標(biāo)題: Titlebook: Handbook of Chemical Biology of Nucleic Acids; Naoki Sugimoto Living reference work 20220th edition DNA.RNA.Riboswitch.Ribozyme.Quadruple [打印本頁] 作者: 交叉路口 時間: 2025-3-21 19:59
書目名稱Handbook of Chemical Biology of Nucleic Acids影響因子(影響力)
書目名稱Handbook of Chemical Biology of Nucleic Acids影響因子(影響力)學(xué)科排名
書目名稱Handbook of Chemical Biology of Nucleic Acids網(wǎng)絡(luò)公開度
書目名稱Handbook of Chemical Biology of Nucleic Acids網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Handbook of Chemical Biology of Nucleic Acids被引頻次
書目名稱Handbook of Chemical Biology of Nucleic Acids被引頻次學(xué)科排名
書目名稱Handbook of Chemical Biology of Nucleic Acids年度引用
書目名稱Handbook of Chemical Biology of Nucleic Acids年度引用學(xué)科排名
書目名稱Handbook of Chemical Biology of Nucleic Acids讀者反饋
書目名稱Handbook of Chemical Biology of Nucleic Acids讀者反饋學(xué)科排名
作者: 自作多情 時間: 2025-3-21 22:17 作者: Hiatal-Hernia 時間: 2025-3-22 04:16 作者: SPECT 時間: 2025-3-22 07:59 作者: Conscientious 時間: 2025-3-22 10:38
Robin Ivy Osterkamp,Friederike Wünschte gene expression by binding to RNAs, etc. .H NMR experiments allow determination of NOE effects and scalar coupling constants between nearby protons of nucleobases and sugar units. The low proton density of nucleic acids allows for rapid detection and identification of hydrogen bonds, which enable作者: BRACE 時間: 2025-3-22 14:13 作者: ABASH 時間: 2025-3-22 18:12 作者: aphasia 時間: 2025-3-22 22:56 作者: 躲債 時間: 2025-3-23 04:01 作者: Anal-Canal 時間: 2025-3-23 07:48 作者: 真 時間: 2025-3-24 00:11
,Einige zus?tzliche Aphorismen, or by application of a chemoenzymatic method. In this chapter, we will describe how the combination of polymerases and nucleoside triphosphate analogs can be harnessed to synthesize oligonucleotides containing nucleobase modifications. We will highlight the potency of this approach through the desc作者: GIST 時間: 2025-3-24 06:17
Living reference work 20220th editioncids (Section Editor: Prof. Chaoyong Yang), Nanotechnology and Nanomaterial Biology of Nucleic Acids (Section Editor: Prof. Zhen Xi), Nucleic Acids Therapeutics (Section Editor: Prof. Katherine Seley-Radtke), Biotechnology and Synthetic Biology of Nucleic Acids (Section Editor: Prof. Eriks Rozners),作者: 鑲嵌細(xì)工 時間: 2025-3-24 07:25 作者: 乏味 時間: 2025-3-24 11:08 作者: corporate 時間: 2025-3-24 17:33
,Quadruplexes Are Everywhere…On the Other Strand Too: The i-Motif,Last, the interaction between i-motif and ligands and the physiological roles of i-motif are briefly introduced. We argue that the i-motif, similar to its complementary G-quadruplex, is an attractive structure for multidisciplinary approaches. It serves as a basic component for various applications 作者: 大看臺 時間: 2025-3-24 19:58 作者: 女歌星 時間: 2025-3-25 02:21 作者: CLEAR 時間: 2025-3-25 03:39 作者: ESPY 時間: 2025-3-25 10:10 作者: 漂白 時間: 2025-3-25 15:11
Studying Nucleic Acid-Ligand Binding by X-Ray Crystallography,abanks mean that the reliability of the data and final model can be assessed against standard criteria and benchmarks. The data is then in the public domain and can be accessed freely worldwide, an important contribution to international scholarship. In this chapter, we explain these crystallographi作者: 譏笑 時間: 2025-3-25 16:41
Hexitol Nucleic Acid (HNA): From Chemical Design to Functional Genetic Polymer,ctional boundaries of extant biopolymers. Herein, we discuss the more recent progress that has been made to synthesize HNA as well as related six-membered nucleic acids [altritol nucleic acid (ANA), FHNA (3′-fluorohexitol nucleic acid), cyclohexene nucleic acid (CeNA), and 2′-fluoro cyclohexene nucl作者: freight 時間: 2025-3-25 23:35 作者: dagger 時間: 2025-3-26 01:50 作者: Conducive 時間: 2025-3-26 08:19 作者: 過濾 時間: 2025-3-26 10:06 作者: essential-fats 時間: 2025-3-26 13:49 作者: 膽小鬼 時間: 2025-3-26 19:56 作者: irradicable 時間: 2025-3-26 21:31 作者: 兒童 時間: 2025-3-27 04:24 作者: 最高點(diǎn) 時間: 2025-3-27 08:37
y used in various technical applications using nucleic acids. Thermodynamics for the structural changes is highly useful and important for understanding the biological mechanism of nucleic acid function, as well as for the design of materials for nucleic acids. The canonical structure of nucleic aci作者: 轉(zhuǎn)換 時間: 2025-3-27 13:10
ze the canonical and noncanonical DNA structures. Under most solution conditions, double- and triple-stranded DNA molecules are stabilized to a small extent by increasing pressure regardless of their nucleotide sequence. On the other hand, the stabilities of noncanonical conformations, including hai作者: 嗎啡 時間: 2025-3-27 15:21 作者: 使迷惑 時間: 2025-3-27 20:30
Robin Ivy Osterkamp,Friederike Wünschbiochemical studies. Knowledge of the structure and dynamics of nucleic acids is important not only for understanding biological mechanisms, but also for developing new therapeutics. NMR (Nuclear Magnetic Resonance) spectroscopy has been used for many years to determine the structure of nucleic acid作者: GET 時間: 2025-3-28 01:44 作者: 憤慨一下 時間: 2025-3-28 04:44 作者: ROOF 時間: 2025-3-28 08:18
Trans-Cultural Leadership Developmentarea of research in telomere, gene regulation, and functional genomics research. Investigation of G-quadruplex structures associated with biological events is therefore essential to understanding the functions of these molecules. Antibodies and some small molecules have been used to investigate DNA 作者: constitute 時間: 2025-3-28 12:29
Trans-European Energy Networks,raction between them at the atomic level is expected to provide valuable information for revealing the molecular mechanism responsible for the regulation of diverse biological processes through their interaction. Heme binds selectively to the 3’-terminal G-quartet of a parallel G-quadruplex DNA to f作者: 借喻 時間: 2025-3-28 17:03 作者: BANAL 時間: 2025-3-28 19:12 作者: 違法事實(shí) 時間: 2025-3-29 02:04
https://doi.org/10.1007/978-3-211-70975-7herapeutic agents to modulate gene expression or impede protein function by binding a specific RNA sequence or target protein but also in synthetic biology, particularly in the context of artificial genetic polymers (XNAs). In order to enable maximum scope for all . applications, it is pivotal for o作者: ANA 時間: 2025-3-29 04:40
Michael Lützkendorf,Michael Ruhrl?ndercations in structure elucidation, synthetic genetics, and therapeutics, among others. This chapter explores the use of 2′-fluoroarabino nucleic acids (FANA) in the context of noncanonical nucleic acid structures, namely triple helices, G-quadruplexes, and i-motifs. For the last three decades, FANA h作者: transdermal 時間: 2025-3-29 10:15
The Payments Special: Europe Versus the US, nucleosides present enormous opportunities. Here we discuss their fundamental design features, compare and contrast them to other families of fluorescent nucleoside analogs, as well as illustrate their utility and highlight potential limitations. The isomorphic nature of the analogs and their faith作者: Cougar 時間: 2025-3-29 15:11
Transaction Costs and Security Institutionscleotide (ON) molecules play an essential role in managing cellular genetic disorders because of their sequence-specific inhibitory effect on complementary RNAs. ONs with modified nucleosides exhibit higher enzymatic stability, duplex-forming ability, sequence selectivity, and in vivo pharmacokineti作者: BOAST 時間: 2025-3-29 18:36 作者: 不適 時間: 2025-3-29 22:20 作者: indecipherable 時間: 2025-3-30 03:38 作者: 食物 時間: 2025-3-30 06:23
The Office-Adapted Lean Tool System,ch as cyclophosphamide, melphalan, cisplatin, psoralen, and mitomycin C. These molecules are formed by a covalent bond to nucleobases in duplex DNA. In addition, cross-linking of nucleic acid duplexes is used in many fields, such as diagnostics, therapeutics, and many forms of nanotechnology. Thus, 作者: 漂白 時間: 2025-3-30 12:15
,Einige zus?tzliche Aphorismen, have also advanced as pivotal tools in numerous applications such as therapeutic technologies, diagnostics, or material sciences. Chemical modifications, particularly at the level of the nucleobases, are ubiquitous. Indeed, base modifications in natural DNA and RNA are nearly as important as the pr作者: tenosynovitis 時間: 2025-3-30 13:17 作者: Lobotomy 時間: 2025-3-30 20:21
Stability Prediction of Canonical and Noncanonical Structures of Nucleic Acids,y used in various technical applications using nucleic acids. Thermodynamics for the structural changes is highly useful and important for understanding the biological mechanism of nucleic acid function, as well as for the design of materials for nucleic acids. The canonical structure of nucleic aci作者: 誘騙 時間: 2025-3-30 23:47
The Effect of Pressure on the Conformational Stability of DNA,ze the canonical and noncanonical DNA structures. Under most solution conditions, double- and triple-stranded DNA molecules are stabilized to a small extent by increasing pressure regardless of their nucleotide sequence. On the other hand, the stabilities of noncanonical conformations, including hai作者: BOLUS 時間: 2025-3-31 03:34 作者: Vulnerary 時間: 2025-3-31 05:07
NMR Study on Nucleic Acids,biochemical studies. Knowledge of the structure and dynamics of nucleic acids is important not only for understanding biological mechanisms, but also for developing new therapeutics. NMR (Nuclear Magnetic Resonance) spectroscopy has been used for many years to determine the structure of nucleic acid作者: 全神貫注于 時間: 2025-3-31 09:27
Z-DNA,eral Z-DNA-binding proteins and Z-DNA-forming sequences in the genome have confirmed the biological relevance of Z-DNA. Over the last five decades, enormous scientific achievements have been made by outstanding scientists to reveal the chemical nature of Z-DNA and the role of Z-DNA and Z-DNA-binding作者: Moderate 時間: 2025-3-31 15:39 作者: 剛開始 時間: 2025-3-31 19:17
In Cell 19F NMR for G-quadruplex,area of research in telomere, gene regulation, and functional genomics research. Investigation of G-quadruplex structures associated with biological events is therefore essential to understanding the functions of these molecules. Antibodies and some small molecules have been used to investigate DNA 作者: 河流 時間: 2025-4-1 01:29
Structures and Catalytic Activities of Complexes Between Heme and DNA,raction between them at the atomic level is expected to provide valuable information for revealing the molecular mechanism responsible for the regulation of diverse biological processes through their interaction. Heme binds selectively to the 3’-terminal G-quartet of a parallel G-quadruplex DNA to f作者: amyloid 時間: 2025-4-1 03:05
Studying Nucleic Acid-Ligand Binding by X-Ray Crystallography,, this method has provided the fundamental details of nucleic acid structure, starting with the DNA double helix, and now extending to encompass the diversity of both DNA and RNA and their interactions with both small molecules (ligands) and proteins. The technique generates primary structural data 作者: 單色 時間: 2025-4-1 08:03 作者: 牢騷 時間: 2025-4-1 10:55 作者: 使激動 時間: 2025-4-1 16:12 作者: 脫毛 時間: 2025-4-1 20:27 作者: Minatory 時間: 2025-4-1 23:46 作者: Gingivitis 時間: 2025-4-2 05:49 作者: Focus-Words 時間: 2025-4-2 08:17
Chemistry of Cyclic Dinucleotides and Analogs,le, a CDN composed of two guanine bases is called cyclic-di-GMP (c-di-GMP). CDNs are biosynthesized from two nucleoside 5′-triphosphates by cyclase enzymes, such as guanylate cyclase which synthesizes c-di-GMP. Since the 1980s, as the biological significance of CDNs has become clear, chemists have f作者: 奇怪 時間: 2025-4-2 11:57
Labeling and Detection of Modified Nucleic Acids,re than 17 and 160 different types of modified bases that have been discovered in DNA and RNA. The nucleic acid epigenetics were emerged to understand the specific biological functions of these DNA and RNA modifications. For this purpose, the development of detection methods of nucleic acid modifica
