標(biāo)題: Titlebook: HSP70 in Human Diseases and Disorders; Alexzander A. A. Asea,Punit Kaur Book 2018 Springer International Publishing AG, part of Springer N [打印本頁(yè)] 作者: 去是公開(kāi) 時(shí)間: 2025-3-21 16:16
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders影響因子(影響力)
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders被引頻次
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders被引頻次學(xué)科排名
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders年度引用
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders年度引用學(xué)科排名
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders讀者反饋
書(shū)目名稱(chēng)HSP70 in Human Diseases and Disorders讀者反饋學(xué)科排名
作者: LATER 時(shí)間: 2025-3-21 21:41
Hsp70-Family Proteins and Neurodegenerative Diseasesunctional signaling mechanisms is not an option for the brain. Neurons are thusly dependent on the collective cellular machinery of the molecular chaperones. Hsp70, a molecular chaperone which hydrolyzes ATP to fold proteins into a functional state, has been implicated as both a driver of disease pa作者: 地牢 時(shí)間: 2025-3-22 02:24 作者: Entirety 時(shí)間: 2025-3-22 06:54
Involvement of Heat Shock Protein 70 (Hsp70) in Gastrointestinal Cancersr all forms of life on earth. Misfolded proteins are refolded with the aid of Hsp and proteins which are damaged beyond repair are eliminated with assistance from Hsp. Hsp are known as molecular chaperones for their cytoprotective roles. In cancer cells the Hsp are frequently overexpressed and are a作者: 發(fā)芽 時(shí)間: 2025-3-22 11:34 作者: 謊言 時(shí)間: 2025-3-22 13:04 作者: 調(diào)色板 時(shí)間: 2025-3-22 20:21
Double Face of eHsp70 in Front of Different Situationsular one constitutively expressed member (Hsc70) and another one inducibly expressed under several stress conditions (Hsp70). To date, the intracellular functions of Hsp70 are well defined, and increasing evidences establish its roles in the extracellular environment, such as cytoprotection and immu作者: aspersion 時(shí)間: 2025-3-22 21:56 作者: FICE 時(shí)間: 2025-3-23 02:00 作者: Hemiparesis 時(shí)間: 2025-3-23 08:23 作者: FUME 時(shí)間: 2025-3-23 13:43 作者: Supplement 時(shí)間: 2025-3-23 17:49 作者: 異常 時(shí)間: 2025-3-23 19:06 作者: 別炫耀 時(shí)間: 2025-3-23 22:28
Heat Shock Protein 70 and Other Heat Shock Proteins in Diseased Retinance in protein folding, maintaining mitochondrial homeostasis, suppressing proinflammatory cytokines, resisting ischemic damage and protecting cells from apoptotic and necrotic death. This chapter discusses the important roles of HSP, particularly HSP70 in enhancing the survival of neurons in retina作者: 松軟 時(shí)間: 2025-3-24 02:47 作者: 享樂(lè)主義者 時(shí)間: 2025-3-24 07:20 作者: JEER 時(shí)間: 2025-3-24 10:39
https://doi.org/10.1007/978-94-009-7930-7rotein homeostasis (proteostasis). It has been shown that failure of protein quality control system, formation of protein aggregates and their ectopic accumulation in the neuronal cells is the common pathological hallmark of most of the neurodegenerative diseases such as Alzheimer’s disease (AD), Pa作者: Patrimony 時(shí)間: 2025-3-24 15:41 作者: 我吃花盤(pán)旋 時(shí)間: 2025-3-24 22:42 作者: 膽小懦夫 時(shí)間: 2025-3-25 02:32
https://doi.org/10.1007/978-1-4613-0811-9r all forms of life on earth. Misfolded proteins are refolded with the aid of Hsp and proteins which are damaged beyond repair are eliminated with assistance from Hsp. Hsp are known as molecular chaperones for their cytoprotective roles. In cancer cells the Hsp are frequently overexpressed and are a作者: 落葉劑 時(shí)間: 2025-3-25 06:43
Umesh Hodeghatta Rao,Umesha Nayakeat shock or other stressors. The major groups, which are classified based on their molecular weight, include HSP27, HSP40, HSP60, HSP70, HSP90, and large HSP (HSP110 and glucose-regulated protein 170). The human HSP70 family is consists of 13 members and five of them have a strong association with 作者: 迎合 時(shí)間: 2025-3-25 11:11 作者: 一再煩擾 時(shí)間: 2025-3-25 14:48
https://doi.org/10.1057/9780230113992ular one constitutively expressed member (Hsc70) and another one inducibly expressed under several stress conditions (Hsp70). To date, the intracellular functions of Hsp70 are well defined, and increasing evidences establish its roles in the extracellular environment, such as cytoprotection and immu作者: 傀儡 時(shí)間: 2025-3-25 19:44 作者: 不可知論 時(shí)間: 2025-3-25 22:21
pecially the capacity (i) to induce the presentation and cross-presentation of associated or client proteins and, (ii) to control myeloid cell activation. Several studies were focused on the identification of HSP70-binding elements that contribute to their immune properties. A general consensus was 作者: Vertical 時(shí)間: 2025-3-26 01:47
https://doi.org/10.1007/3-540-33156-5he surrounding aqueous cytoplasm or nucleoplasm through a process known as liquid-liquid phase separation. In healthy cells, ribonucleoprotein (RNP) granules are highly dynamic compartments. In contrast, in aging cells or due to environmental stresses or genetic mutations, RNP granules, in particula作者: 種植,培養(yǎng) 時(shí)間: 2025-3-26 08:16 作者: anesthesia 時(shí)間: 2025-3-26 09:42 作者: 蜿蜒而流 時(shí)間: 2025-3-26 13:36
https://doi.org/10.1007/978-3-642-48423-0ressors including heat, oxidative and chemical stress. Expression of HSP helps in numerous reparative processes including the refolding of damaged proteins and removal of irreparably damaged proteins that would accumulate and initiate cellular death or apoptosis. A growing body of evidence in recent作者: 星星 時(shí)間: 2025-3-26 20:10 作者: Electrolysis 時(shí)間: 2025-3-26 21:00
The Infra-red Spectra of Complex Moleculesf stress physical, biological or chemical. Under stress conditions, HSP70 recognize and bind to the unstable protein substrates and protect them from denaturation and aggregation. Besides, HSP70 are also essential during normal growth where they assist in folding of nascent proteins, degradation of 作者: Osteons 時(shí)間: 2025-3-27 02:53
The Infrared Spectra of Complex MoleculesD)-type neuropathologies. It was demonstrated that intranasally injected exogenous Hsp70 (eHsp70) effectively bypassed the blood-brain barrier and penetrates brain regions of the model animals. It was shown that chronic administration of eHsp70 decreases beta-amyloid level and the number of Aβ-plaqu作者: 地名表 時(shí)間: 2025-3-27 06:18 作者: cathartic 時(shí)間: 2025-3-27 13:18 作者: arabesque 時(shí)間: 2025-3-27 16:20
Involvement of Heat Shock Protein 70 (Hsp70) in Gastrointestinal Cancersn the role of molecular chaperones in particular heat shock protein 70 (Hsp70) in human gastrointestinal cancers along with their therapeutic targeting. This review will focus on the role of Hsp 70 and related chaperones in several gastrointestinal cancers such as pancreatic, gastric, and liver canc作者: 撫慰 時(shí)間: 2025-3-27 18:13 作者: encyclopedia 時(shí)間: 2025-3-27 23:34 作者: Abrade 時(shí)間: 2025-3-28 04:33
HSP70 Is a Major Contributor to the MHCII Ligandome and Inducer of Regulatory T Cells molecules. MHCII peptide elution profiles obtained from cells in a steady state have also revealed the dominating presence of HSP70 derived peptides in MHC class II molecules. For these reasons HSP70 is one of the most frequent cytosolic/nuclear MHCII natural ligand sources. HSP70, when presented b作者: ectropion 時(shí)間: 2025-3-28 09:12
Immune Properties of HSP70accines, especially in the treatment of cancers and chronic viral infections. Although HSP70 constitute potent vaccine vehicles in different preclinical models, clinical studies remain disappointing. The fact that the immune properties of HSP70 have not been totally clarified may explain their relat作者: occult 時(shí)間: 2025-3-28 14:15
Molecular Chaperones Regulating the Dynamics, Composition and Functionality of RNP Granules: Implica conversion may represent a valid approach to combat these diseases..In this book chapter, we summarize the current knowledge about stress granule formation. We focus on recent findings demonstrating that liquid-like SGs can sequester aggregation-prone misfolded proteins with detrimental consequence作者: Infantry 時(shí)間: 2025-3-28 15:58 作者: 頭腦冷靜 時(shí)間: 2025-3-28 22:39
Heat Shock Proteins in the Kidney: What Is Known About Their Role in Kidney Disease of HSP in prevention of kidney injury will be crucial if translation from the laboratory to patient bedside has to occur. This article aims to be a review of heat shock protein and its relevance to kidney disease.作者: 火車(chē)車(chē)輪 時(shí)間: 2025-3-29 02:41
Intranasal Administration of Hsp70: Molecular and Therapeutic Consequencespofuscin and modulates the activity of UPS by increasing expression of several proteasome subunits including immunoproteasome subunit β5i. Deep sequencing studies exploring brain regions of AD-model?– 5XFAD mice treated with eHsp70 revealed candidate genes and signal pathways probably underlying ben作者: 造反,叛亂 時(shí)間: 2025-3-29 04:06
https://doi.org/10.1007/978-94-009-7930-7 to different cellular compartments, cell death and cell cycle regulation etc. Several recent studies have suggested that Hsp70 can be a key molecule to address the major pathologies associated with neurodegenerative diseases. This chapter briefly summarizes the Hsp70 and its possible role during ne作者: 發(fā)炎 時(shí)間: 2025-3-29 09:34 作者: 導(dǎo)師 時(shí)間: 2025-3-29 13:51
https://doi.org/10.1007/978-1-4613-0811-9n the role of molecular chaperones in particular heat shock protein 70 (Hsp70) in human gastrointestinal cancers along with their therapeutic targeting. This review will focus on the role of Hsp 70 and related chaperones in several gastrointestinal cancers such as pancreatic, gastric, and liver canc作者: OUTRE 時(shí)間: 2025-3-29 16:46 作者: 迎合 時(shí)間: 2025-3-29 22:49
https://doi.org/10.1007/978-1-349-23540-7ssion. Genetic polymorphism has been correlated with susceptibility to many diseases and association of HSP70 polymorphism in GC is no exception. This chapter deals with various functional roles of HSP70 and its implication in tumorigenesis, particularly gastric cancer.作者: 系列 時(shí)間: 2025-3-30 03:04
https://doi.org/10.1007/978-1-4615-2093-1 molecules. MHCII peptide elution profiles obtained from cells in a steady state have also revealed the dominating presence of HSP70 derived peptides in MHC class II molecules. For these reasons HSP70 is one of the most frequent cytosolic/nuclear MHCII natural ligand sources. HSP70, when presented b作者: GORGE 時(shí)間: 2025-3-30 05:36
accines, especially in the treatment of cancers and chronic viral infections. Although HSP70 constitute potent vaccine vehicles in different preclinical models, clinical studies remain disappointing. The fact that the immune properties of HSP70 have not been totally clarified may explain their relat作者: Osteons 時(shí)間: 2025-3-30 09:20 作者: 親屬 時(shí)間: 2025-3-30 12:35 作者: 獨(dú)白 時(shí)間: 2025-3-30 17:09
https://doi.org/10.1007/978-3-642-48423-0 of HSP in prevention of kidney injury will be crucial if translation from the laboratory to patient bedside has to occur. This article aims to be a review of heat shock protein and its relevance to kidney disease.作者: 引起 時(shí)間: 2025-3-30 21:59
The Infrared Spectra of Complex Moleculespofuscin and modulates the activity of UPS by increasing expression of several proteasome subunits including immunoproteasome subunit β5i. Deep sequencing studies exploring brain regions of AD-model?– 5XFAD mice treated with eHsp70 revealed candidate genes and signal pathways probably underlying ben作者: 負(fù)擔(dān) 時(shí)間: 2025-3-31 01:37
1877-1246 udents and residents, clinical and basic science researchers, postdoctoral fellows and graduate students in the fields of Medicine, Physiology, Clinical Trials, Biotechnology, Molecular Medicine and Pathology..978-3-030-07801-0978-3-319-89551-2Series ISSN 1877-1246 Series E-ISSN 1877-1254 作者: 演繹 時(shí)間: 2025-3-31 05:15 作者: 雄偉 時(shí)間: 2025-3-31 12:37
978-3-030-07801-0Springer International Publishing AG, part of Springer Nature 2018
