標(biāo)題: Titlebook: Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins; Raphael Enoque Ferraz de Paiva Book 2018 Sp [打印本頁] 作者: 掩飾 時間: 2025-3-21 18:02
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins影響因子(影響力)
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins影響因子(影響力)學(xué)科排名
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins網(wǎng)絡(luò)公開度
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins被引頻次
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins被引頻次學(xué)科排名
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins年度引用
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins年度引用學(xué)科排名
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins讀者反饋
書目名稱Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins讀者反饋學(xué)科排名
作者: 鴕鳥 時間: 2025-3-21 21:20
Probing Gold: X-Ray Absorption Spectroscopyra. The viral NCp7 ZnF2 was compared to the human transcription factor Sp1 ZnF3.?We examine the effects of the zinc coordination sphere in dictating reactivity and delineating the intimate mechanisms of metal ions substitution in a ZnF template. In the case of Au(I) compounds, we confirm the Lewis a作者: prediabetes 時間: 2025-3-22 04:12
Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins作者: 符合規(guī)定 時間: 2025-3-22 07:35
https://doi.org/10.1007/978-1-4419-6481-6ra. The viral NCp7 ZnF2 was compared to the human transcription factor Sp1 ZnF3.?We examine the effects of the zinc coordination sphere in dictating reactivity and delineating the intimate mechanisms of metal ions substitution in a ZnF template. In the case of Au(I) compounds, we confirm the Lewis a作者: 厭倦嗎你 時間: 2025-3-22 10:28
https://doi.org/10.1007/978-3-030-00853-6Gold Complexes; Nucleocapsid Protein NCp7; Human Trabscription Factor Protein 1 Sp1; Zinc Finger Protei作者: 影響帶來 時間: 2025-3-22 16:58 作者: 影響帶來 時間: 2025-3-22 17:02
Au(III) Series with ,C,N and ,N,N′ Ligandscesses. On the other hand, stabilizing Au(III) represents an interesting synthetic challenge, given the wide variety of possible strategies available.?For that reason, we decided to explore the stabilization of Au(III) using the N^C donor 2-benzylpyridine (bnpy) ligand and compare it to the classic bipy-like N^N coordination motif.作者: Slit-Lamp 時間: 2025-3-23 00:23 作者: 金絲雀 時間: 2025-3-23 02:47 作者: 諂媚于性 時間: 2025-3-23 06:03
Gold(I,III) Complexes Designed for Selective Targeting and Inhibition of Zinc Finger Proteins978-3-030-00853-6Series ISSN 2190-5053 Series E-ISSN 2190-5061 作者: Nefarious 時間: 2025-3-23 12:56 作者: Mundane 時間: 2025-3-23 14:21 作者: averse 時間: 2025-3-23 19:51
Probing Gold: X-Ray Absorption Spectroscopylity to specifically probe the geometry around the metal absorber. Additionally, XAS spectra are sensitive to the electronic density on the mental center. As consequence, it represents an extremely powerful technique that is able to distinguish between oxidation states and coordination spheres of a 作者: 過剩 時間: 2025-3-23 22:25 作者: 混雜人 時間: 2025-3-24 03:18
Au(III) Series with ,C,N and ,N,N′ Ligandscesses. On the other hand, stabilizing Au(III) represents an interesting synthetic challenge, given the wide variety of possible strategies available.?For that reason, we decided to explore the stabilization of Au(III) using the N^C donor 2-benzylpyridine (bnpy) ligand and compare it to the classic 作者: 迅速成長 時間: 2025-3-24 07:24
“Dual-Probe” X-Ray Absorption Spectroscopycontext of the interaction of metallodrugs with a metalloprotein, XAS can be used in a “dual-probe” approach, by monitoring both the absorption edge of the metal complex and also the edge of the metal present in the metalloprotein. As a proof-of-concept, we evaluated the interaction of Au(III) compl作者: 裂口 時間: 2025-3-24 12:31 作者: 平庸的人或物 時間: 2025-3-24 17:12 作者: DRAFT 時間: 2025-3-24 20:27
https://doi.org/10.1007/978-1-4419-6481-6lity to specifically probe the geometry around the metal absorber. Additionally, XAS spectra are sensitive to the electronic density on the mental center. As consequence, it represents an extremely powerful technique that is able to distinguish between oxidation states and coordination spheres of a 作者: Arthr- 時間: 2025-3-25 00:36
https://doi.org/10.1007/978-1-4614-1323-3drug throughout the past decade. Regardless of the potent cytotoxicity observed for auranofin, there are many reports on lack of selectivity.?Inspired by the structure of auranofin, and aiming to improve the cytotoxic selectivity, we decided to evaluate the cytotoxicity of the Au(I)-phosphine series作者: plasma-cells 時間: 2025-3-25 07:16 作者: Basal-Ganglia 時間: 2025-3-25 08:16 作者: 舉止粗野的人 時間: 2025-3-25 15:10 作者: Irksome 時間: 2025-3-25 17:34
Au(I)-Phosphine Series Designectrophiles, and we demonstrate that chemoselective auration is useful for probing the nucleocapsid topography. We also examined for comparison the “standard” gold-phosphine compound auranofin which contains a thiosugar co-ligand.作者: Engulf 時間: 2025-3-25 23:28 作者: Eeg332 時間: 2025-3-26 02:45
Book 2018plores gold(I)-phosphine, gold(III) complexes with N^N and C^N donors as inhibitors of the HIV-1 nucleocapsid protein (NCp7), in comparison to the human transcription factor Sp1. To determine the coordination sphere of the gold adducts formed by interaction with ZnFs, two innovative approaches are u作者: 知識分子 時間: 2025-3-26 06:45 作者: 胎兒 時間: 2025-3-26 09:07
https://doi.org/10.1007/978-3-540-85849-2exes with ZnFs by monitoring the Au L3-edge and also the Zn K-edge. Furthermore, given the unique stability and reactivity of the Au(C^N) coordination motif discussed in Part II—Chap. ., the interaction of the compound [Au(bnpy)Cl2] with ZnFs was also studied by XAS.作者: 相容 時間: 2025-3-26 12:44
Probing the Protein: Ion Mobility Spectrometryed with collision induced dissociation (CID).?This approach allowed inequivocal elucidation of specific binding sites and modes of gold-modified NCp7 (ZnF2) and Sp1 (ZnF3). While linear Cys-Au-Cys is indicated for NCp7 (ZnF2), a Cys-Au-His mode is indicated for the Sp1 (ZnF3) case.作者: 共棲 時間: 2025-3-26 20:19
“Dual-Probe” X-Ray Absorption Spectroscopyexes with ZnFs by monitoring the Au L3-edge and also the Zn K-edge. Furthermore, given the unique stability and reactivity of the Au(C^N) coordination motif discussed in Part II—Chap. ., the interaction of the compound [Au(bnpy)Cl2] with ZnFs was also studied by XAS.作者: Indicative 時間: 2025-3-27 00:07
Book 2018yield valuable structural information regarding the coordination sphere of gold in the adducts. In addition, the organometallic compound [Au (bnpy)Cl2] is evaluated. The system is shown to be capable of inhibiting ZnFs by means of C–S coupling..作者: 一再困擾 時間: 2025-3-27 02:13
https://doi.org/10.1007/978-1-4614-1323-3 the phosphine ligand, σ-donating properties and lability of the co-ligands L (L?=?Cl or 4-dimethylaminopyridine, dmap) and overall charge of the compounds (neutral vs. cationic) are also expected to play a role in cytotoxic response, establishing an interesting set of parameters that can be correlated.作者: Dissonance 時間: 2025-3-27 09:05 作者: 讓步 時間: 2025-3-27 13:23
On the solution structure of galaninf insulin release results from the action of galanin on potassium channels and indirectly on calcium channels in the β-cells of the pancreas (de Weille et al. 1988, Dunne al. 1989, Nilsson et al. 1989).作者: RAG 時間: 2025-3-27 16:05
1064-3745 y reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls...Authoritative and practical, .Cell Viability Assays: Methods and Protocols .aims to ensure successful results in the further study of this vital field..978-1-4939-8352-0978-1-4939-6960-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 焦慮 時間: 2025-3-27 18:13
Peter Z. Reveszgie, die sogenannten Neurowissenschaften (Neurophysiologie, Neuroendokrinologie, Neuroimmunologie) sowie die entsprechenden medizinisch-klinischen Disziplinen; spannend ist sie, weil hier in exemplarischer Form an einem neuen, biopsychosozialen Krankheitskonzept gearbeitet werden kann. Dieser zuletz作者: Jocose 時間: 2025-3-28 00:34 作者: Adenoma 時間: 2025-3-28 05:22 作者: 單調(diào)女 時間: 2025-3-28 09:14 作者: Interim 時間: 2025-3-28 12:08 作者: BUCK 時間: 2025-3-28 17:12
Radiation Effects in Transistors Betriebspunkt besch?ftigt. In diesem Kapitel wollen wir uns nun gerade Regelkreisen zuwenden, deren nichtlineare Eigenschaften entscheidend das Kreisverhalten bestimmen, bei denen also eine Linearisierung wenig sinnvoll w?re. Wie kommen solche wesentlichen nichtlinearen Effekte zustande?
