作者: ACME 時(shí)間: 2025-3-25 17:22
Debra Nickischer,Lisa Elkin,Normand Cloutier,Jonathan O’Connell,Martyn Banks,Andrea Westona monoclonal component and occasionally may also contain proteins other than immunoglobulins in the cryoprecipitate. All major immunoglobulin classes as well as Bence Jones proteins have been observed in each of the three types of cryoglobulins.作者: 未開化 時(shí)間: 2025-3-25 23:02
Paul A. Johnston Ph.D.,Malabika Sen,Yun Hua,Daniel P. Camarco,Tong Ying Shun,John S. Lazo,Jennifer R 4] which may be useful as an antigenic stimulus in instances where the original antigen may itself be difficult to obtain or, in some instances, may be infectious in nature [5–7]. In other situations, the internal image may have deleterious effects as will be discussed shortly.作者: Heterodoxy 時(shí)間: 2025-3-26 02:10 作者: watertight, 時(shí)間: 2025-3-26 07:49 作者: Mangle 時(shí)間: 2025-3-26 12:09 作者: chandel 時(shí)間: 2025-3-26 14:38
Applications and Caveats on the Utilization of DNA-Specific Probes in Cell-Based Assays cases this requires the addition of a DNA dye or so-called nuclear counterstain and these have become integral to assay design. End-point assays can use live or fixed cells and thus it is beneficial if such reagents are cell membrane-permeant..Further, membrane-permeant DNA dyes can open new opport作者: 熱心助人 時(shí)間: 2025-3-26 18:06
General Staining and Segmentation Procedures for High Content Imaging and Analysiscause automated image analysis relies heavily on robust demarcation of cells and subcellular regions, reliable methods for labeling cells is a critical component of the HCI workflow. Labeling of cells for image segmentation is typically performed with fluorescent probes that bind DNA for nuclear-bas作者: 才能 時(shí)間: 2025-3-27 01:00 作者: GUISE 時(shí)間: 2025-3-27 02:16 作者: 我就不公正 時(shí)間: 2025-3-27 06:37 作者: Strength 時(shí)間: 2025-3-27 10:19 作者: 自由職業(yè)者 時(shí)間: 2025-3-27 13:59 作者: 慷慨不好 時(shí)間: 2025-3-27 18:54 作者: 反復(fù)無常 時(shí)間: 2025-3-28 01:58 作者: Stable-Angina 時(shí)間: 2025-3-28 05:08
Live-Cell High Content Screening in Drug Developmentalities as screening tools depended on technological breakthroughs in the domain of automated microscopy and automated image analysis. These types of assays are often referred to as high content screening or high content analysis (HCS/HCA). The driving force to adopt imaging for drug development is 作者: morale 時(shí)間: 2025-3-28 07:48 作者: Cupping 時(shí)間: 2025-3-28 13:33
Translocation Biosensors—Versatile Tools to Probe Protein Functions in Living Cells modular protein translocation biosensors tailored to investigate: (1) signal-mediated nucleo-cytoplasmic transport, (2) protease activity, and (3) protein-protein interactions. Besides the mapping of protein function, the biosensors are also applicable to identify chemicals and/or (nano) materials 作者: Dignant 時(shí)間: 2025-3-28 14:43
High Content Positional Biosensor Assay to Screen for Compounds that Prevent or Disrupt Androgen Recf castration resistant prostate cancer (CRPC). This chapter describes the implementation of an AR-TIF2 protein-protein interaction (PPI) biosensor assay to screen for small molecules that can induce AR-TIF2 PPIs, inhibit the DHT-induced formation of AR-TIF2 PPIs, or disrupt pre-existing AR-TIF2 PPIs作者: Talkative 時(shí)間: 2025-3-28 19:12
High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lciated Janus kinase (JAK) phosphorylates STAT3 at Y705. pSTAT3-Y705 dimers traffic into the nucleus and bind to specific DNA response elements in the promoters of target genes to regulate their transcription. However, IL-6 receptor activation induces the phosphorylation of both the Y705 and S727 res作者: 我沒有命令 時(shí)間: 2025-3-29 01:17 作者: 不持續(xù)就爆 時(shí)間: 2025-3-29 07:02
Utilization of Multidimensional Data in the Analysis of Ultra-High-Throughput High Content Phenotypiion provided by these screens, a combination of traditional as well as nontraditional hit identification and prioritization strategies is required. Here, we describe the workflow and analytics of multidimensional high content data to differentiate, group, and prioritize hits.作者: Thrombolysis 時(shí)間: 2025-3-29 09:04
.Antigen Processing: Methods and Protocols., expert researchers in the field provide a comprehensive set of protocols for studying presentation of antigens produced in the standard processing pathways for MHC class I and class II molecules. The chapters follow chronology of intracellular processing作者: IRATE 時(shí)間: 2025-3-29 12:42 作者: Omniscient 時(shí)間: 2025-3-29 17:29
Roy Edwardal for reproducible results.Contains key notes and implement.Antigen processing is a biological process that prepares antigens for the presentation to special cells in the immune system called T lymphocytes. In .Antigen Processing: Methods and Protocols., expert researchers in the field provide a co作者: acrophobia 時(shí)間: 2025-3-29 22:04 作者: 有特色 時(shí)間: 2025-3-30 01:30 作者: cultivated 時(shí)間: 2025-3-30 05:43 作者: Arteriography 時(shí)間: 2025-3-30 08:24
Nick J. Dolman,Brent A. Samson,Kevin M. Chambers,Michael S. Janes,Bhaskar S. Mandavilli .Antigen Processing: Methods and Protocols., expert researchers in the field provide a comprehensive set of protocols for studying presentation of antigens produced in the standard processing pathways for MHC class I and class II molecules. The chapters follow chronology of intracellular processing作者: 污點(diǎn) 時(shí)間: 2025-3-30 14:31
.Antigen Processing: Methods and Protocols., expert researchers in the field provide a comprehensive set of protocols for studying presentation of antigens produced in the standard processing pathways for MHC class I and class II molecules. The chapters follow chronology of intracellular processing作者: 迫擊炮 時(shí)間: 2025-3-30 19:59
Oscar J. Trask .Antigen Processing: Methods and Protocols., expert researchers in the field provide a comprehensive set of protocols for studying presentation of antigens produced in the standard processing pathways for MHC class I and class II molecules. The chapters follow chronology of intracellular processing作者: 逢迎春日 時(shí)間: 2025-3-30 22:35 作者: foppish 時(shí)間: 2025-3-31 01:31
Steven A. Haneyric rings stacked to form a hollow cylinder (length 16-20 nm, diameter 11-12 nm). The outer two rings are composed of α-subunits, while β-subunits, which contain the active sites, comprise the inner two rings. Proteasomes from archaebacteria contain only one type each of α- and β-subunits. Eukaryoti作者: inconceivable 時(shí)間: 2025-3-31 07:32
