標題: Titlebook: HCV/Oxidative Stress and Liver Disease; Kiwamu Okita (Professor and Chairman) Conference proceedings 2003 Springer Japan 2003 DNA.RNA.canc [打印本頁] 作者: 弄碎 時間: 2025-3-21 18:55
書目名稱HCV/Oxidative Stress and Liver Disease影響因子(影響力)
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書目名稱HCV/Oxidative Stress and Liver Disease網(wǎng)絡公開度學科排名
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書目名稱HCV/Oxidative Stress and Liver Disease讀者反饋學科排名
作者: NAUT 時間: 2025-3-21 22:07
Role of Core Protein-Induced Oxidative Stress in the Pathogenesis of Hepatitis C,of core-induced oxidative stress include DNA damage, lipid peroxidation, cell cycle dysregulation, and stellate cell activation. These in turn contribute to cell death, fibrogenesis, and carcinogenesis, as seen in patients with chronic hepatitis C. Modulation of oxidative stress may therefore have t作者: 上坡 時間: 2025-3-22 03:35 作者: Hallowed 時間: 2025-3-22 07:18 作者: 預示 時間: 2025-3-22 09:57
Role of Hepatitis C Virus in Hepatocarcinogenesis: Oxidative Stress in the Absence of Inflammation,ample, colorectal cancer, the accumulation of a set of genetic aberrations may also be necessary for the multistage development of HCC. However, the HCV core protein, to which an oncogenic potential is ascribed, may allow some of the multiple stages of hepatocarcinogenesis to be skipped. Unlike in t作者: Diaphragm 時間: 2025-3-22 16:42
,Reduced Chemical Hepatocarcinogenesis in Interferon-γ Receptor Knockout Mice,wer hepatocellular carcinomas than IFN-α/βR KO and wild-type (wt) mice, although the diameters of the largest liver tumors were not significantly different among the three lineages. Interestingly, immunohistochemical studies demonstrated that the proportions of monocytes/macrophages were greatly red作者: decipher 時間: 2025-3-22 19:00
Fewer Somatic Mutations of Mitochondrial DNA in Noncancerous Liver Tissue of Patients with Hepatoce larger group, some had been treated with IFN, but none had the desired response. The number of mutations in cancerous tissues was significantly smaller for patients with a biochemical or complete response to IFN than for patients with no response to IFN or no history of treatment with IFN. At prese作者: interlude 時間: 2025-3-23 00:05
Hepatic Iron Staining in Chronic Hepatitis C Patients with Low HCV RNA Levels as a Predictive Markenalysis showed that TIS was an independent factor relating to the response to IFN therapy . 0.0062). The TIS correlated significantly with serum ferritin levels (. = 0.637, . < 0.001), but not with any other parameter. Conclusions: Among CH-C patients with low HCV RNA levels, the TIS of the liver ma作者: 無聊的人 時間: 2025-3-23 03:37 作者: 無價值 時間: 2025-3-23 08:08
ocellular carcinoma, and oxidative stress in the absence of inflammation in hepatocarcinogenesis. This collection of papers from the Yamaguchi Symposium creates a valuable reference resource for physicians and hepatologists..978-4-431-67007-0978-4-431-67005-6作者: Anecdote 時間: 2025-3-23 09:45
The Future of Global Economic Governanceotal amounts of lipid peroxidation products. When fed alcohol for 5 weeks, male TgM had higher amounts of lipid peroxidation products than nonTgM. In female mice, lipid peroxidation products were high under all conditions. Aspartate aminotransferase and alanine aminotransferase values did not differ作者: JECT 時間: 2025-3-23 14:40 作者: curettage 時間: 2025-3-23 18:41 作者: MELON 時間: 2025-3-23 22:26
Mark Loon,Jim Stewart,Stefanos Nachmiassay. Among seven HCV proteins investigated, core protein had the strongest influence on intracellular signaling, especially for the SRE-, AP-1-, NFKB-, and p53-associated pathways. Core protein promoted Bc1-x. expression through the mitogen-activated protein kinase (MAPK) pathway and inhibited apopt作者: 驚呼 時間: 2025-3-24 04:17 作者: 未成熟 時間: 2025-3-24 07:32
The Future of High-Skilled Workerswer hepatocellular carcinomas than IFN-α/βR KO and wild-type (wt) mice, although the diameters of the largest liver tumors were not significantly different among the three lineages. Interestingly, immunohistochemical studies demonstrated that the proportions of monocytes/macrophages were greatly red作者: SPASM 時間: 2025-3-24 14:41 作者: agitate 時間: 2025-3-24 15:48 作者: dysphagia 時間: 2025-3-24 20:00 作者: 嬉耍 時間: 2025-3-25 00:59 作者: 世俗 時間: 2025-3-25 03:48
Giovanni Bignami,Andrea Sommarivae guanylate cyclase as a gas signal transducer, although whether this heme protein serves as an authentic receptor for CO remains unknown. This chapter focuses on recent developments, collected from both experimental and clinical settings, regarding both the physiologic and pathophysiologic roles of CO as a regulator of hepatobiliary functions.作者: Charade 時間: 2025-3-25 10:09
Carbon Monoxide as a Gaseous Regulator of Liver Microcirculation,e guanylate cyclase as a gas signal transducer, although whether this heme protein serves as an authentic receptor for CO remains unknown. This chapter focuses on recent developments, collected from both experimental and clinical settings, regarding both the physiologic and pathophysiologic roles of CO as a regulator of hepatobiliary functions.作者: Glucose 時間: 2025-3-25 11:39 作者: Irascible 時間: 2025-3-25 16:36 作者: arthrodesis 時間: 2025-3-25 23:45
Hepatic Iron Accumulation and Incidence of Hepatocellular Carcinoma in Patients with Chronic Hepatinoma (HCC), but no definite relationship has been established. Therefore, a randomized control study is necessary to clarify whether or not the development of HCC is reduced by removing hepatic iron by extensive phlebotomy in chronic hepatitis C.作者: 侵蝕 時間: 2025-3-26 02:11 作者: 離開就切除 時間: 2025-3-26 07:54
The Future of Global Economic Governancec hepatotoxicity are unknown; however, oxidative stress appears to play a role in the pathogenesis of both alcoholic liver disease and chronic hepatitis C. The aim of this study was to determine whether hepatitic C virus (HCV) protein expression by itself alters alcohol-induced liver injury. Mice vo作者: strdulate 時間: 2025-3-26 09:45 作者: 指派 時間: 2025-3-26 15:30 作者: Aerophagia 時間: 2025-3-26 17:23 作者: Ophthalmoscope 時間: 2025-3-26 22:44 作者: Expediency 時間: 2025-3-27 02:19 作者: commonsense 時間: 2025-3-27 08:50 作者: HEAVY 時間: 2025-3-27 13:21
Habib M. Fardoun,Kevin J. Downing,Mandy Moks. Besides the serum HCV RNA level or HCV genotype, hepatic iron concentrations are thought to be correlated with the subsequent response to IFN therapy. In the present study, we evaluated serum iron, ferritin, and hepatic iron staining in patients with low HCV RNA levels as a predictive marker for 作者: bizarre 時間: 2025-3-27 13:39 作者: 牢騷 時間: 2025-3-27 19:28
Giovanni Bignami,Andrea Sommarivasuch as sinusoids and to thereby maintain low vascular resistance. CO seems to be released mainly from hepatocytes that express HO-2, the constitutive enzyme, and also HO-1, induced under stress conditions. CO released into the space of Disse accesses the hepatic stellate cells, which express solubl作者: ARY 時間: 2025-3-27 21:56 作者: Chipmunk 時間: 2025-3-28 05:09 作者: Physiatrist 時間: 2025-3-28 08:55
Role of Core Protein-Induced Oxidative Stress in the Pathogenesis of Hepatitis C,is, and hepatocellular carcinoma. Liver injury results from a combination of immunemediated and direct viral effects. The HCV core protein has been shown to produce oxidative stress when overexpressed in multiple different cell lines as well as in the livers of transgenic mice. The mechanisms of cor作者: 階層 時間: 2025-3-28 11:18
Hepatitis C Virus Core-Mediated Alteration of Gene Expression and Signal Transduction in the Host Cin on the cell cycle machinery and the Janus kinase (JAK)-signal transducer and activator transcription (STAT) factor signal transduction pathway in the host cell. The analysis of the cell cycle profile showed that HCV core protein prevented the transition from the G1 to the S phase. pRb phosphoryla作者: AWE 時間: 2025-3-28 14:50 作者: 刪除 時間: 2025-3-28 22:39
Role of Hepatitis C Virus in Hepatocarcinogenesis: Oxidative Stress in the Absence of Inflammation,t of hepatocellular carcinoma (HCC). In the pathogenesis of HCC associated with HCV, it remains controversial whether the virus plays a direct role or merely an indirect role. Through the use of a transgenic mouse model established by us, it has become evident that the core protein of HCV has an onc作者: Stagger 時間: 2025-3-29 01:22
,Reduced Chemical Hepatocarcinogenesis in Interferon-γ Receptor Knockout Mice,infiltration was observed in the livers of mice treated with chemical hepatocarcinogens, the pathophysiological role of the inflammatory response is not well defined in the process of carcinogenesis. To approach this question, mice were exposed to a chemical hepatocarcinogen, diethylnitrosamine (DEN作者: AGATE 時間: 2025-3-29 05:17
Fewer Somatic Mutations of Mitochondrial DNA in Noncancerous Liver Tissue of Patients with Hepatocetochondrial DNA (mtDNA) than in nuclear DNA. In this study, we examined the number of mtDNA mutations in paired cancerous and noncancerous tissue from the same resected specimen from 59 patients with Hepatitis C virus-related HCC. Some patients had undergone interferon (IFN) therapy. Residues of the
