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標(biāo)題: Titlebook: Heat Shock Proteins: Potent Mediators of Inflammation and Immunity; Alexzander A. A. Asea,Antonio De Maio Book 2007 Springer Science+Busin [打印本頁]

作者: legerdemain    時(shí)間: 2025-3-21 16:30
書目名稱Heat Shock Proteins: Potent Mediators of Inflammation and Immunity影響因子(影響力)




書目名稱Heat Shock Proteins: Potent Mediators of Inflammation and Immunity影響因子(影響力)學(xué)科排名




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書目名稱Heat Shock Proteins: Potent Mediators of Inflammation and Immunity讀者反饋學(xué)科排名





作者: 蹣跚    時(shí)間: 2025-3-21 23:14

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Angela Wahl,Oriana Hawkins,Curtis Mcmurtrey,Heather Hickman-Miller,Jon Weidanz,William Hildebrandinnovation teams. It is essential to bring about diverse individual interactions, offer open working spaces, and use the output of the emerging interactions to gain competitive advantages. In this world, communication will be at the very heart of your workplace..You will now quit the organizational
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Hsp70 Peptide Acting as a Danger Signal for Natural Killer (NK) Cellsety of an adoptive transfer of IL-2/TKD-activated NK cells was tested in a clinical phase I trial in patients with progressive tumor diseases which were refractory to standard therapy. Apart from an excellent safety profile, the cytolytic activity of patient-derived NK cells could be stimulated in 1
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作者: Intellectual    時(shí)間: 2025-3-22 15:36
The Inside Story: Anti-Inflammatory roles of HSF1 and heat shock proteinsnt inflammatory factor NF-kB. Reciprocal effects are observed on activation of the APR which leads to inhibition of HSF1 through stimulation of inactivating phosphorylation events involving the mitogen activated kinase (MAPK) pathways. Activation of the HSR thus constitutes a feedback regulatory mec
作者: Wernickes-area    時(shí)間: 2025-3-22 18:43
Interaction of Heat Shock Protein 60 with Innate Immune Cellscharacterized. In a cell-type-specific manner, the region aa481–500 and the regions aa241–260, aa391–410 and aa461–480 were identified to account for Hsp60-binding to innate immune cells. A completely different region of Hsp60, aa354–365 was found to be involved in specific LPS-binding, thereby medi
作者: Sarcoma    時(shí)間: 2025-3-23 00:21
Extracellular Functions for an Intracellular Protein: GRP94/GP96 Interactions with the Mammalian Imm function in tumor immunity remains controversial; nonetheless, these activities identify potential clinical roles for GRP94/gp96 as a cancer immunotherapeutic and potential physiological roles of the protein as a “danger” signal/biological adjuvant. The endogenous cellular function of GRP94/gp96, a
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1877-1246 iology (plant and mammal), Biochemistry (pro- and eukaryotic), Immunology, Microbiology, Exercise Medicine, Physiology, Inflammatory diseases, Autoimmunity, Pharmacology and Pathology..978-90-481-7401-0978-1-4020-5585-0Series ISSN 1877-1246 Series E-ISSN 1877-1254
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Release of Heat Shock Proteins: Passive Versus Active Release Mechanismsen harnessed to generate a number of important clinical trails. However, one intriguing question that remains to be answered is how heat shock proteins (HSP) which do not have peptide leader sequence targeting secretion can gain access to the extracellular milieu. This chapter will discuss the most
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作者: 憂傷    時(shí)間: 2025-3-24 09:30
Mechanisms of Stress-Induced Cellular Hsp72 Releaserom stressful conditions. While the critical intracellular roles of heat shock proteins are undisputed, evidence suggests that the cell possess the necessary machinery to actively secrete specific heat shock proteins both basally and in response to cellular stress. This chapter will discuss the secr
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Heat Shock Proteins and Scavenger Receptorsing and prevent the aggregation of proteins. Tumor-derived HSP., released by dying cells or purified from tumor cells, induce protective anti-tumoral immune responses. This property of HSP. is related to their ability to chaperone tumor-derived peptides and to be internalized, in a receptor-dependen
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HSP-APC Interactions: Initiation of Immune Responsesurs through surface receptors on the APC such as CD91. Other molecules such as CD40, LOX-1, CD36, Toll-like receptor-2 & 4, SR-A and SREC-I have also been proposed to be HSP receptors and are discussed. The physiological situations where the HSP-APC interaction is necessary such as cross-priming of
作者: 奇怪    時(shí)間: 2025-3-25 13:22
Extracellular Functions for an Intracellular Protein: GRP94/GP96 Interactions with the Mammalian Imm tumor progression. Extending from early studies into the identity(s) of tumor-specific antigens, the landmark discovery of an immunogenic function for GRP94/gp96 prompted the hypothesis that GRP94/gp96 functions as a cross-presentation antigen and, by virtue of a peptide binding activity, bears the
作者: 惡名聲    時(shí)間: 2025-3-25 16:43
Hsp-Induced Stimulation of Immune Responses class I. Maturation of DC is stimulated by HSP, upregulating the costimulatory molecules CD40, CD80 and CD86, as well as MHC class II, all of which enhance immune responses. The state of maturity of DC may be significant in the balance between immunity and tolerance. Innate immunity is elicited by
作者: 過多    時(shí)間: 2025-3-25 20:02
The Role of Heat Shock Proteins in the Elicitation of Immune Responsesresponses. The exact manner in which they do so, their physiological role in this process, and their distinct ability to promote adaptive immune response is the subject of this chapter. The first part of the chapter will deal with the general known antigenic stimulation properties of heat shock prot
作者: 露天歷史劇    時(shí)間: 2025-3-26 02:04
Hsp70 Family Members, Danger Signals and Autoimmunitynditions. Hsp70 proteins are present in pathogens as well as in healthy cells. They can be expressed constitutively or elevated in response to heat or other cellular stress. Immune responses stimulated by Hsp70 family members include triggering of innate inflammatory responses, enhancing antigen pre
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HSP60: A Pleiotropic Immune Signal B cells were observed in almost all inflammatory diseases. Moreover, HSP60 induces pro-inflammatory phenotype in innate immune cells via Toll-like receptors (TLRs). Accordingly, HSP60 has been considered a pro-inflammatory “danger signal”. However, HSP60 have immunoregulatory potential and could ar
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Alexzander A.A. Aseaure development (e.g., establishment of hydroelectric dams, highways, and roads) are reaching even formerly remote areas of the Brazilian Amazon. In this chapter, we provide a general overview of the impacts of large-scale land-use changes on Amazonian mammals using a comprehensive literature review
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Gabriele Multhoffontinental-wide region. In this sense, hunting needs to be understood in its whole complexity, encompassing material factors as well as immaterial attributes of peoples and cultures that use wildlife across Amazonia. Mammal species occur in a variety of hunting profiles and together are the most tar
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Virginia L. Vega,Antonio De Maioecedents were divided along two main lines, each giving direction and justification for the office of Ambassador at Large, if not its expansion in diplomacy. Both were attempts to help alleviate some of the pressures instigated by the changing nature of diplomatic activity, primarily the increased p
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Monika Fleshner,John D. Johnson,Joshua Friedmaneach individual Big Data Analytics (BDA) capability to achieve ambidexterity (i.e. exploration and exploitation capacities), organizational agility, and better performances. Such insights, whether contextualized in the current digital environment (with business evolving toward Industry 4.0), allowed
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Heat Shock Proteinshttp://image.papertrans.cn/h/image/425022.jpg
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John H.H. Williams,Claire Hunter-Lavinity is restored through natural processes. Shifting cultivation frequently is considered primitive and predevelopment, despite the evidence that some native systems may be highly sophisticated ecologically and that in such systems species and rotations are well adapted to local conditions and needs (Denevan et al. 1984).
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