標(biāo)題: Titlebook: Handbook of Cancer Vaccines; Michael A. Morse,Timothy M. Clay,H. Kim Lyerly Book 2004 Springer Science+Business Media New York 2004 Antige [打印本頁] 作者: Forbidding 時(shí)間: 2025-3-21 18:15
書目名稱Handbook of Cancer Vaccines影響因子(影響力)
書目名稱Handbook of Cancer Vaccines影響因子(影響力)學(xué)科排名
書目名稱Handbook of Cancer Vaccines網(wǎng)絡(luò)公開度
書目名稱Handbook of Cancer Vaccines網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Handbook of Cancer Vaccines被引頻次
書目名稱Handbook of Cancer Vaccines被引頻次學(xué)科排名
書目名稱Handbook of Cancer Vaccines年度引用
書目名稱Handbook of Cancer Vaccines年度引用學(xué)科排名
書目名稱Handbook of Cancer Vaccines讀者反饋
書目名稱Handbook of Cancer Vaccines讀者反饋學(xué)科排名
作者: lymphoma 時(shí)間: 2025-3-21 22:21 作者: Canvas 時(shí)間: 2025-3-22 04:21 作者: 從容 時(shí)間: 2025-3-22 04:55 作者: 全部逛商店 時(shí)間: 2025-3-22 12:27 作者: 夜晚 時(shí)間: 2025-3-22 13:18
urnet and Lewis Thomas . has been recently highlighted in experiments with gene knockout mice. Compared with wild-type mice, mice lacking sensitivity to either interferon-γ (IFN-γ receptor-deficient mice) or all interferon (IFN) family members (i.e., Stat 1 -deficient mice) developed tumors more rap作者: curriculum 時(shí)間: 2025-3-22 18:11 作者: Surgeon 時(shí)間: 2025-3-22 22:28 作者: 南極 時(shí)間: 2025-3-23 01:29 作者: DEFER 時(shí)間: 2025-3-23 07:17
https://doi.org/10.1057/9780230119819nes. Improved understanding of the molecular basis of antigen recognition has resulted in the development of rationally designed tumor antigen—specific vaccines based on motifs predicted to bind to human class I or class II major histocompatibility complex (MHC) molecules. The use of synthetic pepti作者: Presbycusis 時(shí)間: 2025-3-23 12:03 作者: 浮雕 時(shí)間: 2025-3-23 14:42 作者: 憎惡 時(shí)間: 2025-3-23 22:04
Toward a Future Beyond Employmenthich the presentation of these TAAs to the immune system results in far greater activation of T cells than is being achieved naturally in the host. One approach to create an inflammatory milieu designed to trigger a robust immune response to TAAs involves the use of recombinant viral vectors to deli作者: 符合規(guī)定 時(shí)間: 2025-3-23 22:37
Nikhilesh Dholakia,Romeo V. Turcane vectors are potentially useful in a variety of gene transfer strategies .. Ad vectors are constructed in a manner such that one can insert desired recombinant DNA sequences into the El region of the wildtype Ad genome (Fig. 1). Since the El genes only encompass a small fraction of the Ad genome, a作者: Intruder 時(shí)間: 2025-3-24 04:48 作者: 易碎 時(shí)間: 2025-3-24 09:08
https://doi.org/10.1007/978-1-4613-2991-6ines that stimulate stronger immune responses against pathogenic organisms and cancer. Vaccines composed of genetic material, either DNA or RNA, promise all the benefits of existing vaccines without the risk of infection. Ideal vaccines should be inexpensive, stable, and easy to manufacture and stor作者: 省略 時(shí)間: 2025-3-24 14:35
Toward a New Millennium in Galaxy Morphologytinue to be of interest because they contain a large number of antigens, known and unknown, allowing for both widely applicable as well as patient-specific vaccines. Although the presence of a progressing tumor might suggest that whole-tumor cells would not be immunogenic, mouse experiments performe作者: 歪曲道理 時(shí)間: 2025-3-24 16:05 作者: CULP 時(shí)間: 2025-3-24 20:58 作者: 考博 時(shí)間: 2025-3-25 00:58
Identification of Tumor Antigens Using Subtraction and Microarraysapplication of nucleic acid subtraction methods combined with cDNA microarrays to identify potential tumor antigen candidates. Subtraction techniques form an effective means of enriching for tissue- and tumor-specific genes whereas microarray technology provides us with an efficient high-throughput 作者: 駭人 時(shí)間: 2025-3-25 04:31 作者: crescendo 時(shí)間: 2025-3-25 07:30 作者: Contend 時(shí)間: 2025-3-25 15:41
Immune Defects in Cancerurnet and Lewis Thomas . has been recently highlighted in experiments with gene knockout mice. Compared with wild-type mice, mice lacking sensitivity to either interferon-γ (IFN-γ receptor-deficient mice) or all interferon (IFN) family members (i.e., Stat 1 -deficient mice) developed tumors more rap作者: Deduct 時(shí)間: 2025-3-25 15:54 作者: 財(cái)政 時(shí)間: 2025-3-25 23:16
Immune Adjuvants need for effective delivery strategies and potent adjuvants to induce an appropriate immune response. Although there is evidence that many cancer patients do mount an immune response against their tumor, the affinity and frequency of responding T cells appears to be low. Additionally, the “natural”作者: 山羊 時(shí)間: 2025-3-26 00:58 作者: brachial-plexus 時(shí)間: 2025-3-26 05:54
Peptide-Based Vaccinesnes. Improved understanding of the molecular basis of antigen recognition has resulted in the development of rationally designed tumor antigen—specific vaccines based on motifs predicted to bind to human class I or class II major histocompatibility complex (MHC) molecules. The use of synthetic pepti作者: 他很靈活 時(shí)間: 2025-3-26 12:33
Antibody-Inducing Cancer Vaccines Against Cell-Surface Carbohydrate Antigens the many tumorrestricted monoclonal antibodies derived by immunization of mice with human tumor cells, most have been directed against carbohydrate antigens expressed at the cell surface as glycolipids or mucins .. Antibodies against cell-surface antigens such as these are ideally suited for eradic作者: 挑剔為人 時(shí)間: 2025-3-26 15:52
Anti-Idiotype Vaccines a host antitumor response, in contrast to passive immunotherapy, where large doses of preformed antitumor antibodies, or T cells with predetermined specificity, are infused. In classical ASI, patients are vaccinated with purified tumor-specific or tumor-associated antigens (TAAs). This approach has作者: Magnitude 時(shí)間: 2025-3-26 18:00
Pox Viral Vaccineshich the presentation of these TAAs to the immune system results in far greater activation of T cells than is being achieved naturally in the host. One approach to create an inflammatory milieu designed to trigger a robust immune response to TAAs involves the use of recombinant viral vectors to deli作者: Dappled 時(shí)間: 2025-3-26 21:56 作者: Mri485 時(shí)間: 2025-3-27 03:49 作者: Heresy 時(shí)間: 2025-3-27 08:10
DNA Vaccinesines that stimulate stronger immune responses against pathogenic organisms and cancer. Vaccines composed of genetic material, either DNA or RNA, promise all the benefits of existing vaccines without the risk of infection. Ideal vaccines should be inexpensive, stable, and easy to manufacture and stor作者: VEIL 時(shí)間: 2025-3-27 12:25
Whole-Tumor-Cell Vaccinestinue to be of interest because they contain a large number of antigens, known and unknown, allowing for both widely applicable as well as patient-specific vaccines. Although the presence of a progressing tumor might suggest that whole-tumor cells would not be immunogenic, mouse experiments performe作者: 輕率看法 時(shí)間: 2025-3-27 16:09
Michael A. Morse,Timothy M. Clay,H. Kim LyerlyIncludes supplementary material: 作者: profligate 時(shí)間: 2025-3-27 18:47 作者: 吞吞吐吐 時(shí)間: 2025-3-28 01:37 作者: Cacophonous 時(shí)間: 2025-3-28 05:23 作者: Simulate 時(shí)間: 2025-3-28 09:06
https://doi.org/10.1007/978-1-59259-680-5Antigen; DNA; cancer; cell; clinical trial; cytokine; cytokines; immunotherapy; melanoma; ovarian cancer; pros作者: Additive 時(shí)間: 2025-3-28 13:45 作者: 桉樹 時(shí)間: 2025-3-28 14:57
The Rational Design of T-Cell Epitopes With Enhanced Immunogenicityr-specific immune responses is supported, it remains a significant challenge to design cancer vaccine strategies that consistently overcome immunological tolerance in order to effectively activate and maintain therapeutic T-cell responses. Experimentation in the late 1980s and 1990s has resulted in 作者: 幼兒 時(shí)間: 2025-3-28 22:35
Identification of Tumor Antigens Using Subtraction and Microarrayss such as antibody and T cells from cancer patients. Genes identified via this integrated approach have the advantage of being tumoror tissue-specific and broadly expressed in cancers. Numerous tissue- and tumor-specific genes have been identified in prostate, breast, lung, and colon cancers using t作者: enchant 時(shí)間: 2025-3-28 23:47
Tumor Antigen Discovery With T Cellsge colony-stimulating factor (GM-CSF), or tumor necrosis factor-α (TNF-α) in response to human leukocyte antigen (HLA)-matched tumor targets. Tumor-reactive class II restricted T cells have also been identified in a significant percentage of the cultures of sensitized PBMC or TIL cultures containing作者: GLARE 時(shí)間: 2025-3-29 03:55
Immune Defects in Cancer system .. The correlation between the presence of tumor-infiltrating lymphocytes and survival of patients with melanoma ., breast ., bladder ., colon ., neuroblastoma ., ovary ., and prostate . cancers gives hope that the manipulation of tumor escape mechanisms, by immuntherapeutic interventions, m作者: 煩人 時(shí)間: 2025-3-29 08:30
Escape of Tumors From the Immune Systemr human tumors to escape the immune system. In addition, current evidence supports a model by which this active tumor-mediated immunosuppression is largely the result of secretion of the potent immunosuppressive cytokine, transforming growth factor-? (TGF-?). In this review, the evidence supporting 作者: 發(fā)現(xiàn) 時(shí)間: 2025-3-29 13:19
Peptide-Based Vaccinesimmunization to foreign proteins normally elicits immunity to only a subset of potential epitopes, dominant epitopes, whereas other potentially immunogenic epitopes, subdominant epitopes, are ignored. There is evidence that T cells are tolerant to the dominant epitopes of self-proteins, but may resp作者: 任命 時(shí)間: 2025-3-29 16:17
Antibody-Inducing Cancer Vaccines Against Cell-Surface Carbohydrate Antigenspy is the ideal time for immune intervention, and in particular for administration of cancer vaccines aimed at instructing the immune system to identify and kill these few remaining cancer cells. If antibodies of sufficient titer can be induced against tumor antigens to eliminate tumor cells from th作者: SHOCK 時(shí)間: 2025-3-29 21:59 作者: ascetic 時(shí)間: 2025-3-30 03:10
Pox Viral Vaccinestigen-presenting cells (APCs) allowing them to process the antigens, and c) the relative low cost. The ability to incorporate multiple transgenes within one vector is unique to these large virions, and allows for potential synergy of the incorporated gene products. This chapter will provide some ins作者: Intellectual 時(shí)間: 2025-3-30 07:51
Alphaviral-Based Strategies for the Immunotherapy of Cancersses. Fewer studies have evaluated alphavirus vectors for their antitumor immunotherapy potential and all are preclinical. In contrast, DNA viruses, such as adenovirus or the pox viruses, have progressed to human cancer clinical trials, despite alphavirus vectors having distinct potential advantages作者: dysphagia 時(shí)間: 2025-3-30 10:35 作者: FATAL 時(shí)間: 2025-3-30 13:04
https://doi.org/10.1007/978-981-99-9647-6demonstrated activity in renal cell carcinoma and melanoma. In the past two decades, a new era in cancer immunotherapy has opened with the discovery of how the immune system can recognize and destroy tumors. This has included the description of tumor-expressed antigens that can be recognized by immu作者: 夜晚 時(shí)間: 2025-3-30 19:53 作者: Palpable 時(shí)間: 2025-3-30 23:23
School-Related Inequity Factorss such as antibody and T cells from cancer patients. Genes identified via this integrated approach have the advantage of being tumoror tissue-specific and broadly expressed in cancers. Numerous tissue- and tumor-specific genes have been identified in prostate, breast, lung, and colon cancers using t作者: Definitive 時(shí)間: 2025-3-31 01:06
Toward Integrative Corporate Citizenshipge colony-stimulating factor (GM-CSF), or tumor necrosis factor-α (TNF-α) in response to human leukocyte antigen (HLA)-matched tumor targets. Tumor-reactive class II restricted T cells have also been identified in a significant percentage of the cultures of sensitized PBMC or TIL cultures containing作者: 比喻好 時(shí)間: 2025-3-31 08:56 作者: Friction 時(shí)間: 2025-3-31 10:55
The Necessary Forms of the Knowledger human tumors to escape the immune system. In addition, current evidence supports a model by which this active tumor-mediated immunosuppression is largely the result of secretion of the potent immunosuppressive cytokine, transforming growth factor-? (TGF-?). In this review, the evidence supporting 作者: evanescent 時(shí)間: 2025-3-31 15:00
https://doi.org/10.1057/9780230119819immunization to foreign proteins normally elicits immunity to only a subset of potential epitopes, dominant epitopes, whereas other potentially immunogenic epitopes, subdominant epitopes, are ignored. There is evidence that T cells are tolerant to the dominant epitopes of self-proteins, but may resp作者: 信條 時(shí)間: 2025-3-31 19:56
Improving the Quality of Urbanization,py is the ideal time for immune intervention, and in particular for administration of cancer vaccines aimed at instructing the immune system to identify and kill these few remaining cancer cells. If antibodies of sufficient titer can be induced against tumor antigens to eliminate tumor cells from th作者: Instrumental 時(shí)間: 2025-3-31 23:50 作者: antidepressant 時(shí)間: 2025-4-1 04:51 作者: Lamina 時(shí)間: 2025-4-1 09:36
