標(biāo)題: Titlebook: Handbook of Copper Pharmacology and Toxicology; Edward J. Massaro Book 2002 Springer Science+Business Media New York 2002 Alzheimer.aquati [打印本頁(yè)] 作者: irritants 時(shí)間: 2025-3-21 19:45
書目名稱Handbook of Copper Pharmacology and Toxicology影響因子(影響力)
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書目名稱Handbook of Copper Pharmacology and Toxicology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Handbook of Copper Pharmacology and Toxicology被引頻次
書目名稱Handbook of Copper Pharmacology and Toxicology被引頻次學(xué)科排名
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書目名稱Handbook of Copper Pharmacology and Toxicology讀者反饋
書目名稱Handbook of Copper Pharmacology and Toxicology讀者反饋學(xué)科排名
作者: 使迷醉 時(shí)間: 2025-3-21 21:13 作者: 寡頭政治 時(shí)間: 2025-3-22 03:28
Suspension and Termination of Construction, humans .. What is so special about this trace element that makes it essential in biology? Copper ions undergo unique chemistry because of their ability to adopt distinct redox states, either oxidized, Cu(II), or reduced, Cu(I). Consequently, Cu ions serve as important catalytic cofactors in redox c作者: 脆弱么 時(shí)間: 2025-3-22 05:57
,The Behavior of Consumers’ Attitudes,rP (prion protein). This molecular transition converts a normal version of the protein (PrP.) into a pathogenic form (PrP.) that constitutes the major component of an unprecedented type of infectious particle (prion) devoid of nucleic acid. Although there is a wealth of information now available abo作者: GROSS 時(shí)間: 2025-3-22 09:03
Understanding Consumer Financial Behavior disease (CJD) remains a disease of very low incidence, accounting for 1 in 10. deaths per annum worldwide. BSE and CJD are examples of prion diseases, fatal neurodegenerative conditions .. Before the BSE epidemic, prion diseases were infamous because the cause could not be linked to a known pathoge作者: 觀點(diǎn) 時(shí)間: 2025-3-22 16:00
Understanding Contemporary Irelanded for the formation of water molecules are transferred from both sides of the mitochondrial inner membranes in eukaryotic cells and of the cell membrane in prokaryotic cells .. The migration of positive and negative charges from the different sides of the membrane produces electric potential across作者: linear 時(shí)間: 2025-3-22 17:18 作者: discord 時(shí)間: 2025-3-22 21:31
https://doi.org/10.1007/978-1-4842-9309-6een uptake and efflux of copper ions determines the amount of cellular copper. In biological systems, copper is effectively sequestered by binding to molecules such as glutathione or metallothionein or by cytoplasmic transport proteins called copper chaperones .. Consequently, free copper ions are v作者: 頭盔 時(shí)間: 2025-3-23 02:14 作者: 啟發(fā) 時(shí)間: 2025-3-23 06:17
Message Authentication Codes (MACs), in 250,000 ., although in some populations it can be as high as 1 in 40,000 .. A less severe form of the disease, occipital horn syndrome (OHS) or X-cutis laxis, resulting from an allelic variant, has also been described. The clinical symptoms of both Menkes disease and OHS are caused by a lack of 作者: flaunt 時(shí)間: 2025-3-23 10:15 作者: 壓倒性勝利 時(shí)間: 2025-3-23 15:25
Cultural Traits in Economic Theory,property of facile electron loss has made these metals indispensable for a wide variety of biochemical reactions. The same redox properties that makes these metals so useful also renders them potentially toxic. Iron and copper can react with oxygen and oxygen metabolites to generate toxic radicals. 作者: CRUC 時(shí)間: 2025-3-23 20:35
Dental Biofilms in Health and Diseasemutase, and dopamine β-monooxygenase. The redox reactions carried out by these enzymes are facilitated by the ability of copper to shuttle between the two oxidation states Cu(I) and Cu(II). Deficiencies of copper can lead to profound effects, because of the reduced activity of these copper-dependent作者: SYN 時(shí)間: 2025-3-23 23:58 作者: patella 時(shí)間: 2025-3-24 03:39 作者: Granular 時(shí)間: 2025-3-24 08:14
Molecular Modeling and Dynamics of Copper Proteins humans .. What is so special about this trace element that makes it essential in biology? Copper ions undergo unique chemistry because of their ability to adopt distinct redox states, either oxidized, Cu(II), or reduced, Cu(I). Consequently, Cu ions serve as important catalytic cofactors in redox c作者: aphasia 時(shí)間: 2025-3-24 11:59
The Prion Protein and CopperrP (prion protein). This molecular transition converts a normal version of the protein (PrP.) into a pathogenic form (PrP.) that constitutes the major component of an unprecedented type of infectious particle (prion) devoid of nucleic acid. Although there is a wealth of information now available abo作者: Handedness 時(shí)間: 2025-3-24 15:55
Prion Protein disease (CJD) remains a disease of very low incidence, accounting for 1 in 10. deaths per annum worldwide. BSE and CJD are examples of prion diseases, fatal neurodegenerative conditions .. Before the BSE epidemic, prion diseases were infamous because the cause could not be linked to a known pathoge作者: POWER 時(shí)間: 2025-3-24 19:37
Cytochrome-, Oxidaseed for the formation of water molecules are transferred from both sides of the mitochondrial inner membranes in eukaryotic cells and of the cell membrane in prokaryotic cells .. The migration of positive and negative charges from the different sides of the membrane produces electric potential across作者: 轎車 時(shí)間: 2025-3-25 02:56
Interaction of Copper-Binding Proteins from ,ved in the translocation of many ions. A conserved Cys-Pro-X (X = C or H) sequence within the transmembrane channel and a variable number of distinct amino-terminal domains define the CPx classification .. The cytoplasmic subdomains of the CPx-ATPases have a MxCxxC or M/HxxMDHS/GxM metal-binding sit作者: Feigned 時(shí)間: 2025-3-25 06:59 作者: 愛(ài)了嗎 時(shí)間: 2025-3-25 08:28 作者: Inferior 時(shí)間: 2025-3-25 12:52 作者: Incorporate 時(shí)間: 2025-3-25 17:09
Intracellular Copper Transport and ATP7B, the Wilson’s Disease Proteinstasis. However, when copper exceeds the cellular needs, it is toxic through the production of highly reactive hydroxyl radicals that have deleterious effects on cellular components, including destabilization of plasma membranes and lysosomal membranes, disturbance of mitochondrial respiration, depl作者: visceral-fat 時(shí)間: 2025-3-25 21:08 作者: defile 時(shí)間: 2025-3-26 01:52
Molecular Basis of Diseases of Copper Homeostasismutase, and dopamine β-monooxygenase. The redox reactions carried out by these enzymes are facilitated by the ability of copper to shuttle between the two oxidation states Cu(I) and Cu(II). Deficiencies of copper can lead to profound effects, because of the reduced activity of these copper-dependent作者: mechanical 時(shí)間: 2025-3-26 05:23 作者: Creditee 時(shí)間: 2025-3-26 12:10 作者: jungle 時(shí)間: 2025-3-26 15:06
Understanding Consumer Financial Behaviore result of conformationally corrupted protein (PrP.) passing from individual to individual. At the far end of this opposition are those who believe that there is a hidden virus that stimulates production of the abnormal prion protein but is the real culprit. At the other end are those who say that 作者: 褻瀆 時(shí)間: 2025-3-26 18:39
Understanding Contemporary Ireland, many articles have been published on its structure and function, isolated from various organisms and tissues, in the last 75 yr or so . since its discovery by Warburg .. Progress in understanding of the reaction mechanism of cytochrome-. oxidase has been accelerated by X-ray structures of the enzy作者: 服從 時(shí)間: 2025-3-26 23:56 作者: 講個(gè)故事逗他 時(shí)間: 2025-3-27 03:10 作者: Pelago 時(shí)間: 2025-3-27 06:58
Dental Biofilms in Health and Disease state. Free copper, particularly Cu(I), can catalyze the formation of the highly reactive hydroxyl radicals that damage many cell components, including membranes, proteins, and nucleic acids .. The toxic effects of copper are demonstrated in another human genetic disorder, Wilson’s disease (WD). Th作者: Etymology 時(shí)間: 2025-3-27 10:41 作者: Flagging 時(shí)間: 2025-3-27 13:58 作者: HEDGE 時(shí)間: 2025-3-27 19:03 作者: 藥物 時(shí)間: 2025-3-27 22:26
Cytochrome-, Oxidase, many articles have been published on its structure and function, isolated from various organisms and tissues, in the last 75 yr or so . since its discovery by Warburg .. Progress in understanding of the reaction mechanism of cytochrome-. oxidase has been accelerated by X-ray structures of the enzy作者: 主講人 時(shí)間: 2025-3-28 04:18 作者: OTHER 時(shí)間: 2025-3-28 08:57
The Identification of Motifs Involved in the Intracellular Trafficking of the Menkes Disease Proteinr is much reduced, and the brain, blood, and liver show decreased levels of copper. However, in many other tissues, there is an increase in copper levels when compared to normal individuals, although there is still a defect in the function of copper-requiring enzymes .. Cultured fibroblasts from pat作者: 漂白 時(shí)間: 2025-3-28 11:57
Molecular Basis of Diseases of Copper Homeostasis state. Free copper, particularly Cu(I), can catalyze the formation of the highly reactive hydroxyl radicals that damage many cell components, including membranes, proteins, and nucleic acids .. The toxic effects of copper are demonstrated in another human genetic disorder, Wilson’s disease (WD). Th作者: 個(gè)人長(zhǎng)篇演說(shuō) 時(shí)間: 2025-3-28 18:15
Book 2002rning the biochemistry of copper in general and its role in health and disease in particular. Drawing on the wealth of new information emerging from the molecular biology revolution, these experts survey the most important research areas of copper pharmacology and toxicology, including copper protei作者: Intractable 時(shí)間: 2025-3-28 21:29
Biochemistry and Molecular Biology of Copper in Mammalsd information may be found in books edited by Linder ., Sarkar ., and Leone and Mercer ., 1996 reviews by Linder . and Linder and Hazegh-Azam ., and more specialized reviews by Harris ., Pena et al. ., Linder et al. ., and others ..作者: Exaggerate 時(shí)間: 2025-3-28 23:49 作者: MITE 時(shí)間: 2025-3-29 03:58
https://doi.org/10.1007/978-3-319-25703-7xidase. Copper also has the potential to cause cellular damage because of its redox properties. To overcome this dichotomy, the cell regulates copper levels and prevents toxicity with overlapping mechanisms: sequestration, export, and inhibition of entry.作者: 不可救藥 時(shí)間: 2025-3-29 10:39
The Prion Protein and Coppergical interest, identifying the function of PrP. is likely to be important in understanding the pathogenesis of prion diseases, as it has been suggested that impairment of this function as a result of conversion to PrP. may explain some features of the disease phenotype.作者: Irksome 時(shí)間: 2025-3-29 13:41 作者: 保守黨 時(shí)間: 2025-3-29 15:49 作者: Kinetic 時(shí)間: 2025-3-29 22:39
Quality Assurance and Quality Control,d information may be found in books edited by Linder ., Sarkar ., and Leone and Mercer ., 1996 reviews by Linder . and Linder and Hazegh-Azam ., and more specialized reviews by Harris ., Pena et al. ., Linder et al. ., and others ..作者: 無(wú)可非議 時(shí)間: 2025-3-30 01:49
Book 2002 variety ofmetabolic diseases, Menkes and Wilson‘s diseases and occipital horn syndrome, as well as the role of copper in Parkinson‘s disease, prion disease, familial amytrophic lateral sclerosis (ALS), and Alzheimer‘s disease.作者: Melatonin 時(shí)間: 2025-3-30 07:43 作者: fender 時(shí)間: 2025-3-30 10:09
https://doi.org/10.1007/978-1-4842-9309-6intestine to extrusion into the bile, followed by a more detailed review of the molecular mechanism involved in copper uptake in mam-malian cells. For comparison, we will also discuss the extensive knowledge about the mechanisms of Cu uptake in the yeast .作者: Saline 時(shí)間: 2025-3-30 15:23
Cultural Traits in Economic Theory,opper in biological fluids. The relationship between these two metals extends beyond their similar chemical and biological properties. Proper copper homeostasis is required for iron transport in eucaryotes; consequently, the metabolism of these two metals is closely entwined.作者: 遺傳 時(shí)間: 2025-3-30 18:58
Copper Uptake in Eukaryotic Cellsintestine to extrusion into the bile, followed by a more detailed review of the molecular mechanism involved in copper uptake in mam-malian cells. For comparison, we will also discuss the extensive knowledge about the mechanisms of Cu uptake in the yeast .作者: Nebulizer 時(shí)間: 2025-3-30 22:14
A Multicopper Oxidase-Based Iron-Transport System in Yeastopper in biological fluids. The relationship between these two metals extends beyond their similar chemical and biological properties. Proper copper homeostasis is required for iron transport in eucaryotes; consequently, the metabolism of these two metals is closely entwined.作者: 偏狂癥 時(shí)間: 2025-3-31 02:48
https://doi.org/10.1057/9781137447074etion of glutathione reserves, and damage of nucleic acids .. To prevent the accumulation of copper to the toxic level, cells are provided regulatory mechanisms that maintain the balance of intracellular copper.作者: 娘娘腔 時(shí)間: 2025-3-31 06:49
Intracellular Copper Transport and ATP7B, the Wilson’s Disease Proteinetion of glutathione reserves, and damage of nucleic acids .. To prevent the accumulation of copper to the toxic level, cells are provided regulatory mechanisms that maintain the balance of intracellular copper.作者: 牲畜欄 時(shí)間: 2025-3-31 11:09
Edward J. MassaroIncludes supplementary material:
