標(biāo)題: Titlebook: Handbook of Chemical Biology of Nucleic Acids; Naoki Sugimoto Reference work 2023 Springer Nature Singapore Pte Ltd. 2023 DNA.RNA.Riboswit [打印本頁] 作者: BULK 時間: 2025-3-21 19:21
書目名稱Handbook of Chemical Biology of Nucleic Acids影響因子(影響力)
書目名稱Handbook of Chemical Biology of Nucleic Acids影響因子(影響力)學(xué)科排名
書目名稱Handbook of Chemical Biology of Nucleic Acids網(wǎng)絡(luò)公開度
書目名稱Handbook of Chemical Biology of Nucleic Acids網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Handbook of Chemical Biology of Nucleic Acids被引頻次
書目名稱Handbook of Chemical Biology of Nucleic Acids被引頻次學(xué)科排名
書目名稱Handbook of Chemical Biology of Nucleic Acids年度引用
書目名稱Handbook of Chemical Biology of Nucleic Acids年度引用學(xué)科排名
書目名稱Handbook of Chemical Biology of Nucleic Acids讀者反饋
書目名稱Handbook of Chemical Biology of Nucleic Acids讀者反饋學(xué)科排名
作者: OATH 時間: 2025-3-21 21:37
Stability Prediction of Canonical and Noncanonical Structures of Nucleic Acidsy used in various technical applications using nucleic acids. Thermodynamics for the structural changes is highly useful and important for understanding the biological mechanism of nucleic acid function, as well as for the design of materials for nucleic acids. The canonical structure of nucleic aci作者: G-spot 時間: 2025-3-22 01:50
The Effect of Pressure on the Conformational Stability of DNAze the canonical and noncanonical DNA structures. Under most solution conditions, double- and triple-stranded DNA molecules are stabilized to a small extent by increasing pressure regardless of their nucleotide sequence. On the other hand, the stabilities of noncanonical conformations, including hai作者: 食品室 時間: 2025-3-22 05:38 作者: linear 時間: 2025-3-22 08:50
i-Motif Nucleic Acidsosine base pairs. In this chapter, we take you through an overview of i-motif nucleic acids: the structure of i-motif DNA, their special relationship with pH, their potential functions in biology, and targeting with ligands and probes.作者: 不如樂死去 時間: 2025-3-22 14:07
NMR Study on Nucleic Acidsbiochemical studies. Knowledge of the structure and dynamics of nucleic acids is important not only for understanding biological mechanisms, but also for developing new therapeutics. NMR (Nuclear Magnetic Resonance) spectroscopy has been used for many years to determine the structure of nucleic acid作者: 通便 時間: 2025-3-22 18:33 作者: Distribution 時間: 2025-3-23 00:08 作者: 軍械庫 時間: 2025-3-23 04:16 作者: Fresco 時間: 2025-3-23 06:50
Structures and Catalytic Activities of Complexes Between Heme and DNAraction between them at the atomic level is expected to provide valuable information for revealing the molecular mechanism responsible for the regulation of diverse biological processes through their interaction. Heme binds selectively to the 3′-terminal G-quartet of a parallel G-quadruplex DNA to f作者: Mnemonics 時間: 2025-3-23 12:32 作者: 巨碩 時間: 2025-3-23 14:59
Predicting the 3D Structure of RNA from Sequencectures that they form are essential for the performance of their functions. Experimentally determining the 3D structure of an RNA molecule is difficult and time consuming, so it is desirable to be able to predict the 3D structure that an RNA molecule will fold into based only on the molecule’s seque作者: 群島 時間: 2025-3-23 18:59
Hexitol Nucleic Acid (HNA): From Chemical Design to Functional Genetic Polymerherapeutic agents to modulate gene expression or impede protein function by binding a specific RNA sequence or target protein but also in synthetic biology, particularly in the context of artificial genetic polymers (XNAs). In order to enable maximum scope for all . applications, it is pivotal for o作者: 都相信我的話 時間: 2025-3-23 22:19
The Effects of FANA Modifications on Non-canonical Nucleic Acid Structurescations in structure elucidation, synthetic genetics, and therapeutics, among others. This chapter explores the use of 2′-fluoroarabino nucleic acids (FANA) in the context of noncanonical nucleic acid structures, namely triple helices, G-quadruplexes, and i-motifs. For the last three decades, FANA h作者: 使激動 時間: 2025-3-24 05:27
Isomorphic Fluorescent Nucleoside Analogs nucleosides present enormous opportunities. Here we discuss their fundamental design features, compare and contrast them to other families of fluorescent nucleoside analogs, as well as illustrate their utility and highlight potential limitations. The isomorphic nature of the analogs and their faith作者: 神化怪物 時間: 2025-3-24 10:34 作者: 使習(xí)慣于 時間: 2025-3-24 14:31 作者: Anticoagulants 時間: 2025-3-24 15:37
https://doi.org/10.5822/978-1-61091-904-3y used in various technical applications using nucleic acids. Thermodynamics for the structural changes is highly useful and important for understanding the biological mechanism of nucleic acid function, as well as for the design of materials for nucleic acids. The canonical structure of nucleic aci作者: GRILL 時間: 2025-3-24 22:51 作者: 同來核對 時間: 2025-3-24 23:53
Traité de nutrition artificielle de l‘a(chǎn)dulteences via hemi-protonated and intercalated C·C. base pairs. Although this structure is favored at acidic pH, recent evidence has demonstrated its existence in vivo, stimulating the exploration of its biological roles. Before that, it was mostly regarded as a mere structural oddity, or a tool for bio作者: 珍奇 時間: 2025-3-25 05:31 作者: Musket 時間: 2025-3-25 09:25
Traité d‘a(chǎn)ndrologie à l‘usage des cliniciensbiochemical studies. Knowledge of the structure and dynamics of nucleic acids is important not only for understanding biological mechanisms, but also for developing new therapeutics. NMR (Nuclear Magnetic Resonance) spectroscopy has been used for many years to determine the structure of nucleic acid作者: cushion 時間: 2025-3-25 14:34
D. Wallon,D. Campion,D. Hannequineral Z-DNA-binding proteins and Z-DNA-forming sequences in the genome have confirmed the biological relevance of Z-DNA. Over the last five decades, enormous scientific achievements have been made by outstanding scientists to reveal the chemical nature of Z-DNA and the role of Z-DNA and Z-DNA-binding作者: 運動的我 時間: 2025-3-25 16:25
https://doi.org/10.1007/978-3-642-49326-3fic human genomic locations of functional significance, such as telomeres, promoters, and replication initiation sites. They are involved in essential cellular processes, such as genome stability, gene transcription, and DNA replication. DNA G-quadruplexes readily form under physiologically relevant作者: 持續(xù) 時間: 2025-3-25 22:34
Siswantari Sijono,Susanto Zuhdiarea of research in telomere, gene regulation, and functional genomics research. Investigation of G-quadruplex structures associated with biological events is therefore essential to understanding the functions of these molecules. Antibodies and some small molecules have been used to investigate DNA 作者: 傲慢物 時間: 2025-3-26 01:00
Trajectory Analysis in Health Careraction between them at the atomic level is expected to provide valuable information for revealing the molecular mechanism responsible for the regulation of diverse biological processes through their interaction. Heme binds selectively to the 3′-terminal G-quartet of a parallel G-quadruplex DNA to f作者: Ancestor 時間: 2025-3-26 07:31 作者: ORBIT 時間: 2025-3-26 11:45 作者: strain 時間: 2025-3-26 16:02
Trakls lyrische Einflüsse und Intertexteherapeutic agents to modulate gene expression or impede protein function by binding a specific RNA sequence or target protein but also in synthetic biology, particularly in the context of artificial genetic polymers (XNAs). In order to enable maximum scope for all . applications, it is pivotal for o作者: sebaceous-gland 時間: 2025-3-26 19:04
,Der Kompromi? im Lichte des Rechts,cations in structure elucidation, synthetic genetics, and therapeutics, among others. This chapter explores the use of 2′-fluoroarabino nucleic acids (FANA) in the context of noncanonical nucleic acid structures, namely triple helices, G-quadruplexes, and i-motifs. For the last three decades, FANA h作者: 疲憊的老馬 時間: 2025-3-27 00:33 作者: Reclaim 時間: 2025-3-27 04:02
https://doi.org/10.1007/978-3-0348-6560-9cleotide (ON) molecules play an essential role in managing cellular genetic disorders because of their sequence-specific inhibitory effect on complementary RNAs. ONs with modified nucleosides exhibit higher enzymatic stability, duplex-forming ability, sequence selectivity, and in vivo pharmacokineti作者: 蜿蜒而流 時間: 2025-3-27 06:15
Naoki SugimotoCommemorates the 70th anniversary of the DNA double helix discovery.Provides comprehensive coverage of fundamentals and applications of nucleic acids.Broadens the reader‘s understanding of nucleic aci作者: constellation 時間: 2025-3-27 11:44
http://image.papertrans.cn/h/image/420962.jpg作者: Insubordinate 時間: 2025-3-27 13:48
Springer Nature Singapore Pte Ltd. 2023作者: 慢慢啃 時間: 2025-3-27 20:22 作者: 量被毀壞 時間: 2025-3-27 23:27 作者: 包租車船 時間: 2025-3-28 04:33
https://doi.org/10.1007/978-981-19-9776-1DNA; RNA; Riboswitch; Ribozyme; Quadruplex; Telomere; Molecular Crowding; Drug Discovery; Genome; DNA Origami作者: Allege 時間: 2025-3-28 08:23 作者: 增強(qiáng) 時間: 2025-3-28 12:09 作者: FECT 時間: 2025-3-28 17:51 作者: 止痛藥 時間: 2025-3-28 21:44 作者: BILE 時間: 2025-3-29 00:24
D. Wallon,D. Campion,D. Hannequin proteins in cells. In this chapter, various chemical biology approaches used to evaluate the physicochemical characteristics and biological roles of Z-DNA/Z-RNA and their binding proteins are comprehensively reviewed. Finally, the clinical implications and perspectives regarding Z-DNA are discussed.作者: BROW 時間: 2025-3-29 04:51
Z-DNA proteins in cells. In this chapter, various chemical biology approaches used to evaluate the physicochemical characteristics and biological roles of Z-DNA/Z-RNA and their binding proteins are comprehensively reviewed. Finally, the clinical implications and perspectives regarding Z-DNA are discussed.作者: Pruritus 時間: 2025-3-29 10:04
Traits of Civilization and Voice DisordersDNA. The pressure sensitivity of a G-quadruplex is attributed to the existence of a void volume in the folded structure and the exposure of central ions to the solvent upon unfolding. For the duplex and G-quadruplex conformations, there are sufficient data to allow the construction of temperature-pressure stability phase diagrams.作者: micturition 時間: 2025-3-29 14:22
,Der Kompromi? im Lichte des Rechts,teractions with thrombin and human telomerase. Despite years of research, novel properties of FANA are still being uncovered today; indeed, FANA promises to consistently serve as an exemplary tool for chemists and molecular biologists investigating nucleic acid phenomena.作者: Fibrinogen 時間: 2025-3-29 15:33
https://doi.org/10.1007/978-3-0348-6560-9r intensified bridged nucleic acids with high enzymatic resistance, sequence specificity, high in vivo efficacy, and low toxicity. Herein, we report numerous promising bridged nucleic acids that have been developed in our laboratory since the introduction of 2′,4′-BNA/LNA.作者: 中國紀(jì)念碑 時間: 2025-3-29 23:05
The Effect of Pressure on the Conformational Stability of DNADNA. The pressure sensitivity of a G-quadruplex is attributed to the existence of a void volume in the folded structure and the exposure of central ions to the solvent upon unfolding. For the duplex and G-quadruplex conformations, there are sufficient data to allow the construction of temperature-pressure stability phase diagrams.作者: cinder 時間: 2025-3-30 01:06 作者: 關(guān)節(jié)炎 時間: 2025-3-30 07:02 作者: 飛鏢 時間: 2025-3-30 09:15
Reference work 2023cids (Section Editor: Prof. Chaoyong Yang), Nanotechnology and Nanomaterial Biology of Nucleic Acids (Section Editor: Prof. Zhen Xi), Nucleic Acids Therapeutics (Section Editor: Prof. Katherine Seley-Radtke), Biotechnology and Synthetic Biology of Nucleic Acids (Section Editor: Prof. Eriks Rozners),作者: HEPA-filter 時間: 2025-3-30 15:14 作者: 四海為家的人 時間: 2025-3-30 17:03
https://doi.org/10.5822/978-1-61091-904-3s solution conditions, especially cellular conditions, as the concentrations of cations and co-solutes in the intracellular condition, termed molecular crowding, vary from those under standard experimental conditions. In addition, the crowding conditions in cells are spatiotemporally variable. Furth作者: 凝視 時間: 2025-3-30 21:43
Traité de nutrition artificielle de l‘a(chǎn)dulteLast, the interaction between i-motif and ligands and the physiological roles of i-motif are briefly introduced. We argue that the i-motif, similar to its complementary G-quadruplex, is an attractive structure for multidisciplinary approaches. It serves as a basic component for various applications 作者: 豐滿有漂亮 時間: 2025-3-31 04:15
Traité d‘a(chǎn)ndrologie à l‘usage des clinicienste gene expression by binding to RNAs, etc. .H NMR experiments allow determination of NOE effects and scalar coupling constants between nearby protons of nucleobases and sugar units. The low proton density of nucleic acids allows for rapid detection and identification of hydrogen bonds, which enable作者: 漫不經(jīng)心 時間: 2025-3-31 06:01 作者: 無能性 時間: 2025-3-31 09:16
Siswantari Sijono,Susanto Zuhdintitatively characterize the thermodynamic properties of the G-quadruplexes. The finding provides new insight into the structural behavior of G-quadruplex in living cells. These results open new avenues for the investigation of G-quadruplex structures in vitro and in living cells.作者: 表示向下 時間: 2025-3-31 14:46
Trajectory Analysis in Health Caree.-OOH) in compound 0, like those of peroxidases such as horseradish peroxidase (HRP), and that the formation of compound I in the complex is promoted by mechanisms that are reminiscent of the “push” and “pull” mechanisms in the catalytic cycle of HRP. These findings allow not only a deeper understa作者: laceration 時間: 2025-3-31 19:19
Uncertainty Quantification for Mars Entryabanks mean that the reliability of the data and final model can be assessed against standard criteria and benchmarks. The data is then in the public domain and can be accessed freely worldwide, an important contribution to international scholarship. In this chapter, we explain these crystallographi作者: GUISE 時間: 2025-4-1 00:16 作者: absolve 時間: 2025-4-1 04:06
https://doi.org/10.1007/978-3-658-16408-9cation for fluorescently monitoring metabolically relevant enzymatic reactions involving nucleobases, nucleosides, cofactors, and oligonucleotides, as well as their utilization for biophysically studying folding and recognition of RNA and DNA oligonucleotides. Focusing on two families of fluorescent作者: crutch 時間: 2025-4-1 06:15
High-Pressure Single-Molecule Studies on Non-canonical Nucleic Acids and Their Interactionss, and the activity of biomolecular systems using pressure perturbation, focusing in particular on non-canonical nucleic acid systems, such as DNA hairpins, G-quadruplexes and i-motifs, and their interactions. Moreover, the effects of cosolutes (salts, osmolytes), macromolecular crowding, and intrin
