標(biāo)題: Titlebook: Handbook of Antimicrobial Resistance; Matthias Gotte (Editor-in-chief),Albert Berghuis,D Reference work 2017 Springer Science+Business Med [打印本頁(yè)] 作者: 斷頭臺(tái) 時(shí)間: 2025-3-21 19:33
書(shū)目名稱Handbook of Antimicrobial Resistance影響因子(影響力)
書(shū)目名稱Handbook of Antimicrobial Resistance影響因子(影響力)學(xué)科排名
書(shū)目名稱Handbook of Antimicrobial Resistance網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Handbook of Antimicrobial Resistance網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Handbook of Antimicrobial Resistance被引頻次
書(shū)目名稱Handbook of Antimicrobial Resistance被引頻次學(xué)科排名
書(shū)目名稱Handbook of Antimicrobial Resistance年度引用
書(shū)目名稱Handbook of Antimicrobial Resistance年度引用學(xué)科排名
書(shū)目名稱Handbook of Antimicrobial Resistance讀者反饋
書(shū)目名稱Handbook of Antimicrobial Resistance讀者反饋學(xué)科排名
作者: 落葉劑 時(shí)間: 2025-3-21 21:41
http://image.papertrans.cn/h/image/420817.jpg作者: 群居男女 時(shí)間: 2025-3-22 04:15 作者: Apoptosis 時(shí)間: 2025-3-22 06:55 作者: 解脫 時(shí)間: 2025-3-22 08:47
Reference work 2017iven a dedicated section. The underlining molecular mechanisms, which depend not only on the microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.?.作者: 后退 時(shí)間: 2025-3-22 13:24 作者: 紀(jì)念 時(shí)間: 2025-3-22 20:51
The European Context of the Wars,ncy against mutational ensemble of quasispecies of the target. The Substrate envelope hypothesis, based on structural studies on the proteases of HIV-1 and hepatitis C, provides a structural basis for the specificity of natural substrate recognition and mechanisms for the resistance mutations in the active site.作者: LURE 時(shí)間: 2025-3-23 00:29
https://doi.org/10.1007/978-1-349-10840-4e of antimicrobial compounds and disinfectants, and the mechanisms underlying this resistance are likely multifactorial. This chapter will review the cellular processes and pathways implicated in antibiotic resistance and tolerance of bacterial biofilms.作者: 混合物 時(shí)間: 2025-3-23 03:09 作者: Vital-Signs 時(shí)間: 2025-3-23 06:11
Protease Inhibitor Resistance to escape from drug pressure with subsequent treatment failure. The emergence of RAVs depends on a number of drug-, host-, and virus-related factors that are reviewed here. In addition, detailed resistance profiles of approved protease inhibitors and those that are still in clinical development are also discussed.作者: MURAL 時(shí)間: 2025-3-23 12:09 作者: 推測(cè) 時(shí)間: 2025-3-23 16:41 作者: 制度 時(shí)間: 2025-3-23 21:38
The Biochemistry of Quinoline Antimalarial Drug Resistance This issue is even more critical for controlling chloroquine-resistant ., about which even less is known. This review summarizes key features of quinoline antimalarial drug resistance in . malaria and suggests concepts relevant for “staying ahead of the resistance curve.”作者: Mercantile 時(shí)間: 2025-3-24 00:57 作者: Gastric 時(shí)間: 2025-3-24 03:29 作者: 微生物 時(shí)間: 2025-3-24 10:35
https://doi.org/10.1007/978-981-97-2504-5n but also in susceptibility to HIV-1 Vif-mediated degradation. The interplay between these intracellular host defenses and HIV counterstrategies is discussed in this chapter with a special emphasis on viral evolution and drug resistance.作者: outskirts 時(shí)間: 2025-3-24 11:03
Michael F. Hopkins,Saul Kelly,John W. Youngmechanisms governing the relationship between the antibacterial and the bacterium. This review examines this relationship from the particular perspective of the eventual need to circumvent resistance mechanisms in order to reclaim the lifesaving value of the antibacterial chemical.作者: FUME 時(shí)間: 2025-3-24 16:47
Contribution of APOBEC3-Driven Mutagenesis to HIV Evolution and HIV Drug Resistancen but also in susceptibility to HIV-1 Vif-mediated degradation. The interplay between these intracellular host defenses and HIV counterstrategies is discussed in this chapter with a special emphasis on viral evolution and drug resistance.作者: –LOUS 時(shí)間: 2025-3-24 21:18
Strategies for Circumventing Bacterial Resistance Mechanismsmechanisms governing the relationship between the antibacterial and the bacterium. This review examines this relationship from the particular perspective of the eventual need to circumvent resistance mechanisms in order to reclaim the lifesaving value of the antibacterial chemical.作者: 單色 時(shí)間: 2025-3-24 23:20
Seif Emseih,Ghassan Soleiman Abu-Sittahdrug resistance is an important clinical concern. In this chapter, we discuss the principles of HBV antiviral resistance and clinical pathways for preventing the selection of drug-resistant variants, as well as appropriate management strategies for antiviral treatment failure.作者: 支形吊燈 時(shí)間: 2025-3-25 05:57
https://doi.org/10.1057/9781403978264esistance are discussed, with specific examples for human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Prospects for new antiviral designs aimed at counteracting the adaptive potential of viral quasispecies are presented.作者: 小平面 時(shí)間: 2025-3-25 07:37
The Church and the Wars of the Roses, 66:401–410, 2013). However, bacteria have gained resistance mechanisms to overcome all major classes of β-lactam antibiotics to date. In this chapter, we will address the major mechanisms of bacterial resistance to the β-lactams and highlight some of the recent advances in circumventing this resistance.作者: Collar 時(shí)間: 2025-3-25 13:18 作者: GLUT 時(shí)間: 2025-3-25 17:14
https://doi.org/10.1007/978-3-031-50962-9e fungal biofilm matrix. We also highlight key matrix components, including β-1,3 glucan and extracellular DNA, which have been specifically shown to be instrumental for production the biofilm drug-resistant phenotype.作者: implore 時(shí)間: 2025-3-25 23:02 作者: minion 時(shí)間: 2025-3-26 03:21
Quasispecies and Drug Resistanceesistance are discussed, with specific examples for human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Prospects for new antiviral designs aimed at counteracting the adaptive potential of viral quasispecies are presented.作者: 胖人手藝好 時(shí)間: 2025-3-26 07:09 作者: 與野獸博斗者 時(shí)間: 2025-3-26 10:52
Drug Resistance in ,ly endemic areas including amphotericin B, paromomycin, and miltefosine. This chapter is presenting our current understanding of the mode of action and underlying resistance mechanisms of the few therapeutic drugs used against ..作者: inflame 時(shí)間: 2025-3-26 16:27 作者: 遺傳 時(shí)間: 2025-3-26 17:07
he microbe, but on the specific drug (target), are highly diverse, and are covered in great detail. This work also discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.?.978-1-4939-0694-9作者: 換話題 時(shí)間: 2025-3-26 21:48
HBV Therapy and the Problem of Drug Resistancee risk of liver disease progression, including cirrhosis, hepatic failure, and hepatocellular carcinoma. Nucleos(t)ide analogue monotherapy is commonly used as first-line therapy, and most patients will require long-term antiviral therapy. As for all direct-acting antiviral agents, the emergence of 作者: 粗糙濫制 時(shí)間: 2025-3-27 02:05
Protease Inhibitor ResistanceV infection, allowing for viral elimination in the majority of treated patients. The first two drugs to be approved for the treatment of HCV genotype 1 infection were the HCV NS3/4A protease inhibitors telaprevir and boceprevir. However, their administration in combination with pegylated interferon 作者: Communal 時(shí)間: 2025-3-27 08:27 作者: 法律 時(shí)間: 2025-3-27 09:55
Resistance to Cyclophilin Inhibitorst accomplished by combining several drugs with potent antiviral activity across multiple genotypes, with each possessing a high barrier to resistance, different mechanisms of action, and no cross-resistance. A novel class of anti-HCV agents that have shown great promise in HCV patients – the cycloph作者: 共同給與 時(shí)間: 2025-3-27 15:07
Antiviral Drug Resistance in Herpesviruses) and varicella-zoster virus (VZV) infections. The modest activity of ACV against human cytomegalovirus (HCMV) has prompted the development of another nucleoside analogue, ganciclovir (GCV), for the management of systemic and organ-specific HCMV diseases. Second-line agents such as the pyrophosphate作者: 狂熱語(yǔ)言 時(shí)間: 2025-3-27 18:02
Quasispecies and Drug Resistance features of RNA viral quasispecies such as internal interactions within mutant spectra and the effect of population size and bottleneck events as they affect the frequency of inhibitor-escape mutants. Genetic barriers to resistance and fitness cost of specific amino acid substitutions involved in r作者: synovitis 時(shí)間: 2025-3-27 23:16 作者: 生命層 時(shí)間: 2025-3-28 06:03
The Mechanisms of Resistance to β-Lactam Antibiotics antibacterials is the β-lactams that target the transpeptidase enzymes, which are responsible for cross-linking the peptidoglycan cell wall. There are over 34 FDA-approved β-lactams which together constitute ~50 % of all antibiotic prescriptions worldwide (Tahlan K and Jensen SE, J Antibiot (Tokyo)作者: 贊成你 時(shí)間: 2025-3-28 09:28
Antibiotic Resistance and Tolerance in Bacterial Biofilmss are ubiquitous in the natural and industrial environment, their importance in human infections has only been fully recognized in the past few decades. Biofilm-associated bacteria typically cause subacute and chronic infections. Many bacterial pathogens, such as . readily form biofilms, and . which作者: 門閂 時(shí)間: 2025-3-28 14:01
Strategies for Circumventing Bacterial Resistance Mechanismsmised but is now found both in and out the boundaries of the hospital. Preserving the efficacy of the antibacterials we have, in order to secure the time needed to discover and develop new antibacterials, will require abrupt change: in the way antibacterials are dispensed and disposed, in the criter作者: 廣大 時(shí)間: 2025-3-28 17:21
Drug-Resistant Tuberculosisrbidity and mortality in many parts of the world. In 2012, 8.6 million people became sick with tuberculosis, and 1.3 million died from this curable disease (World Health Organization 2013a). While the majority of cases are caused by strains susceptible to all antituberculosis antibiotics, drug resis作者: 格子架 時(shí)間: 2025-3-28 21:07
The Biochemistry of Quinoline Antimalarial Drug Resistanceresistance. However, additional facets to resistance biochemistry are emerging, and it is now clear that multiple quinoline drug resistance phenotypes exist in different regions of the globe. Different public health policies and drug use histories across the globe, along with natural genetic drift, 作者: GRACE 時(shí)間: 2025-3-28 23:57
Drug Resistance in ,o vaccine available yet, the control of these parasites relies solely on chemotherapy. Low-cost antimony-derived compounds remain the primary antileishmanial treatment in most developing countries. Increasing drug resistance towards these molecules has forced the use of alternative therapies in high作者: Dysarthria 時(shí)間: 2025-3-29 06:49 作者: ROOF 時(shí)間: 2025-3-29 07:13 作者: Fibrin 時(shí)間: 2025-3-29 12:16
Seif Emseih,Ghassan Soleiman Abu-Sittahe risk of liver disease progression, including cirrhosis, hepatic failure, and hepatocellular carcinoma. Nucleos(t)ide analogue monotherapy is commonly used as first-line therapy, and most patients will require long-term antiviral therapy. As for all direct-acting antiviral agents, the emergence of 作者: strdulate 時(shí)間: 2025-3-29 18:20 作者: 蚊子 時(shí)間: 2025-3-29 21:57
https://doi.org/10.1007/978-981-97-2504-5tagens of retroviral genomes. In humans, the APOBEC3 family comprises seven different proteins (APOBEC3A [A3A] to A3H), whose cytidine deaminase activity – if left unchecked – results in extensive mutagenesis of the HIV-1 genome. There is emerging evidence that cytidine deaminases other than A3G pla作者: MERIT 時(shí)間: 2025-3-30 03:12
Assessing the magnitude of the problemt accomplished by combining several drugs with potent antiviral activity across multiple genotypes, with each possessing a high barrier to resistance, different mechanisms of action, and no cross-resistance. A novel class of anti-HCV agents that have shown great promise in HCV patients – the cycloph作者: adequate-intake 時(shí)間: 2025-3-30 06:48 作者: incisive 時(shí)間: 2025-3-30 09:12
https://doi.org/10.1057/9781403978264 features of RNA viral quasispecies such as internal interactions within mutant spectra and the effect of population size and bottleneck events as they affect the frequency of inhibitor-escape mutants. Genetic barriers to resistance and fitness cost of specific amino acid substitutions involved in r作者: 神圣不可 時(shí)間: 2025-3-30 12:38
The European Context of the Wars,he selective pressure of therapy. Antiviral drug targets especially have a high mutational plasticity due to the diverse genetic viral population. An ideal antiviral inhibitor should be robust against these quasispecies. Fortunately, a therapeutic target can be evolutionarily constrained by the biol作者: Ringworm 時(shí)間: 2025-3-30 16:49
The Church and the Wars of the Roses, antibacterials is the β-lactams that target the transpeptidase enzymes, which are responsible for cross-linking the peptidoglycan cell wall. There are over 34 FDA-approved β-lactams which together constitute ~50 % of all antibiotic prescriptions worldwide (Tahlan K and Jensen SE, J Antibiot (Tokyo)
